메뉴 건너뛰기




Volumn 5, Issue , 2010, Pages

Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)

Author keywords

[No Author keywords available]

Indexed keywords

11,12 DIDEHYDRO 14 DEOXYANDROGRAPHOLIDE; 12 HYDROXY 14 DEHYDROANDROGRAPHOLIDE; 14 ACETYL 3,19 ISOPROPYLIDENE ANDROGRAPHOLIDE; 14 ACETYLANDROGRAPHOLIDE; 14 ALPHAL LIPOYLANDROGRAPHOLIDE; 14 DEOXY 14,15 DEHYDROANDROGRAPHOLIDE; 14 DEOXY 14,15 DIDEHYDROANDROGRAPHOLIDE; 14 DEOXYANDROGRAPHOLIDE; 14 GLYCINYLANDROGRAPHOLIDE; 19 O ACETYLANHYDROANDROGRAPHOLIDE; 3,19 ISOPROPYLIDENEANDROGRAPHOLIDE; 3,19 ISOPROPYLLIDENEANDROGRAPHOLIDE; 3,19 O DIACETYLANHYDROANDROGRAPHOLIDE; 3,4 DICAFFEOYLQUINIC ACID; 5 HYDROXY 7,8 DIMETHOXYFLAVONE; 5 HYDROXY 7,8,2',5' TETRAMETHOXYFLAVONE; 7 O METHYLWOGONIN; ANDROGRAPANIN; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; APIGENIN; DRF 3188; ISOANDROGRAPHOLIDE; NEOANDROGRAPHOLIDE; ONYSILIN; SRJ 09; SRJ 23; UNCLASSIFIED DRUG;

EID: 77952055014     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-5-17     Document Type: Review
Times cited : (294)

References (124)
  • 1
    • 50249134405 scopus 로고    scopus 로고
    • Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads
    • Negi AS, Kumar JK, Luqman S, Sbanker K, Gupta MM, Kbanuja SPS. Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads. Med Res Rev 2008, 28(5):821.
    • (2008) Med Res Rev , vol.28 , Issue.5 , pp. 821
    • Negi, A.S.1    Kumar, J.K.2    Luqman, S.3    Sbanker, K.4    Gupta, M.M.5    Kbanuja, S.P.S.6
  • 2
    • 34247607597 scopus 로고    scopus 로고
    • Colds and influenza: A review of diagnosis and conventional, botanical and nutritional considerations
    • Roxas M, Jurenka J. Colds and influenza: A review of diagnosis and conventional, botanical and nutritional considerations. Altern Med Rev 2007, 12:25-48.
    • (2007) Altern Med Rev , vol.12 , pp. 25-48
    • Roxas, M.1    Jurenka, J.2
  • 4
    • 0346192197 scopus 로고    scopus 로고
    • Differential effects of foods traditionally regarded as 'heating' and 'cooling' on prostaglandin E2 production by a macrophage cell line
    • Huang CJ, Wu MC. Differential effects of foods traditionally regarded as 'heating' and 'cooling' on prostaglandin E2 production by a macrophage cell line. J Biomed Sci 2002, 9:596-606.
    • (2002) J Biomed Sci , vol.9 , pp. 596-606
    • Huang, C.J.1    Wu, M.C.2
  • 5
    • 59849084324 scopus 로고    scopus 로고
    • The production of nitric oxide and prostaglandin E2 in peritoneal macrophages is inhibited by Andrographis paniculata, Angelica sinensis and Morus alba ethyl acetate fractions
    • 10.1016/j.jep.2008.11.029, 19111919
    • Chao WW, Kuo YH, Li WC, Lin BF. The production of nitric oxide and prostaglandin E2 in peritoneal macrophages is inhibited by Andrographis paniculata, Angelica sinensis and Morus alba ethyl acetate fractions. J Ethnopharmacol 2009, 122:68-75. 10.1016/j.jep.2008.11.029, 19111919.
    • (2009) J Ethnopharmacol , vol.122 , pp. 68-75
    • Chao, W.W.1    Kuo, Y.H.2    Li, W.C.3    Lin, B.F.4
  • 6
    • 0035019254 scopus 로고    scopus 로고
    • Studies on Psychopharmacological Activity of Andrographis paniculata Extract
    • 10.1002/ptr.704, 11351363
    • Mandal SC, Dhara AK, Maiti BC. Studies on Psychopharmacological Activity of Andrographis paniculata Extract. Phytother Res 2001, 15:253-256. 10.1002/ptr.704, 11351363.
    • (2001) Phytother Res , vol.15 , pp. 253-256
    • Mandal, S.C.1    Dhara, A.K.2    Maiti, B.C.3
  • 7
    • 4544257740 scopus 로고    scopus 로고
    • Flavonoids and andrographolides from Andrographis paniculata
    • 10.1016/j.phytochem.2004.05.008, 15381002
    • Rao YK, Vimalamma G, Rao CV, Tzeng Y. Flavonoids and andrographolides from Andrographis paniculata. Phytochemistry 2004, 65:2317-2321. 10.1016/j.phytochem.2004.05.008, 15381002.
    • (2004) Phytochemistry , vol.65 , pp. 2317-2321
    • Rao, Y.K.1    Vimalamma, G.2    Rao, C.V.3    Tzeng, Y.4
  • 8
    • 77954176415 scopus 로고    scopus 로고
    • A new diterpene from the leaves of Andrographis paniculata Nees
    • Xu C, Chou GX, Wang ZT. A new diterpene from the leaves of Andrographis paniculata Nees. Fitoterapia 2010,
    • (2010) Fitoterapia
    • Xu, C.1    Chou, G.X.2    Wang, Z.T.3
  • 9
    • 0035964762 scopus 로고    scopus 로고
    • Determination of bioactive diterpenoids from Andrographis paniculata by micellar electrokinetic chromatography
    • 10.1016/S0021-9673(01)01160-8, 11681575
    • Cheung HY, Cheung CS, Kong CK. Determination of bioactive diterpenoids from Andrographis paniculata by micellar electrokinetic chromatography. J Chromatogr A 2001, 930(1-2):171-176. 10.1016/S0021-9673(01)01160-8, 11681575.
    • (2001) J Chromatogr A , vol.930 , Issue.1-2 , pp. 171-176
    • Cheung, H.Y.1    Cheung, C.S.2    Kong, C.K.3
  • 11
    • 9944239247 scopus 로고    scopus 로고
    • Determination and variation of three active diterpenoids in Andrographis paniculata (Burm.f.) Nees
    • 10.1002/pca.789, 15595451
    • Pholphana N, Rangkadilok N, Thongnest S, Ruchirawat S, Ruchirawat M, Satayavivad J. Determination and variation of three active diterpenoids in Andrographis paniculata (Burm.f.) Nees. Phytochem Anal 2004, 15(6):365-371. 10.1002/pca.789, 15595451.
    • (2004) Phytochem Anal , vol.15 , Issue.6 , pp. 365-371
    • Pholphana, N.1    Rangkadilok, N.2    Thongnest, S.3    Ruchirawat, S.4    Ruchirawat, M.5    Satayavivad, J.6
  • 12
  • 13
    • 35848943019 scopus 로고    scopus 로고
    • Synthesis of andrographolide derivatives and their TNF-alpha and IL-6 expression inhibitory activities
    • 10.1016/j.bmcl.2007.10.009, 17962017
    • Li J, Huang W, Zhang H, Wang X, Zhou H. Synthesis of andrographolide derivatives and their TNF-alpha and IL-6 expression inhibitory activities. Bioorg Med Chem Lett 2007, 17(24):6891-6894. 10.1016/j.bmcl.2007.10.009, 17962017.
    • (2007) Bioorg Med Chem Lett , vol.17 , Issue.24 , pp. 6891-6894
    • Li, J.1    Huang, W.2    Zhang, H.3    Wang, X.4    Zhou, H.5
  • 14
    • 0030609172 scopus 로고    scopus 로고
    • Testicular toxicity assessment of Andrographis paniculata dried extract in rats
    • 10.1016/S0378-8741(97)00099-8, 9421258
    • Burgos RA, Caballero EE, Sánchez NS, Schroeder RA, Wikman GK, Hancke JL. Testicular toxicity assessment of Andrographis paniculata dried extract in rats. J Ethnopharmacol 1997, 58(3):219-224. 10.1016/S0378-8741(97)00099-8, 9421258.
    • (1997) J Ethnopharmacol , vol.58 , Issue.3 , pp. 219-224
    • Burgos, R.A.1    Caballero, E.E.2    Sánchez, N.S.3    Schroeder, R.A.4    Wikman, G.K.5    Hancke, J.L.6
  • 15
    • 0037332067 scopus 로고    scopus 로고
    • New 2'-oxygenated flavonoids from Andrographis affinis
    • 10.1021/np020331k, 12608871
    • Reddy MVB, Kishore PH, Rao CV, Gunasekar D, Caux C, Bodo B. New 2'-oxygenated flavonoids from Andrographis affinis. J Nat Prod 2003, 66:295-297. 10.1021/np020331k, 12608871.
