-
1
-
-
0036152858
-
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
-
Asakura, M., M. Kitakaze, S. Takashima, Y. Liao, F. Ishikura, T. Yoshinaka, H. Ohmoto, K. Node, K. Yoshino, H. Ishiguro, H. Asanuma, S. Sanada, Y. Matsumura, H. Takeda, S. Beppu, M. Tada, M. Hori, and S. Higashiyama. 2002. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat. Med. 8:35-40.
-
(2002)
Nat. Med.
, vol.8
, pp. 35-40
-
-
Asakura, M.1
Kitakaze, M.2
Takashima, S.3
Liao, Y.4
Ishikura, F.5
Yoshinaka, T.6
Ohmoto, H.7
Node, K.8
Yoshino, K.9
Ishiguro, H.10
Asanuma, H.11
Sanada, S.12
Matsumura, Y.13
Takeda, H.14
Beppu, S.15
Tada, M.16
Hori, M.17
Higashiyama, S.18
-
2
-
-
0035984912
-
ROS, stress-activated kinases and stress signaling in cancer
-
Benbar, M., D. Engelberg, and A. Levitzki. 2002. ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep. 3:420-425.
-
(2002)
EMBO Rep.
, vol.3
, pp. 420-425
-
-
Benbar, M.1
Engelberg, D.2
Levitzki, A.3
-
3
-
-
0033583220
-
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi, J. S., M. C. Maa, D. A. Tice, M. E. Cox, T. H. Leu, and S. J. Parsons. 1999. c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J. Biol. Chem. 274:8335-8343.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
Cox, M.E.4
Leu, T.H.5
Parsons, S.J.6
-
4
-
-
0037084009
-
Regulation of receptor protein-tyrosine phosphatase {alpha} by oxidative stress
-
Blanchetot, C., L. G. J. Tertoolen, and J. den Hertog. 2002. Regulation of receptor protein-tyrosine phosphatase {alpha} by oxidative stress. EMBO J. 21:493-503.
-
(2002)
EMBO J.
, vol.21
, pp. 493-503
-
-
Blanchetot, C.1
Tertoolen, L.G.J.2
Den Hertog, J.3
-
5
-
-
0037416187
-
TACE is required for the activation of the EGFR by TGF-alpha in tumors
-
Borrell-Pages, M., F. Rojo, J. Albanell, J. Baselga, and J. Arribas. 2003. TACE is required for the activation of the EGFR by TGF-alpha in tumors. EMBO J. 22:1114-1124.
-
(2003)
EMBO J.
, vol.22
, pp. 1114-1124
-
-
Borrell-Pages, M.1
Rojo, F.2
Albanell, J.3
Baselga, J.4
Arribas, J.5
-
6
-
-
0028918334
-
Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
-
Burdon, R. H. 1995. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic. Biol. Med. 18:775-794.
-
(1995)
Free Radic. Biol. Med.
, vol.18
, pp. 775-794
-
-
Burdon, R.H.1
-
7
-
-
0033598131
-
Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways
-
Carpenter, G. 1999. Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J. Cell Biol. 146:697-702.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 697-702
-
-
Carpenter, G.1
-
8
-
-
0035844273
-
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation
-
Chen, K., J. A. Vita, B. C. Berk, and J. F. Keaney, Jr. 2001. c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation. J. Biol. Chem. 276:16045-16050.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16045-16050
-
-
Chen, K.1
Vita, J.A.2
Berk, B.C.3
Keaney Jr., J.F.4
-
9
-
-
0035413618
-
MAP kinases
-
Chen, Z., T. B. Gibson, F. Robinson, L. Silvestro, G. Pearson, B. Xu, A. Wright, C. Vanderbilt, and M. H. Cobb. 2001. MAP kinases. Chem. Rev. 101:2449-2476.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2449-2476
-
-
Chen, Z.1
Gibson, T.B.2
Robinson, F.3
Silvestro, L.4
Pearson, G.5
Xu, B.6
Wright, A.7
Vanderbilt, C.8
Cobb, M.H.9
-
10
-
-
0036305061
-
Stress kinase p38 mediates EGFR transactivation by hyperosmolar concentrations of sorbitol
-
Cheng, H., J. Kartenbeck, K. Kabsch, X. Mao, M. Marques, and A. Alonso. 2002. Stress kinase p38 mediates EGFR transactivation by hyperosmolar concentrations of sorbitol. J. Cell. Physiol. 192:234-243.
