메뉴 건너뛰기




Volumn 28, Issue 3, 2007, Pages 625-631

An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans

(24)  Bonassi, Stefano a   Znaor, Ariana b   Ceppi, Marcello a   Lando, Cecilia a   Chang, Wushou Peter c   Holland, Nina d   Kirsch Volders, Micheline e   Zeiger, Errol f   Ban, Sadayuki g,u   Barale, Roberto h   Bigatti, Maria Paola i   Bolognesi, Claudia a   Cebulska Wasilewska, Antonina j   Fabianova, Eleonora k   Fucic, Alexandra l   Hagmar, Lars m   Joksic, Gordana n   Martelli, Antonietta o   Migliore, Lucia h   Mirkova, Ekaterina p   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CARCINOGENESIS; CHROMOSOME ANALYSIS; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DISEASE MARKER; FEMALE; GENETIC SCREENING; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; PERIPHERAL LYMPHOCYTE; PREDICTION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; UROGENITAL TRACT CANCER;

EID: 34047154552     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl177     Document Type: Article
Times cited : (880)

References (44)
  • 1
    • 0032785259 scopus 로고    scopus 로고
    • The HUman MicroNucleus project - An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
    • Fenech,M., Holland,N., Chang,W.P., Zeiger,E. and Bonassi,S. (1999) The HUman MicroNucleus project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat. Res., 428, 271-283.
    • (1999) Mutat. Res. , vol.428 , pp. 271-283
    • Fenech, M.1    Holland, N.2    Chang, W.P.3    Zeiger, E.4    Bonassi, S.5
  • 2
    • 0346726185 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes
    • Kimura,M., Umegaki,K., Higuchi,M., Thomas,P. and Fenech,M. (2004) Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes. J. Nutr., 134, 48-56.
    • (2004) J. Nutr. , vol.134 , pp. 48-56
    • Kimura, M.1    Umegaki, K.2    Higuchi, M.3    Thomas, P.4    Fenech, M.5
  • 4
    • 0034066102 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
    • Umegaki,K. and Fenech,M. (2000) Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis, 15, 261-269.
    • (2000) Mutagenesis , vol.15 , pp. 261-269
    • Umegaki, K.1    Fenech, M.2
  • 6
    • 0025067982 scopus 로고
    • Dietary factors affecting spontaneous chromosomal damage in man
    • MacGregor,J.T. (1990) Dietary factors affecting spontaneous chromosomal damage in man. Prog. Clin. Biol. Res., 347, 139-153.
    • (1990) Prog. Clin. Biol. Res. , vol.347 , pp. 139-153
    • MacGregor, J.T.1
  • 7
    • 0034936018 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary lymphocyte DNA in vitro
    • (Accelerated Paper)
    • Crott,J.W., Mashiyama,S.T., Ames,B.N. and Fenech,M. (2001) MTHFR C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary lymphocyte DNA in vitro. (Accelerated Paper). Carcinogenesis, 22, 1019-1025.
    • (2001) Carcinogenesis , vol.22 , pp. 1019-1025
    • Crott, J.W.1    Mashiyama, S.T.2    Ames, B.N.3    Fenech, M.4
  • 8
    • 19844378446 scopus 로고    scopus 로고
    • Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, b-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability - Results from a dietary intake and micronucleus index survey in South Australia
    • Fenech,M., Baghurst,P., Luderer,W., Turner,J., Record,S., Ceppi,M. and Bonassi,S. (2005) Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, b-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability - results from a dietary intake and micronucleus index survey in South Australia. Carcinogenesis, 26, 991-999.
    • (2005) Carcinogenesis , vol.26 , pp. 991-999
    • Fenech, M.1    Baghurst, P.2    Luderer, W.3    Turner, J.4    Record, S.5    Ceppi, M.6    Bonassi, S.7
  • 9
    • 0037112246 scopus 로고    scopus 로고
    • Chromosomal biomarkers of genomic instability relevant to cancer
    • Fenech,M. (2002) Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov. Today, 22, 1128-1137.
    • (2002) Drug Discov. Today , vol.22 , pp. 1128-1137
    • Fenech, M.1
  • 10
    • 0037427878 scopus 로고    scopus 로고
    • HUMN Project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
    • Fenech,M., Chang,W.P., Kirsch-Volders,M., Holland,N., Bonassi,S. and Zeiger,E. (2003) HUMN Project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res., 534, 65-75.
