-
1
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn,E.H. (2001) Switching and signaling at the telomere. Cell, 106, 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
2
-
-
0037148278
-
Telomere dysfunction: Multiple paths to the same end
-
Harrington,L. and Robinson,M.O. (2002) Telomere dysfunction: multiple paths to the same end. Oncogene, 21, 592-597.
-
(2002)
Oncogene
, vol.21
, pp. 592-597
-
-
Harrington, L.1
Robinson, M.O.2
-
3
-
-
0038701907
-
Biochemical aspects of telomerase function
-
Harrington,L. (2003) Biochemical aspects of telomerase function. Cancer Lett., 194, 139-154.
-
(2003)
Cancer Lett.
, vol.194
, pp. 139-154
-
-
Harrington, L.1
-
4
-
-
0025743438
-
Telomerase primer specificity and chromosome healing
-
Harrington,L.A. and Greider,C.W. (1991) Telomerase primer specificity and chromosome healing. Nature, 353, 451-454.
-
(1991)
Nature
, vol.353
, pp. 451-454
-
-
Harrington, L.A.1
Greider, C.W.2
-
5
-
-
0030131123
-
Chromosome healing: Spontaneous and programmed de novo telomere formation by telomerase
-
Melek,M. and Shippen,D.E. (1996) Chromosome healing: spontaneous and programmed de novo telomere formation by telomerase. BioEssays, 18, 301-308.
-
(1996)
BioEssays
, vol.18
, pp. 301-308
-
-
Melek, M.1
Shippen, D.E.2
-
6
-
-
0030977010
-
Developmentally regulated initiation of DNA synthesis by telomerase: Evidence for factor-assisted de novo telomere formation
-
Bednenko,J., Melek,M., Greene,E.C. and Shippen,D.E. (1997) Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation. EMBO J., 16, 2507-2518.
-
(1997)
EMBO J.
, vol.16
, pp. 2507-2518
-
-
Bednenko, J.1
Melek, M.2
Greene, E.C.3
Shippen, D.E.4
-
7
-
-
0031053530
-
De novo telomere addition by Tetrahymena telomerase in vitro
-
Wang,H. and Blackburn,E.H. (1997) De novo telomere addition by Tetrahymena telomerase in vitro. EMBO J., 16, 866-879.
-
(1997)
EMBO J.
, vol.16
, pp. 866-879
-
-
Wang, H.1
Blackburn, E.H.2
-
8
-
-
0029096515
-
The RNA component of human telomerase
-
Feng,J., Funk,W.D., Wang,S.-S., Weinrich,S.L., Avilion,A.A., Chiu,C.-P., Adams,R.R., Chang,E., Allsopp,R.C., Yu,J., Le,S., West,M.D., Harley,C.B. Andrews,W.H., Greider,C.W. and Villeponteau,B. (1995) The RNA component of human telomerase. Science, 269, 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.-S.3
Weinrich, S.L.4
Avilion, A.A.5
Chiu, C.-P.6
Adams, R.R.7
Chang, E.8
Allsopp, R.C.9
Yu, J.10
Le, S.11
West, M.D.12
Harley, C.B.13
Andrews, W.H.14
Greider, C.W.15
Villeponteau, B.16
-
9
-
-
0030659644
-
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
-
Weinrich,S.L., Pruzan,R., Ma,L., Ouellette,M., Tesmer,V.M., Holt,S.E., Bodnar,A.G., Lichtsteiner,S., Kim,N.W., Trager,J.B., Taylor,R.D., Carlos,R., Andrews,W.H., Wright,W.E., Shay,J.W., Harley,C.B. and Morin,G.B. (1997) Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nature Genet., 17, 498-502.
-
(1997)
Nature Genet.
