Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2

Diabetes

Volumn 49, Issue 12, 2000, Pages 2212-2216

  Klupa, Tomasz ^a   Malecki, Maciej T ^a,c   Pezzolesi, Marcus ^a   Ji, Linong ^a,d   Curtis, Simon ^a   Langefeld, Carl D ^b   Rich, Stephen S ^b   Warram, James H ^a   Krolewski, Andrzej S ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^e JOSLIN DIABETES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CHROMOSOME 20Q; GENE LOCUS; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 0033658920     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.12.2212     Document Type: Article

References (22)

1. Mapping genes in diabetes: Genetic epidemiological perspective
2. Banting Lecture: Insulin action, diabetogenes, and the cause of type II diabetes
3. Maturity-onset diabetes of the young: Clinical heterogeneity explained by genetic heterogeneity
4. Mutations in NEUROD 1 are associated with the development of type 2 diabetes mellitus
5. A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
6. An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
7. A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians
8. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans
9. Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
10. New susceptibility locus for NIDDM is localized to human chromosome 20q
11. Exclusion of the hepatocyte nuclear factor 4α as a candidate gene for late-onset NIDDM linked with chromosome 20q
12. A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q proximal to the phosphoenolpyruvate carboxykinase gene
13. A missense mutation in hepatocyte nuclear factor-4α, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus
14. Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
15. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy
16. A physical map of the 20q12-q 13.1 region associated with type 2 diabetes
17. Allele-sharing models: LOD scores and accurate linkage tests
18. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
19. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase- 1B gene
20. Pancreatic β-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta: Inhibitory interactions with basic helix-loop-helix transcription factor E 47
21. Classification and diagnosis of diabetes mellims and other categories of glucose intolerance
22. International criteria for the diagnosis of diabetes and impaired glucose tolerance