메뉴 건너뛰기




Volumn 53, Issue 1-2, 2010, Pages 1-10

Regulation of angiogenesis by a small GTPase Rap1

Author keywords

Blood vessel formation; Endothelial barrier; Endothelium; FGF; VEGF

Indexed keywords

BONE MARROW PROTEIN TYROSINE KINASE IN CHOMOSOME X; CELL ADHESION MOLECULE; FIBROBLAST GROWTH FACTOR 2 RECEPTOR; GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATASE; INTEGRIN; ISOPROTEIN; JUNCTIONAL ADHESION MOLECULE A; JUNCTIONAL ADHESION MOLECULE C; PROTEIN TYROSINE KINASE; RAP1 PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 77952549816     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2010.03.003     Document Type: Review
Times cited : (32)

References (132)
  • 1
    • 0041816053 scopus 로고    scopus 로고
    • p130(Cas) couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration
    • Abassi Y.A., Rehn M., Ekman N., Alitalo K., and Vuori K. p130(Cas) couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration. J. Biol. Chem. 278 (2003) 35636-35643
    • (2003) J. Biol. Chem. , vol.278 , pp. 35636-35643
    • Abassi, Y.A.1    Rehn, M.2    Ekman, N.3    Alitalo, K.4    Vuori, K.5
  • 4
    • 5444230311 scopus 로고    scopus 로고
    • Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors
    • Arthur W.T., Quilliam L.A., and Cooper J.A. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. J. Cell Biol. 167 (2004) 111-122
    • (2004) J. Cell Biol. , vol.167 , pp. 111-122
    • Arthur, W.T.1    Quilliam, L.A.2    Cooper, J.A.3
  • 7
    • 27844507514 scopus 로고    scopus 로고
    • E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function
    • Balzac F., Avolio M., Degani S., Kaverina I., Torti M., Silengo L., Small J.V., and Retta S.F. E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function. J. Cell Sci. 118 (2005) 4765-4783
    • (2005) J. Cell Sci. , vol.118 , pp. 4765-4783
    • Balzac, F.1    Avolio, M.2    Degani, S.3    Kaverina, I.4    Torti, M.5    Silengo, L.6    Small, J.V.7    Retta, S.F.8
  • 8
    • 0037067748 scopus 로고    scopus 로고
    • Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton
    • Bertoni A., Tadokoro S., Eto K., Pampori N., Parise L.V., White G.C., and Shattil S.J. Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton. J. Biol. Chem. 277 (2002) 25715-25721
    • (2002) J. Biol. Chem. , vol.277 , pp. 25715-25721
    • Bertoni, A.1    Tadokoro, S.2    Eto, K.3    Pampori, N.4    Parise, L.V.5    White, G.C.6    Shattil, S.J.7
  • 9
    • 70349335654 scopus 로고    scopus 로고
    • Control of cell adhesion dynamics by Rap1 signaling
    • Boettner B., and Van Aelst L. Control of cell adhesion dynamics by Rap1 signaling. Curr. Opin. Cell Biol. 21 (2009) 684-693
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 684-693
    • Boettner, B.1    Van Aelst, L.2
  • 10
    • 0027458513 scopus 로고
    • Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins
    • Bokoch G. Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins. Biochem. J. 289 (1993) 17-24
    • (1993) Biochem. J. , vol.289 , pp. 17-24
    • Bokoch, G.1
  • 11
    • 69249216479 scopus 로고    scopus 로고
    • EPAC proteins transduce diverse cellular actions of cAMP
    • Borland G., Smith B.O., and Yarwood S.J. EPAC proteins transduce diverse cellular actions of cAMP. Br. J. Pharm. 9999 (2009)
    • (2009) Br. J. Pharm. , vol.9999
    • Borland, G.1    Smith, B.O.2    Yarwood, S.J.3
  • 12
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • Bos J.L. Linking Rap to cell adhesion. Curr. Opin. Cell Biol. 17 (2005) 123-128
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 123-128
    • Bos, J.L.1
  • 14
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: critical elements in the control of small G proteins
    • Bos J.L., Rehmann H., and Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 129 (2007) 865-877
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 15
    • 0028362876 scopus 로고
    • Requirement of vascular integrin [alpha]v[beta]3 for angiogenesis
    • Brooks P.C., Clark R.A., and Cheresh D.A. Requirement of vascular integrin [alpha]v[beta]3 for angiogenesis. Science 264 (1994) 569-571
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 16
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 19
    • 0037329747 scopus 로고    scopus 로고
