-
1
-
-
0032785259
-
The HUman MicroNucleus project - An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
-
Fenech,M., Holland,N., Chang,W.P., Zeiger,E. and Bonassi,S. (1999) The HUman MicroNucleus project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat. Res., 428, 271-283.
-
(1999)
Mutat. Res.
, vol.428
, pp. 271-283
-
-
Fenech, M.1
Holland, N.2
Chang, W.P.3
Zeiger, E.4
Bonassi, S.5
-
2
-
-
0346726185
-
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes
-
Kimura,M., Umegaki,K., Higuchi,M., Thomas,P. and Fenech,M. (2004) Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes. J. Nutr., 134, 48-56.
-
(2004)
J. Nutr.
, vol.134
, pp. 48-56
-
-
Kimura, M.1
Umegaki, K.2
Higuchi, M.3
Thomas, P.4
Fenech, M.5
-
3
-
-
17044379064
-
Human population studies with cytogenetic biomarkers: Review of the literature and future prospectives
-
Bonassi,S., Ugolini,D., Kirsch-Volders,M., Strömberg,U., Vermeulen,R. and Tucker,J.D. (2005) Human population studies with cytogenetic biomarkers: Review of the literature and future prospectives. Environ. Mol. Mutagenesis, 54, 258-270.
-
(2005)
Environ. Mol. Mutagenesis
, vol.54
, pp. 258-270
-
-
Bonassi, S.1
Ugolini, D.2
Kirsch-Volders, M.3
Strömberg, U.4
Vermeulen, R.5
Tucker, J.D.6
-
4
-
-
0034066102
-
Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
-
Umegaki,K. and Fenech,M. (2000) Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis, 15, 261-269.
-
(2000)
Mutagenesis
, vol.15
, pp. 261-269
-
-
Umegaki, K.1
Fenech, M.2
-
5
-
-
1542377277
-
Inactivation of hCDC4 can cause chromosomal instability
-
Rajagopalan,H., Jallepalli,P.V., Rago,C., Velculescu,V.E., Kinzler,K.W., Vogelstein,B. and Lengauer,C. (2004) Inactivation of hCDC4 can cause chromosomal instability. Nature, 428, 77-81.
-
(2004)
Nature
, vol.428
, pp. 77-81
-
-
Rajagopalan, H.1
Jallepalli, P.V.2
Rago, C.3
Velculescu, V.E.4
Kinzler, K.W.5
Vogelstein, B.6
Lengauer, C.7
-
6
-
-
0025067982
-
Dietary factors affecting spontaneous chromosomal damage in man
-
MacGregor,J.T. (1990) Dietary factors affecting spontaneous chromosomal damage in man. Prog. Clin. Biol. Res., 347, 139-153.
-
(1990)
Prog. Clin. Biol. Res.
, vol.347
, pp. 139-153
-
-
MacGregor, J.T.1
-
7
-
-
0034936018
-
MTHFR C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary lymphocyte DNA in vitro
-
(Accelerated Paper)
-
Crott,J.W., Mashiyama,S.T., Ames,B.N. and Fenech,M. (2001) MTHFR C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary lymphocyte DNA in vitro. (Accelerated Paper). Carcinogenesis, 22, 1019-1025.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1019-1025
-
-
Crott, J.W.1
Mashiyama, S.T.2
Ames, B.N.3
Fenech, M.4
-
8
-
-
19844378446
-
Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, b-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability - Results from a dietary intake and micronucleus index survey in South Australia
-
Fenech,M., Baghurst,P., Luderer,W., Turner,J., Record,S., Ceppi,M. and Bonassi,S. (2005) Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, b-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability - results from a dietary intake and micronucleus index survey in South Australia. Carcinogenesis, 26, 991-999.
-
(2005)
Carcinogenesis
, vol.26
, pp. 991-999
-
-
Fenech, M.1
Baghurst, P.2
Luderer, W.3
Turner, J.4
Record, S.5
Ceppi, M.6
Bonassi, S.7
-
9
-
-
0037112246
-
Chromosomal biomarkers of genomic instability relevant to cancer
-
Fenech,M. (2002) Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov. Today, 22, 1128-1137.