    • (2003) Mutat. Res. , vol.534 , pp. 65-75
    • Fenech, M.1    Chang, W.P.2    Kirsch-Volders, M.3    Holland, N.4    Bonassi, S.5    Zeiger, E.6
  • 11
    • 0036719572 scopus 로고    scopus 로고
    • Are vitamin and mineral deficiencies a major cancer risk?
    • Ames,B.N. and Wakimoto,P. (2002) Are vitamin and mineral deficiencies a major cancer risk? Nat. Rev. Cancer, 2, 694-704.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 694-704
    • Ames, B.N.1    Wakimoto, P.2
  • 12
    • 0036195556 scopus 로고    scopus 로고
    • Effects of oral administration of N-acetyl-L-cysteine: A multi-biomarker study in smokers
    • Van Schooten,F.J., Besarati Nia,A., De Flora,S. et al. (2002) Effects of oral administration of N-acetyl-L-cysteine: A multi-biomarker study in smokers. Cancer Epidemiol. Biomarkers Prev., 11, 167-175.
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 167-175
    • Van Schooten, F.J.1    Besarati Nia, A.2    De Flora, S.3
  • 13
    • 0030762365 scopus 로고    scopus 로고
    • Cytogenetic effect of chronic low-dose, low-dose-rate gamma-radiation in residents of irradiated buildings
    • Chang,W.P., Hwang,B.F., Wang,D. and Wang,J.D. (1997) Cytogenetic effect of chronic low-dose, low-dose-rate gamma-radiation in residents of irradiated buildings. Lancet, 350, 330-333.
    • (1997) Lancet , vol.350 , pp. 330-333
    • Chang, W.P.1    Hwang, B.F.2    Wang, D.3    Wang, J.D.4
  • 14
    • 0038410184 scopus 로고    scopus 로고
    • Differential effectiveness of solar UVB subcomponents in causing cell death, oncogenic transformation and micronucleus induction in human hybrid cells
    • Bettega,D., Calzolari,P., Doneda,L., Belloni,F., Tallone,L. and Redpath,J.L. (2003) Differential effectiveness of solar UVB subcomponents in causing cell death, oncogenic transformation and micronucleus induction in human hybrid cells. Int. J. Radiat. Biol., 79, 211-216.
    • (2003) Int. J. Radiat. Biol. , vol.79 , pp. 211-216
    • Bettega, D.1    Calzolari, P.2    Doneda, L.3    Belloni, F.4    Tallone, L.5    Redpath, J.L.6
  • 15
    • 0028242630 scopus 로고
    • Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic Study Group on the Health Effects of Chromosome Damage
    • Hagmar,L., Brogger,A., Hansteen,I-L. et al. (1994) Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic Study Group on the Health Effects of Chromosome Damage. Cancer Res., 54, 2919-2922.
    • (1994) Cancer Res. , vol.54 , pp. 2919-2922
    • Hagmar, L.1    Brogger, A.2    Hansteen, I.-L.3
  • 16
    • 0032530829 scopus 로고    scopus 로고
    • Chromosomal aberrations in lymphocytes predict human cancer - A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)
    • Hagmar,L., Bonassi,S., Strömberg,U., Brøgger,A., Knudsen,L., Norppa,H. and Reuterwall,C. (1998) Chromosomal aberrations in lymphocytes predict human cancer - a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res., 58, 4117-4121.
    • (1998) Cancer Res. , vol.58 , pp. 4117-4121
    • Hagmar, L.1    Bonassi, S.2    Strömberg, U.3    Brøgger, A.4    Knudsen, L.5    Norppa, H.6    Reuterwall, C.7
  • 17
    • 0034653699 scopus 로고    scopus 로고
    • Chromosomal aberrations in lymphocytes predict human cancer independently from exposure to carcinogens
    • Bonassi,S., Hagmar,L., Strömberg,U. et al. (2000) Chromosomal aberrations in lymphocytes predict human cancer independently from exposure to carcinogens. Cancer Res., 60, 1619-1625.
