Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E2 production in LPS-stimulated murine macrophage

Molecular and Cellular Biochemistry

Volumn 298, Issue 1-2, 2007, Pages 49-57

  Liu, Jun ^a,b   Wang, Zheng Tao ^a   Ji, Li Li ^a   Ge, Bao Xue ^c  

^a SHANGHAI UNIVERSITY   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

COX 2; iNOS; Macrophage; Neoandrographolide; NO; P38 MAPKs; PGE2

Indexed keywords

ANDROGRAPHIS PANICULATA EXTRACT; ANTIINFLAMMATORY AGENT; BACTERIUM LIPOPOLYSACCHARIDE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEOANDROGRAPHOLIDE; NITRIC OXIDE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; IMMUNOBLOTTING; INHIBITION KINETICS; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ANIMALS; CYCLOOXYGENASE 2; DINOPROSTONE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSIDES; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; TETRAHYDRONAPHTHALENES;

ANDROGRAPHIS PANICULATA; BACTERIA (MICROORGANISMS); MURINAE;

EID: 34247281583     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9349-6     Document Type: Article

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