메뉴 건너뛰기




Volumn 123, Issue 10, 2010, Pages 1693-1704

Telomeric function of mammalian telomerases at short telomeres

Author keywords

ALT; Telomerase activity; Telomerase processivity; Telomere maintenance

Indexed keywords

TELOMERASE; DNA; TERT PROTEIN, HUMAN; TERT PROTEIN, MOUSE;

EID: 77952415874     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.063636     Document Type: Article
Times cited : (15)

References (70)
  • 1
    • 0034775749 scopus 로고    scopus 로고
    • N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo
    • Armbruster, B. N., Banik, S. S., Guo, C., Smith, A. C. and Counter, C. M. (2001). N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo. Mol. Cell. Biol. 21, 7775-7786.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7775-7786
    • Armbruster, B.N.1    Banik, S.S.2    Guo, C.3    Smith, A.C.4    Counter, C.M.5
  • 2
    • 0037404425 scopus 로고    scopus 로고
    • Putative telomere-recruiting domain in the catalytic subunit of human telomerase
    • Armbruster, B. N., Etheridge, K. T., Broccoli, D. and Counter, C. M. (2003). Putative telomere-recruiting domain in the catalytic subunit of human telomerase. Mol. Cell. Biol. 23, 3237-3246.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3237-3246
    • Armbruster, B.N.1    Etheridge, K.T.2    Broccoli, D.3    Counter, C.M.4
  • 3
    • 0029128539 scopus 로고
    • Boundary elements of the Tetrahymena telomerase RNA template and alignment domains
    • Autexier, C. and Greider, C. W. (1995). Boundary elements of the Tetrahymena telomerase RNA template and alignment domains. Genes Dev. 15, 2227-2239.
    • (1995) Genes Dev. , vol.15 , pp. 2227-2239
    • Autexier, C.1    Greider, C.W.2
  • 4
    • 33745849998 scopus 로고    scopus 로고
    • The structure and function of telomerase reverse transcriptase
    • DOI 10.1146/annurev.biochem.75.103004.142412
    • Autexier, C. and Lue, N. F. (2006). The structure and function of telomerase reverse transcriptase. Annu. Rev. Biochem. 75, 493-517. (Pubitemid 44118041)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 493-517
    • Autexier, C.1    Lue, N.F.2
  • 5
    • 0029958047 scopus 로고    scopus 로고
    • Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA
    • Autexier, C., Pruzan, R., Funk, W. D. and Greider, C. W. (1996). Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. EMBO J. 15, 5928-5935.
    • (1996) EMBO J. , vol.15 , pp. 5928-5935
    • Autexier, C.1    Pruzan, R.2    Funk, W.D.3    Greider, C.W.4
  • 7
    • 0032576733 scopus 로고    scopus 로고
    • Reconstitution of human telomerase activity in vitro
    • Beattie, T. L., Zhou, W., Robinson, M. O. and Harrington, L. (1998). Reconstitution of human telomerase activity in vitro. Curr. Biol. 8, 177-180. (Pubitemid 28091578)
    • (1998) Current Biology , vol.8 , Issue.3 , pp. 177-180
    • Beattie, T.L.1    Zhou, W.2    Robinson, M.O.3    Harrington, L.4
  • 8
    • 0033790120 scopus 로고    scopus 로고
    • Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding
    • Beattie, T. L., Zhou, W., Robinson, M. O. and Harrington, L. (2000). Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding. Mol. Biol. Cell 11, 3329-3340.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 3329-3340
    • Beattie, T.L.1    Zhou, W.2    Robinson, M.O.3    Harrington, L.4
  • 9
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco, M., Funk, W., Villeponteau, B. and Greider, C. W. (1995). Functional characterization and developmental regulation of mouse telomerase RNA. Science 269, 1267-1270.
