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Volumn 61, Issue 1, 2010, Pages 121-146

Antineoplastic drugs as a potential risk factor in occupational settings: Mechanisms of action at the cell level, genotoxic effects, and their detection using different biomarkers;Antineoplastični Lijekovi Kao Čimbenik Rizika u Radnom Okolišu: Mehanizmi Djelovanja na Razini Stanice i Pregled Metoda za Otkrivanje Njihovih Genotoksičnih Učinaka

Author keywords

Chromosome aberrations; Comet assay; DNA; Izmjene sestrinskih kromatida; Komet test; Kromosomske aberacije; Micronuclei; Mikronukleus test; Sister chromatid exchanges

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER;

EID: 77950253491     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: 10.2478/10004-1254-61-2010-2025     Document Type: Review
Times cited : (11)

References (212)
  • 7
    • 0018785705 scopus 로고
    • Mutagenicity in urine of nurses handling cytostatic drugs
    • Falck K, Grohn P, Sorsa M. Mutagenicity in urine of nurses handling cytostatic drugs. Lancet 1979;1:1250-1251
    • (1979) Lancet , vol.1 , pp. 1250-1251
    • Falck, K.1    Grohn, P.2    Sorsa, M.3
  • 8
    • 0030591653 scopus 로고    scopus 로고
    • Mutagenic damage to mammalian cells by therapeutic alkylating agents
    • Sanderson BJ, Shield AJ. Mutagenic damage to mammalian cells by therapeutic alkylating agents. Mutat Res 1996;355:41-57.
    • (1996) Mutat Res , vol.355 , pp. 41-57
    • Sanderson, B.J.1    Shield, A.J.2
  • 9
    • 0030591670 scopus 로고    scopus 로고
    • Mutagenic and carcinogenic properties of platinum-based anticencer drugs
    • Sanderson BJ, Ferguson LR, Denny WA. Mutagenic and carcinogenic properties of platinum-based anticencer drugs. Mutat Res 1996;355:59-70.
    • (1996) Mutat Res , vol.355 , pp. 59-70
    • Sanderson, B.J.1    Ferguson, L.R.2    Denny, W.A.3
  • 10
    • 0030591660 scopus 로고    scopus 로고
    • Genetic activity profiles of anticancer drugs
    • Jacobson MA, Stack HF, Waters MD. Genetic activity profiles of anticancer drugs. Mutat Res 1996;355:171-208.
    • (1996) Mutat Res , vol.355 , pp. 171-208
    • Jacobson, M.A.1    Stack, H.F.2    Waters, M.D.3
  • 11
    • 0020661601 scopus 로고
    • Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and sister chromatid exchanges in chinese hamster ovary cells
    • Singh B, Gupta RS. Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and sister chromatid exchanges in chinese hamster ovary cells. Cancer Res 1983;43:577-584
    • (1983) Cancer Res , vol.43 , pp. 577-584
    • Singh, B.1    Gupta, R.S.2
  • 16
    • 2142823779 scopus 로고    scopus 로고
    • Activation of the anticancer prodrugs cyclophosphamide and ifosfamide: Identification of cytochrome P450 2B enzymes and site-specific mutants with improved enzyme kinetics
    • Chen C-S, Lin JT, Goss KA, He Y, Halpert JR, Waxman DJ. Activation of the anticancer prodrugs cyclophosphamide and ifosfamide: identification of cytochrome P450 2B enzymes and site-specific mutants with improved enzyme kinetics. Mol Pharmacol 2004;65:1278-1285
    • (2004) Mol Pharmacol , vol.65 , pp. 1278-1285
    • Chen, C.-S.1    Lin, J.T.2    Goss, K.A.3    He, Y.4    Halpert, J.R.5    Waxman, D.J.6
  • 18
    • 0005578015 scopus 로고    scopus 로고
    • urednik. 7. izd. Philadelphia: Lippincot Williams and Wilkins
    • Skeel RT, urednik. Handbook of Cancer Chemotherapy. 7. izd. Philadelphia: Lippincot Williams and Wilkins; 2007.
    • (2007) Handbook of Cancer Chemotherapy
    • Skeel, R.T.1
  • 19
    • 0035950830 scopus 로고    scopus 로고
    • Separation methods for alkylating antineoplastic compounds
    • Paci A, Rieutord A, Brion F, Prognon P. Separation methods for alkylating antineoplastic compounds. J Chrom B 2001;764:255-287
    • (2001) J Chrom B , vol.764 , pp. 255-287
    • Paci, A.1    Rieutord, A.2    Brion, F.3    Prognon, P.4
  • 20
  • 21
    • 4444343745 scopus 로고    scopus 로고
    • American Cancer Society. Malden (MA): Blackwell Science Inc. urednici. 2. izd
    • American Cancer Society, Lenhard RE, Osteen RT, Gansler TS, urednici. Clinical Oncology. 2. izd. Malden (MA): Blackwell Science Inc.; 2001.
    • (2001) Clinical Oncology
    • Lenhard, R.E.1    Osteen, R.T.2    Gansler, T.S.3
  • 24
    • 0017336729 scopus 로고
    • Genetic toxicology of mitomycin C, actinomycins, daunomycin and adriamycin
    • Vig BK. Genetic toxicology of mitomycin C, actinomycins, daunomycin and adriamycin. Mutat Res 1977;48:189-238.
    • (1977) Mutat Res , vol.48 , pp. 189-238
    • Vig, B.K.1
  • 25
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999;57:727-741
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 26
    • 0018236017 scopus 로고
    • Genetic toxicology of bleomycin
    • Vig BK, Lewis R. Genetic toxicology of bleomycin. Mutat Res 1978;55:121-145
    • (1978) Mutat Res , vol.55 , pp. 121-145
    • Vig, B.K.1    Lewis, R.2
  • 27
    • 0000576972 scopus 로고
    • Genotoxicity of bleomycin
    • Povirk LF, Austin MJF. Genotoxicity of bleomycin. Mutat Res 1991;257:127-143
    • (1991) Mutat Res , vol.257 , pp. 127-143
    • Povirk, L.F.1    Austin, M.J.F.2
  • 28
    • 0028951982 scopus 로고
    • Bleomycin sulfate-induced micronuclei in human, rat, and mouse peripheral blood lymphocytes
    • Erexson GL, Bryant MF, Kwanyuen P, Kligerman AD. Bleomycin sulfate-induced micronuclei in human, rat, and mouse peripheral blood lymphocytes. Environ Mol Mutagen 1995;25:31-36
    • (1995) Environ Mol Mutagen , vol.25 , pp. 31-36
    • Erexson, G.L.1    Bryant, M.F.2    Kwanyuen, P.3    Kligerman, A.D.4
  • 29
    • 0028948271 scopus 로고
    • Chromosome damage induced by carboplatin (CBDCA)
    • Gonzalez-Cid M, Mudry M, Larripa I. Chromosome damage induced by carboplatin (CBDCA). Toxicol Lett 1995;76:97-103.
    • (1995) Toxicol Lett , vol.76 , pp. 97-103
    • Gonzalez-Cid, M.1    Mudry, M.2    Larripa, I.3
  • 30
    • 77950246014 scopus 로고    scopus 로고
    • British Columbia Cancer Agency (BCCA). Dostupno na
    • British Columbia Cancer Agency (BCCA). BC Cancer Agency Cancer Drug Manualc Oxaliplatin [pristup 20. siječnja 2010.]. Dostupno na http://www.bccancer.bc.ca/NR/rdonlyres/ D0132051-8601-4B5E-89A0-5BB3B4739C83/ 31059/ Oxaliplatinmonograph-1Nov08-formatted.pdf.
    • BC Cancer Agency Cancer Drug Manualc Oxaliplatin [Pristup 20. Siječnja 2010.]
  • 32
  • 33
    • 77950213096 scopus 로고    scopus 로고
    • British Columbia Cancer Agency (BCCA). Dostupno na
    • British Columbia Cancer Agency (BCCA). BC Cancer Agency Cancer Drug Manualc Amsacrine [pristup 20. siječnja 2010.]. Dostupno na http://www.bccancer. bc.ca/NR/rdonlyres/DC04BEFB-BF13-4A48-91A8- 976A9650C6B8/30156/Amsacrinemonograph-1Sept08. pdf
    • BC Cancer Agency Cancer Drug Manualc Amsacrine [Pristup 20. Siječnja 2010.]
  • 34
    • 0026778383 scopus 로고
    • Mechanism of action of hydroxyurea
    • Yarbro JW. Mechanism of action of hydroxyurea. Semin Oncol 1992;19(Suppl 9):1-10.
    • (1992) Semin Oncol , vol.19 , Issue.SUPPL. 9 , pp. 1-10
    • Yarbro, J.W.1
  • 35
    • 0026755811 scopus 로고
    • An overview of the clinical experience with hydroxyurea
    • Donehower RC. An overview of the clinical experience with hydroxyurea. Semin Oncol 1992;19(Suppl 9):11-19
    • (1992) Semin Oncol , vol.19 , Issue.SUPPL. 9 , pp. 11-19
    • Donehower, R.C.1
  • 37
    • 0031884195 scopus 로고    scopus 로고
    • Induction of aneuploidy by the antineoplastic drug estramustine in human lymphocytes
    • Migliore L, Cocchi R, Scarpato R, Sbrana I. Induction of aneuploidy by the antineoplastic drug estramustine in human lymphocytes. Mutat Res 1998;412:33-40.