    • Cellular functions of the Rap1 GTP-binding protein: a pattern emerges
    • Caron E. Cellular functions of the Rap1 GTP-binding protein: a pattern emerges. J. Cell Sci. 116 (2003) 435-440
    • (2003) J. Cell Sci. , vol.116 , pp. 435-440
    • Caron, E.1
  • 20
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary L.A., Chang J.F., and Guan J.L. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J. Cell Sci. 109 (1996) 1787-1794
    • (1996) J. Cell Sci. , vol.109 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.L.3
  • 22
    • 41949111990 scopus 로고    scopus 로고
    • Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice
    • Chrzanowska-Wodnicka M., Kraus A.E., Gale D., White II G.C., and VanSluys J. Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice. Blood 111 (2008) 2647-2656
    • (2008) Blood , vol.111 , pp. 2647-2656
    • Chrzanowska-Wodnicka, M.1    Kraus, A.E.2    Gale, D.3    White II, G.C.4    VanSluys, J.5
  • 23
    • 33747393306 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice
    • Cooke V.G., Naik M.U., and Naik U.P. Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice. Arterioscl. Thromb. Vasc. Biol. 26 (2006) 2005-2011
    • (2006) Arterioscl. Thromb. Vasc. Biol. , vol.26 , pp. 2005-2011
    • Cooke, V.G.1    Naik, M.U.2    Naik, U.P.3
  • 24
    • 14944377651 scopus 로고    scopus 로고
    • Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase
    • Cullere X., Shaw S.K., Andersson L., Hirahashi J., Luscinskas F.W., and Mayadas T.N. Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood 105 (2005) 1950-1955
    • (2005) Blood , vol.105 , pp. 1950-1955
    • Cullere, X.1    Shaw, S.K.2    Andersson, L.3    Hirahashi, J.4    Luscinskas, F.W.5    Mayadas, T.N.6
  • 26
    • 33646557326 scopus 로고    scopus 로고
    • p130Cas: a versatile scaffold in signaling networks
    • Defilippi P., Di Stefano P., and Cabodi S. p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol. 16 (2006) 257-263
    • (2006) Trends Cell Biol. , vol.16 , pp. 257-263
    • Defilippi, P.1    Di Stefano, P.2    Cabodi, S.3
  • 27
  • 31
    • 0032498640 scopus 로고    scopus 로고
    • Integrin alpha vbeta 3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
    • Eliceiri B.P., Klemke R., Stromblad S., and Cheresh D.A. Integrin alpha vbeta 3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J. Cell Biol. 140 (1998) 1255-1263
    • (1998) J. Cell Biol. , vol.140 , pp. 1255-1263
    • Eliceiri, B.P.1    Klemke, R.2    Stromblad, S.3    Cheresh, D.A.4
  • 32
    • 0031825437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
    • Esser S., Lampugnani M., Corada M., Dejana E., and Risau W. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J. Cell Sci. 111 (1998) 1853-1865
    • (1998) J. Cell Sci. , vol.111 , pp. 1853-1865
    • Esser, S.1    Lampugnani, M.2    Corada, M.3    Dejana, E.4    Risau, W.5
  • 33
    • 0028979154 scopus 로고
    • Consequences of lack of [beta]1 integrin gene expression in mice
    • Fassler R., and Meyer M. Consequences of lack of [beta]1 integrin gene expression in mice. Genes Dev. 9 (1995) 1896-1908
    • (1995) Genes Dev. , vol.9 , pp. 1896-1908
    • Fassler, R.1    Meyer, M.2
  • 34
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N., and Kerbel R.S. Angiogenesis as a therapeutic target. Nature 438 (2005) 967-974
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 35
    • 34047175559 scopus 로고    scopus 로고
    • Targeting VEGF-A to treat cancer and age-related macular degeneration
    • Ferrara N., Mass R.D., Campa C., and Kim R. Targeting VEGF-A to treat cancer and age-related macular degeneration. Annu. Rev. Med. 58 (2007) 491-504
    • (2007) Annu. Rev. Med. , vol.58 , pp. 491-504
    • Ferrara, N.1    Mass, R.D.2    Campa, C.3    Kim, R.4
  • 36
    • 14244260906 scopus 로고    scopus 로고
    • Local activation of rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule localizes
    • Fujita H., Fukuhara S., Sakurai A., Yamagishi A., Kamioka Y., Nakaoka Y., Masuda M., and Mochizuki N. Local activation of rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule localizes. J. Biol. Chem. 280 (2005) 5022-5031
    • (2005) J. Biol. Chem. , vol.280 , pp. 5022-5031
    • Fujita, H.1    Fukuhara, S.2    Sakurai, A.3    Yamagishi, A.4    Kamioka, Y.5    Nakaoka, Y.6    Masuda, M.7    Mochizuki, N.8