-
(2002)
Drug Discov. Today
, vol.22
, pp. 1128-1137
-
-
Fenech, M.1
-
10
-
-
0037427878
-
HUMN Project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
-
Fenech,M., Chang,W.P., Kirsch-Volders,M., Holland,N., Bonassi,S. and Zeiger,E. (2003) HUMN Project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res., 534, 65-75.
-
(2003)
Mutat. Res.
, vol.534
, pp. 65-75
-
-
Fenech, M.1
Chang, W.P.2
Kirsch-Volders, M.3
Holland, N.4
Bonassi, S.5
Zeiger, E.6
-
11
-
-
0036719572
-
Are vitamin and mineral deficiencies a major cancer risk?
-
Ames,B.N. and Wakimoto,P. (2002) Are vitamin and mineral deficiencies a major cancer risk? Nat. Rev. Cancer, 2, 694-704.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 694-704
-
-
Ames, B.N.1
Wakimoto, P.2
-
12
-
-
0036195556
-
Effects of oral administration of N-acetyl-L-cysteine: A multi-biomarker study in smokers
-
Van Schooten,F.J., Besarati Nia,A., De Flora,S. et al. (2002) Effects of oral administration of N-acetyl-L-cysteine: A multi-biomarker study in smokers. Cancer Epidemiol. Biomarkers Prev., 11, 167-175.
-
(2002)
Cancer Epidemiol. Biomarkers Prev.
, vol.11
, pp. 167-175
-
-
Van Schooten, F.J.1
Besarati Nia, A.2
De Flora, S.3
-
13
-
-
0030762365
-
Cytogenetic effect of chronic low-dose, low-dose-rate gamma-radiation in residents of irradiated buildings
-
Chang,W.P., Hwang,B.F., Wang,D. and Wang,J.D. (1997) Cytogenetic effect of chronic low-dose, low-dose-rate gamma-radiation in residents of irradiated buildings. Lancet, 350, 330-333.
-
(1997)
Lancet
, vol.350
, pp. 330-333
-
-
Chang, W.P.1
Hwang, B.F.2
Wang, D.3
Wang, J.D.4
-
14
-
-
0038410184
-
Differential effectiveness of solar UVB subcomponents in causing cell death, oncogenic transformation and micronucleus induction in human hybrid cells
-
Bettega,D., Calzolari,P., Doneda,L., Belloni,F., Tallone,L. and Redpath,J.L. (2003) Differential effectiveness of solar UVB subcomponents in causing cell death, oncogenic transformation and micronucleus induction in human hybrid cells. Int. J. Radiat. Biol., 79, 211-216.
-
(2003)
Int. J. Radiat. Biol.
, vol.79
, pp. 211-216
-
-
Bettega, D.1
Calzolari, P.2
Doneda, L.3
Belloni, F.4
Tallone, L.5
Redpath, J.L.6
-
15
-
-
0028242630
-
Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic Study Group on the Health Effects of Chromosome Damage
-
Hagmar,L., Brogger,A., Hansteen,I-L. et al. (1994) Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic Study Group on the Health Effects of Chromosome Damage. Cancer Res., 54, 2919-2922.
-
(1994)
Cancer Res.
, vol.54
, pp. 2919-2922
-
-
Hagmar, L.1
Brogger, A.2
Hansteen, I.-L.3
-
16
-
-
0032530829
-
Chromosomal aberrations in lymphocytes predict human cancer - A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)
-
Hagmar,L., Bonassi,S., Strömberg,U., Brøgger,A., Knudsen,L., Norppa,H. and Reuterwall,C. (1998) Chromosomal aberrations in lymphocytes predict human cancer - a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res., 58, 4117-4121.
-
(1998)
Cancer Res.
, vol.58
, pp. 4117-4121
-
-
Hagmar, L.1
Bonassi, S.2
Strömberg, U.3
Brøgger, A.4
Knudsen, L.5
Norppa, H.6
Reuterwall, C.7
-
17
-
-
0034653699
-
Chromosomal aberrations in lymphocytes predict human cancer independently from exposure to carcinogens
-
Bonassi,S., Hagmar,L., Strömberg,U. et al. (2000) Chromosomal aberrations in lymphocytes predict human cancer independently from exposure to carcinogens. Cancer Res., 60, 1619-1625.