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 12
    • 22544450728 scopus 로고    scopus 로고
    • Transformation of human and murine fibroblasts without viral oncoproteins
    • Boehm, J. S., Hession, M. T., Bulmer, S. E. and Hahn, W. C. (2005). Transformation of human and murine fibroblasts without viral oncoproteins. Mol. Cell. Biol. 25, 6464-6474.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 6464-6474
    • Boehm, J.S.1    Hession, M.T.2    Bulmer, S.E.3    Hahn, W.C.4
  • 13
    • 0035444984 scopus 로고    scopus 로고
    • Telomere maintenance by telomerase and by recombination can coexist in human cells
    • Cerone, M. A., Londono-Vallejo, J. A. and Bacchetti, S. (2001). Telomere maintenance by telomerase and by recombination can coexist in human cells. Hum. Mol. Genet. 10, 1945-1952.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1945-1952
    • Cerone, M.A.1    Londono-Vallejo, J.A.2    Bacchetti, S.3
  • 14
    • 33845231392 scopus 로고    scopus 로고
    • Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance
    • Cerone, M. A., Londono-Vallejo, J. A. and Autexier, C. (2006). Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance. Oncogene 25, 7411-7420.
    • (2006) Oncogene , vol.25 , pp. 7411-7420
    • Cerone, M.A.1    Londono-Vallejo, J.A.2    Autexier, C.3
  • 15
    • 0037439107 scopus 로고    scopus 로고
    • Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
    • Chen, J. L. and Greider, C. W. (2003). Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. EMBO J. 22, 304-314.
    • (2003) EMBO J. , vol.22 , pp. 304-314
    • Chen, J.L.1    Greider, C.W.2
  • 16
    • 34147095342 scopus 로고    scopus 로고
    • Protein composition of catalytically active human telomerase from immortal cells
    • Cohen, S. B., Graham, M. E., Lovrecz, G. O., Bache, N., Robinson, P. J. and Reddel, R. R. (2007). Protein composition of catalytically active human telomerase from immortal cells. Science 315, 1850-1853.
    • (2007) Science , vol.315 , pp. 1850-1853
    • Cohen, S.B.1    Graham, M.E.2    Lovrecz, G.O.3    Bache, N.4    Robinson, P.J.5    Reddel, R.R.6
  • 18
    • 0032485416 scopus 로고    scopus 로고
    • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
    • Counter, C. M., Meyerson, M., Eaton, E. N., Ellisen, L. W., Dickinson Caddle, S., Haber, D. A. and Weinberg, R. A. (1998b). Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene 16, 1217-1222. (Pubitemid 28127521)
    • (1998) Oncogene , vol.16 , Issue.9 , pp. 1217-1222
    • Counter, C.M.1    Meyerson, M.2    Eaton, E.N.3    Ellisen, L.W.4    Caddle, S.D.5    Haber, D.A.6    Weinberg, R.A.7
  • 22
  • 24
    • 0038392866 scopus 로고    scopus 로고
    • Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs
    • DOI 10.1016/S1097-2765(03)00196-5
    • Fu, D. and Collins, K. (2003). Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs. Mol. Cell 11, 1361-1372. (Pubitemid 36645153)
    • (2003) Molecular Cell , vol.11 , Issue.5 , pp. 1361-1372
    • Fu, D.1    Collins, K.2
  • 25
    • 33746922335 scopus 로고    scopus 로고
    • Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase
    • Garforth, S. J., Wu, Y. Y. and Prasad, V. R. (2006). Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase. Biochem. J. 397, 399-406.
    • (2006) Biochem. J. , vol.397 , pp. 399-406
    • Garforth, S.J.1    Wu, Y.Y.2    Prasad, V.R.3
  • 26
    • 0037109212 scopus 로고    scopus 로고
    • Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro
    • Gavory, G., Farrow, M. and Balasubramanian, S. (2002). Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. Nucleic Acids Res. 30, 4470-4480.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4470-4480
    • Gavory, G.1    Farrow, M.2    Balasubramanian, S.3
  • 27
    • 0032473931 scopus 로고    scopus 로고
    • Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation
    • Greenberg, R. A., Allsopp, R. C., Chin, L., Morin, G. B. and DePinho, R. A. (1998). Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 16, 1723-1730.
    • (1998) Oncogene , vol.16 , pp. 1723-1730
    • Greenberg, R.A.1    Allsopp, R.C.2    Chin, L.3    Morin, G.B.4    Depinho, R.A.5
  • 28
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider, C. W. and Blackburn, E. H. (1989). A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337.