    • (2000) Cancer Res. , vol.60 , pp. 1619-1625
    • Bonassi, S.1    Hagmar, L.2    Strömberg, U.3
  • 18
    • 1542720377 scopus 로고    scopus 로고
    • Impact of types of lymphocyte chromosomal aberrations on human cancer risk: Results from Nordic and Italian cohorts
    • Hagmar,L., Stromberg,U., Bonassi,S., Hansteen,I-L., Knudsen,L.E., Lindholm,C. and Norppa,H. (2004) Impact of types of lymphocyte chromosomal aberrations on human cancer risk: Results from Nordic and Italian cohorts. Cancer Res., 64, 2258-2263.
    • (2004) Cancer Res. , vol.64 , pp. 2258-2263
    • Hagmar, L.1    Stromberg, U.2    Bonassi, S.3    Hansteen, I.-L.4    Knudsen, L.E.5    Lindholm, C.6    Norppa, H.7
  • 20
    • 0021987630 scopus 로고
    • Measurement of micronuclei in human lymphocytes
    • Fenech,M. and Morley,A.A. (1985) Measurement of micronuclei in human lymphocytes. Mutat. Res., 147, 29-36.
    • (1985) Mutat. Res. , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 21
    • 0021325772 scopus 로고
    • Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man
    • Högstedt,B. (1984) Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man. Mutat. Res., 130, 63-72.
    • (1984) Mutat. Res. , vol.130 , pp. 63-72
    • Högstedt, B.1
  • 22
    • 0029044019 scopus 로고
    • Incorporating biomarkers into cancer epidemiology: A matrix of biomarker and study design categories
    • Rothman,N., Stewart,W.F. and Schulte,P.A. (1995) Incorporating biomarkers into cancer epidemiology: A matrix of biomarker and study design categories. Cancer Epidemiol. Biomarkers Prev., 4, 301-311.
    • (1995) Cancer Epidemiol. Biomarkers Prev. , vol.4 , pp. 301-311
    • Rothman, N.1    Stewart, W.F.2    Schulte, P.A.3
  • 25
    • 0038223465 scopus 로고    scopus 로고
    • StataCorp. STata Corporation, College Station, TX
    • StataCorp. (2001) Stata Statistical Software: Release 7.0. STata Corporation, College Station, TX.
    • (2001) Stata Statistical Software: Release 7.0
  • 26
    • 1842862771 scopus 로고    scopus 로고
    • Cytogenetic biomarkers
    • In: Buffler,P., Rice,J., Baan,R., Bird,M. and Boffetta,P., (eds) IARC Sci. Publ. IARC, Lyon
    • Norppa,H. (2004) Cytogenetic biomarkers. In: Buffler,P., Rice,J., Baan,R., Bird,M. and Boffetta,P., (eds) Mechanisms of Carcinogenesis: Contributions of Molecular Epidemiology. IARC Sci. Publ. Vol. 157, IARC, Lyon, pp. 179-205.
    • (2004) Mechanisms of Carcinogenesis: Contributions of Molecular Epidemiology , vol.157 , pp. 179-205
    • Norppa, H.1
  • 28
    • 0034978564 scopus 로고    scopus 로고
    • Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
    • Rudolph,K.L., Millard,M., Bosenberg,M.W. and DePinho,R.A. (2001) Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat. Genet., 28, 155-159.
    • (2001) Nat. Genet. , vol.28 , pp. 155-159
    • Rudolph, K.L.1    Millard, M.2    Bosenberg, M.W.3    DePinho, R.A.4
  • 29
    • 34047144919 scopus 로고    scopus 로고
    • Chromosomal aberrations and cancer risk: Results of a cohort study from Central Europe
    • (in press)
    • Boffetta,P., van der Hel,O., Norppa,H. et al. (2006) Chromosomal aberrations and cancer risk: Results of a cohort study from Central Europe. Am. J. Epidemiol., (in press).
    • (2006) Am. J. Epidemiol.
    • Boffetta, P.1    van der Hel, O.2    Norppa, H.3
  • 30
    • 33749631613 scopus 로고    scopus 로고
    • On the difference of micronucleus frequencies in peripheral blood lymphocytes between breast cancer patients and controls
    • Aug 22 [Epub ahead of print]
    • Varga,D., Hoegel,J., Maier,C. et al. (2006) On the difference of micronucleus frequencies in peripheral blood lymphocytes between breast cancer patients and controls. Mutagenesis, Aug 22 [Epub ahead of print].
