Diverse effects of vascular endothelial growth factor on human pulmonary endothelial barrier and migration

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 291, Issue 4, 2006, Pages

  Mirzapoiazova, T ^a   Kolosova, I ^a   Usatyuk, P V ^a   Natarajan, V ^a   Verin, A D ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b CIS Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FOCAL ADHESION KINASE; MYOSIN LIGHT CHAIN; VASCULOTROPIN;

ARTICLE; CALCIUM CELL LEVEL; CELL JUNCTION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY;

ADHERENS JUNCTIONS; CALCIUM; CAPILLARY PERMEABILITY; CELL MOVEMENT; CELLS, CULTURED; CYCLIC AMP; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INTRACELLULAR MEMBRANES; MYOSIN LIGHT CHAINS; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PULMONARY ARTERY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33749355470     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00014.2006     Document Type: Article

References (46)

1. Abadie Y, Bregeon F, Papazian L, Lange F, Chailley-Heu B, Thomas P, Duvaldestin P, Adnot S, Maitre B, and Delclaux C. Decreased VEGF concentration in lung tissue and vascular injury during ARDS. Eur Respir J 25: 139-146, 2005.
2. Abedi H and Zachary I. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells. J Biol Chem 272: 15442-15451, 1997.
3. Avraham HK, Lee TH, Koh Y, Kim TA, Jiang S, Sussman M, Samarel AM, and Avraham S. Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase. J Biol Chem 278: 36661-36668, 2003.
4. Becker PM, Verin AD, Booth MA, Liu F, Birukova A, and Garcia JG. Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 281: L1500-L1511, 2001.
5. Berg JT, Fu Z, Breen EC, Tran HC, Mathieu-Costello O, and West JB. High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma. J Appl Physiol 83: 120-128, 1997.
6. Berse B, Brown LF, Van de Water L, Dvorak HF, and Senger DR. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 3: 211-220, 1992.
7. Breslin JW, Pappas PJ, Cerveira JJ, Hobson RW 2nd, and Duran WN. VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide. Am J Physiol Heart Circ Physiol 284: H92-H100, 2003.
8. 2+ and von Willebrand factor release in human endothelial cells. Am J Pathol 138: 213-221, 1991.
9. Chang Y, Munn L, Hillsley M, Dull R, Yuan J, Lakshiminarayanan S, Gardner T, Jain R, and Tarbell J. Effect of vascular endothelial growth factor on cultured endothelial cell monolayer transport properties. Microvasc Res 59: 265-277, 2000.
10. Cohen A, Carbajal J, and Schaefer RC. VEGF stimulates tyrosine phosphorylation of B-catenin and small-pore endothelial barrier dysfunction. Am J Physiol Heart Circ Physiol 277: H2038-H2049, 1999.
11. Corne J, Chupp G, Lee CG, Homer RJ, Zhu Z, Chen Q, Ma B, Du Y, Roux F, McArdle J, Waxman AB, and Elias JA. IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. J Clin Invest 106: 783-791, 2000.
12. Dudek SM and Garcia JG. Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol 91: 1487-1500, 2001.
13. Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25: 581-611, 2004.
14. Garcia JG, Davis HW, and Patterson CE. Regulation of endothelial gap formation and barrier dysfunction: role of myosin light chain phosphorylation. J Cell Physiol 163: 510-522, 1995.
15. Garcia JG, Schaphorst KL, Shi S, Verin AD, Hart CM, Callahan KS, and Patterson CE. Mechanisms of ionomycin-induced endothelial cell barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 273: L172-L184, 1997.
16. Giaever I and Keese CR. A morphological biosensor for mammalian cells. Nature 366: 591-592, 1993.
17. Gurkan OU, O'Donnell C, Brower R, Ruckdeschel E, and Becker PM. Differential effects of mechanical ventilatory strategy on lung injury and systemic organ inflammation in mice. Am J Physiol Lung Cell Mol Physiol 285: L710-L718, 2003.
18. Hanks SK, Ryzhova L, Shin NY, and Brabek J. Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility. Front Biosci 8: d982-d996, 2003.
19. Hippenstiel S, Krull M, Ikemann A, Risau W, Clauss M, and Suttorp N. VEGF induces hyperpermeability by a direct action on endothelial cells. Am J Physiol Lung Cell Mol Physiol 274: L678-L684, 1998.
20. Kaner RJ and Crystal RG. Compartmentalization of vascular endothelial growth factor to the epithelial surface of the human lung. Mol Med 7: 240-246, 2001.
21. Kaner RJ, Ladetto JV, Singh R, Fukuda N, Matthay MA, and Crystal RG. Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. Am J Respir Cell Mol Biol 22: 657-664, 2000.