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 29
    • 0035445809 scopus 로고    scopus 로고
    • Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway
    • Grobelny, J. V., Kulp-McEliece, M. and Broccoli, D. (2001). Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway. Hum. Mol. Genet. 10, 1953-1961.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1953-1961
    • Grobelny, J.V.1    Kulp-McEliece, M.2    Broccoli, D.3
  • 30
    • 0035825601 scopus 로고    scopus 로고
    • Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability
    • DOI 10.1038/sj.onc.1204145
    • Guiducci, C., Cerone, M. A. and Bacchetti, S. (2001). Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability. Oncogene 20, 714-725. (Pubitemid 32179340)
    • (2001) Oncogene , vol.20 , Issue.6 , pp. 714-725
    • Guiducci, C.1    Cerone, M.A.2    Bacchetti, S.3
  • 31
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • Harley, C. B. (2008). Telomerase and cancer therapeutics. Nat. Rev. Cancer 8, 167-179.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 167-179
    • Harley, C.B.1
  • 32
    • 0035812845 scopus 로고    scopus 로고
    • The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
    • Hemann, M. T., Strong, M. A., Hao, L.-Y. and Greider, C. W. (2001). The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107, 67-77.
    • (2001) Cell , vol.107 , pp. 67-77
    • Hemann, M.T.1    Strong, M.A.2    Hao, L.-Y.3    Greider, C.W.4
  • 33
    • 2342473232 scopus 로고    scopus 로고
    • Human telomerase catalyzes nucleolytic primer cleavage
    • Huard, S. and Autexier, C. (2004). Human telomerase catalyzes nucleolytic primer cleavage. Nucleic Acids Res. 32, 2171-2180.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 2171-2180
    • Huard, S.1    Autexier, C.2
  • 34
    • 0242286004 scopus 로고    scopus 로고
    • The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity
    • DOI 10.1093/nar/gkg437
    • Huard, S., Moriarty, T. J. and Autexier, C. (2003). The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity. Nucleic Acids Res. 31, 4059-4070. (Pubitemid 37442286)
    • (2003) Nucleic Acids Research , vol.31 , Issue.14 , pp. 4059-4070
    • Huard, S.1    Moriarty, T.J.2    Autexier, C.3
  • 35
    • 1842789989 scopus 로고    scopus 로고
    • Mechanisms of cellular senescence in human and mouse cells
    • Itahana, K., Campisi, J. and Dimri, G. (2004). Mechanisms of cellular senescence in human and mouse cells. Biogerontology 5, 1-10.
    • (2004) Biogerontology , vol.5 , pp. 1-10
    • Itahana, K.1    Campisi, J.2    Dimri, G.3
  • 36
    • 0030743347 scopus 로고    scopus 로고
    • Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
    • Kim, N. W. and Wu, F. (1997). Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). Nucleic Acids Res. 25, 2595-2597.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2595-2597
    • Kim, N.W.1    Wu, F.2
  • 37
    • 0030950046 scopus 로고    scopus 로고
    • Telomere structure and telomerase expression during mouse development and tumorigenesis
    • Kipling, D. (1997). Telomere structure and telomerase expression during mouse development and tumorigenesis. Eur. J. Cancer 33, 792-800.
    • (1997) Eur. J. Cancer , vol.33 , pp. 792-800
    • Kipling, D.1
  • 40
    • 27244458940 scopus 로고    scopus 로고
    • A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation
    • Marie-Egyptienne, D. T., Cerone, M. A., Londono-Vallejo, J. A. and Autexier, C. (2005). A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation. Nucleic Acids Res. 33, 5446-5457.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 5446-5457
    • Marie-Egyptienne, D.T.1    Cerone, M.A.2    Londono-Vallejo, J.A.3    Autexier, C.4
  • 41
    • 38349049184 scopus 로고    scopus 로고
    • Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation
    • Marie-Egyptienne, D. T., Brault, M. E., Zhu, S. and Autexier, C. (2008). Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation. Exp. Cell Res. 314, 668-675.
