Ccm1 is required for arterial morphogenesis: Implications for the etiology of human cavernous malformations

Development

Volumn 131, Issue 6, 2004, Pages 1437-1448

  Whitehead, Kevin J ^a,b   Plummer, Nicholas W ^c   Adams, Jennifer A ^a   Marchuk, Douglas A ^c   Li, Dean Y ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Ccm1; Efnb2; Epilepsy; Gene targeting; Mice; Notch; Stroke

Indexed keywords

BIOLOGICAL MARKER; CELL PROTEIN; CEREBRAL CAVERNOUS MALFORMATION PROTEIN 1; PROTEIN CCM1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; BRAIN HEMORRHAGE; BRANCHIAL ARCH; CELL PROLIFERATION; CEREBROVASCULAR MALFORMATION; DISEASE ASSOCIATION; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; FREQUENCY ANALYSIS; GENE EXPRESSION; GENE MUTATION; HOMOZYGOSITY; HUMAN; MORBIDITY; MORTALITY; MOUSE; NERVE CELL LESION; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; STROKE;

ANIMALS; ARTERIES; HEART; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH;

ANIMALIA; MURINAE;

EID: 1842559498     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01036     Document Type: Review

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