Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice

Behavioural Brain Research

Volumn 179, Issue 2, 2007, Pages 265-272

  Ford, Matthew M ^b   Mark, Gregory P ^b   Nickel, Jeffrey D ^b   Phillips, Tamara J ^a,b   Finn, Deborah A ^a,b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Alcohol intake; Animal model; Drinking patterns; Lickometer; Locomotor activity; Neurosteroid; Operant; Reinforcement

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANNULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG SELF ADMINISTRATION; FLUID INTAKE; FOOD INTAKE; HORMONAL REGULATION; LATERAL BRAIN VENTRICLE; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SATIETY;

ALCOHOL DRINKING; ANALYSIS OF VARIANCE; ANIMALS; CONDITIONING, OPERANT; CONSUMMATORY BEHAVIOR; ETHANOL; GABA MODULATORS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PREGNANOLONE; RECEPTORS, GABA-A; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 33947626625     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2007.02.028     Document Type: Article

References (44)

1. Andréen L., Sundstrom-Poromaa I., Bixo M., Nyberg S., and Backstrom T. Allopregnanolone concentration and mood-a bimodal association in postmenopausal women treated with oral progesterone. Psychopharmacology 187 (2006) 209-221
2. A receptor. Nat Rev Neurosci 6 (2005) 565-575
3. Bowen C.A., Purdy R.H., and Grant K.A. An investigation of endogenous neuroactive steroid-induced modulation of ethanol's discriminative stimulus effects. Behav Pharmacol 10 (1999) 297-311
4. Cunningham C.L., Fidler T.L., and Hill K.G. Animal models of alcohol's motivational effects. Alcohol Res Health 24 (2000) 85-92
5. Czachowski C.L., Legg B.H., and Samson H.H. Effects of acamprosate on ethanol-seeking and self-administration in the rat. Alcohol Clin Exp Res 25 (2001) 344-350
6. Czachowski C.L., Santini L.A., Legg B.H., and Samson H.H. Separate measures of ethanol seeking and drinking in the rat: effects of remoxipride. Alcohol 28 (2002) 39-46
7. Czlonkowska A.I., Krzascik P., Sienkiewicz-Jarosz H., Siemiatkowski M., Szyndler J., Bidzinski A., et al. The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol. Pharmacol Biochem Behav 67 (2000) 345-353
8. Finn D.A., Ford M.M., Wiren K.M., Roselli C.E., and Crabbe J.C. The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches. Pharmacol Ther 101 (2004) 91-112
9. Finn D.A., Phillips T.J., Okorn D.M., Chester J.A., and Cunningham C.L. Rewarding effect of the neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in mice. Pharmacol Biochem Behav 56 (1997) 261-264
10. Finn D.A., Sinnott R.S., Ford M.M., Long S.L., Tanchuck M.A., and Phillips T.J. Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice. Neuroscience 123 (2004) 813-819
11. Fish E.W., Faccidomo S., DeBold J.F., and Miczek K.A. Alcohol, allopregnanolone and aggression in mice. Psychopharmacology 153 (2001) 473-483
12. Ford M.M., Eldridge J.C., and Samson H.H. Microanalysis of ethanol self-administration: estrous cycle phase-related changes in consumption patterns. Alcohol Clin Exp Res 26 (2002) 635-643
13. Ford M.M., Nickel J.D., and Finn D.A. Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?. Alcohol 37 (2005) 23-33
14. A receptors differentially modulate ethanol intake patterns in male C57BL/6J mice. Alcohol Clin Exp Res 29 (2005) 1630-1640
15. Gallaher E.J., Jones G.E., Belknap J.K., and Crabbe J.C. Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred mice. J Pharmacol Exp Ther 277 (1996) 604-612
16. Grant K.A. Strategies for understanding the pharmacological effects of ethanol with drug discrimination procedures. Pharmacol Biochem Behav 64 (1999) 261-267
17. Grant K.A., Azarov A., Bowen C.A., Mirkis S., and Purdy R.H. Ethanol-like discriminative stimulus effects of the neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in female Macaca fascicularis monkeys. Psychopharmacology 124 (1996) 340-346
18. A receptors in the acute and chronic effects of ethanol. Psychopharmacology 139 (1998) 2-19
19. Hodge C.W., Nannini M.A., Olive M.F., Kelley S.P., and Mehmert K.K. Allopregnanolone and pentobarbital infused into the nucleus accumbens substitute for the discriminative stimulus effects of ethanol. Alcohol Clin Exp Res 25 (2001) 1441-1447