-
(2002)
J. Cell. Physiol.
, vol.192
, pp. 234-243
-
-
Cheng, H.1
Kartenbeck, J.2
Kabsch, K.3
Mao, X.4
Marques, M.5
Alonso, A.6
-
11
-
-
0030683639
-
Signal characteristics of G protein-transactivated EGF receptor
-
Daub, H., C. Wallasch, A. Lankenau, A. Herrlich, and A. Ullrich. 1997. Signal characteristics of G protein-transactivated EGF receptor. EMBO J. 16:7032-7044.
-
(1997)
EMBO J.
, vol.16
, pp. 7032-7044
-
-
Daub, H.1
Wallasch, C.2
Lankenau, A.3
Herrlich, A.4
Ullrich, A.5
-
12
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub, H., F. U. Weiss, C. Wallasch, and A. Ullrich. 1996. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379:557-560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
13
-
-
0036668632
-
Dealing with osmostress through MAP kinase activation
-
de Nadal, E., P. M. Alepuz, and F. Posas. 2002. Dealing with osmostress through MAP kinase activation. EMBO Rep. 3:735-740.
-
(2002)
EMBO Rep.
, vol.3
, pp. 735-740
-
-
De Nadal, E.1
Alepuz, P.M.2
Posas, F.3
-
14
-
-
0035985185
-
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: A potential role in regulated shedding
-
Diaz-Rodriguez, E., J. C. Montero, A. Esparis-Ogando, L. Yuste, and A. Pandiella. 2002. Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding. Mol. Biol. Cell 13:2031-2044.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2031-2044
-
-
Diaz-Rodriguez, E.1
Montero, J.C.2
Esparis-Ogando, A.3
Yuste, L.4
Pandiella, A.5
-
15
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
a. Elbashir, S. M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
16
-
-
0033573049
-
Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
-
Fan, H., and R. Derynck. 1999. Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J. 18:6962-6972.
-
(1999)
EMBO J.
, vol.18
, pp. 6962-6972
-
-
Fan, H.1
Derynck, R.2
-
17
-
-
0038719741
-
Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme (TACE) and of an alternatively translated polypeptide
-
Fan, H., C. W. Turck, and R. Derynck. 2003. Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme (TACE) and of an alternatively translated polypeptide. J. Biol. Chem. 278:18617-18627.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18617-18627
-
-
Fan, H.1
Turck, C.W.2
Derynck, R.3
-
18
-
-
0032053707
-
Oxygen radicals and signaling
-
Finkel, T. 1998. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10:248-253.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 248-253
-
-
Finkel, T.1
-
19
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel, T., and N. J. Holbrook. 2000. Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
20
-
-
0037371354
-
Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: Role of metalloprotease and protein kinase C-δ
-
Frank, G. D., M. Mifune, T. Inagami, M. Ohba, T. Sasaki, S. Higashiyama, P. J. Dempsey, and S. Eguchi. 2003. Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-δ. Mol. Cell. Biol. 23:1581-1589.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1581-1589
-
-
Frank, G.D.1
Mifune, M.2
Inagami, T.3
Ohba, M.4
Sasaki, T.5
Higashiyama, S.6
Dempsey, P.J.7
Eguchi, S.8
-
21
-
-
0033213984
-
The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading
-
Gechtman, Z., J. L. Alonso, G. Raab, D. E. Ingber, and M. Klagsbrun. 1999. The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J. Biol. Chem. 274:28828-28835.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28828-28835
-
-
Gechtman, Z.1
Alonso, J.L.2
Raab, G.3
Ingber, D.E.4
Klagsbrun, M.5
-
22
-
-
0038581051
-
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
-
Gschwind, A., S. Hart, O. M. Fischer, and A. Ullrich. 2003. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J. 22:2411-2421.
