Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin

Development

Volumn 132, Issue 17, 2005, Pages 3923-3933

  Sternlicht, Mark D ^a   Sunnarborg, Susan W ^b   Kouros Mehr, Hosein ^a   Yu, Ying ^a   Lee, David C ^b   Werb, Zena ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

ADAMs; Branching morphogenesis; Epidermal growth factor receptor; ERBB; Mammary gland; Metalloproteinase; Mouse; Stromal epithelial interactions; TNF converting enzyme

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CELL; BREAST DEVELOPMENT; BREAST DUCT; BREAST EPITHELIUM; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; GENE EXPRESSION; IN VIVO STUDY; MESENCHYME; MOUSE; NEWBORN; NONHUMAN; PARACRINE SIGNALING; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STROMA CELL; TISSUE TRANSPLANTATION;

ADAM PROTEINS; ANIMALS; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MAMMARY GLANDS, ANIMAL; METALLOENDOPEPTIDASES; MICE; MICE, KNOCKOUT; MORPHOGENESIS; ORGANOIDS; PARACRINE COMMUNICATION; PHOSPHORYLATION; PHOSPHOTYROSINE; RECEPTOR, EPIDERMAL GROWTH FACTOR; STROMAL CELLS;

ANIMALIA;

EID: 26244464287     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01966     Document Type: Article

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