    • (2003) J Nat Prod , vol.66 , pp. 295-297
    • Reddy, M.V.B.1    Kishore, P.H.2    Rao, C.V.3    Gunasekar, D.4    Caux, C.5    Bodo, B.6
  • 17
    • 77249174822 scopus 로고    scopus 로고
    • Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-κB Trans-Activation inhibition
    • 10.1021/jf903629j, 20085279
    • Chao WW, Kuo YH, Lin BF. Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-κB Trans-Activation inhibition. J Agric Food Chem 2010, 58:2505-2512. 10.1021/jf903629j, 20085279.
    • (2010) J Agric Food Chem , vol.58 , pp. 2505-2512
    • Chao, W.W.1    Kuo, Y.H.2    Lin, B.F.3
  • 18
    • 77950499149 scopus 로고    scopus 로고
    • Flavones from the stem of Andrographis paniculata Nees
    • Radhika P, Prasad YR, Lakshmi KR. Flavones from the stem of Andrographis paniculata Nees. Nat Prod Commun 2010, 5(1):59-60.
    • (2010) Nat Prod Commun , vol.5 , Issue.1 , pp. 59-60
    • Radhika, P.1    Prasad, Y.R.2    Lakshmi, K.R.3
  • 20
    • 84986850987 scopus 로고
    • Carbon-13 NMR spectra of some labdane diterpenoids
    • Patra A, Mitra AK. Carbon-13 NMR spectra of some labdane diterpenoids. Org Magn Reson 1981, 17(4):301-302.
    • (1981) Org Magn Reson , vol.17 , Issue.4 , pp. 301-302
    • Patra, A.1    Mitra, A.K.2
  • 21
    • 85011210216 scopus 로고
    • On the diterpenoids of Andrographis paniculata: X-ray crystallographic analysis of andrographolide and structure determination of new minor diterpenoids
    • Fujita T, Fujita R, Takeda Y, Takaishi Y, Yamada T, Kido M, Miura I. On the diterpenoids of Andrographis paniculata: X-ray crystallographic analysis of andrographolide and structure determination of new minor diterpenoids. Chem Pharm Bull (Tokyo) 1984, 32(6):2117-2125.
    • (1984) Chem Pharm Bull (Tokyo) , vol.32 , Issue.6 , pp. 2117-2125
    • Fujita, T.1    Fujita, R.2    Takeda, Y.3    Takaishi, Y.4    Yamada, T.5    Kido, M.6    Miura, I.7
  • 22
    • 26244441533 scopus 로고    scopus 로고
    • Oxidant stress, inflammation and atherogenesis
    • 10.1191/0961203305lu2216oa, 16218483
    • Davì G, Falco A. Oxidant stress, inflammation and atherogenesis. Lupus 2005, 14:760-764. 10.1191/0961203305lu2216oa, 16218483.
    • (2005) Lupus , vol.14 , pp. 760-764
    • Davì, G.1    Falco, A.2
  • 23
    • 41549107522 scopus 로고    scopus 로고
    • Cytokine signaling modules in inflammatory responses
    • 10.1016/j.immuni.2008.03.002, 2782488, 18400190
    • O'Shea JJ, Murray PJ. Cytokine signaling modules in inflammatory responses. Immunity 2008, 28(4):477-87. 10.1016/j.immuni.2008.03.002, 2782488, 18400190.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 477-487
    • O'Shea, J.J.1    Murray, P.J.2
  • 24
    • 38149027125 scopus 로고    scopus 로고
    • Dietary strategies for improving post-prandial glucose, lipids, inflammation and cardiovascular health
    • 10.1016/j.jacc.2007.10.016, 18206731
    • O'keefe JH, Gheewala NM, O'keefe JO. Dietary strategies for improving post-prandial glucose, lipids, inflammation and cardiovascular health. J Am Coll Cardiol 2008, 51:249-255. 10.1016/j.jacc.2007.10.016, 18206731.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 249-255
    • O'keefe, J.H.1    Gheewala, N.M.2    O'keefe, J.O.3
  • 25
    • 68949104260 scopus 로고    scopus 로고
    • Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide induced inflammation in vitro and in vivo
    • 10.1186/1423-0127-16-64, 2720939, 19594948
    • Hong YH, Chao WW, Chen ML, Lin BF. Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide induced inflammation in vitro and in vivo. J Biomed Sci 2009, 16:64-75. 10.1186/1423-0127-16-64, 2720939, 19594948.
    • (2009) J Biomed Sci , vol.16 , pp. 64-75
    • Hong, Y.H.1    Chao, W.W.2    Chen, M.L.3    Lin, B.F.4
  • 26
    • 33646685475 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees
    • 10.1080/08923970600626007, 16684672
    • Sheeja K, Shihab PK, Kuttan G. Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees. Immunopharmacol Immunotoxicol 2006, 28(1):129-140. 10.1080/08923970600626007, 16684672.
    • (2006) Immunopharmacol Immunotoxicol , vol.28 , Issue.1 , pp. 129-140
    • Sheeja, K.1    Shihab, P.K.2    Kuttan, G.3
  • 27
    • 0031670451 scopus 로고    scopus 로고
    • Andrographolide suppresses the expression of inducible nitric oxide synthase in macrophage and restores the vasoconstriction in rat aorta treated with lipopolysaccharide
    • 10.1038/sj.bjp.0702073, 1565624, 9786505
    • Chiou WF, Lin JJ, Chen CF. Andrographolide suppresses the expression of inducible nitric oxide synthase in macrophage and restores the vasoconstriction in rat aorta treated with lipopolysaccharide. Br J Pharmacol 1998, 125(2):327-334. 10.1038/sj.bjp.0702073, 1565624, 9786505.
    • (1998) Br J Pharmacol , vol.125 , Issue.2 , pp. 327-334
    • Chiou, W.F.1    Lin, J.J.2    Chen, C.F.3
  • 28
    • 0034001308 scopus 로고    scopus 로고
    • Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in Raw264.7 cells by andrographolide
    • 10.1038/sj.bjp.0703191, 1571992, 10780958
    • Chiou WF, Chen CF, Lin JJ. Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in Raw264.7 cells by andrographolide. Br J Pharmacol 2000, 129:1553-1560. 10.1038/sj.bjp.0703191, 1571992, 10780958.
    • (2000) Br J Pharmacol , vol.129 , pp. 1553-1560
    • Chiou, W.F.1    Chen, C.F.2    Lin, J.J.3
  • 29
    • 0036181416 scopus 로고    scopus 로고
    • Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect
    • 10.1038/sj.bjp.0704493, 1573154, 11815375
    • Shen YC, Chen CF, Chiou WF. Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect. Br J Pharmacol 2002, 135(2):399-406. 10.1038/sj.bjp.0704493, 1573154, 11815375.
    • (2002) Br J Pharmacol , vol.135 , Issue.2 , pp. 399-406
    • Shen, Y.C.1    Chen, C.F.2    Chiou, W.F.3
  • 30
    • 4444376879 scopus 로고    scopus 로고
    • Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration
    • 10.1016/j.ejphar.2004.07.077, 15363974
    • Tsai HR, Yang LM, Tsai WJ, Chiou WF. Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration. Eur J Pharmacol 2004, 498(1-3):45-52. 10.1016/j.ejphar.2004.07.077, 15363974.
    • (2004) Eur J Pharmacol , vol.498 , Issue.1-3 , pp. 45-52
    • Tsai, H.R.1    Yang, L.M.2    Tsai, W.J.3    Chiou, W.F.4
  • 31
    • 4644241127 scopus 로고    scopus 로고
    • Andrographolide attenuates inflammation by inhibition of NF-κB activation through covalent modification of reduced cysteine 62 of p50
    • Xia YF, Ye BQ, Li YD, Wang JG, He XJ, Lin X. Andrographolide attenuates inflammation by inhibition of NF-κB activation through covalent modification of reduced cysteine 62 of p50. J Immunol 2004, 173:4207-4217.
    • (2004) J Immunol , vol.173 , pp. 4207-4217
    • Xia, Y.F.1    Ye, B.Q.2    Li, Y.D.3    Wang, J.G.4    He, X.J.5    Lin, X.6
  • 32
    • 15944409586 scopus 로고    scopus 로고
    • Andrographolide interferes with binding of nuclear factor-κB to DNA in HL-60-derived neutrophilic cells
    • 10.1038/sj.bjp.0706105, 1576048, 15678086
    • Hidalgo MA, Romero A, Figueroa J, Cortes P, Concha II, Hancke JL, Burgos RA. Andrographolide interferes with binding of nuclear factor-κB to DNA in HL-60-derived neutrophilic cells. Br J Pharmacol 2005, 144:680-686. 10.1038/sj.bjp.0706105, 1576048, 15678086.
    • (2005) Br J Pharmacol , vol.144 , pp. 680-686
    • Hidalgo, M.A.1    Romero, A.2    Figueroa, J.3    Cortes, P.4    Concha, I.I.5    Hancke, J.L.6    Burgos, R.A.7
  • 33
    • 32044450554 scopus 로고    scopus 로고
    • Andrographolide inhibits the production of TNF-α and IL-12 in LPS stimulated macrophages: role of mitogen activated protein kinases
    • 10.1248/bpb.29.220, 16462022
    • Qin LH, Kong L, Shi GJ, Wang ZT, Ge BX. Andrographolide inhibits the production of TNF-α and IL-12 in LPS stimulated macrophages: role of mitogen activated protein kinases. Biol Pharm Bull 2006, 29:220-224. 10.1248/bpb.29.220, 16462022.