, vol.17
, pp. 498-502
-
-
Weinrich, S.L.1
Pruzan, R.2
Ma, L.3
Ouellette, M.4
Tesmer, V.M.5
Holt, S.E.6
Bodnar, A.G.7
Lichtsteiner, S.8
Kim, N.W.9
Trager, J.B.10
Taylor, R.D.11
Carlos, R.12
Andrews, W.H.13
Wright, W.E.14
Shay, J.W.15
Harley, C.B.16
Morin, G.B.17
-
10
-
-
0032576733
-
Reconstitution of human telomerase activity in vitro
-
Beattie,T.L., Zhou,W., Robinson,M.O. and Harrington,L. (1998) Reconstitution of human telomerase activity in vitro. Curr. Biol., 8, 177-180.
-
(1998)
Curr. Biol.
, vol.8
, pp. 177-180
-
-
Beattie, T.L.1
Zhou, W.2
Robinson, M.O.3
Harrington, L.4
-
11
-
-
0034598919
-
Secondary structure of vertebrate telomerase RNA
-
Chen,J.-L., Blasco,M.A. and Greider,C.W. (2000) Secondary structure of vertebrate telomerase RNA. Cell, 100, 503-514.
-
(2000)
Cell
, vol.100
, pp. 503-514
-
-
Chen, J.-L.1
Blasco, M.A.2
Greider, C.W.3
-
12
-
-
0024325562
-
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
-
Morin,G.B. (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521-529
-
(1989)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.B.1
-
13
-
-
0032520642
-
Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer
-
Lue,N.F. and Peng,Y. (1998) Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer. Nucleic Acids Res., 26, 1487-1494.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1487-1494
-
-
Lue, N.F.1
Peng, Y.2
-
14
-
-
0033616833
-
Regulation of catalytic activity and processivity of human telomerase
-
Sun,D., Lopez-Guajardo,C.C., Quada,J., Hurley,L.H. and Von Hoff,D.D. (1999) Regulation of catalytic activity and processivity of human telomerase. Biochemistry, 38, 4037-4044.
-
(1999)
Biochemistry
, vol.38
, pp. 4037-4044
-
-
Sun, D.1
Lopez-Guajardo, C.C.2
Quada, J.3
Hurley, L.H.4
Von Hoff, D.D.5
-
15
-
-
0037115823
-
Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: Implications for primer positioning by the enzyme
-
Baran,N., Haviv,Y., Paul,B. and Manor,H. (2002) Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: implications for primer positioning by the enzyme. Nucleic Acids Res., 30, 5570-5578.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 5570-5578
-
-
Baran, N.1
Haviv, Y.2
Paul, B.3
Manor, H.4
-
16
-
-
0037457831
-
Interaction of human telomerase with its primer substrate
-
Wallweber,G., Gryaznov,S., Pongracz,K. and Pruzan,R. (2003) Interaction of human telomerase with its primer substrate. Biochemistry, 42, 589-600.
-
(2003)
Biochemistry
, vol.42
, pp. 589-600
-
-
Wallweber, G.1
Gryaznov, S.2
Pongracz, K.3
Pruzan, R.4
-
17
-
-
0242286004
-
The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity
-
Huard,S., Moriarty,T.J. and Autexier,C. (2003) The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity. Nucleic Acids Res., 31, 4059-4070.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4059-4070
-
-
Huard, S.1
Moriarty, T.J.2
Autexier, C.3
-
18
-
-
0029894237
-
Telomere length regulation
-
Greider,C.W. (1996) Telomere length regulation. Annu. Rev. Biochem., 65, 337-365.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
19
-
-
0025914141
-
Telomerase is processive
-
Greider,C.W. (1991) Telomerase is processive. Mol. Cell. Biol., 11, 4572-4580.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4572-4580
-
-
Greider, C.W.1
-
20
-
-
0027275438
-
Tetrahymena telomerase catalyzes nucleolytic: Cleavage and nonprocessive elongation
-
Collins,K. and Greider,C.W. (1993) Tetrahymena telomerase catalyzes nucleolytic: cleavage and nonprocessive elongation. Genes Dev., 7, 1364-1376.
-
(1993)
Genes Dev.