    • (1998) Mutat Res , vol.412 , pp. 33-40
    • Migliore, L.1    Cocchi, R.2    Scarpato, R.3    Sbrana, I.4
  • 38
    • 33845410111 scopus 로고    scopus 로고
    • Preventing occupational exposures to antineoplastic drugs in health care settings
    • Connor TH, McDiarmid MA. Preventing occupational exposures to antineoplastic drugs in health care settings. CA Cancer J Clin 2006;56:354-365
    • (2006) CA Cancer J Clin , vol.56 , pp. 354-365
    • Connor, T.H.1    McDiarmid, M.A.2
  • 40
    • 33746612399 scopus 로고    scopus 로고
    • ASHP guidelines on handling hazardous drugs
    • American Society of Health-System Pharmacists
    • American Society of Health-System Pharmacists. ASHP guidelines on handling hazardous drugs. Am J Health-Syst Pharm 2006;63:1172-1193
    • (2006) Am J Health-Syst Pharm , vol.63 , pp. 1172-1193
  • 42
    • 0037989063 scopus 로고    scopus 로고
    • Biological and environmental monitoring of hospital personnel exposed to antineoplastic agent: A review of analytical methods
    • Turci R, Sottani C, Spagnoli G, Minoia C. Biological and environmental monitoring of hospital personnel exposed to antineoplastic agent: a review of analytical methods. J Chrom B 2003;789:169-209.
    • (2003) J Chrom B , vol.789 , pp. 169-209
    • Turci, R.1    Sottani, C.2    Spagnoli, G.3    Minoia, C.4
  • 45
    • 0019457892 scopus 로고
    • Chromosome analyses of nurses handling cytostatic agents
    • Waksvik H, Klepp O, Brogger A. Chromosome analyses of nurses handling cytostatic agents. Cancer Treat Rep 1981;65:607-610
    • (1981) Cancer Treat Rep , vol.65 , pp. 607-610
    • Waksvik, H.1    Klepp, O.2    Brogger, A.3
  • 47
    • 0020579335 scopus 로고
    • No elevation of the frequencies of chromosomal alterations as a consequence of handling cytostatic drugs: Analyses with peripheral blood and urine of hospital personnel
    • Stiller A, Obe G, Boll I, Pribilla W. No elevation of the frequencies of chromosomal alterations as a consequence of handling cytostatic drugs: Analyses with peripheral blood and urine of hospital personnel. Mutat Res 1983;121:253-259
    • (1983) Mutat Res , vol.121 , pp. 253-259
    • Stiller, A.1    Obe, G.2    Boll, I.3    Pribilla, W.4
  • 48
    • 0022262266 scopus 로고
    • Sister-chromatid exchanges in lymphocytes and mutagenicity in urine of nurses handling cytostatic drugs
    • Barale R, Sozzi G, Toniolo P, Borghi O, Reali D, Loprieno N, Della Porta G. Sister-chromatid exchanges in lymphocytes and mutagenicity in urine of nurses handling cytostatic drugs. Mutat Res 1985;157:235-240
    • (1985) Mutat Res , vol.157 , pp. 235-240
    • Barale, R.1    Sozzi, G.2    Toniolo, P.3    Borghi, O.4    Reali, D.5    Loprieno, N.6    Della Porta, G.7
  • 50
    • 0022871782 scopus 로고
    • Chromosomal aberrations, SCE and urine mutagenicity in workers occupationally exposed to cytostatic drugs
    • Pohlova H, Černa M, Rossner P. Chromosomal aberrations, SCE and urine mutagenicity in workers occupationally exposed to cytostatic drugs. Mutat Res 1986;174:213-217
    • (1986) Mutat Res , vol.174 , pp. 213-217
    • Pohlova, H.1    Černa, M.2    Rossner, P.3
  • 51
    • 0022642022 scopus 로고
    • Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs
    • Stucker I, Hirsch A, Doloy T, Bastie-Sigeac I, Hemon D. Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs. Int Arch Occup Environ Health 1986;57:195-205.
    • (1986) Int Arch Occup Environ Health , vol.57 , pp. 195-205
    • Stucker, I.1    Hirsch, A.2    Doloy, T.3    Bastie-Sigeac, I.4    Hemon, D.5
  • 52
    • 0023901387 scopus 로고
    • Sister-chromatid exchanges and chromosomal aberrations in lymphocytes of nurses handling cytostatic agents
    • Benhamou S, Pot-Deprun J, Sancho-Garnier H, Chouroulinkov I. Sister-chromatid exchanges and chromosomal aberrations in lymphocytes of nurses handling cytostatic agents. Int J Cancer 1988;41:350-353
    • (1988) Int J Cancer , vol.41 , pp. 350-353
    • Benhamou, S.1    Pot-Deprun, J.2    Sancho-Garnier, H.3    Chouroulinkov, I.4
  • 53
    • 0023911368 scopus 로고
    • Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitals
    • Sorsa M, Pyy L, Salomaa S, Nyland L, Yager JW. Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitals. Mutat Res 1988;204:465-479
    • (1988) Mutat Res , vol.204 , pp. 465-479
    • Sorsa, M.1    Pyy, L.2    Salomaa, S.3    Nyland, L.4    Yager, J.W.5
  • 55
    • 0025089564 scopus 로고
    • Chromosome and SCE analysis in peripheral lymphocytes of persons occupationally exposed to cytostatic drugs handled with and without use of safety covers
    • Oestreicher U, Stephan G, Glatzel M. Chromosome and SCE analysis in peripheral lymphocytes of persons occupationally exposed to cytostatic drugs handled with and without use of safety covers. Mutat Res 1990;242:271-277
    • (1990) Mutat Res , vol.242 , pp. 271-277
    • Oestreicher, U.1    Stephan, G.2    Glatzel, M.3
  • 56
    • 0025605177 scopus 로고
    • Chromosomal aberrations, sister chromatid exchanges and urinary thioethers in nurses handling antineoplastic drugs
    • Sarto F, Trevisan A, Tomanin R, Canova A, Fiorentino M. Chromosomal aberrations, sister chromatid exchanges and urinary thioethers in nurses handling antineoplastic drugs. Am J Ind Med 1990;18:689-695
    • (1990) Am J Ind Med , vol.18 , pp. 689-695
    • Sarto, F.1    Trevisan, A.2    Tomanin, R.3    Canova, A.4    Fiorentino, M.5
  • 57
    • 0025755964 scopus 로고
    • Evaluation of genotoxic risk of handling cytostatic drugs in clinical pharmacy practice
    • Guinee EP, Beuman GH, Hageman G, Welle IJ, Kleinjans JC. Evaluation of genotoxic risk of handling cytostatic drugs in clinical pharmacy practice. Pharm Weekblad 1991;13:78-82.
    • (1991) Pharm Weekblad , vol.13 , pp. 78-82
    • Guinee, E.P.1    Beuman, G.H.2    Hageman, G.3    Welle, I.J.4    Kleinjans, J.C.5
  • 58
    • 0025876804 scopus 로고
    • Chromosomal abnormalities among nurses occupationally exposed to antineoplastic drugs
    • Milkovǐ-Kraus S, Horvat D. Chromosomal abnormalities among nurses occupationally exposed to antineoplastic drugs. Am J Ind Med 1991;19:771-774
    • (1991) Am J Ind Med , vol.19 , pp. 771-774
    • Milkovič-Kraus, S.1    Horvat, D.2
  • 60
    • 0026088963 scopus 로고
    • Sister chromatid exchanges in lymphocytes of nurses handling antineoplastic drugs
    • Šardaš S, Gok, S, Karakaya AE. Sister chromatid exchanges in lymphocytes of nurses handling antineoplastic drugs. Toxicol Lett 1991;55:311-315
    • (1991) Toxicol Lett , vol.55 , pp. 311-315
    • Šardaš, S.1    Gok, S.2    Karakaya, A.E.3
  • 61
    • 0026565666 scopus 로고
    • Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs
    • Goloni-Bertollo EM, Tajara EH, Manzato AJ, Varella-Garcia M. Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs. Int J Cancer 1992;50:341-344
    • (1992) Int J Cancer , vol.50 , pp. 341-344
    • Goloni-Bertollo, E.M.1    Tajara, E.H.2    Manzato, A.J.3    Varella-Garcia, M.4
  • 62
    • 0026734303 scopus 로고
    • Baseline and phosphoramide mustardinduced sister-chromatid exchanges in pharmacists handling anti-cancer drugs
    • McDiarmid MA, Kolodner K, Humphrey F, Putman D, Jacobson-Kram D. Baseline and phosphoramide mustardinduced sister-chromatid exchanges in pharmacists handling anti-cancer drugs. Mutat Res 1992;279:199-204.
    • (1992) Mutat Res , vol.279 , pp. 199-204
    • McDiarmid, M.A.1    Kolodner, K.2    Humphrey, F.3    Putman, D.4    Jacobson-Kram, D.5
  • 63
    • 0027438484 scopus 로고
    • The influence of cigarette smoking on sister chromatid exchange frequencies in peripheral lymphocytes among nurses handling cytostatic drugs
    • Gorecka D, Gorski T. The influence of cigarette smoking on sister chromatid exchange frequencies in peripheral lymphocytes among nurses handling cytostatic drugs. Pol J Occup Med Environ Health 1993;6:143-148
    • (1993) Pol J Occup Med Environ Health , vol.6 , pp. 143-148
    • Gorecka, D.1    Gorski, T.2
  • 64
    • 0028170844 scopus 로고
    • Analysis of chromosomal aberrations, sister chromatid exchanges and micronuclei in peripheral lymphocytes of pharmacists before and after working with cytostatic drugs
    • Roth S, Norppa H, Jarventaus H, Kyyronen P, Ahonen M, Lehtomaki J, Sainio H, Sorsa M. Analysis of chromosomal aberrations, sister chromatid exchanges and micronuclei in peripheral lymphocytes of pharmacists before and after working with cytostatic drugs. Mutat Res 1994;325:157-162
    • (1994) Mutat Res , vol.325 , pp. 157-162
    • Roth, S.1    Norppa, H.2    Jarventaus, H.3    Kyyronen, P.4    Ahonen, M.5    Lehtomaki, J.6    Sainio, H.7    Sorsa, M.8
  • 65
    • 77950255316 scopus 로고
    • Cytogenetic monitoring of pharmaceutical staff working with cytostatic drug preparations: A 5-year follow-up
    • Peschke M, Nagel S, Haamann F, Melzer S, Meier K. Cytogenetic monitoring of pharmaceutical staff working with cytostatic drug preparations: A 5-year follow-up. J Oncol Pharm Pract 1995;1:33-39
    • (1995) J Oncol Pharm Pract , vol.1 , pp. 33-39
    • Peschke, M.1    Nagel, S.2    Haamann, F.3    Melzer, S.4    Meier, K.5
  • 66
    • 0028826438 scopus 로고
    • Occupational exposure to nor-nitrogen mustard: Chemical and biological monitoring
    • Thulin H, Sundberg E, Hansson K, Cole J, Hartley-Asp B. Occupational exposure to nor-nitrogen mustard: Chemical and biological monitoring. Toxicol Ind Health 1995;11:89-97.