  • 37
    • 11144305139 scopus 로고    scopus 로고
    • Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway
    • Fukuhara S., Sakurai A., Sano H., Yamagishi A., Somekawa S., Takakura N., Saito Y., Kangawa K., and Mochizuki N. Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol. Cell. Biol. 25 (2005) 136-146
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 136-146
    • Fukuhara, S.1    Sakurai, A.2    Sano, H.3    Yamagishi, A.4    Somekawa, S.5    Takakura, N.6    Saito, Y.7    Kangawa, K.8    Mochizuki, N.9
  • 40
    • 34548028024 scopus 로고    scopus 로고
    • VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
    • Garrett T.A., Van Buul J.D., and Burridge K. VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. Exp. Cell Res.. 313 (2007) 3285-3297
    • (2007) Exp. Cell Res.. , vol.313 , pp. 3285-3297
    • Garrett, T.A.1    Van Buul, J.D.2    Burridge, K.3
  • 41
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
    • 1223-U17
    • Gavard J., and Gutkind J.S. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat. Cell Biology. 8 (2006) 1223-U17
    • (2006) Nat. Cell Biology. , vol.8
    • Gavard, J.1    Gutkind, J.S.2
  • 43
    • 0033551899 scopus 로고    scopus 로고
    • Integrin signaling
    • Giancotti F.G., and Ruoslahti E. Integrin signaling. Science 285 (1999) 1028-1033
    • (1999) Science , vol.285 , pp. 1028-1033
    • Giancotti, F.G.1    Ruoslahti, E.2
  • 45
    • 35548936992 scopus 로고    scopus 로고
    • KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions
    • Glading A., Han J., Stockton R.A., and Ginsberg M.H. KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions. J. Cell Biol. 179 (2007) 247-254
    • (2007) J. Cell Biol. , vol.179 , pp. 247-254
    • Glading, A.1    Han, J.2    Stockton, R.A.3    Ginsberg, M.H.4
  • 46
    • 59649096589 scopus 로고    scopus 로고
    • Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke
    • Gore A.V., Lampugnani M.G., Dye L., Dejana E., and Weinstein B.M. Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis. Models Mech. 1 (2008) 275-281
    • (2008) Dis. Models Mech. , vol.1 , pp. 275-281
    • Gore, A.V.1    Lampugnani, M.G.2    Dye, L.3    Dejana, E.4    Weinstein, B.M.5
  • 50
    • 0028947758 scopus 로고
    • Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression
    • Hattori M., Tsukamoto N., Nur-e-Kamal M.S., Rubinfeld B., Iwai K., Kubota H., Maruta H., and Minato N. Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression. Mol. Cell. Biol. 15 (1995) 552-560
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 552-560
    • Hattori, M.1    Tsukamoto, N.2    Nur-e-Kamal, M.S.3    Rubinfeld, B.4    Iwai, K.5    Kubota, H.6    Maruta, H.7    Minato, N.8
  • 52
    • 0032590042 scopus 로고    scopus 로고
    • [Beta]3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
    • Hodivala-Dilke K.M. [Beta]3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J. Clin. Invest. 103 (1999) 229-238
    • (1999) J. Clin. Invest. , vol.103 , pp. 229-238
    • Hodivala-Dilke, K.M.1
  • 54
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: bidirectional, allosteric signaling machines
    • Hynes R.O. Integrins: bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 55
    • 34250702237 scopus 로고    scopus 로고
    • Cell-matrix adhesion in vascular development
    • Hynes R.O. Cell-matrix adhesion in vascular development. J. Thromb. Haemost. 5 (2007) 32-40
    • (2007) J. Thromb. Haemost. , vol.5 , pp. 32-40
    • Hynes, R.O.1
  • 56
    • 0042490495 scopus 로고    scopus 로고
    • RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
    • Katagiri K., Maeda A., Shimonaka M., and Kinashi T. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat. Immunol. 4 (2003) 741-748
    • (2003) Nat. Immunol. , vol.4 , pp. 741-748
    • Katagiri, K.1    Maeda, A.2    Shimonaka, M.3    Kinashi, T.4
  • 57
    • 0034745356 scopus 로고    scopus 로고
    • Rac recruits high-affinity integrin alpha v beta 3 to lamellipodia in endothelial cell migration
    • Kiosses W.B., Shattil S.J., Pampori N., and Schwartz M.A. Rac recruits high-affinity integrin alpha v beta 3 to lamellipodia in endothelial cell migration. Nat. Cell Biol. 3 (2001) 316-320
    • (2001) Nat. Cell Biol. , vol.3 , pp. 316-320
