Andrographolide Reduces Inflammation-Mediated Dopaminergic Neurodegeneration in Mesencephalic Neuron-Glia Cultures by Inhibiting Microglial Activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 3, 2004, Pages 975-983

  Wang, Tongguang ^a   Liu, Bin ^a,b   Zhang, Wei ^a,c   Wilson, Belinda ^a   Hong, Jau Shyong ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ANDROGRAPHOLIDE; CYCLOOXYGENASE 2; DOPAMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; TRITIUM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG EFFECT; GLIA; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MESENCEPHALON; MICROGLIA; NERVE CELL; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CELLS, CULTURED; CYCLOOXYGENASE 2; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; INFLAMMATION; ISOENZYMES; LIPOPOLYSACCHARIDES; MALE; MESENCEPHALON; MICROGLIA; NERVE DEGENERATION; NEUROGLIA; NEURONS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, INBRED F344;

EID: 1342323332     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.059683     Document Type: Article

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