    • (1995) Toxicol Ind Health , vol.11 , pp. 89-97
    • Thulin, H.1    Sundberg, E.2    Hansson, K.3    Cole, J.4    Hartley-Asp, B.5
  • 67
    • 0029757741 scopus 로고    scopus 로고
    • Work environment influence on cytostatics-induced genotoxicity in oncologic nurses
    • Brumen V, Horvat D. Work environment influence on cytostatics-induced genotoxicity in oncologic nurses. Am J Ind Med 1996;30:67-71.
    • (1996) Am J Ind Med , vol.30 , pp. 67-71
    • Brumen, V.1    Horvat, D.2
  • 68
    • 0030760675 scopus 로고    scopus 로고
    • Biological monitoring of hospital pharmacy personnel occupationally exposed to cytostatic drugs: Urinary excretion and cytogenetic studies
    • Ensslin AS, Huber R, Pethran A, Rommelt H, Schierl R, Kulka U, Fruhmann G. Biological monitoring of hospital pharmacy personnel occupationally exposed to cytostatic drugs: urinary excretion and cytogenetic studies. Int Arch Occup Environ Health 1997;70:205-208
    • (1997) Int Arch Occup Environ Health , vol.70 , pp. 205-208
    • Ensslin, A.S.1    Huber, R.2    Pethran, A.3    Rommelt, H.4    Schierl, R.5    Kulka, U.6    Fruhmann, G.7
  • 69
    • 0031715559 scopus 로고    scopus 로고
    • Cytogenetic consequences after occupational exposure to antineoplastic drugs
    • Fučić A, Jazbec A, Mijić A, Šešo- Šimić D, Tomek R. Cytogenetic consequences after occupational exposure to antineoplastic drugs. Mutat Res 1998;416:59-66.
    • (1998) Mutat Res , vol.416 , pp. 59-66
    • Fučić, A.1    Jazbec, A.2    Mijić, A.3    Šešo- Šimić, D.4    Tomek, R.5
  • 70
    • 0031947806 scopus 로고    scopus 로고
    • Human effect monitoring in cases of occupational exposure to antineoplastic drugs: A method comparison
    • Kevekordes S, Gebel TW, Hellwig M, Dames W, Dunkelberg H. Human effect monitoring in cases of occupational exposure to antineoplastic drugs: A method comparison. Occup Environ Med 1998;55:145-149
    • (1998) Occup Environ Med , vol.55 , pp. 145-149
    • Kevekordes, S.1    Gebel, T.W.2    Hellwig, M.3    Dames, W.4    Dunkelberg, H.5
  • 71
    • 33847296683 scopus 로고    scopus 로고
    • Sister chromatid exchanges and chromosome aberrations in lymphocytes of medical personnel handling cytostatic drugs
    • Mahrous HS, Ismail SR, Hashishe MM, Kohail HM. Sister chromatid exchanges and chromosome aberrations in lymphocytes of medical personnel handling cytostatic drugs. J Egypt Public Health Assoc 1998;73:297-323.
    • (1998) J Egypt Public Health Assoc , vol.73 , pp. 297-323
    • Mahrous, H.S.1    Ismail, S.R.2    Hashishe, M.M.3    Kohail, H.M.4
  • 72
    • 0345044926 scopus 로고    scopus 로고
    • Analysis of sister chromatid exchange and micronuclei in peripheral blood lymphocytes of murses handling cytostatic drugs
    • Kašuba V, Rozgaj R, Garaj-Vrhovac V. Analysis of sister chromatid exchange and micronuclei in peripheral blood lymphocytes of murses handling cytostatic drugs. J Appl Toxicol 1999;19:401-404
    • (1999) J Appl Toxicol , vol.19 , pp. 401-404
    • Kašuba, V.1    Rozgaj, R.2    Garaj-Vrhovac, V.3
  • 73
    • 0345425029 scopus 로고    scopus 로고
    • Somatic mutations at the T-cell antigen receptor in antineoplastic drug-exposed populations: Comparison with sister chromatid exchange frequency
    • Lanza A, Robustelli della Cuna FS, Zibera C, Pedrazzoli P, Robustelli della Cuna G. Somatic mutations at the T-cell antigen receptor in antineoplastic drug-exposed populations: comparison with sister chromatid exchange frequency. Int Arch Environ Health 1999;72:315-322
    • (1999) Int Arch Environ Health , vol.72 , pp. 315-322
    • Lanza, A.1    Robustelli Della Cuna, F.S.2    Zibera, C.3    Pedrazzoli, P.4    Robustelli Della Cuna, G.5
  • 75
    • 0035831376 scopus 로고    scopus 로고
    • Follow-up genotoxicological monitoring of nurses handling antineoplastic drugs
    • Jakab MG, Major J, Tompa A. Follow-up genotoxicological monitoring of nurses handling antineoplastic drugs. J Tox Environ Health 2001;62:307-318
    • (2001) J Tox Environ Health , vol.62 , pp. 307-318
    • Jakab, M.G.1    Major, J.2    Tompa, A.3
  • 77
    • 34247353321 scopus 로고    scopus 로고
    • Efforts to ensure safety of hospital pharmacy personnel occupationally exposed to antineoplastic drugs during a preparation task
    • Ikeda K, Yagi Y, Tkegami M, Lu Y, Morimoto K, Kurokawa N. Efforts to ensure safety of hospital pharmacy personnel occupationally exposed to antineoplastic drugs during a preparation task. Hosp Pharm 2007;42:209-218
    • (2007) Hosp Pharm , vol.42 , pp. 209-218
    • Ikeda, K.1    Yagi, Y.2    Tkegami, M.3    Lu, Y.4    Morimoto, K.5    Kurokawa, N.6
  • 79
    • 67349260754 scopus 로고    scopus 로고
    • Assessment of genotoxic risks in Croatian health care workers occupationally exposed to cytotoxic drugs: A multi-biomarker approach
    • Kopjar N, Garaj-Vrhovac V, Kašuba V, Rozgaj R, Ramić S, Pavlica V, Želježić D. Assessment of genotoxic risks in Croatian health care workers occupationally exposed to cytotoxic drugs: A multi-biomarker approach. Int J Hyg Environ Health 2009;212:414-431
    • (2009) Int J Hyg Environ Health , vol.212 , pp. 414-431
    • Kopjar, N.1    Garaj-Vrhovac, V.2    Kašuba, V.3    Rozgaj, R.4    Ramić, S.5    Pavlica, V.6    Želježić, D.7
  • 81
    • 0023755617 scopus 로고
    • Effect of ascorbic acid prophylaxis on the frequency of chromosome aberrations, urine mutagenicity and nucleolus test in workers occupationally exposed to cytostatic drugs
    • Rossner P, Černa M, Pokorana D, Hajek V, Petr J. Effect of ascorbic acid prophylaxis on the frequency of chromosome aberrations, urine mutagenicity and nucleolus test in workers occupationally exposed to cytostatic drugs. Mutat Res 1988;208:149-153
    • (1988) Mutat Res , vol.208 , pp. 149-153
    • Rossner, P.1    Černa, M.2    Pokorana, D.3    Hajek, V.4    Petr, J.5
  • 82
    • 0025579987 scopus 로고
    • Cytogenetic analysis of peripheral lymphocytes in occupationally exposed health personnel
    • Medkova J. Cytogenetic analysis of peripheral lymphocytes in occupationally exposed health personnel. Acta Univ Palack Olomuc Facult Med 1990;126:93-106.
    • (1990) Acta Univ Palack Olomuc Facult Med , vol.126 , pp. 93-106
    • Medkova, J.1
  • 83
    • 0025865384 scopus 로고
    • Use of cytogenetic methods to determine mutagenic changes in the blood of pharmacy personnel and nurses who handle cytotoxic agents
    • Cooke J, Williams J, Morgan RJ, Cooke P, Calvert RT. Use of cytogenetic methods to determine mutagenic changes in the blood of pharmacy personnel and nurses who handle cytotoxic agents. Am J Hosp Pharm 1991;48:1199-1205
    • (1991) Am J Hosp Pharm , vol.48 , pp. 1199-1205
    • Cooke, J.1    Williams, J.2    Morgan, R.J.3    Cooke, P.4    Calvert, R.T.5
  • 84
    • 0026702749 scopus 로고
    • Environmental effects on chromosomes in oncology and radiology department personnel
    • Milković-Kraus S, Kraus O, Kršnjavi H, Kubelka D. Environmental effects on chromosomes in oncology and radiology department personnel. Prev Med 1992;21:498-502.
    • (1992) Prev Med , vol.21 , pp. 498-502
    • Milković-Kraus, S.1    Kraus, O.2    Kršnjavi, H.3    Kubelka, D.4
  • 85
    • 0027408608 scopus 로고
    • Chromosomal aberrations in peripheral lymphocytes of nurses and physicians handling antineoplastic drugs
    • Grummt T, Grummt H-J, Schott G. Chromosomal aberrations in peripheral lymphocytes of nurses and physicians handling antineoplastic drugs. Mutat Res 1993;302:19-24.