-
(2003)
EMBO J.
, vol.22
, pp. 2411-2421
-
-
Gschwind, A.1
Hart, S.2
Fischer, O.M.3
Ullrich, A.4
-
23
-
-
0036828287
-
Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation
-
Gschwind, A., N. Prenzel, and A. Ullrich. 2002. Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. Cancer Res. 62:6329-6336.
-
(2002)
Cancer Res.
, vol.62
, pp. 6329-6336
-
-
Gschwind, A.1
Prenzel, N.2
Ullrich, A.3
-
24
-
-
17444373968
-
A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor
-
Izumi, Y., M. Hirata, H. Hasuwa, R. Iwamoto, T. Umata, K. Miyado, Y. Tamai, T. Kurisaki, A. Sehara-Fujisawa, S. Ohno, and E. Mekada. 1998. A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. EMBO J. 17:7260-7272.
-
(1998)
EMBO J.
, vol.17
, pp. 7260-7272
-
-
Izumi, Y.1
Hirata, M.2
Hasuwa, H.3
Iwamoto, R.4
Umata, T.5
Miyado, K.6
Tamai, Y.7
Kurisaki, T.8
Sehara-Fujisawa, A.9
Ohno, S.10
Mekada, E.11
-
25
-
-
0037507267
-
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
-
Jackson, L. F., T. H. Qiu, S. W. Sunnarborg, A. Chang, C. Zhang, C. Patterson, and D. C. Lee. 2003. Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. EMBO J. 22:2704-2716.
-
(2003)
EMBO J.
, vol.22
, pp. 2704-2716
-
-
Jackson, L.F.1
Qiu, T.H.2
Sunnarborg, S.W.3
Chang, A.4
Zhang, C.5
Patterson, C.6
Lee, D.C.7
-
26
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson, G. L., and R. Lapadat. 2002. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911-1912.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
27
-
-
0035794191
-
Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway
-
Jost, M., T. M. Huggett, C. Kari, L. H. Boise, and U. Rodeck. 2001. Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway. J. Biol. Chem. 276:6320-6326.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6320-6326
-
-
Jost, M.1
Huggett, T.M.2
Kari, C.3
Boise, L.H.4
Rodeck, U.5
-
28
-
-
0032889677
-
Redox regulation of cellular signalling
-
Kamata, H., and H. Hirata. 1999. Redox regulation of cellular signalling. Cell. Signal. 11:1-14.
-
(1999)
Cell. Signal.
, vol.11
, pp. 1-14
-
-
Kamata, H.1
Hirata, H.2
-
30
-
-
0024538540
-
Ligand-independent tyrosine phosphorylation of EGF receptor and the erbB-2/neu proto-oncogene product is induced by hyperosmotic shock
-
King, C. R., I. Borrello, L. Porter, P. Comoglio, and J. Schlessinger. 1989. Ligand-independent tyrosine phosphorylation of EGF receptor and the erbB-2/neu proto-oncogene product is induced by hyperosmotic shock. Oncogene 4:13-18.
-
(1989)
Oncogene
, vol.4
, pp. 13-18
-
-
King, C.R.1
Borrello, I.2
Porter, L.3
Comoglio, P.4
Schlessinger, J.5
-
31
-
-
0029790979
-
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
-
Knebel, A., H. Rahmsdorf, A. Ullrich, and P. Herrlich. 1996. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 15:5314-5325.
-
(1996)
EMBO J.
, vol.15
, pp. 5314-5325
-
-
Knebel, A.1
Rahmsdorf, H.2
Ullrich, A.3
Herrlich, P.4
-
32
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis, J. M., and J. Avruch. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807-869.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
33
-
-
0036152681
-
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
-
Lemjabbar, H., and C. Basbaum. 2002. Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells. Nat. Med. 8:41-46.
-
(2002)
Nat. Med.