20. Janak P.H., and Gill T.M. Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose. Alcohol 30 (2003) 1-7
21. Janak P.H., Redfern J.E., and Samson H.H. The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone. Alcohol Clin Exp Res 22 (1998) 1106-1112
22. A receptor. Mechanism of action and physiological significance. Prog Neurobiol 38 (1992) 379-395
23. Middaugh L.D., Lee A.M., and Bandy A.L. Ethanol reinforcement in non-deprived mice: effects of abstinence and naltrexone. Alcohol Clin Exp Res 24 (2000) 1172-1179
24. Motzo C., Porceddu M.L., Maira G., Flore G., Concas A., Dazzi L., et al. Inhibition of basal and stress-induced dopamine release in the cerebral cortex and nucleus accumbens of freely moving rats by the neurosteroid allopregnanolone. J Psychopharmacology 10 (1996) 266-272
25. National Research Council of the National Academies. Guide for the care and use of mammals in neuroscience and behavioral research (2003), National Academies Press, Washington, DC
26. Nie H., and Janak P.H. Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats. Psychopharmacology 168 (2003) 222-228
27. Palmer A.A., Miller M.N., McKinnon C.S., and Phillips T.J. Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes. Behav Neurosci 116 (2002) 126-137
28. A channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids. Pain 114 (2005) 429-443
29. Paxinos G., and Franklin K.B.J. The mouse brain in stereotaxic coordinates. 2nd ed. (2001), Academic Press, New York
30. Phillips T.J., Broadbent J., Burkhart-Kasch S., Henderson C., Wenger C.D., McMullin C., et al. Genetic correlational analyses of ethanol reward and aversion phenotypes in short-term selected mouse lines bred for ethanol drinking or ethanol-induced conditioned taste aversion. Behav Neurosci 119 (2005) 892-910
31. A and mitochondrial diazepam-binding inhibitor receptors on the effects of neurosteroids on food intake in mice. Psychopharmacology 137 (1998) 391-400
32. Rouge-Pont F., Mayo W., Marinelli M., Gingras M., Le Moal M., and Piazza PV. The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens. Eur J Neurosci 16 (2002) 169-173
33. Rowlett J.K., Winger G., Carter R.B., Wood P.L., Woods J.H., and Woolverton W.L. Reinforcing and discriminative stimulus effects of the neuroactive steroids pregnanolone and Co 8-7071 in rhesus monkeys. Psychopharmacology 145 (1999) 205-212
34. Rupprecht R., and Holsboer F. Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives. Trends Neurosci 22 (1999) 410-416
35. Samson H.H. Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. Alcohol Clin Exp Res 10 (1986) 436-442
36. Samson H.H., and Chappell A.M. Effects of raclopride in the core of the nucleus accumbens on ethanol seeking and consumption: the use of extinction trials to measure seeking. Alcohol Clin Exp Res 28 (2004) 544-549
37. Samson H.H., Czachowski C.L., and Slawecki C.J. A new assessment of the ability of oral ethanol to function as a reinforcing stimulus. Alcohol Clin Exp Res 24 (2000) 766-773
38. Samson H.H., Slawecki C.J., Sharpe A.L., and Chappell A. Appetitive and consummatory behaviors in the control of ethanol consumption: a measure of ethanol seeking behavior. Alcohol Clin Exp Res 22 (1998) 1783-1787
39. Sharpe A.L., and Samson H.H. Effect of naloxone on appetitive and consummatory phases of ethanol self-administration. Alcohol Clin Exp Res 25 (2001) 1006-1011
40. Sharpe A.L., and Samson H.H. Repeated nicotine injections decrease operant ethanol self-administration. Alcohol 28 (2002) 1-7
41. Sinnott R.S., Mark G.P., and Finn D.A. Reinforcing effects of the neurosteroid allopregnanolone in rats. Pharmacol Biochem Behav 72 (2002) 923-929
42. Sinnott R.S., Phillips T.J., and Finn D.A. Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice. Psychopharmacology 162 (2002) 438-447
43. Torres J.M., and Ortega E. Alcohol intoxication increases allopregnanolone levels in female adolescent humans. Neuropsychopharmacology 28 (2003) 1207-1209
44. Torres J.M., and Ortega E. Alcohol intoxication increases allopregnanolone levels in male adolescent humans. Psychopharmacology 172 (2004) 352-355