    • (1993) Mutat Res , vol.302 , pp. 19-24
    • Grummt, T.1    Grummt, H.-J.2    Schott, G.3
  • 86
    • 0028178042 scopus 로고
    • Chromosomal aberrations and micronucleus frequency in nurses occupationally exposed to cytotoxic drugs
    • Anwar WA, Salama SI, Serafy MM, Hermida S, Hafez AS. Chromosomal aberrations and micronucleus frequency in nurses occupationally exposed to cytotoxic drugs. Mutagenesis 1994;9:315-317
    • (1994) Mutagenesis , vol.9 , pp. 315-317
    • Anwar, W.A.1    Salama, S.I.2    Serafy, M.M.3    Hermida, S.4    Hafez, A.S.5
  • 87
    • 0028111709 scopus 로고
    • Urinary cyclophosphamide excretion and chromosomal aberrations in peripheral blood lymphocytes after occupational exposure to antineoplastic agents
    • Sessink PJM, Cerna M, Rossner P, Pastorkova A, Bavarova H, Frankova K, Anzion RB, Bos RP. Urinary cyclophosphamide excretion and chromosomal aberrations in peripheral blood lymphocytes after occupational exposure to antineoplastic agents. Mutat Res 1994;309:193-199
    • (1994) Mutat Res , vol.309 , pp. 193-199
    • Sessink, P.J.M.1    Cerna, M.2    Rossner, P.3    Pastorkova, A.4    Bavarova, H.5    Frankova, K.6    Anzion, R.B.7    Bos, R.P.8
  • 88
    • 0032512910 scopus 로고    scopus 로고
    • Cytogenetic analysis of peripheral lymphocytes in medical personnel by means of FISH
    • Rubeš J, Kucharova S, Vozdova M, Musilova P, Zudova Z. Cytogenetic analysis of peripheral lymphocytes in medical personnel by means of FISH. Mutat Res 1998;412:293-298
    • (1998) Mutat Res , vol.412 , pp. 293-298
    • Rubeš, J.1    Kucharova, S.2    Vozdova, M.3    Musilova, P.4    Zudova, Z.5
  • 89
    • 77950214801 scopus 로고    scopus 로고
    • Sister chromatid exchanges and micronuclei in lymphocyte of nurses handling antineoplastic drug
    • Ansari-Lari M, Saadat M, Shahryari M, Farhud DD. Sister Chromatid Exchanges and Micronuclei in Lymphocyte of Nurses Handling Antineoplastic Drug. Iranian J Publ Health 2001;30:37-40.
    • (2001) Iranian J Publ Health , vol.30 , pp. 37-40
    • Ansari-Lari, M.1    Saadat, M.2    Shahryari, M.3    Farhud, D.D.4
  • 90
    • 0036015525 scopus 로고    scopus 로고
    • Assessment of genotoxic damage in nurses occupationally exposed to antineoplastics by the analysis of chromosomal aberrations
    • Burgaz S, Karahalil B, Canhi Z, Terzioglu F, Ancel G, Anzion RB, Bos RP, Huttner E. Assessment of genotoxic damage in nurses occupationally exposed to antineoplastics by the analysis of chromosomal aberrations. Hum Exp Toxicol 2002;21:129-135
    • (2002) Hum Exp Toxicol , vol.21 , pp. 129-135
    • Burgaz, S.1    Karahalil, B.2    Canhi, Z.3    Terzioglu, F.4    Ancel, G.5    Anzion, R.B.6    Bos, R.P.7    Huttner, E.8
  • 91
    • 4544366257 scopus 로고    scopus 로고
    • An investigation on the chromosomal damage in nurses occupationally exposed to antineoplastic drugs in Chinese
    • Xu SJ. Wang JX. Yang DP. [An investigation on the chromosomal damage in nurses occupationally exposed to antineoplastic drugs, in Chinese]. Chin J Prev Med 2003;37:119-120
    • (2003) Chin J Prev Med , vol.37 , pp. 119-120
    • Xu, S.J.1    Wang, J.X.2    Yang, D.P.3
  • 93
    • 27144521453 scopus 로고    scopus 로고
    • Evaluation of genotoxic effects induced by exposure to antineoplastic drugs in lymphocytes and exfoliated buccal cells of oncology nurses and pharmacy employees
    • Cavallo D, Ursini CL, Perniconi B, Di Francesco A, Giglio M, Rubino FM, Marinaccio A, Iavicoli S. Evaluation of genotoxic effects induced by exposure to antineoplastic drugs in lymphocytes and exfoliated buccal cells of oncology nurses and pharmacy employees. Mutat Res 2005;587:45-51.
    • (2005) Mutat Res , vol.587 , pp. 45-51
    • Cavallo, D.1    Ursini, C.L.2    Perniconi, B.3    Di Francesco, A.4    Giglio, M.5    Rubino, F.M.6    Marinaccio, A.7    Iavicoli, S.8
  • 96
    • 0024224150 scopus 로고
    • Micronuclei in cytokinesisblocked lymphocytes as an index of occupational exposure to alkylating cytostatic drugs
    • Yager JW, Sorsa M, Selvin S. Micronuclei in cytokinesisblocked lymphocytes as an index of occupational exposure to alkylating cytostatic drugs. IARC Sci Publ 1988;89:213-216
    • (1988) IARC Sci Publ , vol.89 , pp. 213-216
    • Yager, J.W.1    Sorsa, M.2    Selvin, S.3
  • 98
    • 0032410723 scopus 로고    scopus 로고
    • Micronuclei in cytokinesisblocked lymphocytes as an index of occupational exposure to antineoplastic drugs
    • Garaj-Vrhovac V, Kopjar N. Micronuclei in cytokinesisblocked lymphocytes as an index of occupational exposure to antineoplastic drugs. Radiol Oncol 1998;32:385-392
    • (1998) Radiol Oncol , vol.32 , pp. 385-392
    • Garaj-Vrhovac, V.1    Kopjar, N.2
  • 99
    • 0033514497 scopus 로고    scopus 로고
    • Urinary cyclophosphamide excretion and micronuclei frequencies in periperal lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics
    • Burgaz S, Karahalil B, Bayrak P, Taşkin L, Yavuzaslan F, Bokesoy I, Anzion RBM, Bos RP, Platin N. Urinary cyclophosphamide excretion and micronuclei frequencies in periperal lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics. Mutat Res 1999;439:97-104.
    • (1999) Mutat Res , vol.439 , pp. 97-104
    • Burgaz, S.1    Karahalil, B.2    Bayrak, P.3    Taşkin, L.4    Yavuzaslan, F.5    Bokesoy, I.6    Anzion, R.B.M.7    Bos, R.P.8    Platin, N.9
  • 100
    • 0033899371 scopus 로고    scopus 로고
    • Evaluation of occupational genotoxic risk in a Brazilian hospital
    • Maluf SW, Erdtmann B. Evaluation of occupational genotoxic risk in a Brazilian hospital. Genetics Mol Biol 2000;23:485-488
    • (2000) Genetics Mol Biol , vol.23 , pp. 485-488
    • Maluf, S.W.1    Erdtmann, B.2
  • 101
    • 0034694109 scopus 로고    scopus 로고
    • Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay
    • Maluf SW, Erdtmann B. Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay. Mutat Res 2000;471:21-27
    • (2000) Mutat Res , vol.471 , pp. 21-27
    • Maluf, S.W.1    Erdtmann, B.2
  • 102
    • 0035909484 scopus 로고    scopus 로고
    • The genotoxic risk of hospital, pharmacy and medical personnel occupationally exposed to cytostatic drugs-evaluation by the micronucleus assay
    • Hessel H, Radon K, Pethran A, Maisch B, Grobmair S, Sautter I, Fruhmann G. The genotoxic risk of hospital, pharmacy and medical personnel occupationally exposed to cytostatic drugs-evaluation by the micronucleus assay. Mutat Res 2001;497:101-109
    • (2001) Mutat Res , vol.497 , pp. 101-109
    • Hessel, H.1    Radon, K.2    Pethran, A.3    Maisch, B.4    Grobmair, S.5    Sautter, I.6    Fruhmann, G.7
  • 103
    • 24044449663 scopus 로고    scopus 로고
    • Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points
    • Deng H, Zhang M, He J, Wu W, Jin L, Zheng W, Lou J, Wang B. Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points. Mutagenesis 2005;20:351-357
    • (2005) Mutagenesis , vol.20 , pp. 351-357
    • Deng, H.1    Zhang, M.2    He, J.3    Wu, W.4    Jin, L.5    Zheng, W.6    Lou, J.7    Wang, B.8
  • 104
    • 33745892089 scopus 로고    scopus 로고
    • Detecting the cytogenetic effects in workers occupationally exposed to vincristine with four genetic tests
    • Deng H, Lou J, Zhang M, Wu W, Jin L, Chen S, Zheng W, Wang B, He J. Detecting the cytogenetic effects in workers occupationally exposed to vincristine with four genetic tests. Mutat Res 2006;599:152-159
    • (2006) Mutat Res , vol.599 , pp. 152-159
    • Deng, H.1    Lou, J.2    Zhang, M.3    Wu, W.4    Jin, L.5    Chen, S.6    Zheng, W.7    Wang, B.8    He, J.9
  • 105
    • 23644431539 scopus 로고    scopus 로고
    • Genotoxic effects in a population of nurses handling antineoplastic drugs, and relationship with genetic polymorphisms in DNA repair enzymes
    • Laffon B, Teixeira JP, Silva S, Loureiro J, Torres J, Pasaro E, Mendez J, Mayan O. Genotoxic effects in a population of nurses handling antineoplastic drugs, and relationship with genetic polymorphisms in DNA repair enzymes. Am J Ind Med 2006;48:128-136
    • (2006) Am J Ind Med , vol.48 , pp. 128-136
    • Laffon, B.1    Teixeira, J.P.2    Silva, S.3    Loureiro, J.4    Torres, J.5    Pasaro, E.6    Mendez, J.7    Mayan, O.8
