Determination and variation of three active diterpenoids in Andrographis paniculata (Burm.f.) Nees

Phytochemical Analysis

Volumn 15, Issue 6, 2004, Pages 365-371

  Pholphana, Nanthanit ^a   Rangkadilok, Nuchanart ^a   Thongnest, Sanit ^b   Ruchirawat, Somsak ^b   Ruchirawat, Mathuros ^c,d   Satayavivad, Jutamaad ^a,d  

^a Chulabhorn Research Institute   (Thailand)

^b Toxicology and Management of Chemicals   (Thailand)

^c Toxicology and Management of Chemicals   (Thailand)

^d MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Andrographis paniculata; Diterpenoids; HPLC; Stability; Variation

Indexed keywords

FOOD STORAGE; LIPIDS;

ACTIVE COMPOUNDS; ANDROGRAPHIS PANICULATA; ANDROGRAPHOLIDE; DITERPENOIDS; HPLC; METHANOL EXTRACT; RAPID METHOD; SIMPLE METHOD; SIMULTANEOUS DETERMINATIONS; VARIATION;

METHANOL;

14 DEOXY 11, 12 DIDEHYDROANDROGRAPHOLIDE; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; DITERPENOID; NEOANDROGRAPHOLIDE; UNCLASSIFIED DRUG;

ANDROGRAPHIS PANICULATA; ARTICLE; CHEMICAL STRUCTURE; DRUG DETERMINATION; DRUG EFFICACY; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLANT LEAF; PLANT STEM; ROOM TEMPERATURE; THAILAND;

ANDROGRAPHIS PANICULATA;

EID: 9944239247     PISSN: 09580344     EISSN: None     Source Type: Journal    
DOI: 10.1002/pca.789     Document Type: Article

References (31)