    • Kiosses, W.B.1    Shattil, S.J.2    Pampori, N.3    Schwartz, M.A.4
  • 58
    • 33846847701 scopus 로고    scopus 로고
    • Rap1: a key regulator in cell-cell junction formation
    • Kooistra M.R.H., Dube N., and Bos J.L. Rap1: a key regulator in cell-cell junction formation. J. Cell Sci. 120 (2007) 17-22
    • (2007) J. Cell Sci. , vol.120 , pp. 17-22
    • Kooistra, M.R.H.1    Dube, N.2    Bos, J.L.3
  • 59
    • 0032583125 scopus 로고    scopus 로고
    • Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation
    • Korff T., and Augustin H.G. Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J. Cell Biol. 143 (1998) 1341-1352
    • (1998) J. Cell Biol. , vol.143 , pp. 1341-1352
    • Korff, T.1    Augustin, H.G.2
  • 62
    • 0033520278 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk
    • Larsson H., Klint P., Landgren E., and Claesson-Welsh L. Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk. J. Biol. Chem. 274 (1999) 25726-25734
    • (1999) J. Biol. Chem. , vol.274 , pp. 25726-25734
    • Larsson, H.1    Klint, P.2    Landgren, E.3    Claesson-Welsh, L.4
  • 63
    • 64149100431 scopus 로고    scopus 로고
    • RIAM activates integrins by linking talin to Ras GTPase membrane-targeting sequences
    • Lee H.-S., Lim C.J., Puzon-McLaughlin W., Shattil S.J., and Ginsberg M.H. RIAM activates integrins by linking talin to Ras GTPase membrane-targeting sequences. J. Biol. Chem. 284 (2009) 5119-5127
    • (2009) J. Biol. Chem. , vol.284 , pp. 5119-5127
    • Lee, H.-S.1    Lim, C.J.2    Puzon-McLaughlin, W.3    Shattil, S.J.4    Ginsberg, M.H.5
  • 67
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited
    • Loges S., Mazzone M., Hohensinner P., and Carmeliet P. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell. 15 (2009) 167-170
    • (2009) Cancer Cell. , vol.15 , pp. 167-170
    • Loges, S.1    Mazzone, M.2    Hohensinner, P.3    Carmeliet, P.4
  • 68
    • 42249085404 scopus 로고    scopus 로고
    • cAMP-induced Epac-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics
    • Lyle K.S., Raaijmakers J.H., Bruinsma W., Bos J.L., and de Rooij J. cAMP-induced Epac-Rap activation inhibits epithelial cell migration by modulating focal adhesion and leading edge dynamics. Cell. Signal. 20 (2008) 1104-1116
    • (2008) Cell. Signal. , vol.20 , pp. 1104-1116
    • Lyle, K.S.1    Raaijmakers, J.H.2    Bruinsma, W.3    Bos, J.L.4    de Rooij, J.5
  • 70
  • 71
    • 34748863572 scopus 로고    scopus 로고
    • Mechanisms of integrin vascular endothelial growth factor receptor cross-activation in angiogenesis
    • Mahabeleshwar G.H., Feng W., Reddy K., Plow E.F., and Byzova T.V. Mechanisms of integrin vascular endothelial growth factor receptor cross-activation in angiogenesis. Circ. Res. 101 (2007) 570-580
    • (2007) Circ. Res. , vol.101 , pp. 570-580
    • Mahabeleshwar, G.H.1    Feng, W.2    Reddy, K.3    Plow, E.F.4    Byzova, T.V.5
  • 72
    • 27644580732 scopus 로고    scopus 로고
    • Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton
    • Mei F.C., and Cheng X.D. Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton. Mol. Biosyst. 1 (2005) 325-331
    • (2005) Mol. Biosyst. , vol.1 , pp. 325-331
    • Mei, F.C.1    Cheng, X.D.2
  • 74
    • 0034641614 scopus 로고    scopus 로고
    • Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis
    • Mudgett J.S., Ding J., Guh-Siesel L., Chartrain N.A., Yang L., Gopal S., and Shen M.M. Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. PNAS 97 (2000) 10454-10459
    • (2000) PNAS , vol.97 , pp. 10454-10459
    • Mudgett, J.S.1    Ding, J.2    Guh-Siesel, L.3    Chartrain, N.A.4    Yang, L.5    Gopal, S.6    Shen, M.M.7
  • 75
    • 0036911338 scopus 로고    scopus 로고
    • Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells
    • Nagashima K.I., Endo A., Ogita H., Kawana A., Yamagishi A., Kitabatake A., Matsuda M., and Mochizuki N. Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells. Mol. Biol. Cell. 13 (2002) 4231-4242
    • (2002) Mol. Biol. Cell. , vol.13 , pp. 4231-4242
    • Nagashima, K.I.1    Endo, A.2    Ogita, H.3    Kawana, A.4    Yamagishi, A.5    Kitabatake, A.6    Matsuda, M.7    Mochizuki, N.8
  • 76
    • 77952547316 scopus 로고    scopus 로고
    • Differential regulation of bFGF- and VEGF-Induced angiogenesis in mice lacking junctional adhesion molecule-A