, vol.7
, pp. 1364-1376
-
-
Collins, K.1
Greider, C.W.2
-
21
-
-
0031026387
-
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers
-
Hammond,P.W., Lively,T.N. and Cech,T.R. (1997) The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers. Mol. Cell. Biol., 17, 296-308.
-
(1997)
Cell. Biol. Mol.
, vol.17
, pp. 296-308
-
-
Hammond, P.W.1
Lively, T.N.2
Cech, T.R.3
-
22
-
-
0036016447
-
Hübscher,U. The 3′-5′ exonucleases
-
Shevelev,I.V. and Hübscher,U. (2002) The 3′-5′ exonucleases. Nat. Rev. Mol. Cell Biol., 3, 1-12.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 1-12
-
-
Shevelev, I.V.1
-
23
-
-
0141785208
-
Running with RNA polymerase: Eukaryotic transcript elongation
-
Arndt,K.M. and Kane,C.M. (2003) Running with RNA polymerase: eukaryotic transcript elongation. Trends Genet., 19, 543-550.
-
(2003)
Trends Genet.
, vol.19
, pp. 543-550
-
-
Arndt, K.M.1
Kane, C.M.2
-
24
-
-
0029155795
-
Telomerase in yeast
-
Cohn,M. and Blackburn,E.H. (1995) Telomerase in yeast. Science, 269, 396-400.
-
(1995)
Science
, vol.269
, pp. 396-400
-
-
Cohn, M.1
Blackburn, E.H.2
-
25
-
-
0029895352
-
Processing of nontelomeric 3′ ends by telomerase: Default template alignment and endonucleolytic: Cleavage
-
Melek,M., Greene,E.C. and Shippen,D.E. (1996) Processing of nontelomeric 3′ ends by telomerase: default template alignment and endonucleolytic: cleavage. Mol. Cell. Biol., 16, 3437-3445.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3437-3445
-
-
Melek, M.1
Greene, E.C.2
Shippen, D.E.3
-
26
-
-
0030678086
-
Identification and characterization of a telomerase activity from Schizosaccharomyces pombe
-
Lue,N.F. and Peng,Y. (1997) Identification and characterization of a telomerase activity from Schizosaccharomyces pombe. Nucleic Acids Res., 25, 4331-4337.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4331-4337
-
-
Lue, N.F.1
Peng, Y.2
-
27
-
-
0033816358
-
Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex
-
Niu,H., Xia,J. and Lue,N.F. (2000) Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex. Mol. Cell. Biol., 20, 6806-6815.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6806-6815
-
-
Niu, H.1
Xia, J.2
Lue, N.F.3
-
28
-
-
0031910117
-
Flexible positioning of the telomerase-associated nuclease leads to preferential elimination of nontelomeric DNA
-
Greene,E.C., Bednenko,J. and Shippen,D.E. (1998) Flexible positioning of the telomerase-associated nuclease leads to preferential elimination of nontelomeric DNA. Mol. Cell. Biol., 18, 1544-1552.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1544-1552
-
-
Greene, E.C.1
Bednenko, J.2
Shippen, D.E.3
-
29
-
-
0034659801
-
Three telomerases with completely non-telomeric template replacements are catalytically active
-
Ware,T.L., Wang,H. and Blackburn,E.H. (2000) Three telomerases with completely non-telomeric template replacements are catalytically active. EMBO J., 19, 3119-3131.
-
(2000)
EMBO J.
, vol.19
, pp. 3119-3131
-
-
Ware, T.L.1
Wang, H.2
Blackburn, E.H.3
-
30
-
-
0031006535
-
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
-
Bhattacharyya,A. and Blackburn,E.H. (1997) A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains. Proc. Natl Acad. Sci. USA, 94, 2823-2827.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2823-2827
-
-
Bhattacharyya, A.1
Blackburn, E.H.2
-
31
-
-
0032555261
-
The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex
-
Collins,K. and Gandhi,L. (1998) The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex. Proc. Natl Acad. Sci. USA, 95, 8485-8490.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8485-8490
-
-
Collins, K.1
Gandhi, L.2
-
32
-
-
0029958047
-
Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA
-
Autexier,C., Pruzan,R., Funk,W.D. and Greider,C.W. (1996) Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. EMBO J., 15, 5928-5935.