1. Caceres DD, Hancke JL, Burgos RA, Sandberg F, Wikman GK. 1999. Use of visual analogue scale measurements (VAS) to assess the effectiveness of standardized Andrographis paniculata extract SHA-10 in reducing the symptoms of common cold. A randomized double blind-placebo study. Phytomedicine 6: 217-223.
2. Calabrese C, Berman SH, Babish JG, Ma X, Shinto L, Dorr M, Wells K, Wenner CA, Standish LJ. 2000. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 14 333-338.
3. Chauhan SK, Singh BP, Kimothi GP, Agrawal S. 1999. Determination of andrographolide in Andrographis paniculata by high performance thin layer chromatography. Indian Drugs 36: 130-132.
4. Cheung HY, Cheung CS, Kong CK. 2001. Determination of bioactive diterpenoids from Andrographis paniculata by micellar electrokinetic chromatography. J Chromatogr A 930: 171-176.
5. Clander R, Srivastava V, Tandon J, Kapoor NK. 1995. Antihepatotoxic activity of diterpenes of Andrographis paniculata (Kal-Megh) against Plasmodium berghei induced hepatic damage in Mastomys natalensis. Int J Pharmacog 33: 135-138.
6. Dechatiwonse Na Ayudhya T, Techadamrongsin Y, Jirawattanapong W. 1993. Chemical Specification of Thai Herbal Drugs, Vol. 1. Department of Medicinal Sciences, Ministry of Public Health: Bangkok.
7. Du Q, Jerz G, Winterhalter P. 2003. Separation of andrographolide and neoandrographolide from the leaves of Andrographis paniculata using high-speed counter-current chromatography. J Chromatogr A 984: 147-151.
8. Gupta S, Yadava JNS, Tandon JS. 1993. Antisecretory (antidiarrhoeal) activity of Indian medicinal plants against Escherichia coli enterotoxin-incluced secretion in rabbit and guinea pig ileal loop model. Int J Pharmacog 31: 198-204.
9. Handa SS, Sharma A. 1990. Hepatoprotective activity of andrographolide against galactosamine and paracetamol intoxication in rats. Indian J Med Res (B) 92: 284-292.
10. Jain DC, Gupta MM, Saxean S, Kumar S. 2000. LC analysis of hepatoprotective diterpenoids from Andrographis paniculata. J Pharm Biomed Anal 22: 705-709.
11. Jewvachdamrongkul Y, Jirawattanapong W, Dechatiwongse T. 1990. Modified method for determination of total lactones in Andrographis herb. Bull Dept Med Sci 32: 53-61.
12. Kapil A, Koul IB, Banerjee SK, Gupta BD. 1993. Antihepatotoxic effects of major diterpenoids constituents of Andrographis paniculata. Biochem Pharmac 46: 182-185.
13. Laorpaksa A, Amnuoypol S, Jongbunprasert V. 1988. Preliminary study on antibacterial action of Thai medicinal plants for respiration tract infection (I). Thai J Pharm Sci 13: 23-36.
14. Li W, Fitzloff JF. 2002. Determination of andrographolide in commercial andrographis (Andrographis paniculata) products using HPLC with evaporative light scattering detection. J Liq Chromatogr Relat Technol 25: 1335-1343.
15. Lomlim L, Jirayupong N, Plubrukarn A. 2003. Heat-accelerated degradation of solid-state andrographolide. Chem Pharm Bull 51 24-26.
16. Matsuda T, Kuroyanagi M, Sugiyama S, Umehara K, Ueno A, Nishi K. 1994. Cell differentiation-induced diterpenes from Andrographis paniculata. Chem Pharm Bull 42: 1216-1225.
17. Ministry of Public Health. 1995. Fa Tha Lai. In Thai Herbal Pharmacopoeia, Vol. 1. Department of Medicinal Science, Prachachon Co. Ltd: Thailand; 24-31.
18. Misra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. 1992. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natatensis. Int J Pharmacog 30: 263-274.
19. Najila MJS, Rain AN, Kamel AGM, Zahir SIS, Khozirah S, Hakim SL, Zakiah I, Azizol AK. 2002. The screening of extracts from Goniothalamus scortechinii, Aralidium pinnatifidum and Andrographis paniculata for antimalarial activity using the lactate dehydrogenase assay. J Ethnopharmac 82: 239-242.
20. Otake T, Mori H, Morimoto M, Ueba N, Sutardjo S, Kusumoto IT, Hattori M, Namba T. 1995. Screening of Indonesian plant extracts for anti-human immuno-defficiency virus-type 1 (HIV-1) activity. Phytother Res 9: 6-10.
21. Puri A, Axena R, Saxena RP, Saxena KC, Srivastava V, Tandon JS. 1993. Immunostimulant agents from Andrographis paniculata. J Nat Prod 56: 995-999.
22. Rajani M, Shrivastava N, Ravishankara MN. 2000. A rapid method for isolation of andrographolide from Andrographis paniculata Nees (Kalmegh). Pharm Biol 38: 204-209.
23. Sahasitiwat S. 2002. The study of acute cardiovascular toxicity of diterpenoid lactones isolated from Andrographis panuculata (Burm.f.) Nees. Masters thesis, Mahidol University, Bangkok, Thailand.
24. Saxena S, Jain DC, Gupta MM, Sharma RP. 2000. High performance thin layer chromatographic separation of hepatoprotective diterpenoids from Andrographis paniculata. Phytochem Anal 11: 34-36.
25. Shen YC, Chen CF, Chiou WF. 2000. Suppression of rat neutrophil reactive oxygen species production and adhesion by the diterpenoid lactone andrographolide. Planta Med 66: 314-317.
26. Thanagkul B, Chaichantipayut C. 1985. Double-blind study of Andrographis paniculata Nees and tetracycline in acute diarrhea and bacillary dysentery. Ramathibodi Med J 8: 57-61.
27. Tipakorn N. 2002. Effects of Andrographis paniculata (Burm.F.) Nees on performance, mortality and coccidiosis in broiler chickens. PhD thesis, Institute of Animal Physiology and Animal Nutrition, Georg-August-Universität, Göttingen.
28. Vedavathy S, Rao KN. 1991. Antipyretic activity of six indigenous medicinal plants of Tirumala Hills, Andhra Pradesh, India. J Ethnopharmac 33: 193-196.
29. Zhang CY, Tan BKH. 1997. Mechanism of cardiovascular activity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmac 56: 97-101.
30. Zhang CY, Kuroyangi M, Tan BKH. 1998. Cardiovascular activity of 14-deoxy 11, 12-didehydroandrographolide in the anaesthetized rat and isolated right atria. Pharmac Res 38: 413-417.
31. Zhao J, Yang G, Liu H, Wang D, Song X, Chen Y. 2002. Determination of andrographolide, deoxyandrographolide and neoandrographolide in the Chinese herb Andrographis paniculata by micellar electrokinetic capillary chromatography. Phytochem Anal 13: 222-227.