    • Naik M.U., and Naik U.P. Differential regulation of bFGF- and VEGF-Induced angiogenesis in mice lacking junctional adhesion molecule-A. Blood 106 (2005) 533
    • (2005) Blood , vol.106 , pp. 533
    • Naik, M.U.1    Naik, U.P.2
  • 77
    • 33644967620 scopus 로고    scopus 로고
    • Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin alpha(v)beta(3) specific
    • Naik M.U., and Naik U.P. Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin alpha(v)beta(3) specific. J. Cell Sci. 119 (2006) 490-499
    • (2006) J. Cell Sci. , vol.119 , pp. 490-499
    • Naik, M.U.1    Naik, U.P.2
  • 78
    • 0141679018 scopus 로고    scopus 로고
    • Signaling through JAM-1 and alpha(nu)beta(3) is required for the angiogenic action of bFGF: dissociation of the JAM-1 and alpha(nu)beta(3) complex
    • Naik M.U., Mousa S.A., Parkos C.A., and Naik U.P. Signaling through JAM-1 and alpha(nu)beta(3) is required for the angiogenic action of bFGF: dissociation of the JAM-1 and alpha(nu)beta(3) complex. Blood 102 (2003) 2108-2114
    • (2003) Blood , vol.102 , pp. 2108-2114
    • Naik, M.U.1    Mousa, S.A.2    Parkos, C.A.3    Naik, U.P.4
  • 81
    • 33751546663 scopus 로고    scopus 로고
    • Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts
    • Orlova V.V., Economopoulou M., Lupu F., Santoso S., and Chavakis T. Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. J. Exp. Med. 203 (2006) 2703-2714
    • (2006) J. Exp. Med. , vol.203 , pp. 2703-2714
    • Orlova, V.V.1    Economopoulou, M.2    Lupu, F.3    Santoso, S.4    Chavakis, T.5
  • 84
    • 0023721977 scopus 로고
    • Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region
    • 201-4
    • Pizon V., Chardin P., Lerosey I., Olofsson B., and Tavitian A. Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region. Oncogene 3 (1988) 201-4
    • (1988) Oncogene , vol.3
    • Pizon, V.1    Chardin, P.2    Lerosey, I.3    Olofsson, B.4    Tavitian, A.5
  • 85
    • 0023801510 scopus 로고
    • Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B)
    • Pizon V., Lerosey I., Chardin P., and Tavitian A. Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B). Nucleic Acids Res. 16 (1988) 7719
    • (1988) Nucleic Acids Res. , vol.16 , pp. 7719
    • Pizon, V.1    Lerosey, I.2    Chardin, P.3    Tavitian, A.4
  • 86
    • 0025961448 scopus 로고
    • Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells
    • Polakis P.G., Rubinfeld B., Evans T., and McCormick F. Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 239-243
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 239-243
    • Polakis, P.G.1    Rubinfeld, B.2    Evans, T.3    McCormick, F.4
  • 88
    • 34247146472 scopus 로고    scopus 로고
    • Culture of murine aortic explants in 3-dimensional extracellular matrix: a novel, miniaturized assay of angiogenesis in vitro
    • Reed M.J., Karres N., Eyman D., and Vernon R.B. Culture of murine aortic explants in 3-dimensional extracellular matrix: a novel, miniaturized assay of angiogenesis in vitro. Microvasc. Res. 73 (2007) 248-252
    • (2007) Microvasc. Res. , vol.73 , pp. 248-252
    • Reed, M.J.1    Karres, N.2    Eyman, D.3    Vernon, R.B.4
  • 89
    • 33644964291 scopus 로고    scopus 로고
    • Rap1: a turnabout for the crosstalk between cadherins and integrins
    • Retta S.F., Balzac F., and Avolio M. Rap1: a turnabout for the crosstalk between cadherins and integrins. Eur. J. Cell Biol. 85 (2006) 283-293
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 283-293
    • Retta, S.F.1    Balzac, F.2    Avolio, M.3
  • 91
    • 10044256619 scopus 로고    scopus 로고
    • A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters
    • Roberts D.M., Anderson A.L., Hidaka M., Swetenburg R.L., Patterson C., Stanford W.L., and Bautch V.L. A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Mol. Cell. Biol. 24 (2004) 10515-10528
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10515-10528
    • Roberts, D.M.1    Anderson, A.L.2    Hidaka, M.3    Swetenburg, R.L.4    Patterson, C.5    Stanford, W.L.6    Bautch, V.L.7
  • 92
    • 0025940451 scopus 로고
    • Natural history of the cavernous angioma
    • Robinson J.R., Awad I.A., and Little J.R. Natural history of the cavernous angioma. J. Neurosurg. 75 (1991) 709-714
