Allopregnanolone does not influence ethanol-induced conditioned place preference in DBA/2J mice

Psychopharmacology

Volumn 176, Issue 1, 2004, Pages 50-56

  Gabriel, Kara I ^a   Cunningham, Christopher L ^a,b   Finn, Deborah A ^a,b,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Allopregnanolone; DBA 2J; Ethanol; Locomotor activity; Place conditioning

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ALCOHOL; FINASTERIDE; SODIUM CHLORIDE; STEROID 5ALPHA REDUCTASE INHIBITOR;

ARTICLE; CONDITIONING; DOSE RESPONSE; DRUG EFFECT; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIMULATION; STIMULATION; STIMULUS RESPONSE;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN CHEMISTRY; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ETHANOL; FINASTERIDE; INJECTIONS, INTRAPERITONEAL; LOCOMOTION; MALE; MICE; MICE, INBRED DBA; PREGNANOLONE; PSYCHOPHARMACOLOGY; SPECIES SPECIFICITY; TIME FACTORS;

EID: 3142585854     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-1862-2     Document Type: Article

References (34)

1. Bardo MT, Bevins RA (2000) Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology 153:31-43
2. Beauchamp MH, Ormerod BK, Jhamandas K, Boegman RJ, Beninger RJ (2000) Neurosteroids and reward: allopregnanolone produces a conditioned place aversion in rats. Pharmacol Biochem Behav 67:29-35
3. Bowen CA, Purdy RH, Grant ICA (1999) Ethanol-like discriminative stimulus effects of endogenous neuroactive steroids: effect of ethanol training dose and dosing procedure. J Pharmacol Exp Ther 289:405-411
4. Broadbent J, Cunningham CL (1996) Pavlovian conditioning of morphine hyperthermia: assessment of interstimulus interval and CS-US overlap. Psychopharmacology 126:156-164
5. Chester JA, Cunningham CL (1998) Modulation of corticosterone does not affect the acquisition or expression of ethanol-induced conditioned place preference in DBA/2J mice. Pharmacol Biochem Behav 59:67-75
6. A receptors modulate ethanol-induced conditioned place preference and taste aversion in mice. Psychopharmacology 144:363-372
7. A receptor modulation of the rewarding and aversive effects of ethanol. Alcohol 26:131-143
8. Cunningham CL (1993) Pavlovian drug conditioning. In: van Haaren F (ed) Methods in behavioral pharmacology (techniques in the behavioral and neural sciences). Elsevier, New York, pp 349-381
9. Cunningham CL, Niehus DR, Malott DH, Prather LK (1992) Genetic differences in the rewarding and activating effects of morphine and ethanol. Psychopharmacology 107:385-393
10. Cunningham CL, Niehus JS, Noble D (1993) Species difference in sensitivity to ethanol's hedonic effects. Alcohol 10:97-102
11. Cunningham CL, Ferree NK, Howard MA (2003) Apparatus bias and place conditioning with ethanol in mice. Psychopharmacology 170:409-422
12. Devaud LL, Purdy RH, Morrow AL (1995) The neurosteroid, 3α-hydroxy-5α-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats. Alcohol Clin Exp Res 19:350-355
13. Dickinson SD (1996) Characterization of naloxone's effects on the expression of ethanol-induced conditioned place preference in mice. PhD dissertation in behavioral neuroscience. Oregon Health & Science University, Portland, Ore., p 189
14. Finn DA, Gee KW (1994) The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid. J Pharmacol Exp Ther 271:164-170
15. Finn DA, Phillips TJ, Okorn DM, Chester JA, Cunningham CL (1997a) Rewarding effect of the neuroactive steroid 3α-hydroxy-5α-pregnan- 20-one in mice. Pharmacol Biochem Behav 56:261-264
16. Finn DA, Roberts AJ, Lotrich F, Gallaher EJ (1997b) Genetic differences in behavioral sensitivity to a neuroactive steroid. J Pharmacol Exp Ther 280:820-828
17. Finn DA, Gallaher EJ, Crabbe JC (2000) Differential change in neuroactive steroid sensitivity during ethanol withdrawal. J Pharmacol Exp Ther 292:394-405
18. Finn DA, Sinnott RS, Ford MM, Long SL, Tanchuck MA, Phillips TJ (2004) Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice. Neuroscience 123:813-819
19. Fish EW, Faccidomo S, DeBold JF, Miczek KA (2001) Alcohol, allopregnanolone and aggression in mice. Psychopharmacology 153:473-483
20. Grant KA, Azarov A, Bowen CA, Mirkis S, Purdy RH (1996) Ethanol-like discriminative stimulus effects of the neurosteroid 3α-hydroxy-5α- pregnan-20-one in female Macaca fascicularis monkeys. Psychopharmacology 124:340-346
21. Janak PH, Redfern JE, Samson HH (1998) The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone. Alcohol Clin Exp Res 22:1106-1112
22. Janis GC, Devaud LL, Mitsuyama H, Morrow AL (1998) Effects of chronic ethanol consumption and withdrawal on the neuroactive steroid 3α-hydroxy-5α-pregnan-20-one in male and female rats. Alcohol Clin Exp Res 22:2055-2061
23. Morrow AL, Janis GC, VanDoren MJ, Matthews DB, Samson HH, Janak PH, Grant KA (1999) Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of ethanol action? Alcohol Clin Exp Res 23:1933-1940
24. Morrow AL, VanDoren MJ, Penland SN, Matthews DB (2001) The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence. Brain Res Brain Res Rev 37:98-109
25. Nie H, Janak PH (2003) Comparison of reinstatement of ethanol-and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats. Psychopharmacology 168:222-228
26. Palmer AA, Miller MN, McKinnon CS, Phillips TJ (2002) Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes. Behav Neurosci 116:126-137
27. Paul SM, Purdy RH (1992) Neuroactive steroids. Fed Am Soc Exp Biol J 6:2311-2322
28. Perry NM (1997) Benzodiazepine-GABA modulation of concurrent ethanol and sucrose reinforcement in the rat. Exp Clin Psychopharmacol 5:183-194
29. Rowlett JK, Winger G, Carter RB, Wood PL, Woods JH, Woolverton WL (1999) Reinforcing and discriminative stimulus effects of the neuroactive steroids pregnanolone and Co 8-7071 in rhesus monkeys. Psychopharmacology 145:205-212
30. Sinnott RS, Phillips TJ, Finn DA (2002) Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice. Psychopharmacology 162:438-447
31. Ticku MK (1991) Ethanol interactions at the gamma-aminobutyric acid receptor complex. Ann N Y Acad Sci 625:136-144
32. VanDoren MJ, Matthews DB, Janis GC, Grobin AC, Devaud LL, Morrow AL (2000) Neuroactive steroid 3α-hydroxy-5α-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol. J Neurosci 20:1982-1989
33. A receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol. Psychopharmacology 141:77-82
34. Wieland S, Belluzzi JD, Stein L, Lan NC (1995) Comparative behavioral characterization of the neuroactive steroids 3α-OH,5α-pregnan-20-one and 3α-OH,5β-pregnan-20-one in rodents. Psychopharmacology 188:65-71