-
(2000)
Cancer Res.
, vol.60
, pp. 1619-1625
-
-
Bonassi, S.1
Hagmar, L.2
Strömberg, U.3
-
18
-
-
1542720377
-
Impact of types of lymphocyte chromosomal aberrations on human cancer risk: Results from Nordic and Italian cohorts
-
Hagmar,L., Stromberg,U., Bonassi,S., Hansteen,I-L., Knudsen,L.E., Lindholm,C. and Norppa,H. (2004) Impact of types of lymphocyte chromosomal aberrations on human cancer risk: Results from Nordic and Italian cohorts. Cancer Res., 64, 2258-2263.
-
(2004)
Cancer Res.
, vol.64
, pp. 2258-2263
-
-
Hagmar, L.1
Stromberg, U.2
Bonassi, S.3
Hansteen, I.-L.4
Knudsen, L.E.5
Lindholm, C.6
Norppa, H.7
-
19
-
-
19044387319
-
Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer
-
Rossner,P., Boffetta,P., Ceppi,M., Bonassi,S., Smerhovsky,Z., Landa,K., Juzova,D. and Sram,R.J. (2005) Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer. Environ. Health Perspect., 113, 517-520.
-
(2005)
Environ. Health Perspect.
, vol.113
, pp. 517-520
-
-
Rossner, P.1
Boffetta, P.2
Ceppi, M.3
Bonassi, S.4
Smerhovsky, Z.5
Landa, K.6
Juzova, D.7
Sram, R.J.8
-
20
-
-
0021987630
-
Measurement of micronuclei in human lymphocytes
-
Fenech,M. and Morley,A.A. (1985) Measurement of micronuclei in human lymphocytes. Mutat. Res., 147, 29-36.
-
(1985)
Mutat. Res.
, vol.147
, pp. 29-36
-
-
Fenech, M.1
Morley, A.A.2
-
21
-
-
0021325772
-
Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man
-
Högstedt,B. (1984) Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man. Mutat. Res., 130, 63-72.
-
(1984)
Mutat. Res.
, vol.130
, pp. 63-72
-
-
Högstedt, B.1
-
22
-
-
0029044019
-
Incorporating biomarkers into cancer epidemiology: A matrix of biomarker and study design categories
-
Rothman,N., Stewart,W.F. and Schulte,P.A. (1995) Incorporating biomarkers into cancer epidemiology: A matrix of biomarker and study design categories. Cancer Epidemiol. Biomarkers Prev., 4, 301-311.
-
(1995)
Cancer Epidemiol. Biomarkers Prev.
, vol.4
, pp. 301-311
-
-
Rothman, N.1
Stewart, W.F.2
Schulte, P.A.3
-
25
-
-
0038223465
-
-
StataCorp. STata Corporation, College Station, TX
-
StataCorp. (2001) Stata Statistical Software: Release 7.0. STata Corporation, College Station, TX.
-
(2001)
Stata Statistical Software: Release 7.0
-
-
-
26
-
-
1842862771
-
Cytogenetic biomarkers
-
In: Buffler,P., Rice,J., Baan,R., Bird,M. and Boffetta,P., (eds) IARC Sci. Publ. IARC, Lyon
-
Norppa,H. (2004) Cytogenetic biomarkers. In: Buffler,P., Rice,J., Baan,R., Bird,M. and Boffetta,P., (eds) Mechanisms of Carcinogenesis: Contributions of Molecular Epidemiology. IARC Sci. Publ. Vol. 157, IARC, Lyon, pp. 179-205.
-
(2004)
Mechanisms of Carcinogenesis: Contributions of Molecular Epidemiology
, vol.157
, pp. 179-205
-
-
Norppa, H.1
-
27
-
-
17244367777
-
Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity
-
Stewenius,Y., Gorunova,L., Jonson,T., Larsson,N., Hoglund,M., Mandahl,N., Mertens,F., Mitelman,F. and Gisselsson,D. (2005) Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity. Proc. Natl Acad. Sci. USA, 102, 5541-5546.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 5541-5546
-
-
Stewenius, Y.1
Gorunova, L.2
Jonson, T.3
Larsson, N.4
Hoglund, M.5
Mandahl, N.6
Mertens, F.7
Mitelman, F.8
Gisselsson, D.9
-
28
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
Rudolph,K.L., Millard,M., Bosenberg,M.W. and DePinho,R.A. (2001) Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat. Genet., 28, 155-159.