    • (1991) J. Neurosurg. , vol.75 , pp. 709-714
    • Robinson, J.R.1    Awad, I.A.2    Little, J.R.3
  • 93
    • 0030734010 scopus 로고    scopus 로고
    • p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
    • Rousseau S., Houle F., Landry J., and Huota J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15 (1997) 2169-2177
    • (1997) Oncogene , vol.15 , pp. 2169-2177
    • Rousseau, S.1    Houle, F.2    Landry, J.3    Huota, J.4
  • 96
    • 33745863102 scopus 로고    scopus 로고
    • Interaction of Integrin {alpha}vbeta3 with nectin: implication in cross-talk between cell-matrix and cell-cell junctions
    • Sakamoto Y., Ogita H., Hirota T., Kawakatsu T., Fukuyama T., Yasumi M., Kanzaki N., Ozaki M., and Takai Y. Interaction of Integrin {alpha}vbeta3 with nectin: implication in cross-talk between cell-matrix and cell-cell junctions. J. Biol. Chem. 281 (2006) 19631-19644
    • (2006) J. Biol. Chem. , vol.281 , pp. 19631-19644
    • Sakamoto, Y.1    Ogita, H.2    Hirota, T.3    Kawakatsu, T.4    Fukuyama, T.5    Yasumi, M.6    Kanzaki, N.7    Ozaki, M.8    Takai, Y.9
  • 97
    • 38049188053 scopus 로고    scopus 로고
    • Involvement of nectin in inactivation of integrin {alpha}v 3 after the establishment of cell-cell adhesion
    • Sakamoto Y., Ogita H., Komura H., and Takai Y. Involvement of nectin in inactivation of integrin {alpha}v 3 after the establishment of cell-cell adhesion. J. Biol. Chem. 283 (2008) 496-505
    • (2008) J. Biol. Chem. , vol.283 , pp. 496-505
    • Sakamoto, Y.1    Ogita, H.2    Komura, H.3    Takai, Y.4
  • 98
    • 35548989353 scopus 로고    scopus 로고
    • The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors
    • Sakisaka T., Ikeda W., Ogita H., Fujita N., and Takai Y. The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors. Curr. Opin. Cell Biol. 19 (2007) 593-602
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 593-602
    • Sakisaka, T.1    Ikeda, W.2    Ogita, H.3    Fujita, N.4    Takai, Y.5
  • 99
    • 31944446602 scopus 로고    scopus 로고
    • MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion
    • Sakurai A., Fukuhara S., Yamagishi A., Sako K., Kamioka Y., Masuda M., Nakaoka Y., and Mochizuki N. MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion. Mol. Biol. Cell. 17 (2006) 966-976
    • (2006) Mol. Biol. Cell. , vol.17 , pp. 966-976
    • Sakurai, A.1    Fukuhara, S.2    Yamagishi, A.3    Sako, K.4    Kamioka, Y.5    Masuda, M.6    Nakaoka, Y.7    Mochizuki, N.8
  • 100
    • 41649100672 scopus 로고    scopus 로고
    • Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function
    • Sehrawat S., Cullere X., Patel S., Italiano Jr. J., and Mayadas T.N. Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function. Mol. Biol. Cell. 19 (2008) 1261-1270
    • (2008) Mol. Biol. Cell. , vol.19 , pp. 1261-1270
    • Sehrawat, S.1    Cullere, X.2    Patel, S.3    Italiano Jr., J.4    Mayadas, T.N.5
  • 101
    • 0030761145 scopus 로고    scopus 로고
    • Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22
    • Serebriiskii I., Estojak J., Sonoda G., Testa J.R., and Golemis E.A. Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22. Oncogene 15 (1997) 1043-1049
    • (1997) Oncogene , vol.15 , pp. 1043-1049
    • Serebriiskii, I.1    Estojak, J.2    Sonoda, G.3    Testa, J.R.4    Golemis, E.A.5
  • 102
    • 65249125248 scopus 로고    scopus 로고
    • Junctional adhesion molecule a interacts with afadin and PDZ-GEF2 to activate Rap1A, regulate beta 1 integrin levels, and enhance cell migration
    • Severson E.A., Lee W.Y., Capaldo C.T., Nusrat A., and Parkos C.A. Junctional adhesion molecule a interacts with afadin and PDZ-GEF2 to activate Rap1A, regulate beta 1 integrin levels, and enhance cell migration. Mol. Biol. Cell. 20 (2009) 1916-1925
    • (2009) Mol. Biol. Cell. , vol.20 , pp. 1916-1925
    • Severson, E.A.1    Lee, W.Y.2    Capaldo, C.T.3    Nusrat, A.4    Parkos, C.A.5
  • 104
    • 0034608787 scopus 로고    scopus 로고
    • Focal adhesion kinase, Rap1, and transcriptional induction of vascular endothelial growth factor
    • Sheta E.A., Harding M.A., Conaway M.R., and Theodorescu D. Focal adhesion kinase, Rap1, and transcriptional induction of vascular endothelial growth factor. J. Natl. Cancer Inst. 92 (2000) 1065-1073
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1065-1073