    • (2008) Exp. Cell Res. , vol.314 , pp. 668-675
    • Marie-Egyptienne, D.T.1    Brault, M.E.2    Zhu, S.3    Autexier, C.4
  • 42
    • 0035937133 scopus 로고    scopus 로고
    • Identification of functional domains and dominant negative mutations in vertebrate telomerase RNA using an in vivo reconstitution system
    • Martin-Rivera, L. and Blasco, M. (2001). Identification of functional domains and dominant negative mutations in vertebrate telomerase RNA using an in vivo reconstitution system. J. Biol. Chem. 276, 5856-5865.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5856-5865
    • Martin-Rivera, L.1    Blasco, M.2
  • 44
    • 33644774920 scopus 로고    scopus 로고
    • Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain
    • Middleman, E. J., Choi, J., Venteicher, A. S., Cheung, P. and Artandi, S. E. (2006). Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain. Mol. Cell. Biol. 26, 2146-2159.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2146-2159
    • Middleman, E.J.1    Choi, J.2    Venteicher, A.S.3    Cheung, P.4    Artandi, S.E.5
  • 45
    • 0033636897 scopus 로고    scopus 로고
    • Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase
    • Mitchell, J. and Collins, K. (2000). Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase. Mol. Cell 6, 361-371.
    • (2000) Mol. Cell , vol.6 , pp. 361-371
    • Mitchell, J.1    Collins, K.2
  • 46
    • 0036150238 scopus 로고    scopus 로고
    • Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit
    • Moriarty, T. J., Huard, S., Dupuis, S. and Autexier, C. (2002). Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit. Mol. Cell. Biol. 22, 1253-1265.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1253-1265
    • Moriarty, T.J.1    Huard, S.2    Dupuis, S.3    Autexier, C.4
  • 47
    • 1942453903 scopus 로고    scopus 로고
    • Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer
    • Moriarty, T. J., Marie-Egyptienne, D. T. and Autexier, C. (2004). Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer. Mol. Cell. Biol. 24, 3720-3733.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3720-3733
    • Moriarty, T.J.1    Marie-Egyptienne, D.T.2    Autexier, C.3
  • 48
    • 21844457135 scopus 로고    scopus 로고
    • An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization
    • Moriarty, T. J., Ward, R. J., Taboski, M. A. and Autexier, C. (2005). An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization. Mol. Biol. Cell 16, 3152-3161.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 3152-3161
    • Moriarty, T.J.1    Ward, R.J.2    Taboski, M.A.3    Autexier, C.4
  • 49
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin, G. B. (1989). The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59, 521-529.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 51
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm, W. and de Lange, T. (2008). How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42, 301-334.
    • (2008) Annu. Rev. Genet. , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 52
    • 0034998040 scopus 로고    scopus 로고
    • Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells
    • Perrem, K., Colgin, L. M., Neumann, A. A., Yeager, T. R. and Reddel, R. R. (2001). Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells. Mol. Cell. Biol. 21, 3862-3875.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3862-3875
    • Perrem, K.1    Colgin, L.M.2    Neumann, A.A.3    Yeager, T.R.4    Reddel, R.R.5
  • 53
    • 0027467847 scopus 로고
    • Identification of a nonprocessive telomerase activity from mouse cells
    • Prowse, K. R., Avilion, A. A. and Greider, C. W. (1993). Identification of a nonprocessive telomerase activity from mouse cells. Proc. Natl. Acad. Sci. USA 90, 1493-1497.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1493-1497
    • Prowse, K.R.1    Avilion, A.A.2    Greider, C.W.3
  • 54
    • 0035878750 scopus 로고    scopus 로고
    • Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells
    • Sachsinger, J., Gonzalez-Suarez, E., Samper, E., Heicappell, R., Muller, M. and Blasco, M. A. (2001). Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells. Cancer Res. 61, 5580-5586.
    • (2001) Cancer Res. , vol.61 , pp. 5580-5586
    • Sachsinger, J.1    Gonzalez-Suarez, E.2    Samper, E.3    Heicappell, R.4    Muller, M.5    Blasco, M.A.6
  • 59
    • 2042534735 scopus 로고    scopus 로고
    • Telomere length homeostasis is achieved via a switch between telomerase- Extendible and -nonextendible states
    • DOI 10.1016/S0092-8674(04)00334-4, PII S0092867404003344
    • Teixeira, M. T., Arneric, M., Sperisen, P. and Lingner, J. (2004). Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117, 323-335. (Pubitemid 38534539)
    • (2004) Cell , vol.117 , Issue.3 , pp. 323-335
    • Teixeira, M.T.1    Arneric, M.2    Sperisen, P.3    Lingner, J.4
  • 61
    • 55549090746 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells
    • Tomlinson, R. L., Abreu, E. B., Ziegler, T., Ly, H., Counter, C. M., Terns, R. M. and Terns, M. P. (2008). Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. Mol. Biol. Cell 19, 3793-3800.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3793-3800
    • Tomlinson, R.L.1    Abreu, E.B.2    Ziegler, T.3    Ly, H.4    Counter, C.M.5    Terns, R.M.6    Terns, M.P.7
  • 62
    • 0032567967 scopus 로고    scopus 로고
    • Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
    • Vaziri, H. and Benchimol, S. (1998). Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr. Biol. 8, 279-282.