, vol.8
, pp. 41-46
-
-
Lemjabbar, H.1
Basbaum, C.2
-
34
-
-
0038339253
-
Role of the p38 MAPK pathway in cisplatin-based therapy
-
Losa, J. H., C. P. Cobo, J. G. Viniegra, V. J. Lobo, S. R. Cajal, and R. Sanchez-Prieto. 2003. Role of the p38 MAPK pathway in cisplatin-based therapy. Oncogene 22:3998-4006.
-
(2003)
Oncogene
, vol.22
, pp. 3998-4006
-
-
Losa, J.H.1
Cobo, C.P.2
Viniegra, J.G.3
Lobo, V.J.4
Cajal, S.R.5
Sanchez-Prieto, R.6
-
35
-
-
0035930617
-
Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme
-
Merlos-Suarez, A., S. Ruiz-Paz, J. Baselga, and J. Arribas. 2001. Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme. J. Biol. Chem. 276:48510-48517.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48510-48517
-
-
Merlos-Suarez, A.1
Ruiz-Paz, S.2
Baselga, J.3
Arribas, J.4
-
36
-
-
0035166859
-
Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells
-
Miyazaki, Y., S. Hiraoka, S. Tsutsui, S. Kitamura, Y. Shinomura, and Y. Matsuzawa. 2001. Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells, Gastroenterology 120:108-116.
-
(2001)
Gastroenterology
, vol.120
, pp. 108-116
-
-
Miyazaki, Y.1
Hiraoka, S.2
Tsutsui, S.3
Kitamura, S.4
Shinomura, Y.5
Matsuzawa, Y.6
-
37
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J., J. L. Slack, P. Reddy, K. L. Stocking, S. W. Sunnarborg, D. C. Lee, W. E. Russell, B. J. Castner, R. S. Johnson, J. N. Fitzner, R. W. Boyce, N. Nelson, C. J. Kozlosky, M. F. Wolfson, C. T. Rauch, D. P. Cerretti, R. J. Paxton, C. J. March, and R. A. Black. 1998. An essential role for ectodomain shedding in mammalian development. Science 282:1281-1284.
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
Russell, W.E.7
Castner, B.J.8
Johnson, R.S.9
Fitzner, J.N.10
Boyce, R.W.11
Nelson, N.12
Kozlosky, C.J.13
Wolfson, M.F.14
Rauch, C.T.15
Cerretti, D.P.16
Paxton, R.J.17
March, C.J.18
Black, R.A.19
-
38
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
Prenzel, N., O. M. Fischer, S. Streit, S. Hart, and A. Ullrich. 2001. The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Cancer 8:11-31.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
Hart, S.4
Ullrich, A.5
-
39
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel, N., E. Zwick, H. Daub, M. Leserer, R. Abraham, C. Wallasch, and A. Ullrich. 1999. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402:884-888.
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
Leserer, M.4
Abraham, R.5
Wallasch, C.6
Ullrich, A.7
-
40
-
-
0029763774
-
Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases
-
Rao, G. N. 1996. Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases. Oncogene 13:713-719.
-
(1996)
Oncogene
, vol.13
, pp. 713-719
-
-
Rao, G.N.1
-
41
-
-
0033618401
-
Cell volume-dependent regulation of L-selectin shedding in neutrophils. A role for p38 mitogen-activated protein kinase
-
Rizoli, S. B., O. D. Rotstein, and A. Kapus. 1999. Cell volume-dependent regulation of L-selectin shedding in neutrophils. A role for p38 mitogen-activated protein kinase. J. Biol. Chem. 274:22072-22080.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22072-22080
-
-
Rizoli, S.B.1
Rotstein, O.D.2
Kapus, A.3
-
42
-
-
0029860936
-
Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
-
Rosette, C., and M. Karin. 1996. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274:1194-1197.
-
(1996)
Science
, vol.274
, pp. 1194-1197
-
-
Rosette, C.1
Karin, M.2
-
43
-
-
0037623480
-
Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells
-
Ruano, M. J., S. Hernandez-Hernando, A. Jimenez, C. Estrada, and A. