Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis

Journal of Neurochemistry

Volumn 112, Issue 3, 2010, Pages 784-796

  Boyd, Kevin N ^b   Kumar, Sandeep ^b   O'Buckley, Todd K ^b   Porcu, Patrizia ^b   Morrow, A Leslie ^a,b  

^a 3027 Thurston Bowles Bldg CB#7178 ^*  (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

ACTH; Adrenal; Brain; Ethanol; GABA; Neuroactive steroid

Indexed keywords

(3ALPHA,5ALPHA) 3 HYDROXYPREGNAN 20 ONE; (3ALPHA,5ALPHA) 3,21 DIHYDROXYPREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; CORTICOTROPIN; PROGESTERONE; STEROID; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ADRENAL GLAND; ALCOHOL ABUSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN; BRAIN LEVEL; CONTROLLED STUDY; CORTICOTROPIN RELEASE; IMMUNOPRECIPITATION; MALE; NONHUMAN; PLASMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; STEROIDOGENESIS; WESTERN BLOTTING;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYCLOHEXIMIDE; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GABA AGENTS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HYPOPHYSECTOMY; IMIDAZOLES; IMMUNOGLOBULIN G; IMMUNOPRECIPITATION; ISOQUINOLINES; MALE; MELPHALAN; PHOSPHOPROTEINS; PREGNANOLONE; PREGNENOLONE; PROTEIN SYNTHESIS INHIBITORS; PYRIDINES; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; STEROIDS;

RATTUS;

EID: 73949085493     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06509.x     Document Type: Article

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