    • (2006) Biol Pharm Bull , vol.29 , pp. 220-224
    • Qin, L.H.1    Kong, L.2    Shi, G.J.3    Wang, Z.T.4    Ge, B.X.5
  • 34
    • 0036728556 scopus 로고    scopus 로고
    • Suppression of NO production in activated macrophages in vitro and ex vivo by neoandrographolide isolated from Andrographis paniculata
    • 10.1248/bpb.25.1169, 12230111
    • Batkhuu J, Hattori K, Takano F, Fushiya S, Oshiman KI, Fujimiya Y. Suppression of NO production in activated macrophages in vitro and ex vivo by neoandrographolide isolated from Andrographis paniculata. Biol Pharm Bull 2002, 25:1169-1174. 10.1248/bpb.25.1169, 12230111.
    • (2002) Biol Pharm Bull , vol.25 , pp. 1169-1174
    • Batkhuu, J.1    Hattori, K.2    Takano, F.3    Fushiya, S.4    Oshiman, K.I.5    Fujimiya, Y.6
  • 35
    • 34247281583 scopus 로고    scopus 로고
    • Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E2 production in LPS-stimulated murine macrophage
    • 10.1007/s11010-006-9349-6, 17109078
    • Liu J, Wang ZT, Ji LL, Ge BX. Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E2 production in LPS-stimulated murine macrophage. Mol Cell Biochem 2007, 298:49-57. 10.1007/s11010-006-9349-6, 17109078.
    • (2007) Mol Cell Biochem , vol.298 , pp. 49-57
    • Liu, J.1    Wang, Z.T.2    Ji, L.L.3    Ge, B.X.4
  • 36
    • 34147220272 scopus 로고    scopus 로고
    • In vivo and in vitro anti-inflammatory activities of Neoandrographolide
    • 10.1142/S0192415X07004849, 17436371
    • Liu J, Wang ZT, Ji LL. In vivo and in vitro anti-inflammatory activities of Neoandrographolide. Am J Chin Med 2007, 35:317-328. 10.1142/S0192415X07004849, 17436371.
    • (2007) Am J Chin Med , vol.35 , pp. 317-328
    • Liu, J.1    Wang, Z.T.2    Ji, L.L.3
  • 37
    • 43649104402 scopus 로고    scopus 로고
    • Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide induced macrophage cells through down regulating the p38 MAPKs signaling pathways
    • 10.1016/j.intimp.2007.12.014, 18486905
    • Liu J, Wang ZT, Ge BX. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide induced macrophage cells through down regulating the p38 MAPKs signaling pathways. Int Immunopharmacol 2008, 8:951-958. 10.1016/j.intimp.2007.12.014, 18486905.
    • (2008) Int Immunopharmacol , vol.8 , pp. 951-958
    • Liu, J.1    Wang, Z.T.2    Ge, B.X.3
  • 38
    • 39149114470 scopus 로고    scopus 로고
    • Construction of promoters based immunity screening system and its application on the study of traditional Chinese medicine herbs
    • Chao WW, Kuo YH, Lin BF. Construction of promoters based immunity screening system and its application on the study of traditional Chinese medicine herbs. Taiwanese J Agric Chem Food Sci 2007, 45:193-205.
    • (2007) Taiwanese J Agric Chem Food Sci , vol.45 , pp. 193-205
    • Chao, W.W.1    Kuo, Y.H.2    Lin, B.F.3
  • 39
    • 79953273783 scopus 로고    scopus 로고
    • Inhibitory effects of ethyl acetate extract of Andrographis paniculata on NF-κB trans-activation activity and LPS-induced acute inflammation in mice
    • doi:10.1093/ecam/nep120
    • Chao WW, Kuo YH, Hsieh SL, Lin BF. Inhibitory effects of ethyl acetate extract of Andrographis paniculata on NF-κB trans-activation activity and LPS-induced acute inflammation in mice. Evid Based Complement Alternat Med 2009, doi:10.1093/ecam/nep120.
    • (2009) Evid Based Complement Alternat Med
    • Chao, W.W.1    Kuo, Y.H.2    Hsieh, S.L.3    Lin, B.F.4
  • 40
    • 70349558444 scopus 로고    scopus 로고
    • Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals
    • 10.1007/s12272-009-1902-x, 19784573
    • Suebsasana S, Pongnaratorn P, Sattayasai J, Arkaravichien T, Tiamkao S, Aromdee C. Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals. Arch Pharm Res 2009, 32(9):1191-1200. 10.1007/s12272-009-1902-x, 19784573.
    • (2009) Arch Pharm Res , vol.32 , Issue.9 , pp. 1191-1200
    • Suebsasana, S.1    Pongnaratorn, P.2    Sattayasai, J.3    Arkaravichien, T.4    Tiamkao, S.5    Aromdee, C.6
  • 41
    • 2342550564 scopus 로고    scopus 로고
    • Anticancer and immunostimulatory compounds from Andrographis paniculata
    • 10.1016/j.jep.2003.12.009, 15138014
    • Kumar RA, Sridevi K, Kumar NV, Nanduri S, Rajagopal S. Anticancer and immunostimulatory compounds from Andrographis paniculata. J Ethnopharmacol 2004, 92:291-295. 10.1016/j.jep.2003.12.009, 15138014.
    • (2004) J Ethnopharmacol , vol.92 , pp. 291-295
    • Kumar, R.A.1    Sridevi, K.2    Kumar, N.V.3    Nanduri, S.4    Rajagopal, S.5
  • 42
    • 55449109861 scopus 로고    scopus 로고
    • Cytotoxic constituents from Andrographis paniculata induce cell cycle arrest in Jurkat cells
    • 10.1002/ptr.2493, 18546141
    • Geethangili M, Rao YK, Fang SH, Tzeng YM. Cytotoxic constituents from Andrographis paniculata induce cell cycle arrest in Jurkat cells. Phytother Res 2008, 22:1336-1341. 10.1002/ptr.2493, 18546141.
    • (2008) Phytother Res , vol.22 , pp. 1336-1341
    • Geethangili, M.1    Rao, Y.K.2    Fang, S.H.3    Tzeng, Y.M.4
  • 43
    • 34247606683 scopus 로고    scopus 로고
    • Activation of cytotoxic T lymphocyte responses and attenuation of tumor growth in vivo by Andrographis paniculata extract and andrographolide
    • 10.1080/08923970701282726, 17464769
    • Sheeja K, Kuttan G. Activation of cytotoxic T lymphocyte responses and attenuation of tumor growth in vivo by Andrographis paniculata extract and andrographolide. Immunopharmacol Immunotoxicol 2007, 29:81-93. 10.1080/08923970701282726, 17464769.
    • (2007) Immunopharmacol Immunotoxicol , vol.29 , pp. 81-93
    • Sheeja, K.1    Kuttan, G.2
  • 44
    • 45249095614 scopus 로고    scopus 로고
    • Ent-Labdane diterpenoid lactone stereoisomers from Andrographis paniculata
    • 10.1021/np0704452, 18357994
    • Chen L, Zhu H, Wang R, Zhou K, Jing Y, Qiu F. ent-Labdane diterpenoid lactone stereoisomers from Andrographis paniculata. J Nat Prod 2008, 71:852-855. 10.1021/np0704452, 18357994.
    • (2008) J Nat Prod , vol.71 , pp. 852-855
    • Chen, L.1    Zhu, H.2    Wang, R.3    Zhou, K.4    Jing, Y.5    Qiu, F.6
  • 45
    • 0141457852 scopus 로고    scopus 로고
    • Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
    • 10.1046/j.1359-4117.2003.01090.x, 14641821
    • Rajagopal S, Kumar RA, Deevi DS, Satyanarayana C, Rajagopalan R. Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata. J Exp Ther Oncol 2003, 3:147-158. 10.1046/j.1359-4117.2003.01090.x, 14641821.
    • (2003) J Exp Ther Oncol , vol.3 , pp. 147-158
    • Rajagopal, S.1    Kumar, R.A.2    Deevi, D.S.3    Satyanarayana, C.4    Rajagopalan, R.5
  • 46
    • 13144273079 scopus 로고    scopus 로고
    • DRF3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells
    • 10.1186/1471-2407-4-26, 441383, 15207007
    • Satyanarayana C, Deevi DS, Rajagopalan R, Srinivas N, Rajagopal S. DRF3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells. BMC cancer 2004, 4:26-33. 10.1186/1471-2407-4-26, 441383, 15207007.
    • (2004) BMC cancer , vol.4 , pp. 26-33
    • Satyanarayana, C.1    Deevi, D.S.2    Rajagopalan, R.3    Srinivas, N.4    Rajagopal, S.5
  • 48
    • 48849109817 scopus 로고    scopus 로고
    • Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide
    • 10.1016/j.cbi.2008.06.006, 18619950
    • Shi MD, Lin HH, Lee YC, Chao JK, Lin RA, Chen JH. Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide. Chem Biol Interact 2008, 174:201-210. 10.1016/j.cbi.2008.06.006, 18619950.
    • (2008) Chem Biol Interact , vol.174 , pp. 201-210
    • Shi, M.D.1    Lin, H.H.2    Lee, Y.C.3    Chao, J.K.4    Lin, R.A.5    Chen, J.H.6
  • 49
    • 30844438519 scopus 로고    scopus 로고
    • Andrographolide isolated from Andrographis paniculata induces cell cycle arrest and mitochondrial mediated apoptosis in human leukemic HL-60 cells
    • 10.1055/s-2005-873128, 16395645
    • Cheung HY, Cheung SH, Li J, Cheung CS, Lai WP, Fong WF, Leung FM. Andrographolide isolated from Andrographis paniculata induces cell cycle arrest and mitochondrial mediated apoptosis in human leukemic HL-60 cells. Planta Med 2005, 71:1106-1111. 10.1055/s-2005-873128, 16395645.
