Transgenic mice dificient in the LAR prottein-tyrosine phosphatase exhibit profound defects in glucose homeostasis

Diabetes

Volumn 47, Issue 3, 1998, Pages 493-497

  Ren, Jian Ming ^b   Li, Pei Ming ^a   Zhang, Wei Ren ^a   Sweet, Laurel J ^b   Cline, Gary ^c   Shulman, Gerald I ^c   Livingston, James N ^b   Goldstein, Barry J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b BAYER CORPORATION   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE PHOSPHATASE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE INSERTION; GLUCONEOGENESIS; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TRANSGENIC MOUSE; ANIMAL; COHORT ANALYSIS; COMPARATIVE STUDY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; LIVER; METABOLISM; MOUSE; MOUSE MUTANT; PHENOTYPE; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; COHORT STUDIES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HOMEOSTASIS; LIVER; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; PHOSPHOPROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RECEPTOR, INSULIN;

EID: 0031594367     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.3.493     Document Type: Article

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