Whole body autoradiographic study on the distribution of 14C-D-serine administered intravenously to rats

Amino Acids

Volumn 15, Issue 4, 1998, Pages 351-361

  Imai, Kazuhiro ^a   Fukushima, T ^a   Santa, T ^a   Homma, H ^a   Huang, Y ^a   Shirao, M ^a   Miura, K ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b FUJIFILM CORPORATION   (Japan)

Author keywords

14C D serine; Accumulation; Amino acids; Kidney; Rat; Whole body autoradiography

Indexed keywords

CARBON 14; SERINE;

ANIMAL EXPERIMENT; ARTICLE; DIETARY INTAKE; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; KIDNEY NECROSIS; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RAT; WHOLE BODY AUTORADIOGRAPHY;

ANIMALS; AUTORADIOGRAPHY; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INJECTIONS, INTRAVENOUS; INTESTINE, SMALL; KIDNEY; MALE; PANCREAS; RATS; RATS, SPRAGUE-DAWLEY; SERINE; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0032409042     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01320899     Document Type: Article

References (22)

1. Carone FA, Nakamura S, Goldman B (1985) Urinary loss of glucose, phosphate and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid. Lab Invest 52: 605-610
2. D'Aniello A, D'Onofrio G, Pischetola M, D'Aniello G, Vetere A, Petrucelli L, Fisher GH (1993) Biological role of D-amino acid oxidase and D-aspartate oxidase. Effects of D-amino acids. J Biol Chem 268: 26941-26949
3. Dunlop DS, Neidle A, McHale D, Dunlop DM, Lajtha A (1986) The presence of free D-aspartic acid in rodents and man. Biochem Biophys Res Comm 141: 27-32
4. Dunlop DS, Neidle A (1997) The origin and turnover of D-serine in brain. Biochem Biophys Res Comm 235: 26-30
5. Drejer J, Larsson OM, Schousboe A (1983) Characterization of uptake and release processes for D- and L-aspartate in primary cultures of astrocytes and cerebellar granule cells. Neurochem Res 8: 231-243
6. Ganote CE, Peterson DR, Carone FA (1974) The nature of D-serine - induced nephrotoxicity. Am J Pathol 77: 269-282
7. Hamase K, Homma H, Takigawa Y, Fukushima T, Santa T, Imai K (1997) Regional distribution and postnatal changes of D-amino acids in rat brain. Biochim Biophys Acta 1334: 214-222
8. Hashimoto A, Kumashiro S, Nishikawa T, Oka T, Takahashi K, Mito T, Takashima S, Doi N, Mizutani Y, Yamazaki T, Kaneko T, Ootomo E (1990) Embryonic development and postnatal changes in free D-aspartate and D-serine in the human prefrontal cortex. J Neurochem 61: 348-351
9. Hashimoto A, Nishikawa T, Oka T, Takahashi K (1993) Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging. J Neurochem 60: 783-786
10. Hashimoto A, Oka T, Nishikawa T (1995a) Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis. Neuroscience 66: 635-643
11. Hashimoto A, Oka T, Nishikawa T (1995b) Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery. Eur J Neurosci 7: 1657-1663
12. Horiike K, Tojo H, Arai R, Nozaki M, Maeda T (1994) D-amino acid oxidase is confined to the lower brain stem and cerebellum in rat brain: regional differentiation of astrocytes. Brain Res 652: 297-303
13. Huang Y, Nishikawa T, Satoh K, Iwata T, Fukushima T, Santa T, Homma H, Imai K (1998) Urinary excretion of D-serine in human: comparison of different ages and species. Biol Pharm Bull 21: 156-162
14. Imai K, Fukushima T, Hagiwara K, Santa T (1995) Occurrence of D-aspartic acid in rat brain pineal gland. Biomed Chromatogr 9: 106-109
15. Imai K, Fukushima T, Santa T, Homma H, Hamase K, Sakai K, Kato M (1996) Analytical chemistry and biochemistry of D-amino acids. Biomed Chromatogr 10: 303-312
16. 14C-D-aspartic acid. Proc Japan Acid 73B: 48-52
17. Iwama H, Takahashi K, Kure S, Hayashi F, Narisawa K, Tada K, Mizoguchi M, Takashima S, Tomita U, Nishikawa T (1997) Depletion of cerebral D-serine in non-ketotic hyperglycinemia: possible involvement of glycine cleavage system in control of endogenous D-serine. Biochem Biophys Res Commun 231: 793-796
18. Kaltenbach JP, Ganote CE, Carone FA (1979) Renal tubular necrosis induced by compounds structurally related to D-serine. Exp Molec Pathol 30: 209-214
19. Kera Y, Aoyama H, Matsumura H, Hasegawa A, Nagasaki H, Yamada R (1995) Presence of free D-glutamate and D-aspartate in rat tissues. Biochim Biophys Acta 1243: 282-286
20. Neidle A, Dunlop DS (1990) Developmental changes in free D-aspartic acid in the chicken embryo and in the neonatal rat. Life Sci 46: 1517-1522
21. Schell MJ, Molliver ME, Snyder SH (1995) D-Serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proc Natl Acad Sci USA 92: 3948-3952
22. Wood PL, Hawkinson JE, Goodnough DB (1996) Formation of D-serine from L-phosphoserine in brain synaptosomes. J Neurochem 67: 1485-1490