Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1

Journal of Biological Chemistry

Volumn 282, Issue 27, 2007, Pages 19781-19787

  Hong, Jia ^a,b   Doebele, Robert C ^b   Lingen, Mark W ^b   Quilliam, Lawrence A ^c   Tang, Wei Jen ^a   Rosner, Marsha Rich ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; CHEMOTAXIS; EDEMA TOXIN (ET);

CELL PROLIFERATION; ENDOTHELIAL CELLS; ENZYME ACTIVITY; NUCLEOTIDES; TUMORS;

TOXIC MATERIALS;

ADENYLATE CYCLASE; ANTHRAX EDEMA TOXIN; CYCLIC AMP; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN EPAC; PROTEIN EPAC2; RAP1 PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ADENYLATE CYCLASE; BACTERIAL PROTEINS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOTAXIS; CYCLIC AMP; CYTOSKELETON; ENDOTHELIAL CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RECEPTORS, PEPTIDE; SIGNAL TRANSDUCTION; TELOMERE-BINDING PROTEINS;

EID: 34547127183     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700128200     Document Type: Article

References (39)

1. Gupta, K., and Zhang, J. (2005) Postgrad. Med. J. 81, 236-242
2. Leppla, S. H. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 3162-3166
3. Klimpel, K. R., Arora, N., and Leppla, S. H. (1994) Mol. Microbiol. 13, 1093-1100
4. Duesbery, N. S., Webb, C. P., Leppla, S. H., Gordon, V. M., Klimpel, K. R., Copeland, T. D., Ahn, N. G., Oskarsson, M. K., Fukasawa, K., Paull, K. D., and Vande Woude, G. F. (1998) Science 280, 734-737
5. Vitale, G., Pellizzari, R., Recchi, C., Napolitani, G., Mock, M., and Montecucco, C. (1998) Biochem. Biophys. Res. Commun. 248, 706-711
6. Bradley, K. A., Mogridge, J., Mourez, M., Collier, R. J., and Young, J. A. (2001) Nature 414, 225-229
7. Scobie, H. M., Rainey, G. J., Bradley, K. A., and Young, J. A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 5170-5174
8. Santelli, E., Bankston, L. A., Leppla, S. H., and Liddington, R. C. (2004) Nature 430, 905-908
9. Duesbery, N. S., Resau, J., Webb, C. P., Koochekpour, S., Koo, H. M., Leppla, S. H., and Vande Woude, G. F. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4089-4094
10. Kirby, J. E. (2004) Infect. Immun. 72, 430-439
11. de Rooij, J., Zwartkruis, F. J., Verheijen, M. H., Cool, R. H., Nijman, S. M., Wittinghofer, A., and Bos, J. L. (1998) Nature 396, 474-477
12. Quilliam, L. A., Rebhun, J. F., and Castro, A. F. (2002) Prog. Nucleic Acid Res. Mol. Biol. 71, 391-444
13. Bos, J. L. (2005) Curr. Opin. Cell Biol. 17, 123-128
14. Soelaiman, S., Wei, B. Q., Bergson, P., Lee, Y. S., Shen, Y., Mrksich, M., Shoichet, B. K., and Tang, W. J. (2003) J. Biol. Chem. 278, 25990-25997
15. Cline, E. I., Bicciato, S., DiBello, C., and Lingen, M. W. (2002) Cancer Res. 62, 7143-7148
16. Khodarev, N. N., Yu, J., Labay, E., Darga, T., Brown, C. K., Mauceri, H. J., Yassari, R., Gupta, N., and Weichselbaum, R. R. (2003) J. Cell Sci. 116, 1013-1022
17. Li, L., Okura, M., and Imamoto, A. (2002) Mol. Cell. Biol. 22, 1203-1217
18. Reinhart-King, C. A., Dembo, M., and Hammer, D. A. (2005) Biophys. J. 89, 676-689
19. Lingen, M. W. (2003) Methods Mol. Med. 78, 337-347
20. Arthur, W. T., Quilliam, L. A., and Cooper, J. A. (2004) J. Cell Biol. 167, 111-122
21. Naldini, L., Blomer, U., Gage, F. H., Trono, D., and Verma, I. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11382-11388
22. Kuo, W. L., Duke, C. J., Abe, M. K., Kaplan, E. L., Gomes, S., and Rosner, M. R. (2004) J. Biol. Chem. 279, 23073-23081
23. Cullere, X., Shaw, S. K., Andersson, L., Hirahashi, J., Luscinskas, F. W., and Mayadas, T. N. (2005) Blood 105, 1950-1955
24. Ribatti, D. (2005) Br. J. Haematol. 128, 303-309
25. de Rooij, J., Rehmann, H., van Triest, M., Cool, R. H., Wittinghofer, A., and Bos, J. L. (2000) J. Biol. Chem. 275, 20829-20836
26. Ichiba, T., Hoshi, Y., Eto, Y., Tajima, N., and Kuraishi, Y. (1999) FEBS Lett. 457, 85-89
27. Rebhun, J. F., Castro, A. F., and Quilliam, L. A. (2000) J. Biol. Chem. 275, 34901-34908
28. Enserink, J. M., Christensen, A. E., de Rooij, J., van Triest, M., Schwede, F., Genieser, H. G., Doskeland, S. O., Blank, J. L., and Bos, J. L. (2002) Nat. Cell Biol. 4, 901-906
29. Rehmann, H., Schwede, F., Doskeland, S. O., Wittinghofer, A., and Bos, J. L. (2003) J. Biol. Chem. 278, 38548-38556
30. Davies, S. P., Reddy, H., Caivano, M., and Cohen, P. (2000) Biochem. J. 351, 95-105
31. Fukuhara, S., Sakurai, A., Sano, H., Yamagishi, A., Somekawa, S., Takakura, N., Saito, Y., Kangawa, K., and Mochizuki, N. (2005) Mol. Cell. Biol. 25, 136-146
32. Volpert, O. V. (2000) Cancer Metastasis Rev. 19, 87-92
33. Nor, J. E., Mitra, R. S., Sutorik, M. M., Mooney, D. J., Castle, V. P., and Polverini, P. J. (2000) J. Vasc. Res. 37, 209-218
34. Dodge-Kafka, K. L., Soughayer, J., Pare, G. C., Carlisle Michel, J. J., Langeberg, L. K., Kapiloff, M. S., and Scott, J. D. (2005) Nature 437, 574-578
35. Li, Y., Asuri, S., Rebhun, J. F., Castro, A. F., Paranavitana, N. C., and Quilliam, L. A. (2006) J. Biol. Chem. 281, 2506-2514
36. Wang, Z., Dillon, T. J., Pokala, V., Mishra, S., Labudda, K., Hunter, B., and Stork, P. J. (2006) Mol. Cell. Biol. 26, 2130-2145
37. Hong, J., Beeler, J., Zhukovskaya, N. L., He, W., Tang, W. J., and Rosner, M. R. (2005) Biochem. Biophys. Res. Commun. 335, 850-857
38. Wittchen, E. S., Worthylake, R. A., Kelly, P., Casey, P. J., Quilliam, L. A., and Burridge, K. (2005) J. Biol. Chem. 280, 11675-11682
39. Hoover, D. L., Friedlander, A. M., Rogers, L. C., Yoon, I. K., Warren, R. L., and Cross, A. S. (1994) Infect. Immun. 62, 4432-4439