-
(2001)
Nat. Genet.
, vol.28
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
DePinho, R.A.4
-
29
-
-
34047144919
-
Chromosomal aberrations and cancer risk: Results of a cohort study from Central Europe
-
(in press)
-
Boffetta,P., van der Hel,O., Norppa,H. et al. (2006) Chromosomal aberrations and cancer risk: Results of a cohort study from Central Europe. Am. J. Epidemiol., (in press).
-
(2006)
Am. J. Epidemiol.
-
-
Boffetta, P.1
van der Hel, O.2
Norppa, H.3
-
30
-
-
33749631613
-
On the difference of micronucleus frequencies in peripheral blood lymphocytes between breast cancer patients and controls
-
Aug 22 [Epub ahead of print]
-
Varga,D., Hoegel,J., Maier,C. et al. (2006) On the difference of micronucleus frequencies in peripheral blood lymphocytes between breast cancer patients and controls. Mutagenesis, Aug 22 [Epub ahead of print].
-
(2006)
Mutagenesis
-
-
Varga, D.1
Hoegel, J.2
Maier, C.3
-
31
-
-
3042591660
-
Folate deficiency induces aneuploidy in human lymphocytes in vitro - Evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21
-
Wang,X., Thomas,P., Xue,J. and Fenech,M. (2004) Folate deficiency induces aneuploidy in human lymphocytes in vitro - evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21. Mutat. Res., 551, 167-180.
-
(2004)
Mutat. Res.
, vol.551
, pp. 167-180
-
-
Wang, X.1
Thomas, P.2
Xue, J.3
Fenech, M.4
-
32
-
-
0034092837
-
Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase
-
Tanaka,T. and Shimizu,N. (2000) Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase. J. Cell. Sci., 113, 697-707.
-
(2000)
J. Cell. Sci.
, vol.113
, pp. 697-707
-
-
Tanaka, T.1
Shimizu, N.2
-
33
-
-
19544386112
-
Influence of caspase activity on micronuclei detection: A possible role for caspase-3 in micronucleation
-
Decordier,I., Cundari,E. and Kirsch-Volders,M. (2005) Influence of caspase activity on micronuclei detection: A possible role for caspase-3 in micronucleation. Mutagenesis, 20, 173-179.
-
(2005)
Mutagenesis
, vol.20
, pp. 173-179
-
-
Decordier, I.1
Cundari, E.2
Kirsch-Volders, M.3
-
34
-
-
0036020643
-
Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules
-
Decordier,I., Dillen,L., Cundari,E. and Kirsch-Volders,M. (2002) Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. Mutagenesis, 17, 337-344.
-
(2002)
Mutagenesis
, vol.17
, pp. 337-344
-
-
Decordier, I.1
Dillen, L.2
Cundari, E.3
Kirsch-Volders, M.4
-
35
-
-
0037172827
-
Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients
-
Migliore,L., Petrozzi,L., Lucetti,C. et al. (2002) Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients. Neurology, 58, 1809-1815.
-
(2002)
Neurology
, vol.58
, pp. 1809-1815
-
-
Migliore, L.1
Petrozzi, L.2
Lucetti, C.3
-
36
-
-
10944236160
-
Connecting mitotic instability and chromosome aberrations in cancer - Can telomeres bridge the gap?
-
Gisselsson,D. and Hoglund,M. (2005) Connecting mitotic instability and chromosome aberrations in cancer - can telomeres bridge the gap? Semin. Cancer Biol., 15, 13-23.
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 13-23
-
-
Gisselsson, D.1
Hoglund, M.2
-
37
-
-
0141869980
-
Report from the in vitro micronucleus assay working group
-
Kirsch-Volders,M., Sofuni,T., Aardema,M. et al. (2003) Report from the in vitro micronucleus assay working group. Mutat. Res., 540, 153-163.
-
(2003)
Mutat. Res.