    • (2005) Planta Med , vol.71 , pp. 1106-1111
    • Cheung, H.Y.1    Cheung, S.H.2    Li, J.3    Cheung, C.S.4    Lai, W.P.5    Fong, W.F.6    Leung, F.M.7
  • 50
    • 36049035359 scopus 로고    scopus 로고
    • Andrographolide inhibits human hepatoma derived Hep3B cell growth through the activation of c-Jun N-terminal kinase
    • 10.1055/s-2007-990230, 17918040
    • Ji L, liu T, Liu J, Chen Y, Wang Z. Andrographolide inhibits human hepatoma derived Hep3B cell growth through the activation of c-Jun N-terminal kinase. Planta Med 2007, 73:1397-1401. 10.1055/s-2007-990230, 17918040.
    • (2007) Planta Med , vol.73 , pp. 1397-1401
    • Ji, L.1    liu, T.2    Liu, J.3    Chen, Y.4    Wang, Z.5
  • 51
    • 58149247982 scopus 로고    scopus 로고
    • Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis
    • 10.1211/jpp.61.01.0010, 19126299
    • Manikam SD, Stanslas J. Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis. J Pharm Pharmacol 2009, 61(1):69-78. 10.1211/jpp.61.01.0010, 19126299.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.1 , pp. 69-78
    • Manikam, S.D.1    Stanslas, J.2
  • 52
    • 33744915312 scopus 로고    scopus 로고
    • Critical role of pro-apoptotic Bcl-2 family members in andrographolide induced apoptosis in human cancer cells
    • 10.1016/j.bcp.2006.04.019, 16740251
    • Zhou J, Zhang S, Ong CN, Shen HM. Critical role of pro-apoptotic Bcl-2 family members in andrographolide induced apoptosis in human cancer cells. Biochem Pharmacol 2006, 72:132-144. 10.1016/j.bcp.2006.04.019, 16740251.
    • (2006) Biochem Pharmacol , vol.72 , pp. 132-144
    • Zhou, J.1    Zhang, S.2    Ong, C.N.3    Shen, H.M.4
  • 53
    • 51049122623 scopus 로고    scopus 로고
    • Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53 mediated beath receptor 4 up-regulation
    • 10.1158/1535-7163.MCT-08-0071, 18645026
    • Zhou J, Lu GD, Ong CS, Ong CN, Shen HM. Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53 mediated beath receptor 4 up-regulation. Mol Cancer Ther 2008, 7(7):2170-2180. 10.1158/1535-7163.MCT-08-0071, 18645026.
    • (2008) Mol Cancer Ther , vol.7 , Issue.7 , pp. 2170-2180
    • Zhou, J.1    Lu, G.D.2    Ong, C.S.3    Ong, C.N.4    Shen, H.M.5
  • 54
    • 60849083797 scopus 로고    scopus 로고
    • Andrographolide enhances 5-fluorouracil induced apoptosis via caspase 8 dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells
    • 10.1016/j.canlet.2008.11.015, 19097688
    • Yang L, Wu D, Luo K, Wu S, Wu P. Andrographolide enhances 5-fluorouracil induced apoptosis via caspase 8 dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells. Cancer Lett 2009, 276:180-188. 10.1016/j.canlet.2008.11.015, 19097688.
    • (2009) Cancer Lett , vol.276 , pp. 180-188
    • Yang, L.1    Wu, D.2    Luo, K.3    Wu, S.4    Wu, P.5
  • 55
    • 41949109020 scopus 로고    scopus 로고
    • Suppression of v-Src transformation by andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway
    • 10.1074/jbc.M705877200, 18086662
    • Liang FP, Lin CH, Kuo CD, Chao HP, Fu SL. Suppression of v-Src transformation by andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway. J Biol Chem 2008, 283(8):5023-5033. 10.1074/jbc.M705877200, 18086662.
    • (2008) J Biol Chem , vol.283 , Issue.8 , pp. 5023-5033
    • Liang, F.P.1    Lin, C.H.2    Kuo, C.D.3    Chao, H.P.4    Fu, S.L.5
  • 56
    • 33845936572 scopus 로고    scopus 로고
    • Antiangiogenic activity of Andrographis paniculata extract and andrographolide
    • 10.1016/j.intimp.2006.10.002, 17178389
    • Sheeja K, Guruvayoorappan C, Kuttan G. Antiangiogenic activity of Andrographis paniculata extract and andrographolide. Int Immunopharmacol 2007, 7:211-221. 10.1016/j.intimp.2006.10.002, 17178389.
    • (2007) Int Immunopharmacol , vol.7 , pp. 211-221
    • Sheeja, K.1    Guruvayoorappan, C.2    Kuttan, G.3
  • 57
    • 34547772727 scopus 로고    scopus 로고
    • Andrographolide inhibits the adhesion of gastric cancer cells to endothelial cells by blocking E-selectin expression
    • Jiang CG, Li JB, Liu FR, Wu T, Xu HM. Andrographolide inhibits the adhesion of gastric cancer cells to endothelial cells by blocking E-selectin expression. Anticancer Res 2007, 27:2439-2448.
    • (2007) Anticancer Res , vol.27 , pp. 2439-2448
    • Jiang, C.G.1    Li, J.B.2    Liu, F.R.3    Wu, T.4    Xu, H.M.5
  • 58
    • 67349194249 scopus 로고    scopus 로고
    • Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down regulation of MMP-7 expression
    • 10.1016/j.cbi.2009.04.011, 19426720
    • Shi MD, Lin HH, Chiang TA, Tsai LY, Tsai SM, Lee YC, Chen JH. Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down regulation of MMP-7 expression. Chem Biol Interact 2009, 180:344-352. 10.1016/j.cbi.2009.04.011, 19426720.
    • (2009) Chem Biol Interact , vol.180 , pp. 344-352
    • Shi, M.D.1    Lin, H.H.2    Chiang, T.A.3    Tsai, L.Y.4    Tsai, S.M.5    Lee, Y.C.6    Chen, J.H.7
  • 59
    • 77349091801 scopus 로고    scopus 로고
    • Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signalling pathway
    • 10.1016/j.ejphar.2010.01.009, 20097193
    • Lee YC, Lin HH, Hsu CH, Wang CJ, Chiang TA, Chen JH. Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signalling pathway. Eur J Pharmacol 2010, 632(1-3):23-32. 10.1016/j.ejphar.2010.01.009, 20097193.
    • (2010) Eur J Pharmacol , vol.632 , Issue.1-3 , pp. 23-32
    • Lee, Y.C.1    Lin, H.H.2    Hsu, C.H.3    Wang, C.J.4    Chiang, T.A.5    Chen, J.H.6
  • 62
    • 54949147613 scopus 로고    scopus 로고
    • Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis
    • 10.1038/bjp.2008.368, 2584933, 18806812
    • Jada SR, Matthews C, Saad MS, Hamzah AS, Lajis NH, Stevens MFG, Stanslas J. Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis. Br J Pharmacol 2008, 155:641-654. 10.1038/bjp.2008.368, 2584933, 18806812.
    • (2008) Br J Pharmacol , vol.155 , pp. 641-654
    • Jada, S.R.1    Matthews, C.2    Saad, M.S.3    Hamzah, A.S.4    Lajis, N.H.5    Stevens, M.F.G.6    Stanslas, J.7
  • 63
    • 77649184264 scopus 로고    scopus 로고
    • Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemo-sensitivity of cancer cells to doxorubicin
    • 10.1016/j.bcp.2009.12.014, 20026083
    • Zhou J, Ong CN, Hur GM, Shen HM. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemo-sensitivity of cancer cells to doxorubicin. Biochem Pharmacol 2010, 79(9):1242-1250. 10.1016/j.bcp.2009.12.014, 20026083.
    • (2010) Biochem Pharmacol , vol.79 , Issue.9 , pp. 1242-1250
    • Zhou, J.1    Ong, C.N.2    Hur, G.M.3    Shen, H.M.4
  • 64
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subset: Th1, Th2 and more
    • 10.1016/0167-5699(96)80606-2, 8820272
    • Mosmann TR, Sad S. The expanding universe of T-cell subset: Th1, Th2 and more. Immunol Today 1996, 17:138-146. 10.1016/0167-5699(96)80606-2, 8820272.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 65
    • 33846997577 scopus 로고    scopus 로고
    • Modulation of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by andrographolide in normal and Ehrlich ascites carcinoma-bearing mice
    • 10.1177/1534735406298975, 17351028
    • Sheeja K, Kuttan G. Modulation of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by andrographolide in normal and Ehrlich ascites carcinoma-bearing mice. Integr Cancer Ther 2007, 6(1):66-73. 10.1177/1534735406298975, 17351028.