-
(1996)
EMBO J.
, vol.15
, pp. 5928-5935
-
-
Autexier, C.1
Pruzan, R.2
Funk, W.D.3
Greider, C.W.4
-
33
-
-
0033621463
-
Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae
-
Bachand,F. and Autexier,C. (1999) Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae. J. Biol. Chem., 274, 38027-38031.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 38027-38031
-
-
Bachand, F.1
Autexier, C.2
-
34
-
-
0036150238
-
Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit
-
Moriarty,T.J., Huard,S., Dupuis,S. and Autexier,C. (2002) Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit. Mol. Cell. Biol., 22, 1253-1265.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1253-1265
-
-
Moriarty, T.J.1
Huard, S.2
Dupuis, S.3
Autexier, C.4
-
35
-
-
0037439107
-
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
-
Chen,J.-L. and Greider,C.W. (2003) Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. EMBO J., 22, 304-314.
-
(2003)
EMBO J.
, vol.22
, pp. 304-314
-
-
Chen, J.-L.1
Greider, C.W.2
-
36
-
-
0030850982
-
dGTP-dependent processivity and possible template switching of Euplotes telomerase
-
Hammond,P.W. and Cech,T.R. (1997) dGTP-dependent processivity and possible template switching of Euplotes telomerase. Nucleic Acids Res., 25, 3698-3704.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3698-3704
-
-
Hammond, P.W.1
Cech, T.R.2
-
37
-
-
0035895954
-
Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase
-
Hardy,C.D., Schultz,C.S. and Collins,K. (2001) Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase. J. Biol. Chem., 276, 4863-4871.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4863-4871
-
-
Hardy, C.D.1
Schultz, C.S.2
Collins, K.3
-
38
-
-
0034604578
-
A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity
-
Bryan,T.M., Goodrich,K.J. and Cech,T.R. (2000) A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity. J. Biol. Chem., 275, 24199-24207.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24199-24207
-
-
Bryan, T.M.1
Goodrich, K.J.2
Cech, T.R.3
-
39
-
-
0031029377
-
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro
-
Prescott,J. and Blackburn,E.H. (1997) Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro. Genes Dev., 11, 528-540.
-
(1997)
Genes Dev.
, vol.11
, pp. 528-540
-
-
Prescott, J.1
Blackburn, E.H.2
-
40
-
-
0028269621
-
Functional reconstitution of wild-type and mutant Tetrahymena telomerase
-
Autexier,C. and Greider,C.W. (1994) Functional reconstitution of wild-type and mutant Tetrahymena telomerase. Genes Dev., 8, 563-575.
-
(1994)
Genes Dev.
, vol.8
, pp. 563-575
-
-
Autexier, C.1
Greider, C.W.2
-
41
-
-
0019568388
-
All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus
-
Klobutcher,L.A., Swanton,M.T., Donini,P. and Prescott,D.M. (1981) All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus. Proc. Natl Acad. Sci. USA, 78, 3015-3019.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3015-3019
-
-
Klobutcher, L.A.1
Swanton, M.T.2
Donini, P.3
Prescott, D.M.4
-
43
-
-
0025808098
-
Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase
-
Morin,G.B. (1991) Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase. Nature, 353, 454-456.
-
(1991)
Nature
, vol.353
, pp. 454-456
-
-
Morin, G.B.1
-
44
-
-
0030928859
-
Nuclease activity of T7 RNA polymerase and the heterogeneity of transcription elongation complexes 44
-
Sastry,S.S. and Ross,B.M. (1997) Nuclease activity of T7 RNA polymerase and the heterogeneity of transcription elongation complexes. J. Biol. Chem., 272, 8644-8652.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8644-8652
-
-
Sastry, S.S.1
Ross, B.M.2
|