Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration

European Journal of Pharmacology

Volumn 498, Issue 1-3, 2004, Pages 45-52

  Tsai, Hwei Ru ^a   Yang, Li Ming ^b   Tsai, Wei Jern ^b   Chiou, Wen Fei ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b Natl Res Inst of Chinese Medicine   (Taiwan)

Author keywords

Akt; Andrographolide; Chemotactic migration; ERK1 2; MAPK

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANDROGRAPHOLIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COMPLEMENT COMPONENT C5A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; WORTMANNIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IC 50; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 4444376879     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.07.077     Document Type: Article

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