EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Nature

Volumn 402, Issue 6764, 1999, Pages 884-888

  Prenzel, Norbert ^a   Zwick, Esther ^a   Daub, Henrik ^a,b   Leserer, Michael ^a   Abraham, Relmar ^a   Wallasch, Christian ^a   Ullrich, Axel ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BATIMASTAT; BOMBESIN; CARBACHOL; ENDOTHELIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; LYSOPHOSPHATIDIC ACID; METALLOPROTEINASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; THROMBIN;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL COMMUNICATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIGAND BINDING; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; RAT; SIGNAL TRANSDUCTION;

ADAM PROTEINS; ANIMALS; BACTERIAL PROTEINS; CELL LINE; COS CELLS; DISINTEGRINS; EPIDERMAL GROWTH FACTOR; GTP-BINDING PROTEINS; HUMANS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; PHOSPHORYLATION; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, MUSCARINIC; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0033599039     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/47260     Document Type: Article

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