Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

Arthritis and Rheumatism

Volumn 60, Issue 7, 2009, Pages 2102-2112

  Barnes, Michael G ^a,g   Grom, Alexei A ^a,g   Thompson, Susan D ^a,g   Griffin, Thomas A ^a,g   Pavlidis, Paul ^b   Itert, Lukasz ^a,g   Fall, Ndate ^a,g   Sowders, Dawn Paxson ^a,g   Hinze, Claas H ^a,g   Aronow, Bruce J ^a,g   Luyrink, Lorie K ^a,g   Srivastava, Shweta ^a,g   Ilowite, Norman T ^c   Gottlieb, Beth S ^d   Olson, Judyann C ^e   Sherry, David D ^f   Glass, David N ^a,g   Colbert, Robert A ^a,g  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d SCHNEIDER CHILDREN'S HOSPITAL   (United States)

^e CHILDREN S HOSPITAL OF WISCONSIN   (United States)

^f CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^g NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CYCLOSPORIN A; INTERLEUKIN 10; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; POLYADENYLATED RNA; STAT PROTEIN;

ADOLESCENT; ANALYSIS OF VARIANCE; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE CLASSIFICATION; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ANTIRHEUMATIC AGENTS; ARTHRITIS; ARTHRITIS, JUVENILE RHEUMATOID; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFANT; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RECEPTORS, INTERLEUKIN-1; TOLL-LIKE RECEPTORS;

EID: 67650066800     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24601     Document Type: Article

References (37)

1. Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol 2004;31:390-2.
2. Prahalad S, Glass DN. A comprehensive review of the genetics of juvenile idiopathic arthritis. Pediatr Rheumatol Online J 2008;6:11.
3. Donn RP, Ollier WE. Juvenile chronic arthritis - a time for change? Eur J Immunogenet 1996;23:245-60.
4. Thompson SD, Moroldo MB, Guyer L, Ryan M, Tombragel EM, Shear ES, et al. A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage. Arthritis Rheum 2004;50:2920-30.
5. Bennett L, Palucka AK, Arce E, Cantrell V, Borvak J, Banchereau J, et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med 2003;197:711-23.
6. Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, et al. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum 2007;56:3793-804.
7. Barnes MG, Aronow BJ, Luyrink LK, Moroldo MB, Pavlidis P, Passo MH, et al. Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis. Rheumatology (Oxford) 2004;43:973-9.
8. Ogilvie EM, Khan A, Hubank M, Kellam P, Woo P. Specific gene expression profiles in systemic juvenile idiopathic arthritis. Arthritis Rheum 2007;56:1954-65.
9. Jarvis JN, Dozmorov I, Jiang K, Frank MB, Szodoray P, Alex P, et al. Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis. Arthritis Res Ther 2004;6:R15-32.
10. Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, Mejias A, et al. Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J Exp Med 2007;204:2131-44.
11. Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, et al. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 1998;25:1991-4.
12. Marron JS, Todd MJ, Ahn J. Distance weighted discrimination. J Am Stat Assoc 2007;102:1267-71.
13. Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, et al. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med 2006;3:e467.
14. Benito M, Parker J, Du Q, Wu J, Xiang D, Perou CM, et al. Adjustment of systematic microarray data biases. Bioinformatics 2004;20:105-14.
15. Hu Z, Fan C, Oh DS, Marron JS, He X, Qaqish BF, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006;7:96.
16. Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007;8:R76.
17. Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002;30:207-10.
18. Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, et al. Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics 2004;19:247-54.
19. Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, et al. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun 2004;5:347-53.
20. Burczynski ME, Peterson RL, Twine NC, Zuberek KA, Brodeur BJ, Casciotti L, et al. Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. J Mol Diagn 2006;8:51-61.
21. Greene JG, Greenamyre JT, Dingledine R. Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism. Neuroscience 2008;152:198-207.
22. Kanehisa M, Goto S, Kawashima S, Nakaya A. The KEGG databases at GenomeNet. Nucleic Acids Res 2002;30:42-6.
23. Alper CA, Johnson AM, Birtch AG, Moore FD. Human C′3: evidence for the liver as the primary site of synthesis. Science 1969;163:286-8.
24. Cao W, Bobryshev YV, Lord RS, Oakley RE, Lee SH, Lu J. Dendritic cells in the arterial wall express C1q: potential significance in atherogenesis. Cardiovasc Res 2003;60:175-86.
25. Castellano G, Woltman AM, Nauta AJ, Roos A, Trouw LA, Seelen MA, et al. Maturation of dendritic cells abrogates C1q production in vivo and in vitro. Blood 2004;103:3813-20.
26. Lu J, Wu X, Teh BK. The regulatory roles of C1q. Immunobiology 2007;212:245-52.
27. Muller W, Hanauske-Abel H, Loos M. Biosynthesis of the first component of complement by human and guinea pig peritoneal macrophages: evidence for an independent production of the C1 subunits. J Immunol 1978;121:1578-84.
28. Vincent F, de la Salle H, Bohbot A, Bergerat JP, Hauptmann G, Oberling F. Synthesis and regulation of complement components by human monocytes/ macrophages and by acute monocytic leukemia. DNA Cell Biol 1993;12:415-23.
29. Vincent F, Eischen A, de la Salle H, Bergerat JP, Faradji A, Hauptman G, et al. Synthesis of complement components C2 and C4 by human monocyte-derived macrophages during in vitro differentiation in serum-free culture conditions. Pathobiology 1991;59:136-9.
30. Shanley TP, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, et al. Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol Med 2007;13:495-508.
31. Gattorno M, Piccini A, Lasiglie D, Tassi S, Brisca G, Carta S, et al. The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2008;58:1505-15.
32. Golding DN. Hematology and biochemistry of ankylosing spondylitis [letter]. Br Med J 1973;2:663.
33. Braun J, Bollow M, Neure L, Seipelt E, Seyrekbasan F, Herbst H, et al. Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum 1995;38:499-505.
34. Little JA, Dempsey NJ, Tuchman M, Ginder GD. Metabolic persistence of fetal hemoglobin. Blood 1995;85:1712-8.
35. Umemura T, Al-Khatti A, Papayannopoulou T, Stamatoyannopoulos G. Fetal hemoglobin synthesis in vivo: direct evidence for control at the level of erythroid progenitors. Proc Natl Acad Sci U S A 1988;85:9278-82.
36. Bloom BJ, Tucker LB, Miller LC, Schaller JG. Fibrin D-dimer as a marker of disease activity in systemic onset juvenile rheumatoid arthritis. J Rheumatol 1998;25:1620-5.
37. Gallistl S, Mangge H, Neuwirth G, Muntean W. Activation of the haemostatic system in children with juvenile rheumatoid arthritis correlates with disease activity. Thromb Res 1998;92:267-72.