    • (2007) Integr Cancer Ther , vol.6 , Issue.1 , pp. 66-73
    • Sheeja, K.1    Kuttan, G.2
  • 66
    • 20544471699 scopus 로고    scopus 로고
    • Andrographolide inhibits IFN-gamma and IL-2 cytokine production and protects against cell apoptosis
    • 10.1055/s-2005-864138, 15931581
    • Burgos RA, Seguel K, Perez M, Meneses A, Ortega M, Guarda MI, Loaiza A, Hancke JL. Andrographolide inhibits IFN-gamma and IL-2 cytokine production and protects against cell apoptosis. Planta Med 2005, 71(5):429-434. 10.1055/s-2005-864138, 15931581.
    • (2005) Planta Med , vol.71 , Issue.5 , pp. 429-434
    • Burgos, R.A.1    Seguel, K.2    Perez, M.3    Meneses, A.4    Ortega, M.5    Guarda, M.I.6    Loaiza, A.7    Hancke, J.L.8
  • 67
    • 58149159571 scopus 로고    scopus 로고
    • Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation
    • 10.1016/j.ejphar.2008.11.011, 19038244
    • Carretta MD, Alarcon P, Jara E, Solis L, Hancke JL, Concha II, Hidalgo MA, Burgos RA. Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation. Eur J Pharmacol 2009, 602:413-421. 10.1016/j.ejphar.2008.11.011, 19038244.
    • (2009) Eur J Pharmacol , vol.602 , pp. 413-421
    • Carretta, M.D.1    Alarcon, P.2    Jara, E.3    Solis, L.4    Hancke, J.L.5    Concha, I.I.6    Hidalgo, M.A.7    Burgos, R.A.8
  • 69
    • 70350786933 scopus 로고    scopus 로고
    • Inhibition of NF-κB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide
    • 10.1038/cmi.2009.49, 19887051
    • Li J, Luo L, Wang X, Liao B, Li G. Inhibition of NF-κB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide. Cell Mol Immunol 2009, 6(5):381-385. 10.1038/cmi.2009.49, 19887051.
    • (2009) Cell Mol Immunol , vol.6 , Issue.5 , pp. 381-385
    • Li, J.1    Luo, L.2    Wang, X.3    Liao, B.4    Li, G.5
  • 70
    • 1342323332 scopus 로고    scopus 로고
    • Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation
    • 10.1124/jpet.103.059683, 14718612
    • Wang T, Liu B, Zhang W, Wilson B, Hong JS. Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation. J Pharmacol Exp Ther 2004, 308:975-983. 10.1124/jpet.103.059683, 14718612.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 975-983
    • Wang, T.1    Liu, B.2    Zhang, W.3    Wilson, B.4    Hong, J.S.5
  • 71
    • 65249122527 scopus 로고    scopus 로고
    • A novel anti-inflammatory role for andrographolide in asthma via inhibition of the nuclear factor-κB pathway
    • 10.1164/rccm.200809-1516OC, 19201922
    • Bao Z, Guan S, Cheng C, Wu S, Wong SH, Kemeny DM, Leung BP, Wong WSF. A novel anti-inflammatory role for andrographolide in asthma via inhibition of the nuclear factor-κB pathway. Am J Respir Crit Care Med 2009, 179:657-665. 10.1164/rccm.200809-1516OC, 19201922.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 657-665
    • Bao, Z.1    Guan, S.2    Cheng, C.3    Wu, S.4    Wong, S.H.5    Kemeny, D.M.6    Leung, B.P.7    Wong, W.S.F.8
  • 72
    • 60249088269 scopus 로고    scopus 로고
    • In vitro and in vivo anti-inflammatory effects of andrographolide
    • 10.1016/j.intimp.2008.12.002, 19110075
    • Abu-Ghefreh AA, Canatan H, Ezeamuzie CI. In vitro and in vivo anti-inflammatory effects of andrographolide. Int Immunopharmacol 2009, 9:313-318. 10.1016/j.intimp.2008.12.002, 19110075.
    • (2009) Int Immunopharmacol , vol.9 , pp. 313-318
    • Abu-Ghefreh, A.A.1    Canatan, H.2    Ezeamuzie, C.I.3
  • 73
    • 67849121334 scopus 로고    scopus 로고
    • Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo controlled trial
    • 10.1007/s10067-009-1180-5, 19408036
    • Burgos RA, Hancke JL, Bertoglio JC, Aguirre V, Arriagada S, Calvo M, Caceres DD. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo controlled trial. Clin Rheumatol 2009, 28:931-946. 10.1007/s10067-009-1180-5, 19408036.
    • (2009) Clin Rheumatol , vol.28 , pp. 931-946
    • Burgos, R.A.1    Hancke, J.L.2    Bertoglio, J.C.3    Aguirre, V.4    Arriagada, S.5    Calvo, M.6    Caceres, D.D.7
  • 74
    • 0027295862 scopus 로고
    • Immunostimulant agents from Andrographis paniculata
    • 10.1021/np50097a002, 8377022
    • Puri A, Saxena R, Saxena RP, Saxena KC, Srivastava V, Tandon JS. Immunostimulant agents from Andrographis paniculata. J Nat Prod 1993, 56(7):995-999. 10.1021/np50097a002, 8377022.
    • (1993) J Nat Prod , vol.56 , Issue.7 , pp. 995-999
    • Puri, A.1    Saxena, R.2    Saxena, R.P.3    Saxena, K.C.4    Srivastava, V.5    Tandon, J.S.6
  • 75
    • 0036813343 scopus 로고    scopus 로고
    • Effect of andrographolide and Kan Jang--fixed combination of extract SHA-10 and extract SHE-3 on proliferation of human lymphocytes, production of cytokines and immune activation markers in the whole blood cells culture
    • 10.1078/094471102321616409, 12487323
    • Panossian A, Davtyan T, Gukassyan N, Gukasova G, Mamikonyan G, Gabrielian E, Wikman G. Effect of andrographolide and Kan Jang--fixed combination of extract SHA-10 and extract SHE-3 on proliferation of human lymphocytes, production of cytokines and immune activation markers in the whole blood cells culture. Phytomedicine 2002, 9(7):598-605. 10.1078/094471102321616409, 12487323.
    • (2002) Phytomedicine , vol.9 , Issue.7 , pp. 598-605
    • Panossian, A.1    Davtyan, T.2    Gukassyan, N.3    Gukasova, G.4    Mamikonyan, G.5    Gabrielian, E.6    Wikman, G.7
  • 76
    • 33847014869 scopus 로고    scopus 로고
    • Modulation of immune response in mice immunized with an inactivated Salmonella vaccine and gavaged with Andrographis paniculata extract or andrographolide
    • 10.1016/j.intimp.2006.12.008, 17321475
    • Xu Y, Chen A, Fry S, Barrow RA, Marshall RL, Mukkur TKS. Modulation of immune response in mice immunized with an inactivated Salmonella vaccine and gavaged with Andrographis paniculata extract or andrographolide. Int Immunopharmacol 2007, 7:515-5238. 10.1016/j.intimp.2006.12.008, 17321475.
    • (2007) Int Immunopharmacol , vol.7 , pp. 515-5238
    • Xu, Y.1    Chen, A.2    Fry, S.3    Barrow, R.A.4    Marshall, R.L.5    Mukkur, T.K.S.6
  • 77
    • 69149093345 scopus 로고    scopus 로고
    • Evaluation of immunomodulatory activity of an extract of Andrographolides from Andrographis paniculata
    • 10.1055/s-0029-1185398, 19263340
    • Naik SR, Hule A. Evaluation of immunomodulatory activity of an extract of Andrographolides from Andrographis paniculata. Planta Med 2009, 75:785-791. 10.1055/s-0029-1185398, 19263340.
    • (2009) Planta Med , vol.75 , pp. 785-791
    • Naik, S.R.1    Hule, A.2
  • 78
    • 0023912917 scopus 로고
    • Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese medicinal herbs
    • 10.1016/0166-3542(88)90001-0, 2840849
    • Chang RS, Yeung HW. Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese medicinal herbs. Antiviral Res 1988, 9:163-176. 10.1016/0166-3542(88)90001-0, 2840849.
    • (1988) Antiviral Res , vol.9 , pp. 163-176
    • Chang, R.S.1    Yeung, H.W.2
  • 80
    • 0033846074 scopus 로고    scopus 로고
    • A phase I trial of andrographolide in HIV positive patients and normal volunteers
    • 10.1002/1099-1573(200008)14:5<333::AID-PTR584>3.0.CO;2-D, 10925397
    • Calabrese C, Berman SH, Babish JG, Ma X, Shinto L, Dorr M, Well K, Wenner CA, Standish LJ. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 2000, 14:333-338. 10.1002/1099-1573(200008)14:5<333::AID-PTR584>3.0.CO;2-D, 10925397.
    • (2000) Phytother Res , vol.14 , pp. 333-338
    • Calabrese, C.1    Berman, S.H.2    Babish, J.G.3    Ma, X.4    Shinto, L.5    Dorr, M.6    Well, K.7    Wenner, C.A.8    Standish, L.J.9
  • 81
    • 31144431583 scopus 로고    scopus 로고
    • Antiviral properties of ent-labdene diterpenes of Andrographis paniculata Nees, inhibitors of herpes simplex virus type I
    • 10.1002/ptr.1765, 16372376
    • Wiart C, Kumar K, Yusof MY, Hamimah H, Fauzi ZM, Sulaiman M. Antiviral properties of ent-labdene diterpenes of Andrographis paniculata Nees, inhibitors of herpes simplex virus type I. Phytother Res 2005, 19:1069-1070. 10.1002/ptr.1765, 16372376.