    • Sheta, E.A.1    Harding, M.A.2    Conaway, M.R.3    Theodorescu, D.4
  • 107
    • 67650770190 scopus 로고    scopus 로고
    • Cooperation between integrin alpha(V)beta(3) and VEGFR2 in angiogenesis
    • Somanath P.R., Malinin N.L., and Byzova T.V. Cooperation between integrin alpha(V)beta(3) and VEGFR2 in angiogenesis. Angiogenesis 12 (2009) 177-185
    • (2009) Angiogenesis , vol.12 , pp. 177-185
    • Somanath, P.R.1    Malinin, N.L.2    Byzova, T.V.3
  • 108
    • 0028979153 scopus 로고
    • Deletion of [beta]1 integrins in mice results in inner cell mass failure and peri-implantation lethality
    • Stephens L.E. Deletion of [beta]1 integrins in mice results in inner cell mass failure and peri-implantation lethality. Genes Dev. 9 (1995) 1883-1895
    • (1995) Genes Dev. , vol.9 , pp. 1883-1895
    • Stephens, L.E.1
  • 109
    • 2942678693 scopus 로고    scopus 로고
    • Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation
    • Stoletov K.V., and Terman B.I. Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation. Biochem. Biophys. Res. Commun. 320 (2004) 70-75
    • (2004) Biochem. Biophys. Res. Commun. , vol.320 , pp. 70-75
    • Stoletov, K.V.1    Terman, B.I.2
  • 110
    • 1642635123 scopus 로고    scopus 로고
    • Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation
    • Stoletov K.V., Gong C.H., and Terman B.I. Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation. Exp. Cell Res. 295 (2004) 258-268
    • (2004) Exp. Cell Res. , vol.295 , pp. 258-268
    • Stoletov, K.V.1    Gong, C.H.2    Terman, B.I.3
  • 111
    • 0038741814 scopus 로고    scopus 로고
    • Does Rap1 deserve a bad Rap?
    • Stork P.J. Does Rap1 deserve a bad Rap?. Trends Biochem. Sci. 28 (2003) 267-275
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 267-275
    • Stork, P.J.1
  • 112
    • 0030038229 scopus 로고    scopus 로고
    • Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
    • Stromblad S., Becker J.C., Yebra M., Brooks P.C., and Cheresh D.A. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. J. Clin. Invest. 98 (1996) 426-433
    • (1996) J. Clin. Invest. , vol.98 , pp. 426-433
    • Stromblad, S.1    Becker, J.C.2    Yebra, M.3    Brooks, P.C.4    Cheresh, D.A.5
  • 113
    • 0033118228 scopus 로고    scopus 로고
    • VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
    • Takahashi T., Ueno H., and Shibuya M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 18 (1999) 2221-2230
    • (1999) Oncogene , vol.18 , pp. 2221-2230
    • Takahashi, T.1    Ueno, H.2    Shibuya, M.3
  • 115
    • 38149004289 scopus 로고    scopus 로고
    • Beta 1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis
    • Tanjore H., Zeisberg E.M., Gerami-Naini B., and Kalluri R. Beta 1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis. Dev. Dyn. 237 (2008) 75-82
    • (2008) Dev. Dyn. , vol.237 , pp. 75-82
    • Tanjore, H.1    Zeisberg, E.M.2    Gerami-Naini, B.3    Kalluri, R.4
  • 116
    • 33344467865 scopus 로고    scopus 로고
    • Angiogenesis in the mouse retina: a model system for experimental manipulation
    • Uemura A., Kusuhara S., Katsuta H., and Nishikawa S.-I. Angiogenesis in the mouse retina: a model system for experimental manipulation. Exp. Cell Res. 312 (2006) 676-683
    • (2006) Exp. Cell Res. , vol.312 , pp. 676-683
    • Uemura, A.1    Kusuhara, S.2    Katsuta, H.3    Nishikawa, S.-I.4
  • 117
    • 38549128935 scopus 로고    scopus 로고
    • VE-cadherin - the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • Vestweber D. VE-cadherin - the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscl. Thromb. Vasc. Biol. 28 (2008) 223-232
    • (2008) Arterioscl. Thromb. Vasc. Biol. , vol.28 , pp. 223-232
    • Vestweber, D.1
  • 118
    • 0037262297 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation
    • Voss A.K., Gruss P., and Thomas T. The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation. Development 130 (2003) 355-367
    • (2003) Development , vol.130 , pp. 355-367
    • Voss, A.K.1    Gruss, P.2    Thomas, T.3
  • 119
    • 39849104321 scopus 로고    scopus 로고
    • Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis
    • Wallez Y., and Huber P. Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim. Biophys. Acta-Biomembr. 1778 (2008) 794-809