  • 106
    • 33847172197 scopus 로고    scopus 로고
    • Micronucleus induction and FISH analysis in buccal cells and lymphocytes of nurses handling antineoplastic drugs
    • Cavallo D, Ursini CL, Omodeo-Sale E, Iavicoli S. Micronucleus induction and FISH analysis in buccal cells and lymphocytes of nurses handling antineoplastic drugs. Mutat Res 2007;628:11-18
    • (2007) Mutat Res , vol.628 , pp. 11-18
    • Cavallo, D.1    Ursini, C.L.2    Omodeo-Sale, E.3    Iavicoli, S.4
  • 109
    • 61649097739 scopus 로고    scopus 로고
    • Occupational risk assessment of genotoxicity and oxidative stress in workers handling anti-neoplastic drugs during a working week
    • Rombaldi F, Cassini C, Salvador M, SaffiJ, Erdtmann B. Occupational risk assessment of genotoxicity and oxidative stress in workers handling anti-neoplastic drugs during a working week. Mutagenesis 2009;24:143-148
    • (2009) Mutagenesis , vol.24 , pp. 143-148
    • Rombaldi, F.1    Cassini, C.2    Salvador, M.3    Saffi, J.4    Erdtmann, B.5
  • 110
    • 0344959473 scopus 로고    scopus 로고
    • Assessment of DNA damage in nurses handling antineoplastic drugs by the alkaline COMET assay
    • Undeger U, Basaran N, Kars A, Guc D. Assessment of DNA damage in nurses handling antineoplastic drugs by the alkaline COMET assay. Mutat Res 1999;439:277-285
    • (1999) Mutat Res , vol.439 , pp. 277-285
    • Undeger, U.1    Basaran, N.2    Kars, A.3    Guc, D.4
  • 111
    • 0035172448 scopus 로고    scopus 로고
    • Application of the alkaline comet assay in human biomonitoring for genotoxicity: A study on Croatian medical personnel handling antineoplastic drugs
    • Kopjar N, Garaj-Vrhovac V. Application of the alkaline comet assay in human biomonitoring for genotoxicity: A study on Croatian medical personnel handling antineoplastic drugs. Mutagenesis 2001;16:71-78
    • (2001) Mutagenesis , vol.16 , pp. 71-78
    • Kopjar, N.1    Garaj-Vrhovac, V.2
  • 112
    • 36048941855 scopus 로고    scopus 로고
    • The study of DNA damage of peripheral lymphocytes in the nurses occupationally exposed to anticancer drugs in Chinese
    • Yang D, Xu S, Wang J. [The study of DNA damage of peripheral lymphocytes in the nurses occupationally exposed to anticancer drugs, in Chinese]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2002;20:197-199
    • (2002) Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi , vol.20 , pp. 197-199
    • Yang, D.1    Xu, S.2    Wang, J.3
  • 114
    • 33846034002 scopus 로고    scopus 로고
    • Genotoxic risks to nurses from contamination of the work environment with antineoplastic drugs in Japan
    • Yoshida J, Kosaka H, Tomioka K, Kumagai S. Genotoxic risks to nurses from contamination of the work environment with antineoplastic drugs in Japan. J Occup Health 2006;48:517-522
    • (2006) J Occup Health , vol.48 , pp. 517-522
    • Yoshida, J.1    Kosaka, H.2    Tomioka, K.3    Kumagai, S.4
  • 115
    • 40349114255 scopus 로고    scopus 로고
    • Assessment of DNA damage in Japanese nurses handling antineoplastic drugs by the comet assay
    • Sasaki M, Dakeishi M, Hoshi S, Ishii N, Murata K. Assessment of DNA damage in Japanese nurses handling antineoplastic drugs by the comet assay. J Occup Health 2008;50:7-12.
    • (2008) J Occup Health , vol.50 , pp. 7-12
    • Sasaki, M.1    Dakeishi, M.2    Hoshi, S.3    Ishii, N.4    Murata, K.5
  • 116
    • 69949101503 scopus 로고    scopus 로고
    • Assessment of Genotoxic damage in nurses occupationally exposed to anaesthetic gases or antineoplastic drugs by the comet assay
    • Izdes S, Sardas S, Kadioglu E, Kaymak C, Ozcagli E. Assessment of Genotoxic damage in nurses occupationally exposed to anaesthetic gases or antineoplastic drugs by the comet assay. J Occup Health 2009;51:283-286
    • (2009) J Occup Health , vol.51 , pp. 283-286
    • Izdes, S.1    Sardas, S.2    Kadioglu, E.3    Kaymak, C.4    Ozcagli, E.5
  • 117
    • 0016328318 scopus 로고
    • New Giemsa method for the differential staining of sister chromatids
    • Perry P, Wolff S. New Giemsa method for the differential staining of sister chromatids. Nature (London) 1974;251:156-158
    • (1974) Nature (London) , vol.251 , pp. 156-158
    • Perry, P.1    Wolff, S.2
  • 119
    • 0023947114 scopus 로고
    • Considerations for population monitoring using cytogenetic techniques
    • Carrano AV, Natarajan AT. Considerations for population monitoring using cytogenetic techniques. Mutat Res 1988;204:379-406.
    • (1988) Mutat Res , vol.204 , pp. 379-406
    • Carrano, A.V.1    Natarajan, A.T.2
  • 120
    • 0020663029 scopus 로고
    • Induction of sister chromatid exchanges and cell division delays in human lymphocytes by microsomal activation of benzene
    • Morimoto K. Induction of sister chromatid exchanges and cell division delays in human lymphocytes by microsomal activation of benzene. Cancer Res 1983;43:1330-1334
    • (1983) Cancer Res , vol.43 , pp. 1330-1334
    • Morimoto, K.1
  • 123
    • 0032907026 scopus 로고    scopus 로고
    • Analysis of correlated data in human biomonitoring studies. The case of high sister chromatid exchange frequency cells
    • Bonassi S, Fontana V, Ceppi M, Barale R, Bigeri A. Analysis of correlated data in human biomonitoring studies. The case of high sister chromatid exchange frequency cells. Mutat Res 1999;438:13-21.
    • (1999) Mutat Res , vol.438 , pp. 13-21
    • Bonassi, S.1    Fontana, V.2    Ceppi, M.3    Barale, R.4    Bigeri, A.5
  • 124
    • 0030773317 scopus 로고    scopus 로고
    • The nature of high frequency sister chromatid exchange cells (HFCs)
    • Ponzanelli I, Landi S, Bernacchi F, Barale R. The nature of high frequency sister chromatid exchange cells (HFCs). Mutagenesis 1997;12:329-333
    • (1997) Mutagenesis , vol.12 , pp. 329-333
    • Ponzanelli, I.1    Landi, S.2    Bernacchi, F.3    Barale, R.4
  • 125
    • 0026631051 scopus 로고
    • Genetic and environmental influences on baseline SCE
    • Hirsch BA, Sentz KK, McGue M. Genetic and environmental influences on baseline SCE. Environ Mol Mutagen 1992;20:2-11.
    • (1992) Environ Mol Mutagen , vol.20 , pp. 2-11
    • Hirsch, B.A.1    Sentz, K.K.2    McGue, M.3
  • 126
    • 0028288942 scopus 로고
    • Sister-chromatid exchanges and their distribution in human lymphocytes in relation to age, sex and smoking
    • Lazutka JR, Dedonyte V, Krapavickaite D. Sister-chromatid exchanges and their distribution in human lymphocytes in relation to age, sex and smoking. Mutat Res 1994;306:173-180
    • (1994) Mutat Res , vol.306 , pp. 173-180
    • Lazutka, J.R.1    Dedonyte, V.2    Krapavickaite, D.3
  • 128
    • 0023928522 scopus 로고
    • Chromosomal aberration and sister chromatid exchange frequencies in peripheral lymphocytes of a large human population sample
    • Bender MA, Preston J, Leonard RC, Pyatt BE, Gooch PC, Shelby MD. Chromosomal aberration and sister chromatid exchange frequencies in peripheral lymphocytes of a large human population sample. Mutat Res 1988;204:421-433
    • (1988) Mutat Res , vol.204 , pp. 421-433
    • Bender, M.A.1    Preston, J.2    Leonard, R.C.3    Pyatt, B.E.4    Gooch, P.C.5    Shelby, M.D.6
  • 129
    • 0027716484 scopus 로고
    • Variability in chromosome aberrations, sister chromatid exchanges, and mitogen-induced blastogenesis in peripheral lymphocytes from control individuals
    • Anderson D, Francis AJ, Godbert P, Jenkinson PC, Butterworth KR. Variability in chromosome aberrations, sister chromatid exchanges, and mitogen-induced blastogenesis in peripheral lymphocytes from control individuals. Environ Health Persp 1993;101(Suppl 3):83-88
    • (1993) Environ Health Persp , vol.101 , Issue.SUPPL. 3 , pp. 83-88
    • Anderson, D.1    Francis, A.J.2    Godbert, P.3    Jenkinson, P.C.4    Butterworth, K.R.5
  • 130
    • 0022575310 scopus 로고
    • Higher incidence of spontaneous sister-chromatid exchanges (SCEs) and X-ray-induced chromosome aberrations in peripheral blood lymphocytes during pregnancy
    • Sharma T, Das BC. Higher incidence of spontaneous sister-chromatid exchanges (SCEs) and X-ray-induced chromosome aberrations in peripheral blood lymphocytes during pregnancy. Mutat Res 1986;174:27-33.