    • (2005) Phytother Res , vol.19 , pp. 1069-1070
    • Wiart, C.1    Kumar, K.2    Yusof, M.Y.3    Hamimah, H.4    Fauzi, Z.M.5    Sulaiman, M.6
  • 82
    • 55549135380 scopus 로고    scopus 로고
    • Inhibition of the Epstein-barr virus lytic cycle by andrographolide
    • 10.1248/bpb.31.2018, 18981566
    • Lin TP, Chen SY, Duh PD, Chang LK, Liu YN. Inhibition of the Epstein-barr virus lytic cycle by andrographolide. Biol Pharm Bull 2008, 31(11):2018-2023. 10.1248/bpb.31.2018, 18981566.
    • (2008) Biol Pharm Bull , vol.31 , Issue.11 , pp. 2018-2023
    • Lin, T.P.1    Chen, S.Y.2    Duh, P.D.3    Chang, L.K.4    Liu, Y.N.5
  • 83
    • 69149103489 scopus 로고    scopus 로고
    • Activity of andrographolide and its derivatives against influenza virus in vivo and in vitro
    • 10.1248/bpb.32.1385, 19652378
    • Chen JX, Xue HJ, Ye WC, Fang BH, Liu YH, Yuan SH, Yu P, Wang YQ. Activity of andrographolide and its derivatives against influenza virus in vivo and in vitro. Biol Pharm Bull 2009, 32(8):1385-1391. 10.1248/bpb.32.1385, 19652378.
    • (2009) Biol Pharm Bull , vol.32 , Issue.8 , pp. 1385-1391
    • Chen, J.X.1    Xue, H.J.2    Ye, W.C.3    Fang, B.H.4    Liu, Y.H.5    Yuan, S.H.6    Yu, P.7    Wang, Y.Q.8
  • 84
    • 67349136453 scopus 로고    scopus 로고
    • Synthesis and evaluation of antibacterial activities of andrographolide analogues
    • 10.1016/j.ejmech.2008.12.014, 19152987
    • Jiang X, Yu P, Jiang J, Zhang Z, Wang Z, Yang Z, Tian Z, Wright SC, Larrick JW, Wang Y. Synthesis and evaluation of antibacterial activities of andrographolide analogues. Eur J Med Chem 2009, 44:2936-2943. 10.1016/j.ejmech.2008.12.014, 19152987.
    • (2009) Eur J Med Chem , vol.44 , pp. 2936-2943
    • Jiang, X.1    Yu, P.2    Jiang, J.3    Zhang, Z.4    Wang, Z.5    Yang, Z.6    Tian, Z.7    Wright, S.C.8    Larrick, J.W.9    Wang, Y.10
  • 85
    • 0036812633 scopus 로고    scopus 로고
    • A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis
    • Gabrielian ES, Shukarian AK, Goukasova GI, Chandanian GL, Panossian AG, Wikman G, Wagner H. A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis. Phytomedicine 2000, 9(7):589-597.
    • (2000) Phytomedicine , vol.9 , Issue.7 , pp. 589-597
    • Gabrielian, E.S.1    Shukarian, A.K.2    Goukasova, G.I.3    Chandanian, G.L.4    Panossian, A.G.5    Wikman, G.6    Wagner, H.7
  • 86
    • 33747376146 scopus 로고    scopus 로고
    • The effect of medicinal plants used in Chinese folk medicine on RANTES secretion by virus infected human epithelial cells
    • 10.1016/j.jep.2006.03.004, 16621378
    • Ko HC, Wei BL, Chiou WF. The effect of medicinal plants used in Chinese folk medicine on RANTES secretion by virus infected human epithelial cells. J Ethnopharmacol 2006, 107:205-210. 10.1016/j.jep.2006.03.004, 16621378.
    • (2006) J Ethnopharmacol , vol.107 , pp. 205-210
    • Ko, H.C.1    Wei, B.L.2    Chiou, W.F.3
  • 87
    • 26444463455 scopus 로고    scopus 로고
    • Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1α-induced leukocytes chemotaxis
    • 10.1002/jcb.20464, 15937916
    • Ji LL, Wang Z, Dong F, Zhang WB, Wang ZT. Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1α-induced leukocytes chemotaxis. J Cell Biochem 2005, 95:970-978. 10.1002/jcb.20464, 15937916.
    • (2005) J Cell Biochem , vol.95 , pp. 970-978
    • Ji, L.L.1    Wang, Z.2    Dong, F.3    Zhang, W.B.4    Wang, Z.T.5
  • 88
    • 0033557956 scopus 로고    scopus 로고
    • Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters
    • 10.1042/0264-6021:3380107, 1220031, 9931305
    • Basak A, Cooper S, Roberge AG, Banik UK, Chretien M, Seidah NG. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J 1999, 338:107-113. 10.1042/0264-6021:3380107, 1220031, 9931305.
    • (1999) Biochem J , vol.338 , pp. 107-113
    • Basak, A.1    Cooper, S.2    Roberge, A.G.3    Banik, U.K.4    Chretien, M.5    Seidah, N.G.6
  • 89
    • 0025911006 scopus 로고
    • Dehydroandrographolide succinic acid monoester as an inhibitor against the human immunodeficiency virus
    • Chang RS, Ding L, Chen GQ, Pan QC, Zhao ZL, Smith KM. Dehydroandrographolide succinic acid monoester as an inhibitor against the human immunodeficiency virus. Proc Soc Exp Biol Med 1991, 197(1):59-66.
    • (1991) Proc Soc Exp Biol Med , vol.197 , Issue.1 , pp. 59-66
    • Chang, R.S.1    Ding, L.2    Chen, G.Q.3    Pan, Q.C.4    Zhao, Z.L.5    Smith, K.M.6
  • 90
    • 33947607132 scopus 로고    scopus 로고
    • Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol induced toxicity in mice
    • 10.1016/j.jep.2006.10.026, 17127022
    • Singha PK, Roy S, Dey S. Protective activity of andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol induced toxicity in mice. J Ethnopharmacol 2007, 111:13-21. 10.1016/j.jep.2006.10.026, 17127022.
    • (2007) J Ethnopharmacol , vol.111 , pp. 13-21
    • Singha, P.K.1    Roy, S.2    Dey, S.3
  • 91
    • 0027337678 scopus 로고
    • Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata
    • 10.1016/0006-2952(93)90364-3, 8347130
    • Kapil A, Koul IB, Banerjee SK, Gupta BD. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol 1993, 46(1):182-185. 10.1016/0006-2952(93)90364-3, 8347130.
    • (1993) Biochem Pharmacol , vol.46 , Issue.1 , pp. 182-185
    • Kapil, A.1    Koul, I.B.2    Banerjee, S.K.3    Gupta, B.D.4
  • 92
    • 58149202134 scopus 로고    scopus 로고
    • In vitro nitotine induced superoxide mediated DNA fragmentation in lymphocytes: protective role of Andrographis paniculata Nees
    • 10.1016/j.tiv.2008.10.012, 19027060
    • Das S, Neogy S, Gautam N, Roy S. In vitro nitotine induced superoxide mediated DNA fragmentation in lymphocytes: protective role of Andrographis paniculata Nees. Toxicol in Vitro 2009, 23:90-98. 10.1016/j.tiv.2008.10.012, 19027060.
    • (2009) Toxicol in Vitro , vol.23 , pp. 90-98
    • Das, S.1    Neogy, S.2    Gautam, N.3    Roy, S.4
  • 93
    • 66149088090 scopus 로고    scopus 로고
    • Oxidative stress in the brain of nicotine induced toxicity: protective role of Andrographis paniculata Nees and vitamin E
    • Das S, Gautam N, Dey SK, Maiti T, Roy S. Oxidative stress in the brain of nicotine induced toxicity: protective role of Andrographis paniculata Nees and vitamin E. Appl Physiol Nutr Metab 2009, 34:125-135.
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 125-135
    • Das, S.1    Gautam, N.2    Dey, S.K.3    Maiti, T.4    Roy, S.5
  • 94
    • 67949104872 scopus 로고    scopus 로고
    • Absorption of andrographolides from Andrographis paniculata and its effect on CCl(4)-induced oxidative stress in rats
    • 10.1016/j.fct.2009.06.022, 19540299
    • Akowuah GA, Zhari I, Mariam A, Yam MF. Absorption of andrographolides from Andrographis paniculata and its effect on CCl(4)-induced oxidative stress in rats. Food Chem Toxicol 2009, 47(9):2321-2326. 10.1016/j.fct.2009.06.022, 19540299.
    • (2009) Food Chem Toxicol , vol.47 , Issue.9 , pp. 2321-2326
    • Akowuah, G.A.1    Zhari, I.2    Mariam, A.3    Yam, M.F.4
  • 95
    • 34848886331 scopus 로고    scopus 로고
    • Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes
    • 10.1016/j.taap.2007.07.008, 17825862
    • Jaruchotikamol A, Jarukamiorn K, Sirisangtrakul W, Sakuma T, Kawasaki Y, Nemoto N. Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes. Toxicol Appl Pharmacol 2007, 224:156-162. 10.1016/j.taap.2007.07.008, 17825862.
