Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-α shedding

Molecular Biology of the Cell

Volumn 20, Issue 24, 2009, Pages 5236-5249

  Myers, Timothy J ^a   Brennaman, Leann H ^a   Stevenson, Mary ^b   Higashiyama, Shigeki ^c   Russell, William E ^b   Lee, David C ^a,d   Sunnarborg, Susan Wohler ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHLOROTRIANISENE; G PROTEIN COUPLED RECEPTOR; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CHO CELL; CONTROLLED STUDY; GENETIC TRANSFECTION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

ADAM PROTEINS; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CHO CELLS; CRICETINAE; CRICETULUS; HL-60 CELLS; HUMANS; MICE; MITOCHONDRIA; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PURINERGIC P2; TRANSCRIPTIONAL ACTIVATION; TRANSFORMING GROWTH FACTOR ALPHA;

MURINAE;

EID: 73849141240     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E08-12-1256     Document Type: Article

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