    • (2006) Mutagenesis
    • Varga, D.1    Hoegel, J.2    Maier, C.3
  • 31
    • 3042591660 scopus 로고    scopus 로고
    • Folate deficiency induces aneuploidy in human lymphocytes in vitro - Evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21
    • Wang,X., Thomas,P., Xue,J. and Fenech,M. (2004) Folate deficiency induces aneuploidy in human lymphocytes in vitro - evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21. Mutat. Res., 551, 167-180.
    • (2004) Mutat. Res. , vol.551 , pp. 167-180
    • Wang, X.1    Thomas, P.2    Xue, J.3    Fenech, M.4
  • 32
    • 0034092837 scopus 로고    scopus 로고
    • Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase
    • Tanaka,T. and Shimizu,N. (2000) Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase. J. Cell. Sci., 113, 697-707.
    • (2000) J. Cell. Sci. , vol.113 , pp. 697-707
    • Tanaka, T.1    Shimizu, N.2
  • 33
    • 19544386112 scopus 로고    scopus 로고
    • Influence of caspase activity on micronuclei detection: A possible role for caspase-3 in micronucleation
    • Decordier,I., Cundari,E. and Kirsch-Volders,M. (2005) Influence of caspase activity on micronuclei detection: A possible role for caspase-3 in micronucleation. Mutagenesis, 20, 173-179.
    • (2005) Mutagenesis , vol.20 , pp. 173-179
    • Decordier, I.1    Cundari, E.2    Kirsch-Volders, M.3
  • 34
    • 0036020643 scopus 로고    scopus 로고
    • Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules
    • Decordier,I., Dillen,L., Cundari,E. and Kirsch-Volders,M. (2002) Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. Mutagenesis, 17, 337-344.
    • (2002) Mutagenesis , vol.17 , pp. 337-344
    • Decordier, I.1    Dillen, L.2    Cundari, E.3    Kirsch-Volders, M.4
  • 35
    • 0037172827 scopus 로고    scopus 로고
    • Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients
    • Migliore,L., Petrozzi,L., Lucetti,C. et al. (2002) Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients. Neurology, 58, 1809-1815.
    • (2002) Neurology , vol.58 , pp. 1809-1815
    • Migliore, L.1    Petrozzi, L.2    Lucetti, C.3
  • 36
    • 10944236160 scopus 로고    scopus 로고
    • Connecting mitotic instability and chromosome aberrations in cancer - Can telomeres bridge the gap?
    • Gisselsson,D. and Hoglund,M. (2005) Connecting mitotic instability and chromosome aberrations in cancer - can telomeres bridge the gap? Semin. Cancer Biol., 15, 13-23.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 13-23
    • Gisselsson, D.1    Hoglund, M.2
  • 37
    • 0141869980 scopus 로고    scopus 로고
    • Report from the in vitro micronucleus assay working group
    • Kirsch-Volders,M., Sofuni,T., Aardema,M. et al. (2003) Report from the in vitro micronucleus assay working group. Mutat. Res., 540, 153-163.
    • (2003) Mutat. Res. , vol.540 , pp. 153-163
    • Kirsch-Volders, M.1    Sofuni, T.2    Aardema, M.3
  • 38
    • 1842535882 scopus 로고    scopus 로고
    • Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
    • Mitelman,F.., Johansson,B. and Mertens,F. (2004) Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat. Genet., 36, 331-334.
    • (2004) Nat. Genet. , vol.36 , pp. 331-334
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 39
    • 25844475838 scopus 로고    scopus 로고
    • On the road to cancer: Aneuploidy and the mitotic checkpoint
    • Kops,G.J., Weaver,B.A. and Cleveland,D.W. (2005) On the road to cancer: aneuploidy and the mitotic checkpoint. Nat. Rev. Cancer, 10, 773-785.
    • (2005) Nat. Rev. Cancer , vol.10 , pp. 773-785
    • Kops, G.J.1    Weaver, B.A.2    Cleveland, D.W.3
  • 44
    • 24044508252 scopus 로고    scopus 로고
    • The Genome health clinic and genome health nutrigenomics concepts: Diagnosis and nutritional treatment of genome and epigenome damage on an individual basis
    • Fenech,M. (2005) The Genome health clinic and genome health nutrigenomics concepts: Diagnosis and nutritional treatment of genome and epigenome damage on an individual basis. Mutagenesis, 20, 255-269.
    • (2005) Mutagenesis , vol.20 , pp. 255-269
    • Fenech, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.