    • (2007) Toxicol Appl Pharmacol , vol.224 , pp. 156-162
    • Jaruchotikamol, A.1    Jarukamiorn, K.2    Sirisangtrakul, W.3    Sakuma, T.4    Kawasaki, Y.5    Nemoto, N.6
  • 96
    • 70350134715 scopus 로고    scopus 로고
    • Synergistic increases of metabolism and oxidation reduction genes on their expression after combined treatment with a CYP1A inducer and andrographolide
    • 10.1016/j.cbi.2009.09.001, 19737545
    • Chatuphonprasert W, Jarukamjorn K, Kondo S, Nemoto N. Synergistic increases of metabolism and oxidation reduction genes on their expression after combined treatment with a CYP1A inducer and andrographolide. Chem Biol Interact 2009, 182:233-238. 10.1016/j.cbi.2009.09.001, 19737545.
    • (2009) Chem Biol Interact , vol.182 , pp. 233-238
    • Chatuphonprasert, W.1    Jarukamjorn, K.2    Kondo, S.3    Nemoto, N.4
  • 97
    • 37449013831 scopus 로고    scopus 로고
    • Differential iknhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide
    • 10.1016/j.jep.2007.10.013, 18053665
    • Pekthong D, Martin H, Abadie C, Bonet A, Heyd B, Mantion G, Richert L. Differential iknhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide. J Ethnopharmacol 2008, 115:432-440. 10.1016/j.jep.2007.10.013, 18053665.
    • (2008) J Ethnopharmacol , vol.115 , pp. 432-440
    • Pekthong, D.1    Martin, H.2    Abadie, C.3    Bonet, A.4    Heyd, B.5    Mantion, G.6    Richert, L.7
  • 98
    • 62749197576 scopus 로고    scopus 로고
    • Effects of Andrographis paniculata extract and andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures
    • 10.1016/j.cbi.2008.10.054, 19041297
    • Pekthong D, Blanchard N, Abadie C, Bonet A, Heyd B, Mantion G, Berthelot A, Richert L, Martin H. Effects of Andrographis paniculata extract and andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures. Chem Biol Interact 2009, 179:247-255. 10.1016/j.cbi.2008.10.054, 19041297.
    • (2009) Chem Biol Interact , vol.179 , pp. 247-255
    • Pekthong, D.1    Blanchard, N.2    Abadie, C.3    Bonet, A.4    Heyd, B.5    Mantion, G.6    Berthelot, A.7    Richert, L.8    Martin, H.9
  • 99
    • 38649140692 scopus 로고    scopus 로고
    • Modulation of the expression of the π class of glutathione S-transferase by Andrographis paniculata extracts and andrographolide
    • 10.1016/j.fct.2007.11.002, 18082303
    • Chang KT, Lii CK, Tsai CW, Yang AJ, Chen HW. Modulation of the expression of the π class of glutathione S-transferase by Andrographis paniculata extracts and andrographolide. Food Chem Toxicol 2008, 46:1079-1088. 10.1016/j.fct.2007.11.002, 18082303.
    • (2008) Food Chem Toxicol , vol.46 , pp. 1079-1088
    • Chang, K.T.1    Lii, C.K.2    Tsai, C.W.3    Yang, A.J.4    Chen, H.W.5
  • 100
    • 76449089803 scopus 로고    scopus 로고
    • Activation of the cAMP/CREB/inducible cAMP early repressor pathway suppresses andrographolide-induced gene expression of the π class of glutathione S-transferase in rat primary hepatocytes
    • 10.1021/jf902221j, 20063885
    • Yang AJ, Li CC, Lu CY, Liu KL, Tsai CW, Lii CK, Chen HW. Activation of the cAMP/CREB/inducible cAMP early repressor pathway suppresses andrographolide-induced gene expression of the π class of glutathione S-transferase in rat primary hepatocytes. J Agric Food Chem 2010, 58:1993-2000. 10.1021/jf902221j, 20063885.
    • (2010) J Agric Food Chem , vol.58 , pp. 1993-2000
    • Yang, A.J.1    Li, C.C.2    Lu, C.Y.3    Liu, K.L.4    Tsai, C.W.5    Lii, C.K.6    Chen, H.W.7
  • 101
    • 0029852445 scopus 로고    scopus 로고
    • Hypotensive activity of aqueous extract of Andrographis paniculata in rats
    • 10.1111/j.1440-1681.1996.tb01756.x, 8886488
    • Zhang CY, Tan BK. Hypotensive activity of aqueous extract of Andrographis paniculata in rats. Clin Exp Pharmacol Physiol 1996, 23:675-678. 10.1111/j.1440-1681.1996.tb01756.x, 8886488.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 675-678
    • Zhang, C.Y.1    Tan, B.K.2
  • 102
    • 0030996843 scopus 로고    scopus 로고
    • Mechanism of cardiovascular acrivity of Andrographis paniculata in the anaesthetized rat
    • 10.1016/S0378-8741(97)01509-2, 9174969
    • Zhang CY, Tan BK. Mechanism of cardiovascular acrivity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmacol 1997, 56:97-101. 10.1016/S0378-8741(97)01509-2, 9174969.
    • (1997) J Ethnopharmacol , vol.56 , pp. 97-101
    • Zhang, C.Y.1    Tan, B.K.2
  • 103
    • 0031862598 scopus 로고    scopus 로고
    • Vasorelaxation of rat thoracic aorta caused by 14-deoxyandrographolide
    • 10.1111/j.1440-1681.1998.tb02226.x, 9673817
    • Zhang CY, Tan BK. Vasorelaxation of rat thoracic aorta caused by 14-deoxyandrographolide. Clin Exp Pharmacol Physiol 1998, 25:424-429. 10.1111/j.1440-1681.1998.tb02226.x, 9673817.
    • (1998) Clin Exp Pharmacol Physiol , vol.25 , pp. 424-429
    • Zhang, C.Y.1    Tan, B.K.2
  • 104
    • 0032409020 scopus 로고    scopus 로고
    • Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetized rat and isolated right atria
    • 10.1006/phrs.1998.0373, 9990649
    • Zhang C, Kuroyangi M, Tan BK. Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetized rat and isolated right atria. Pharmacol Res 1998, 38(6):413-417. 10.1006/phrs.1998.0373, 9990649.
    • (1998) Pharmacol Res , vol.38 , Issue.6 , pp. 413-417
    • Zhang, C.1    Kuroyangi, M.2    Tan, B.K.3
  • 105
    • 0032992429 scopus 로고    scopus 로고
    • Effects of 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide on nitric oxide production in cultured human endothelial cells
    • 10.1002/(SICI)1099-1573(199903)13:2<157::AID-PTR388>3.0.CO;2-B, 10190192
    • Zhang CY, Tan BK. Effects of 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide on nitric oxide production in cultured human endothelial cells. Phytother Res 1999, 13:157-159. 10.1002/(SICI)1099-1573(199903)13:2<157::AID-PTR388>3.0.CO;2-B, 10190192.
    • (1999) Phytother Res , vol.13 , pp. 157-159
    • Zhang, C.Y.1    Tan, B.K.2
  • 106
    • 0242268444 scopus 로고    scopus 로고
    • Effects of 14-deoxyandrographolide on calcium mediated rat uterine smooth muscle vontractility
    • 10.1002/ptr.1275, 14595578
    • Burgos RA, Loyola M, Hidalgo MA, Labranche TP, Hancke JL. Effects of 14-deoxyandrographolide on calcium mediated rat uterine smooth muscle vontractility. Phytother Res 2003, 17:1011-1015. 10.1002/ptr.1275, 14595578.
    • (2003) Phytother Res , vol.17 , pp. 1011-1015
    • Burgos, R.A.1    Loyola, M.2    Hidalgo, M.A.3    Labranche, T.P.4    Hancke, J.L.5
  • 107
    • 34250887685 scopus 로고    scopus 로고
    • Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts
    • 10.1055/s-2007-967181, 17650544
    • Yoopan N, Thisoda P, Rangkadilok N, Sahasitiwat S, Pholphana N, Ruchirawat S. Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts. Planta Med 2007, 73:503-511. 10.1055/s-2007-967181, 17650544.
    • (2007) Planta Med , vol.73 , pp. 503-511
    • Yoopan, N.1    Thisoda, P.2    Rangkadilok, N.3    Sahasitiwat, S.4    Pholphana, N.5    Ruchirawat, S.6
  • 108
    • 1542345739 scopus 로고    scopus 로고
    • Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway
    • 10.1016/j.bcp.2003.12.015, 15013849
    • Chen JH, Hsiao G, Lee AR, Wu CC, Yen MH. Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway. Biochem Pharmacol 2004, 67:1337-1345. 10.1016/j.bcp.2003.12.015, 15013849.
    • (2004) Biochem Pharmacol , vol.67 , pp. 1337-1345
    • Chen, J.H.1    Hsiao, G.2    Lee, A.R.3    Wu, C.C.4    Yen, M.H.5
  • 109
    • 33751272143 scopus 로고    scopus 로고
    • Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation
    • 10.1016/j.ejphar.2006.09.052, 17081514
    • Thisoda P, Rangkadilok N, Pholphana N, Worasuttayangkurn L, Ruchirawat S, Satayavivad J. Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation. Eur J Pharmacol 2006, 553:39-45. 10.1016/j.ejphar.2006.09.052, 17081514.