    • (1986) Mutat Res , vol.174 , pp. 27-33
    • Sharma, T.1    Das, B.C.2
  • 131
    • 0020077844 scopus 로고
    • In vivo and in vitro effects of cigarette smoke on chromosomal damage and sister chromatid exchange in human peripheral blood lymphocytes
    • Vijayalaxmi, Evans HJ. In vivo and in vitro effects of cigarette smoke on chromosomal damage and sister chromatid exchange in human peripheral blood lymphocytes. Mutat Res 1982;92:321-332
    • (1982) Mutat Res , vol.92 , pp. 321-332
    • Vijayalaxmi1    Evans, H.J.2
  • 132
    • 0020077269 scopus 로고
    • Doubleblind study on the effect of cigarette smoking on the chromosomes of human peripheral blood lymphocytes in vivo
    • Obe G, Vogt HJ, Madle S, Fahning A, Heller WD. Doubleblind study on the effect of cigarette smoking on the chromosomes of human peripheral blood lymphocytes in vivo. Mutat Res 1982;92:309-319
    • (1982) Mutat Res , vol.92 , pp. 309-319
    • Obe, G.1    Vogt, H.J.2    Madle, S.3    Fahning, A.4    Heller, W.D.5
  • 133
    • 0023884175 scopus 로고
    • Variation in human lymphocyte sister-chromatid exchange frequency: Result of a long-term longitudinal study
    • Tucker JD, Ashworth LK, Johnston GR, Allen NA, Carrano AV. Variation in human lymphocyte sister-chromatid exchange frequency: result of a long-term longitudinal study. Mutat Res 1988;204:435-444
    • (1988) Mutat Res , vol.204 , pp. 435-444
    • Tucker, J.D.1    Ashworth, L.K.2    Johnston, G.R.3    Allen, N.A.4    Carrano, A.V.5
  • 134
    • 0024216838 scopus 로고
    • Increased sister chromatid exchange associated with smoking and coffee consumption
    • Reidy JA, Annest JL, Chen ATL, Welty TK. Increased sister chromatid exchange associated with smoking and coffee consumption. Environ Mol Mutagen 1988;12:311-318
    • (1988) Environ Mol Mutagen , vol.12 , pp. 311-318
    • Reidy, J.A.1    Annest, J.L.2    Chen, A.T.L.3    Welty, T.K.4
  • 136
    • 0036157657 scopus 로고    scopus 로고
    • Cytogenetic analysis of peripheral blood lymphocytes of children treated with nitrofurantion for recurrent urinary tract infection
    • Slapšyte G, Jankauskiene A, Mieraiskiene J, Lazutka JR. Cytogenetic analysis of peripheral blood lymphocytes of children treated with nitrofurantion for recurrent urinary tract infection. Mutagenesis 2002;17:31-35
    • (2002) Mutagenesis , vol.17 , pp. 31-35
    • Slapšyte, G.1    Jankauskiene, A.2    Mieraiskiene, J.3    Lazutka, J.R.4
  • 137
    • 0344507187 scopus 로고    scopus 로고
    • Low sensitivity of the sister chromatid exchange assay to detect the genotoxic effects of radioiodine therapy
    • Gutierrez S, Carbonell E, Galofre P, Creus A, Marcos R. Low sensitivity of the sister chromatid exchange assay to detect the genotoxic effects of radioiodine therapy. Mutagenesis 1999;14:221-226
    • (1999) Mutagenesis , vol.14 , pp. 221-226
    • Gutierrez, S.1    Carbonell, E.2    Galofre, P.3    Creus, A.4    Marcos, R.5
  • 138
    • 0021335867 scopus 로고
    • The effects of diagnostic ultrasound on sister chromatid exchange frequencies: A review of the recent literature
    • Jacobson-Kram D. The effects of diagnostic ultrasound on sister chromatid exchange frequencies: a review of the recent literature. J Clin Ultrasound 1984;12:5-10.
    • (1984) J Clin Ultrasound , vol.12 , pp. 5-10
    • Jacobson-Kram, D.1
  • 139
    • 0033864764 scopus 로고    scopus 로고
    • Cytogenetic monitoring of cardiology unit hospital workers exposed to ultrasound
    • Garaj-Vrhovac V, Kopjar N. Cytogenetic monitoring of cardiology unit hospital workers exposed to ultrasound. J Appl Toxicol 2000;20:259-264
    • (2000) J Appl Toxicol , vol.20 , pp. 259-264
    • Garaj-Vrhovac, V.1    Kopjar, N.2
  • 140
    • 0034673251 scopus 로고    scopus 로고
    • Sister chromatid exchange rate from pleural fluid cells in patient with malignant mesothelioma
    • Atalay F, Baltaci V, Alpas I, Savas I, Atikcan S, Balci S. Sister chromatid exchange rate from pleural fluid cells in patient with malignant mesothelioma. Mutat Res 2000;465:159-163
    • (2000) Mutat Res , vol.465 , pp. 159-163
    • Atalay, F.1    Baltaci, V.2    Alpas, I.3    Savas, I.4    Atikcan, S.5    Balci, S.6
  • 141
    • 0034667257 scopus 로고    scopus 로고
    • Sister chromatid exchanges in peripheral lymphocytes from women with carcinoma of the uterine cervix
    • Cortes-Guttierez EI, Cerda-Flores RM, Leal-Garza CH. Sister chromatid exchanges in peripheral lymphocytes from women with carcinoma of the uterine cervix. Cancer Genet Cytogenet 2000;122:121-123
    • (2000) Cancer Genet Cytogenet , vol.122 , pp. 121-123
    • Cortes-Guttierez, E.I.1    Cerda-Flores, R.M.2    Leal-Garza, C.H.3
  • 143
    • 0029820894 scopus 로고    scopus 로고
    • Cytogenetic analysis in peripheral lymphocytes of cancer patients treated with cytostatic drugs: Results from an EC Collaborative Study
    • Carbonell E, Demopoulos NA, Stefanou G, Psaraki K, Parry EM, Marcos R. Cytogenetic analysis in peripheral lymphocytes of cancer patients treated with cytostatic drugs: Results from an EC Collaborative Study. Anticancer Drugs 1996;7:514-519
    • (1996) Anticancer Drugs , vol.7 , pp. 514-519
    • Carbonell, E.1    Demopoulos, N.A.2    Stefanou, G.3    Psaraki, K.4    Parry, E.M.5    Marcos, R.6
  • 144
    • 34447307400 scopus 로고    scopus 로고
    • Cytogenetic outcomes of adjuvant chemotherapy in non-target cells of breast cancer patients
    • Kopjar N, Milas I, Garaj-Vrhovac V, Gamulin M. Cytogenetic outcomes of adjuvant chemotherapy in non-target cells of breast cancer patients. Hum Exp Toxicol 2007;26:391-399
    • (2007) Hum Exp Toxicol , vol.26 , pp. 391-399
    • Kopjar, N.1    Milas, I.2    Garaj-Vrhovac, V.3    Gamulin, M.4
  • 146
    • 0029977143 scopus 로고    scopus 로고
    • Ramalho at Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens
    • Natarajan AT, Boei JJ, Darroudi F, Van Diemen PCM, Dulout F, Hande MP, Ramalho AT Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens. Environ Health Persp 1996;104(Suppl 3):445-448
    • (1996) Environ Health Persp , vol.104 , Issue.SUPPL. 3 , pp. 445-448
    • Natarajan, A.T.1    Boei, J.J.2    Darroudi, F.3    Van Diemen, P.C.M.4    Dulout, F.5    Hande, M.P.6
  • 148
    • 0004094379 scopus 로고    scopus 로고
    • International Atomic Energy Agency (IAEA). Technical Report Series no. Vienna: IAEA
    • International Atomic Energy Agency (IAEA). Cytogenetic Analysis for Radiation Dose Assessment. Technical Report Series no. Vienna: IAEA; 2001.
    • (2001) Cytogenetic Analysis for Radiation Dose Assessment
  • 149
    • 33745818573 scopus 로고    scopus 로고
    • Evaluation of DNA damage in the white blood cells of healthy human volunteers using the alkaline comet assay and the chromosome aberration test
    • Kopjar N, Želježić D, Garaj-Vrhovac V. Evaluation of DNA damage in the white blood cells of healthy human volunteers using the alkaline comet assay and the chromosome aberration test. Acta Biochim Pol 2006;53:321-336
    • (2006) Acta Biochim Pol , vol.53 , pp. 321-336
    • Kopjar, N.1    Želježić, D.2    Garaj-Vrhovac, V.3
  • 151
    • 0037427878 scopus 로고    scopus 로고
    • HUMN project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
    • Fenech M, Chang WP, Kirsch-Volders M, Holland N, Bonassi S, Zeiger E. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 2003;534:65-75.
    • (2003) Mutat Res , vol.534 , pp. 65-75
    • Fenech, M.1    Chang, W.P.2    Kirsch-Volders, M.3    Holland, N.4    Bonassi, S.5    Zeiger, E.6
  • 152
    • 0032920117 scopus 로고    scopus 로고
    • Biomonitoring using accessible human cells for exposure and health risk assessment
    • Salama S, Serrana M, Au WW. Biomonitoring using accessible human cells for exposure and health risk assessment. Mutat Res 1999;436:99-112.
    • (1999) Mutat Res , vol.436 , pp. 99-112
    • Salama, S.1    Serrana, M.2    Au, W.W.3
  • 153
    • 47849123302 scopus 로고    scopus 로고
    • The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps
    • Holland N, Bolognesi C, Kirsch-Volders M, Bonassi S, Zeiger E, Knasmueller S, Fenech M. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps. Mutat Res 2008;659:93-108.
    • (2008) Mutat Res , vol.659 , pp. 93-108
    • Holland, N.1    Bolognesi, C.2    Kirsch-Volders, M.3    Bonassi, S.4    Zeiger, E.5    Knasmueller, S.6    Fenech, M.7
  • 154
    • 0027722263 scopus 로고
    • Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens
    • Norppa H, Luomahaara S, Heikanen H, Roth S, Sorsa M, Renzi L, Lindholm C. Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens. Environ Health Persp 1993;101(Suppl 3):139-143
    • (1993) Environ Health Persp , vol.101 , Issue.SUPPL. 3 , pp. 139-143
    • Norppa, H.1    Luomahaara, S.2    Heikanen, H.3    Roth, S.4    Sorsa, M.5    Renzi, L.6    Lindholm, C.7
  • 155
    • 0030805031 scopus 로고    scopus 로고
    • The in vitro micronucleus test - A multiendpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction
    • Kirsch Volders M, Elhajouji A, Cundari E, Vanhumelen P. The in vitro micronucleus test - a multiendpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat Res 1997;392:19-30.
    • (1997) Mutat Res , vol.392 , pp. 19-30
    • Kirsch Volders, M.1    Elhajouji, A.2    Cundari, E.3    Vanhumelen, P.4
  • 156
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech M, Morley AA. Measurement of micronuclei in lymphocytes. Mutat Res 1985;147:29-36.
    • (1985) Mutat Res , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 157
    • 0038393167 scopus 로고    scopus 로고
    • What do human micronuclei contain?