22. Karmpaliotis D, Kosmidou I, Ingenito EP, Hong K, Malhotra A, Sunday ME, and Haley KJ. Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol 283: L585-L595, 2002.
23. Kazi AA, Lee WS, Wagner E, and Becker PM. VEGF, fetal liver kinase-1, and permeability increase during unilateral lung ischemia. Am J Physiol Lung Cell Mol Physiol 279: L460-L467, 2000.
24. Kevil CG, Payne DK, Mire E, and Alexander JS. Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J Biol Chem 273: 15099-15103, 1998.
25. Lal BK, Varma S, Pappas PJ, Hobson RW 2nd, and Duran WN. VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 62: 252-262, 2001.
26. Maitre B, Boussat S, Jean D, Gouge M, Brochard L, Housset B, Adnot S, and Delclaux C. Vascular endothelial growth factor synthesis in the acute phase of experimental and clinical lung injury. Eur Respir J 18: 100-106, 2001.
27. Maniscalco WM, Watkins RH, Finkelstein JN, and Campbell MH. Vascular endothelial growth factor mRNA increases in alveolar epithelial cells during recovery from oxygen injury. Am J Respir Cell Mol Biol 13: 377-386, 1995.
28. Mirzapoiazova T, Kolosova IA, Romer L, Garcia JG, and Verin AD. The role of caldesmon in the regulation of endothelial cytoskeleton and migration. J Cell Physiol 203: 520-528, 2005.
29. Monaccii WT, Merrill MJ, and Oldfield EH. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am J Physiol Cell Physiol 264: C955-C1002, 1993.
30. Moore TM, Norwood NR, Creighton JR, Babal P, Brough GH, Shasby DM, and Stevens T. Receptor-dependent activation of store-operated calcium entry increases endothelial cell permeability. Am J Physiol Lung Cell Mol Physiol 279: L691-L698, 2000.
31. Mura M, dos Santos CC, Stewart D, and Liu M. Vascular endothelial growth factor and related molecules in acute lung injury. J Appl Physiol 97: 1605-1617, 2004.
32. Roberts WG and Palade GE. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 108: 2369-2379, 1995.
33. Schlaepfer DD, Hauck CR, and Sieg DJ. Signaling through focal adhesion kinase. Prog Biophys Mol Biol 71: 435-478, 1999.
34. Shikata Y, Birukov KG, Birukova AA, Verin A, and Garcia JG. Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate-and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J 17: 2240-2249, 2003.
35. Senger DR, Galli SJ, Dvorak AM, Peruzzi CA, Harvey VS, and Dvorak HF. Tumor cells secrete vascular permeability factor that promotes accumulation of ascites fluid. Science 219: 983-985, 1983.
36. Shifren JL, Doldi N, Ferrara N, Mesiano S, and Jaffe RB. In the human fetus, vascular endothelial growth factor is expressed in epithelial cells and myocytes, but not vascular endothelium: implications for mode of action. J Clin Endocrinol Metab 79: 316-322, 1994.
37. Sirois MG and Edelman ER. VEGF effect on vascular permeability is mediated by synthesis of platelet-activating factor. Am J Physiol Heart Circ Physiol 272: H2746-H2756, 1997.
38. Song CJ, Hrnjez BJ, Farokhzad OC, and Matthews JB. PKC-regulates basolateral endocytosis in human T84 intestinal epithelia: role of F-actin and MARCKS. Am J Physiol Cell Physiol 277: C1239-C1249, 1999.
39. Thickett DR, Armstrong L, Christie SJ, and Millar AB. Vascular endothelial growth factor may contribute to increased vascular permeability in acute respiratory distress syndrome. Am J Respir Crit Care Med 164: 1601-1605, 2001.
40. Thickett DR, Armstrong L, and Millar AB. A role for vascular endothelial growth factor in acute and resolving lung injury. Am J Respir Crit Care Med 166: 1332-1337, 2002.
41. Tiruppathi C, Malik AB, Del Vecchio PJ, Keese CR, and Giaever I. Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proc Natl Acad Sci USA 89: 7919-7923, 1992.
42. 2+ in diperoxovanadate-induced cytoskeletal remodeling and endothelial cell barrier function. Am J Physiol Lung Cell Mol Physiol 285: L1006-L1017, 2003.
43. van Nieuw Amerongen GP, Draijer R, Vermeer MA, and van Hinsbergh VW. Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA. Circ Res 83: 1115-1123, 1998.
44. van Nieuw Amerongen GP and van Hinsbergh VW. Targets for pharmacological intervention of endothelial hyperpermeability and barrier function. Vascul Pharmacol 39: 257-272, 2002.
45. Wang W, Dentler WL, and Borchardt RT. VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly. Am J Physiol Heart Circ Physiol 280: H434-H440, 2001.
46. Zachary I and Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 49: 568-581, 2001.