ERK1/2 mediate wounding- and G-protein-coupled receptor ligands - Induced EGFR activation via regulating ADAM17 and HB-EGF shedding

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 1, 2009, Pages 132-139

  Yin, Jia ^a,b   Yu, Fu Shin X ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADAM 10 INHIBITOR; ADAM 17 INHIBITOR; ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; CALCIUM; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOSERINE; PHOSPHOTYROSINE; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; SERINE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; ADAM PROTEIN; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ADENOSINE 5'-O-(3-THIOTRIPHOSPHATE); DRUG DERIVATIVE; EGFR PROTEIN, HUMAN; ENZYME INHIBITOR; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; LIGAND; LYSOPHOSPHOLIPID; SIGNAL PEPTIDE; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ARTICLE; CALCIUM TRANSPORT; CELL IMMORTALIZATION; CONTROLLED STUDY; CORNEA EPITHELIUM; EPITHELIUM CELL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MEDIATOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; TRANSACTIVATION; WESTERN BLOTTING; WOUND; WOUND HEALING; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; INJURY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ADAM PROTEINS; ADENOSINE TRIPHOSPHATE; BLOTTING, WESTERN; CALCIUM; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIUM, CORNEAL; HUMANS; IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; LYSOPHOSPHOLIPIDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, G-PROTEIN-COUPLED; SRC-FAMILY KINASES; TRANSCRIPTIONAL ACTIVATION; WOUND HEALING;

EID: 58249092162     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2246     Document Type: Article

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