    • (1998) Curr. Biol. , vol.8 , pp. 279-282
    • Vaziri, H.1    Benchimol, S.2
  • 63
    • 0346336773 scopus 로고    scopus 로고
    • Telomerase inhibition with an oligonucleotide telomerase template antagonist: In vitro and in vivo studies in multiple myeloma and lymphoma
    • Wang, E. S., Wu, K., Chin, A. C., Chen-Kiang, S., Pongracz, K., Gryaznov, S. and Moore, M. A. S. (2004). Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma. Blood 103, 258-266.
    • (2004) Blood , vol.103 , pp. 258-266
    • Wang, E.S.1    Wu, K.2    Chin, A.C.3    Chen-Kiang, S.4    Pongracz, K.5    Gryaznov, S.6    Moore, M.A.S.7
  • 64
    • 33846691378 scopus 로고    scopus 로고
    • The POT1-TPP1 telomere complex is a telomerase processivity factor
    • Wang, F., Podell, E. R., Zaug, A. J., Yang, Y., Baciu, P., Cech, T. R. and Lei, M. (2007). The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 445, 506-510.
    • (2007) Nature , vol.445 , pp. 506-510
    • Wang, F.1    Podell, E.R.2    Zaug, A.J.3    Yang, Y.4    Baciu, P.5    Cech, T.R.6    Lei, M.7
  • 65
    • 0031801205 scopus 로고    scopus 로고
    • Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells
    • Wen, J., Cong, Y. and Bacchetti, S. (1998). Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells. Hum. Mol. Genet. 7, 1137-1141.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1137-1141
    • Wen, J.1    Cong, Y.2    Bacchetti, S.3
  • 66
    • 34147194788 scopus 로고    scopus 로고
    • Characterization of physical and functional anchor site interactions in human telomerase
    • Wyatt, H. D., Lobb, D. A. and Beattie, T. L. (2007). Characterization of physical and functional anchor site interactions in human telomerase. Mol. Cell. Biol. 27, 3226-3240.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3226-3240
    • Wyatt, H.D.1    Lobb, D.A.2    Beattie, T.L.3
  • 67
    • 33846692105 scopus 로고    scopus 로고
    • TPP1 is a homologue of ciliate TEBP-[beta] and interacts with POT1 to recruit telomerase
    • Xin, H., Liu, D., Wan, M., Safari, A., Kim, H., Sun, W., O'Connor, M. S. and Songyang, Z. (2007). TPP1 is a homologue of ciliate TEBP-[beta] and interacts with POT1 to recruit telomerase. Nature 445, 559-562.
    • (2007) Nature , vol.445 , pp. 559-562
    • Xin, H.1    Liu, D.2    Wan, M.3    Safari, A.4    Kim, H.5    Sun, W.6    O'Connor, M.S.7    Songyang, Z.8
  • 68
    • 33645009269 scopus 로고    scopus 로고
    • The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity
    • Zhang, D.-H., Zhou, B., Huang, Y., Xu, L.-X. and Zhou, J.-Q. (2006). The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity. Nucleic Acids Res. 34, 1393-1404.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1393-1404
    • Zhang, D.-H.1    Zhou, B.2    Huang, Y.3    Xu, L.-X.4    Zhou, J.-Q.5
  • 69
    • 0035798379 scopus 로고    scopus 로고
    • The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
    • Zhou, X. Z. and Lu, K. P. (2001). The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. Cell 107, 347-359.
    • (2001) Cell , vol.107 , pp. 347-359
    • Zhou, X.Z.1    Lu, K.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.