Differential effects of ethanol on serum GABAergic 3α,5α/ 3α,5β neuroactive steroids in mice, rats, cynomolgus monkeys, and humans

Alcoholism: Clinical and Experimental Research

Volumn 34, Issue 3, 2010, Pages 432-442

  Porcu, Patrizia ^a   O'Buckley, Todd K ^a   Alward, Sarah E ^a   Song, Soomin C ^a   Grant, Kathleen A ^b   De Wit, Harriet ^c   Leslie Morrow, A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

C57BL 6J and DBA 2J Mice; Ethanol; GABAergic Neuroactive Steroids; Humans; Nonhuman Primates

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA,5ALPHA 3,21 DIHYDROXYPREGNAN 20 ONE; 3ALPHA,5ALPHA ANDROSTANDIOL; 3ALPHA,5ALPHA ANDROSTERONE; 3ALPHA,5BETA 3,21 DIHYDROXYPREGNAN 20 ONE; 3ALPHA,5BETA ANDROSTANDIOL; 3ALPHA,5BETA ANDROSTERONE; ALCOHOL; ANDROSTANEDIOL; ANDROSTERONE DERIVATIVE; ELTANOLONE; NEUROSTEROID; PREGNENOLONE; UNCLASSIFIED DRUG;

ADULT; ALCOHOL CONSUMPTION; ANDROGEN BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID BLOOD LEVEL; GABAERGIC SYSTEM; GESTAGEN BLOOD LEVEL; HORMONAL REGULATION; HUMAN; HUMAN EXPERIMENT; MACACA; MALE; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; STEROID ANALYSIS; STEROID BLOOD LEVEL;

ADULT; ANDROSTANE-3,17-DIOL; ANDROSTERONE; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DESOXYCORTICOSTERONE; ETHANOL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MACACA FASCICULARIS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; PREGNANOLONE; PREGNENOLONE; RATS; RATS, SPRAGUE-DAWLEY; YOUNG ADULT;

MACACA FASCICULARIS; MUS; PRIMATES; RATTUS;

EID: 77749295132     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.01123.x     Document Type: Article

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