    • (2008) Biochim. Biophys. Acta-Biomembr. , vol.1778 , pp. 794-809
    • Wallez, Y.1    Huber, P.2
  • 120
    • 33644765206 scopus 로고    scopus 로고
    • Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation
    • Wang Z., Dillon T.J., Pokala V., Mishra S., Labudda K., Hunter B., and Stork P.J.S. Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation. Mol. Cell. Biol. 26 (2006) 2130-2145
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2130-2145
    • Wang, Z.1    Dillon, T.J.2    Pokala, V.3    Mishra, S.4    Labudda, K.5    Hunter, B.6    Stork, P.J.S.7
  • 122
    • 7244247062 scopus 로고    scopus 로고
    • Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis
    • Weis S., Cui J., Barnes L., and Cheresh D. Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. J. Cell Biol. 167 (2004) 223-229
    • (2004) J. Cell Biol. , vol.167 , pp. 223-229
    • Weis, S.1    Cui, J.2    Barnes, L.3    Cheresh, D.4
  • 124
    • 1842559498 scopus 로고    scopus 로고
    • Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations
    • Whitehead K.J., Plummer N.W., Adams J.A., Marchuk D.A., and Li D.Y. Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations. Development 131 (2004) 1437-1448
    • (2004) Development , vol.131 , pp. 1437-1448
    • Whitehead, K.J.1    Plummer, N.W.2    Adams, J.A.3    Marchuk, D.A.4    Li, D.Y.5
  • 126
    • 51349163548 scopus 로고    scopus 로고
    • Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions
    • Yan J.L., Li F., Ingram D.A., and Quilliam L.A. Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Mol. Cell. Biol. 28 (2008) 5803-5810
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5803-5810
    • Yan, J.L.1    Li, F.2    Ingram, D.A.3    Quilliam, L.A.4
  • 127
    • 0027371908 scopus 로고
    • Embryonic mesodermal defects in [alpha]5 integrin-deficient mice
    • Yang J.T., Rayburn H., and Hynes R.O. Embryonic mesodermal defects in [alpha]5 integrin-deficient mice. Development 119 (1993) 1093-1105
    • (1993) Development , vol.119 , pp. 1093-1105
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3
  • 128
    • 0035895711 scopus 로고    scopus 로고
    • Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
    • Zachary I., and Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc. Res. 49 (2001) 568-581
    • (2001) Cardiovasc. Res. , vol.49 , pp. 568-581
    • Zachary, I.1    Gliki, G.2
  • 129
    • 0037084658 scopus 로고    scopus 로고
    • KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis
    • Zawistowski J.S., Serebriiskii I.G., Lee M.F., Golemis E.A., and Marchuk D.A. KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. Human Mol. Genet. 11 (2002) 389-396
    • (2002) Human Mol. Genet. , vol.11 , pp. 389-396
    • Zawistowski, J.S.1    Serebriiskii, I.G.2    Lee, M.F.3    Golemis, E.A.4    Marchuk, D.A.5
  • 130
    • 0035542933 scopus 로고    scopus 로고
    • Interaction between krit1 and icap1 alpha infers perturbation of integrin beta 1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation
    • Zhang J., Clatterbuck R.E., Rigamonti D., Chang D.D., and Dietz H.C. Interaction between krit1 and icap1 alpha infers perturbation of integrin beta 1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation. Human Mol. Genet. 10 (2001) 2953-2960
    • (2001) Human Mol. Genet. , vol.10 , pp. 2953-2960
    • Zhang, J.1    Clatterbuck, R.E.2    Rigamonti, D.3    Chang, D.D.4    Dietz, H.C.5
  • 131
    • 65849527175 scopus 로고    scopus 로고
    • Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation
    • Zhang J., Basu S., Rigamonti D., Dietz H.C., and Clatterbuck R.E. Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation. Neurosurgery 63 (2008) 571-578
    • (2008) Neurosurgery , vol.63 , pp. 571-578
    • Zhang, J.1    Basu, S.2    Rigamonti, D.3    Dietz, H.C.4    Clatterbuck, R.E.5
  • 132
    • 0036941837 scopus 로고    scopus 로고
    • The thin prep rat aortic ring assay: a modified method for the characterization of angiogenesis in whole mounts
    • Zhu W.-H., and Nicosia R. The thin prep rat aortic ring assay: a modified method for the characterization of angiogenesis in whole mounts. Angiogenesis 5 (2002) 81-86
    • (2002) Angiogenesis , vol.5 , pp. 81-86
    • Zhu, W.-H.1    Nicosia, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.