Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity

Journal of Physiology

Volumn 585, Issue 3, 2007, Pages 741-758

  Duan, Yuntao ^a   Gross, Robert A ^a,b   Sheu, Shey Shing ^a,c  

^a UNIVERSITY OF ROCHESTER   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CALCIUM ION; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OLIGOMYCIN; PHOSPHOLIPASE A2; REACTIVE OXYGEN METABOLITE; ROTENONE; XANTHINE OXIDASE INHIBITOR; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE; ADPRT PROTEIN, RAT; CALCIUM; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; EXCITATORY AMINO ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM TRANSPORT; CONTROLLED STUDY; CORPUS STRIATUM; DNA DAMAGE; EMBRYO; ENZYME ACTIVATION; EXCITOTOXICITY; MITOCHONDRION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; ANIMAL TISSUE; CELL DENSITY; CENTRIFUGATION; COMET ASSAY; FLUORESCENCE MICROSCOPY; LYSOSOME; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; OXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN LOCALIZATION; WESTERN BLOTTING; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FEMALE; METABOLISM; NEOSTRIATUM; NERVE CELL; PH; PHYSIOLOGY; PREGNANCY; STATISTICAL ANALYSIS;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; COMET ASSAY; DATA INTERPRETATION, STATISTICAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; EXCITATORY AMINO ACIDS; FEMALE; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; LYSOSOMES; MITOCHONDRIA; NEOSTRIATUM; NEURONS; POLY(ADP-RIBOSE) POLYMERASES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 37249047093     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.145409     Document Type: Article

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