, vol.540
, pp. 153-163
-
-
Kirsch-Volders, M.1
Sofuni, T.2
Aardema, M.3
-
38
-
-
1842535882
-
Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
-
Mitelman,F.., Johansson,B. and Mertens,F. (2004) Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat. Genet., 36, 331-334.
-
(2004)
Nat. Genet.
, vol.36
, pp. 331-334
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
39
-
-
25844475838
-
On the road to cancer: Aneuploidy and the mitotic checkpoint
-
Kops,G.J., Weaver,B.A. and Cleveland,D.W. (2005) On the road to cancer: aneuploidy and the mitotic checkpoint. Nat. Rev. Cancer, 10, 773-785.
-
(2005)
Nat. Rev. Cancer
, vol.10
, pp. 773-785
-
-
Kops, G.J.1
Weaver, B.A.2
Cleveland, D.W.3
-
40
-
-
0037133211
-
Centrosome amplification drives chromosomal instability in breast tumor development
-
Lingle,W.L., Barrett,S.L., Negron,V.C., D'Assoro,A.B., Boeneman,K., Liu,W., Whitehead,C.M., Reynolds,C. and Salisbury,J.L. (2002) Centrosome amplification drives chromosomal instability in breast tumor development. Proc. Natl Acad. Sci. USA, 99, 1978-1983.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 1978-1983
-
-
Lingle, W.L.1
Barrett, S.L.2
Negron, V.C.3
D'Assoro, A.B.4
Boeneman, K.5
Liu, W.6
Whitehead, C.M.7
Reynolds, C.8
Salisbury, J.L.9
-
41
-
-
33645074134
-
Chromosomal instability in MYH- and APC-mutant adenomatous polyps
-
Cardoso,J., Molenaar,L., de Menezes,R.X., van Leerdam,M., Rosenberg,C., Moslein,G., Sampson,J., Morreau,H., Boer,J.M. and Fodde,R. (2006) Chromosomal instability in MYH- and APC-mutant adenomatous polyps. Cancer Res., 66, 2514-2519.
-
(2006)
Cancer Res.
, vol.66
, pp. 2514-2519
-
-
Cardoso, J.1
Molenaar, L.2
de Menezes, R.X.3
van Leerdam, M.4
Rosenberg, C.5
Moslein, G.6
Sampson, J.7
Morreau, H.8
Boer, J.M.9
Fodde, R.10
-
42
-
-
0037624671
-
Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett's oesophagus
-
Doak,S.H., Jenkins,G.J.S., Parry,E.M., D'Souza,F.R., Griffiths,A.P., Toffazal,N., Shah,V., Baxter,J.N. and Parry,J.M. (2003) Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett's oesophagus. Gut, 52, 623-628.
-
(2003)
Gut
, vol.52
, pp. 623-628
-
-
Doak, S.H.1
Jenkins, G.J.S.2
Parry, E.M.3
D'Souza, F.R.4
Griffiths, A.P.5
Toffazal, N.6
Shah, V.7
Baxter, J.N.8
Parry, J.M.9
-
43
-
-
31644436369
-
Tetraploidy and chromosomal instability are early events during cervical carcinogenesis
-
Olaharski,A., Sotelo,R., Solorza-Luna,G., Gonsebatt,M.E., Guzman,P., Mohar,A. and Eastmond,D.A. (2006) Tetraploidy and chromosomal instability are early events during cervical carcinogenesis. Carcinogenesis, 27, 337-343.
-
(2006)
Carcinogenesis
, vol.27
, pp. 337-343
-
-
Olaharski, A.1
Sotelo, R.2
Solorza-Luna, G.3
Gonsebatt, M.E.4
Guzman, P.5
Mohar, A.6
Eastmond, D.A.7
-
44
-
-
24044508252
-
The Genome health clinic and genome health nutrigenomics concepts: Diagnosis and nutritional treatment of genome and epigenome damage on an individual basis
-
Fenech,M. (2005) The Genome health clinic and genome health nutrigenomics concepts: Diagnosis and nutritional treatment of genome and epigenome damage on an individual basis. Mutagenesis, 20, 255-269.
-
(2005)
Mutagenesis
, vol.20
, pp. 255-269
-
-
Fenech, M.1
|