    • Norppa H, Falck GCM. What do human micronuclei contain? Mutagenesis 2003;18:221-233
    • (2003) Mutagenesis , vol.18 , pp. 221-233
    • Norppa, H.1    Falck, G.C.M.2
  • 159
    • 84907126206 scopus 로고
    • Cbanding as a simple tool to discriminate micronuclei induced by clastogens and aneugens
    • Verschaeve L, Vanderkerken M, Kirsch-Volders M. Cbanding as a simple tool to discriminate micronuclei induced by clastogens and aneugens. Stain Technol 1988;63:351-354
    • (1988) Stain Technol , vol.63 , pp. 351-354
    • Verschaeve, L.1    Vanderkerken, M.2    Kirsch-Volders, M.3
  • 160
    • 33751119273 scopus 로고    scopus 로고
    • Chromosomal changes: Induction, detection methods and applicability in human biomonitoring
    • Mateuca R, Lombaert N, Aka PV, Decodier I, Kirsch-Volders M. Chromosomal changes: induction, detection methods and applicability in human biomonitoring. Biochemie 2006;88:1515-1531
    • (2006) Biochemie , vol.88 , pp. 1515-1531
    • Mateuca, R.1    Lombaert, N.2    Aka, P.V.3    Decodier, I.4    Kirsch-Volders, M.5
  • 161
    • 0027497435 scopus 로고
    • The cytokinesis-block micronucleus technique: A detailed description of
    • Fenech M. The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human population. Mutat Res 1993;285:35-44.
    • (1993) Mutat Res , vol.285 , pp. 35-44
    • Fenech, M.1
  • 162
    • 0027930347 scopus 로고
    • Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesisblocked lymphocytes
    • Fenech M, Neville S, Rinaldi J. Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesisblocked lymphocytes. Mutat Res 1994;313:203-207
    • (1994) Mutat Res , vol.313 , pp. 203-207
    • Fenech, M.1    Neville, S.2    Rinaldi, J.3
  • 163
    • 0029968510 scopus 로고    scopus 로고
    • Activation status of the X chromosome in human micronucleated lymphocytes
    • Tucker JD, Nath J, Hando JC. Activation status of the X chromosome in human micronucleated lymphocytes. Hum Genet 1996;97:471-475
    • (1996) Hum Genet , vol.97 , pp. 471-475
    • Tucker, J.D.1    Nath, J.2    Hando, J.C.3
  • 164
    • 0024523360 scopus 로고
    • Kinetochore detection in micronuclei: An alternative method for measuring chromosome loss
    • Fenech M, Morley AA. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. Mutagenesis 1989;4:98-104.
    • (1989) Mutagenesis , vol.4 , pp. 98-104
    • Fenech, M.1    Morley, A.A.2
  • 165
    • 0027722263 scopus 로고
    • Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens
    • Norppa H, Luomahaara S, Heikanen H, Roth S, Sorsa M, Renzi L, Lindholm C. Micronucleus assay in lymphocytes as a tool to biomonitor human exposure to aneuploidogens and clastogens. Environ Health Persp 1993;101(Suppl 3):139-143
    • (1993) Environ Health Persp , vol.101 , Issue.SUPPL. 3 , pp. 139-143
    • Norppa, H.1    Luomahaara, S.2    Heikanen, H.3    Roth, S.4    Sorsa, M.5    Renzi, L.6    Lindholm, C.7
  • 167
    • 0033645325 scopus 로고    scopus 로고
    • Chromosomal aberrations and micronuclei in lymphocytes of patients before and after exposure to antituberculosis drugs
    • Masjedi MR, Heidary A, Mohammadi F, Velayati AA, Dokouhaki P. Chromosomal aberrations and micronuclei in lymphocytes of patients before and after exposure to antituberculosis drugs. Mutagenesis 2000;15:489-494
    • (2000) Mutagenesis , vol.15 , pp. 489-494
    • Masjedi, M.R.1    Heidary, A.2    Mohammadi, F.3    Velayati, A.A.4    Dokouhaki, P.5
  • 168
    • 0037323624 scopus 로고    scopus 로고
    • Effect of various doses of gestogens on micronuclei frequency in human peripheral blood lymphocytes of pregnant women
    • Milošević-Dordević O, Grujićić D, Marinković D, Arsenijević S, Banković S. Effect of various doses of gestogens on micronuclei frequency in human peripheral blood lymphocytes of pregnant women. Hum Reprod 2003;18:433-436
    • (2003) Hum Reprod , vol.18 , pp. 433-436
    • Milošević-Dordević, O.1    Grujićić, D.2    Marinković, D.3    Arsenijević, S.4    Banković, S.5
  • 169
    • 0018855802 scopus 로고
    • Cytogenetic effects of contrast material in patients undergoing excretory urography
    • Cochran ST, Khodadoust A, Norman A. Cytogenetic effects of contrast material in patients undergoing excretory urography. Radiology 1980;136:43-46
    • (1980) Radiology , vol.136 , pp. 43-46
    • Cochran, S.T.1    Khodadoust, A.2    Norman, A.3
  • 170
    • 0021207732 scopus 로고
    • Effects of age, sex and diagnostic X-rays on chromosome damage
    • Norman A, Cochran S, Bass D, Roe D. Effects of age, sex and diagnostic X-rays on chromosome damage. Int J Radiat Biol 1984;46:317-321
    • (1984) Int J Radiat Biol , vol.46 , pp. 317-321
    • Norman, A.1    Cochran, S.2    Bass, D.3    Roe, D.4
  • 171
    • 0026020752 scopus 로고
    • Increased frequency of micronuclei in B and T8 lymphocytes from smokers
    • Larramendy ML, Knuutila S. Increased frequency of micronuclei in B and T8 lymphocytes from smokers. Mutat Res 1991;259:189-195
    • (1991) Mutat Res , vol.259 , pp. 189-195
    • Larramendy, M.L.1    Knuutila, S.2
  • 172
    • 0037339166 scopus 로고    scopus 로고
    • Effect of smoking habit on the frequency of micronuclei in human lymphocytes: Results from the Human MicroNucleus project
    • The HUMN collaborative group
    • Bonassi S, Neri M, Lando C, Ceppi M, Lin Y, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Fenech M, The HUMN collaborative group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat Res 2003;543:155-166
    • (2003) Mutat Res , vol.543 , pp. 155-166
    • Bonassi, S.1    Neri, M.2    Lando, C.3    Ceppi, M.4    Lin, Y.5    Chang, W.P.6    Holland, N.7    Kirsch-Volders, M.8    Zeiger, E.9    Fenech, M.10
  • 174
    • 0033067120 scopus 로고    scopus 로고
    • Single cell electrophoresis assay: Methodology and applications
    • Rojas E, Lopez MC, Valverde M. Single cell electrophoresis assay: methodology and applications. J Chrom B 1999;722:225-254
    • (1999) J Chrom B , vol.722 , pp. 225-254
    • Rojas, E.1    Lopez, M.C.2    Valverde, M.3
  • 175
    • 0034693836 scopus 로고    scopus 로고
    • Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis
    • Singh NP. Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis. Mutat Res 2000;455:111-127
    • (2000) Mutat Res , vol.455 , pp. 111-127
    • Singh, N.P.1
  • 176
    • 0029129669 scopus 로고
    • DNA damage detection in man after radiation exposure - The comet assay - Its possible application for human monitoring
    • Plappert U, Raddatz K, Roth S, Fliedner TM. DNA damage detection in man after radiation exposure - the comet assay - its possible application for human monitoring. Stem Cells 1995:13:215-222
    • (1995) Stem Cells , vol.13 , pp. 215-222
    • Plappert, U.1    Raddatz, K.2    Roth, S.3    Fliedner, T.M.4
  • 177
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider LL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, L.L.4
  • 178
    • 0032959983 scopus 로고    scopus 로고
    • Applications of the comet assay in radiobiology
    • Olive PL. Applications of the comet assay in radiobiology. Int J Radiat Biol 1999;75:395-405.
    • (1999) Int J Radiat Biol , vol.75 , pp. 395-405
    • Olive, P.L.1
  • 179
    • 0030014152 scopus 로고    scopus 로고
    • Oxidative damage to DNA: Do we have a reliable marker?
    • Collins A, Dušinska M, Gedik C, Štetina R. Oxidative damage to DNA: Do we have a reliable marker? Environ Health Persp 1996;104(Suppl 3):465-469
    • (1996) Environ Health Persp , vol.104 , Issue.SUPPL. 3 , pp. 465-469
    • Collins, A.1    Dušinska, M.2    Gedik, C.3    Štetina, R.4
  • 180
    • 0025270234 scopus 로고
    • Heterogeneity in radiationinduced DNA damage and repair in tumor and normal cells using the "comet" assay
    • Olive PL, Banath JP, Durand RE. Heterogeneity in radiationinduced DNA damage and repair in tumor and normal cells using the "comet" assay. Radiat Res 1990;122:86-94.
    • (1990) Radiat Res , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 181
    • 0036351602 scopus 로고    scopus 로고
    • Modified neutral comet assay for human lymphocytes
    • Wojewodzka M, Grádzka I, Buraczewska I. Modified neutral comet assay for human lymphocytes. Nukleonika 2002;47:1-5.
    • (2002) Nukleonika , vol.47 , pp. 1-5
    • Wojewodzka, M.1    Grádzka, I.2    Buraczewska, I.3
  • 182
    • 0033855389 scopus 로고    scopus 로고
    • Mechanisms of DNA double strand break repair and their potential to induce chromosomal aberrations
    • Pfeiffer P, Goedecke W, Obe G. Mechanisms of DNA double strand break repair and their potential to induce chromosomal aberrations. Mutagenesis 2000;15:289-302.