    • (2006) Eur J Pharmacol , vol.553 , pp. 39-45
    • Thisoda, P.1    Rangkadilok, N.2    Pholphana, N.3    Worasuttayangkurn, L.4    Ruchirawat, S.5    Satayavivad, J.6
  • 110
    • 36849007402 scopus 로고    scopus 로고
    • Flavonoids and ent-labdane diterpenoids from Andrographis paniculata and their antiplatelet aggregatory and vasorelaxing effects
    • 10.1080/10286020701273627, 18058376
    • Wu TS, Chern HJ, Damu AG, Kuo PC, Su CR, Lee EJ, Teng CM. Flavonoids and ent-labdane diterpenoids from Andrographis paniculata and their antiplatelet aggregatory and vasorelaxing effects. J Asian Nat Prod Res 2008, 10(1-2):17-24. 10.1080/10286020701273627, 18058376.
    • (2008) J Asian Nat Prod Res , vol.10 , Issue.1-2 , pp. 17-24
    • Wu, T.S.1    Chern, H.J.2    Damu, A.G.3    Kuo, P.C.4    Su, C.R.5    Lee, E.J.6    Teng, C.M.7
  • 111
    • 67650270881 scopus 로고    scopus 로고
    • Hypoglycemic herbs and their action mechanisms
    • 10.1186/1749-8546-4-11, 2704217, 19523223
    • Hui H, Tang G, Go VLW. Hypoglycemic herbs and their action mechanisms. Chin Med 2009, 4:11-14. 10.1186/1749-8546-4-11, 2704217, 19523223.
    • (2009) Chin Med , vol.4 , pp. 11-14
    • Hui, H.1    Tang, G.2    Go, V.L.W.3
  • 112
    • 0034531909 scopus 로고    scopus 로고
    • Anti-diabetic property of ethanolic extract of Andrographis paniculata in streptozotocin-diabetic rats
    • Zhang XF, Tan BK. Anti-diabetic property of ethanolic extract of Andrographis paniculata in streptozotocin-diabetic rats. Acta Pharmacol Sin 2000, 21(12):1157-1164.
    • (2000) Acta Pharmacol Sin , vol.21 , Issue.12 , pp. 1157-1164
    • Zhang, X.F.1    Tan, B.K.2
  • 113
    • 0034073761 scopus 로고    scopus 로고
    • Antihyperglycaemic and anti-oxidant properties of Andrographis paniculata in normal and diabetic rats
    • 10.1046/j.1440-1681.2000.03253.x, 10831236
    • Zhang XF, Tan BK. Antihyperglycaemic and anti-oxidant properties of Andrographis paniculata in normal and diabetic rats. Clin Exp Pharmacol Physiol 2000, 27:358-363. 10.1046/j.1440-1681.2000.03253.x, 10831236.
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 358-363
    • Zhang, X.F.1    Tan, B.K.2
  • 114
    • 46749119448 scopus 로고    scopus 로고
    • In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide
    • Subramanian R, Asmawi MZ, Sadikun A. In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. Acta Biochim Pol 2008, 55(2):391-398.
    • (2008) Acta Biochim Pol , vol.55 , Issue.2 , pp. 391-398
    • Subramanian, R.1    Asmawi, M.Z.2    Sadikun, A.3
  • 115
    • 7044227563 scopus 로고    scopus 로고
    • Screening for antihyperglycaemic activity in several local herbs of Malaysia
    • 10.1016/j.jep.2004.07.004, 15507337
    • Husen R, Pihie AH, Nallappan M. Screening for antihyperglycaemic activity in several local herbs of Malaysia. J Ethnopharmacol 2004, 95(2-3):205-208. 10.1016/j.jep.2004.07.004, 15507337.
    • (2004) J Ethnopharmacol , vol.95 , Issue.2-3 , pp. 205-208
    • Husen, R.1    Pihie, A.H.2    Nallappan, M.3
  • 116
    • 33645311509 scopus 로고    scopus 로고
    • Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats
    • 10.1016/j.jep.2005.10.018, 16298503
    • Reyes BA, Bautista ND, Tanquilut NC, Anunciado RV, Leung AB, Sanchez GC, Magtoto RL, Castronuevo P, Tsukamura H, Maeda KI. Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats. J Ethnopharmacol 2006, 105(1-2):196-200. 10.1016/j.jep.2005.10.018, 16298503.
    • (2006) J Ethnopharmacol , vol.105 , Issue.1-2 , pp. 196-200
    • Reyes, B.A.1    Bautista, N.D.2    Tanquilut, N.C.3    Anunciado, R.V.4    Leung, A.B.5    Sanchez, G.C.6    Magtoto, R.L.7    Castronuevo, P.8    Tsukamura, H.9    Maeda, K.I.10
  • 117
    • 1242329231 scopus 로고    scopus 로고
    • Antihyperglycemic effect of andrographolide in streptozotocin induced diabetic rats
    • 10.1055/s-2003-45185, 14750020
    • Yu BC, Hung CR, Chen WC, Cheng JT. Antihyperglycemic effect of andrographolide in streptozotocin induced diabetic rats. Planta Med 2003, 69:1075-1079. 10.1055/s-2003-45185, 14750020.
    • (2003) Planta Med , vol.69 , pp. 1075-1079
    • Yu, B.C.1    Hung, C.R.2    Chen, W.C.3    Cheng, J.T.4
  • 118
    • 45849092979 scopus 로고    scopus 로고
    • Mediation of β-endorphin in andrographolide induced plasma glucose lowering action in type I diabetes like animals
    • Yu BC, Chang CK, Su CF, Cheng JT. Mediation of β-endorphin in andrographolide induced plasma glucose lowering action in type I diabetes like animals. Naunyn-Schmiedeberg's Arch Pharmacol 2008, 377:529-540.
    • (2008) Naunyn-Schmiedeberg's Arch Pharmacol , vol.377 , pp. 529-540
    • Yu, B.C.1    Chang, C.K.2    Su, C.F.3    Cheng, J.T.4
  • 119
    • 68349146183 scopus 로고    scopus 로고
    • Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment
    • Zhang Z, Jiang J, Yu P, Zeng X, Larrick JW, Wang Y. Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment. J Translational Med 2009, 7:62-73.
    • (2009) J Translational Med , vol.7 , pp. 62-73
    • Zhang, Z.1    Jiang, J.2    Yu, P.3    Zeng, X.4    Larrick, J.W.5    Wang, Y.6
  • 120
    • 0037205641 scopus 로고    scopus 로고
    • Mechanism of the superoxide scavenging activity of Neoandrographolide a natural product from Andrographis paniculata Nees
    • 10.1021/jf025556f, 12137494
    • Kamdem RE, Sang S, Ho CT. Mechanism of the superoxide scavenging activity of Neoandrographolide a natural product from Andrographis paniculata Nees. J Agric Food Chem 2002, 50:4662-4665. 10.1021/jf025556f, 12137494.
    • (2002) J Agric Food Chem , vol.50 , pp. 4662-4665
    • Kamdem, R.E.1    Sang, S.2    Ho, C.T.3
  • 121
    • 0034882865 scopus 로고    scopus 로고
    • Modulatory influence of Andrographis paniculata on mouse hepatic and extrahepatic carcinogen metabolizing enzymes and antioxidant status
    • 10.1002/ptr.730, 11507728
    • Singh RP, Banerjee S, Rao AR. Modulatory influence of Andrographis paniculata on mouse hepatic and extrahepatic carcinogen metabolizing enzymes and antioxidant status. Phytother Res 2001, 15:382-390. 10.1002/ptr.730, 11507728.
    • (2001) Phytother Res , vol.15 , pp. 382-390
    • Singh, R.P.1    Banerjee, S.2    Rao, A.R.3
  • 122
    • 55949131497 scopus 로고    scopus 로고
    • Analysis of urinary andrographolides and antioxidants after oral administration of Andrographis paniculata leaf extract in rats
    • 10.1016/j.fct.2008.09.008, 18824206
    • Akowuah GA, Zhari I, Mariam A. Analysis of urinary andrographolides and antioxidants after oral administration of Andrographis paniculata leaf extract in rats. Food Chem Toxicol 2008, 46:3616-3620. 10.1016/j.fct.2008.09.008, 18824206.
    • (2008) Food Chem Toxicol , vol.46 , pp. 3616-3620
    • Akowuah, G.A.1    Zhari, I.2    Mariam, A.3
  • 123
    • 57349155315 scopus 로고    scopus 로고
    • Antioxidant action of Andrographis paniculata on lymphoma
    • 10.1007/s11033-007-9119-x, 17805989
    • Verma N, Vinayak M. Antioxidant action of Andrographis paniculata on lymphoma. Mol Biol Rep 2008, 35:535-540. 10.1007/s11033-007-9119-x, 17805989.
    • (2008) Mol Biol Rep , vol.35 , pp. 535-540
    • Verma, N.1    Vinayak, M.2
  • 124
    • 67650133615 scopus 로고    scopus 로고
    • Antioxidant, antioedema and analgesic activities of Andrographis paniculata extracts and their active constituent andrographolide
    • 10.1002/ptr.2701, 19142986
    • Lin FL, Wu SJ, Lee SC, Ng LT. Antioxidant, antioedema and analgesic activities of Andrographis paniculata extracts and their active constituent andrographolide. Phytother Res 2009, 23:958-964. 10.1002/ptr.2701, 19142986.
    • (2009) Phytother Res , vol.23 , pp. 958-964
    • Lin, F.L.1    Wu, S.J.2    Lee, S.C.3    Ng, L.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.