    • (2000) Mutagenesis , vol.15 , pp. 289-302
    • Pfeiffer, P.1    Goedecke, W.2    Obe, G.3
  • 183
    • 0345276655 scopus 로고    scopus 로고
    • Sensitivity of the FPG protein towards alkylation damage in the comet assay
    • Speit G, Schutz P, Bonzheim I, Trenz K, Hoffmann H. Sensitivity of the FPG protein towards alkylation damage in the comet assay. Toxicol Lett 2004;146:151-158
    • (2004) Toxicol Lett , vol.146 , pp. 151-158
    • Speit, G.1    Schutz, P.2    Bonzheim, I.3    Trenz, K.4    Hoffmann, H.5
  • 184
    • 33745107265 scopus 로고    scopus 로고
    • HOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII
    • Smith CC, O'Donovan MR, Martin EA. hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII. Mutagenesis 2006;21:185-190
    • (2006) Mutagenesis , vol.21 , pp. 185-190
    • Smith, C.C.1    O'Donovan, M.R.2    Martin, E.A.3
  • 185
    • 0032584399 scopus 로고    scopus 로고
    • Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (comet) assay. Relationship between the onset of DNA damage and the characteristics of mutagens
    • Miyamae Y, Zaizen K, Ohara K, Mine Y, Sasaki YF. Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (comet) assay. Relationship between the onset of DNA damage and the characteristics of mutagens. Mutat Res 1998;415:229-235
    • (1998) Mutat Res , vol.415 , pp. 229-235
    • Miyamae, Y.1    Zaizen, K.2    Ohara, K.3    Mine, Y.4    Sasaki, Y.F.5
  • 186
    • 0002987035 scopus 로고
    • The single cell gel / comet assay: A microgel electrophoretic technique for the detection of DNA damage and repair in individual cells
    • U: Phillips DH, Vennit S, urednici. Oxford: Bioscientific, str.
    • Tice RR. The single cell gel / comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells. U: Phillips DH, Vennit S, urednici. Environmental Mutagenesis. Oxford: Bioscientific; 1995. str. 315-339
    • (1995) Environmental Mutagenesis , pp. 315-339
    • Tice, R.R.1
  • 187
    • 0026718782 scopus 로고
    • Repair of DNA damage induced by oxygen radicals in human non-proliferating and proliferating lymphocytes
    • Kaminskas E, Li JC. Repair of DNA damage induced by oxygen radicals in human non-proliferating and proliferating lymphocytes. Mutat Res 1992;274:103-110
    • (1992) Mutat Res , vol.274 , pp. 103-110
    • Kaminskas, E.1    Li, J.C.2
  • 188
    • 0030986996 scopus 로고    scopus 로고
    • The cell cycle positions Influence DNA migration as measured with the alkaline comet assay in stimulated human lymphocytes
    • Šalagović J, Maes A, Van Gorp U, Verschaeve L, Kalina I. The cell cycle positions Influence DNA migration as measured with the alkaline comet assay in stimulated human lymphocytes. Folia Biol (Praha) 1997;43:79-82.
    • (1997) Folia Biol (Praha) , vol.43 , pp. 79-82
    • Šalagović, J.1    Maes, A.2    Van Gorp, U.3    Verschaeve, L.4    Kalina, I.5
  • 190
    • 0029864861 scopus 로고    scopus 로고
    • Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay
    • Fortini P, Raspaglio G, Falchi M, Dogliotti E. Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay. Mutagenesis 1996;11:169-175
    • (1996) Mutagenesis , vol.11 , pp. 169-175
    • Fortini, P.1    Raspaglio, G.2    Falchi, M.3    Dogliotti, E.4
  • 191
    • 0028284199 scopus 로고
    • Microgel electrophoresis assay (comet test) and SCE analysis in human lymphocytes from 100 normal subjects
    • Betti C, Davini T, Giannessi L, Loprieno N, Barale R. Microgel electrophoresis assay (comet test) and SCE analysis in human lymphocytes from 100 normal subjects. Mutat Res 1994;307:323-333
    • (1994) Mutat Res , vol.307 , pp. 323-333
    • Betti, C.1    Davini, T.2    Giannessi, L.3    Loprieno, N.4    Barale, R.5
  • 192
    • 0344301939 scopus 로고    scopus 로고
    • Application of the comet assay for monitoring DNA damage in workers exposed to chronic low-dose irradiation. I. Strand breakage
    • Wojewodzka M, Kruszewski M, Iwanenko T, Collins AR, Szumiel I. Application of the comet assay for monitoring DNA damage in workers exposed to chronic low-dose irradiation. I. Strand breakage. Mutat Res 1998;416:21-35.
    • (1998) Mutat Res , vol.416 , pp. 21-35
    • Wojewodzka, M.1    Kruszewski, M.2    Iwanenko, T.3    Collins, A.R.4    Szumiel, I.5
  • 194
    • 0037179491 scopus 로고    scopus 로고
    • Gender-related differences in basal DNA damage in lymphocytes of a healthy Indian population using the alkaline comet assay
    • Bajpayee M, Dhawan A, Parmar D, Kumar Pendey A, Mathur N, Seth PK. Gender-related differences in basal DNA damage in lymphocytes of a healthy Indian population using the alkaline comet assay. Mutat Res 2002;520:83-91.
    • (2002) Mutat Res , vol.520 , pp. 83-91
    • Bajpayee, M.1    Dhawan, A.2    Parmar, D.3    Kumar Pendey, A.4    Mathur, N.5    Seth, P.K.6
  • 198
    • 0031820168 scopus 로고    scopus 로고
    • Effects of smoking and aging on oxidative DNA damage of human lymphocytes
    • Piperakis SM, Visvardis EE, Sagnou M, Tassiou AM. Effects of smoking and aging on oxidative DNA damage of human lymphocytes. Carcinogenesis 1998;19:695-698
    • (1998) Carcinogenesis , vol.19 , pp. 695-698
    • Piperakis, S.M.1    Visvardis, E.E.2    Sagnou, M.3    Tassiou, A.M.4
  • 199
    • 33745818573 scopus 로고    scopus 로고
    • Evaluation of DNA damage in the white blood cells of healthy human volunteers using the alkaline comet assay and the chromosome aberration test
    • Kopjar N, Želježić D, Garaj-Vrhovac V. Evaluation of DNA damage in the white blood cells of healthy human volunteers using the alkaline comet assay and the chromosome aberration test. Acta Biochim Pol 2006;53:321-336
    • (2006) Acta Biochim Pol , vol.53 , pp. 321-336
    • Kopjar, N.1    Želježić, D.2    Garaj-Vrhovac, V.3
  • 200
    • 0032968102 scopus 로고    scopus 로고
    • Alkaline single cell gel electrophoresis and human biomonitoring for genotoxicity: A study on subjects with residential exposure to radon
    • Hellman B, Friis L, Vaghef H, Edling C. Alkaline single cell gel electrophoresis and human biomonitoring for genotoxicity: a study on subjects with residential exposure to radon. Mutat Res 1999;442:121-132
    • (1999) Mutat Res , vol.442 , pp. 121-132
    • Hellman, B.1    Friis, L.2    Vaghef, H.3    Edling, C.4
  • 201
    • 18244374004 scopus 로고    scopus 로고
    • Sunlight-induced DNA damage in human mononuclear cells
    • Moller P, Wallin H, Holst E, Knudsen LE. Sunlight-induced DNA damage in human mononuclear cells. FASEB J 2002;16:45-53.
    • (2002) FASEB J , vol.16 , pp. 45-53
    • Moller, P.1    Wallin, H.2    Holst, E.3    Knudsen, L.E.4
  • 202
    • 36148986766 scopus 로고    scopus 로고
    • Seasonal variations in spontaneous levels of DNA damage; Implication in the risk assessment of environmental chemicals
    • Verschaeve L, Koppen G, Gorp UV, Schoeters G, Jacobs G, Zwijzen C. Seasonal variations in spontaneous levels of DNA damage; implication in the risk assessment of environmental chemicals. J Appl Toxicol 2007;27:612-620
    • (2007) J Appl Toxicol , vol.27 , pp. 612-620
    • Verschaeve, L.1    Koppen, G.2    Gorp, U.V.3    Schoeters, G.4    Jacobs, G.5    Zwijzen, C.6
  • 203
    • 0344109582 scopus 로고    scopus 로고
    • The alkaline single-cell gel electrophoresis (SCGE) assay applied to the analysis of radiation-induced DNA damage in thyroid cancer patients treated with 131I
    • Gutierrez S, Carbonell E, Galofre P, Creus A, Marcos R. The alkaline single-cell gel electrophoresis (SCGE) assay applied to the analysis of radiation-induced DNA damage in thyroid cancer patients treated with 131I. Mutat Res 1998;413:111-119
    • (1998) Mutat Res , vol.413 , pp. 111-119
    • Gutierrez, S.1    Carbonell, E.2    Galofre, P.3    Creus, A.4    Marcos, R.5
  • 205
    • 0037180356 scopus 로고    scopus 로고
    • Assessment of DNA damage in women using oral contraceptives
    • Biri A, Civelek E, Karahalil B, Sardaş S. Assessment of DNA damage in women using oral contraceptives. Mutat Res 2002;521:113-119
    • (2002) Mutat Res , vol.521 , pp. 113-119
    • Biri, A.1    Civelek, E.2    Karahalil, B.3    Sardaş, S.4
  • 208
    • 0031971964 scopus 로고    scopus 로고
    • Seasonal variation of DNA damage and repair in patients with non-melanoma skin cancer and referents with and without psoriasis
    • Moller P, Knudsen LE, Frentz G, Dybdahl M, Wallin H, Nexo BA. Seasonal variation of DNA damage and repair in patients with non-melanoma skin cancer and referents with and without psoriasis. Mutat Res 1998;407:25-34.
    • (1998) Mutat Res , vol.407 , pp. 25-34
    • Moller, P.1    Knudsen, L.E.2    Frentz, G.3    Dybdahl, M.4    Wallin, H.5    Nexo, B.A.6
  • 212
    • 16644388723 scopus 로고    scopus 로고
    • The comet-FISH technique: A tool for detection of specific DNA damage and repair
    • Rapp A, Hausmann M, Greulich KO. The comet-FISH technique: a tool for detection of specific DNA damage and repair. Methods Mol Biol 2005;291:107-119
    • (2005) Methods Mol Biol , vol.291 , pp. 107-119
    • Rapp, A.1    Hausmann, M.2    Greulich, K.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.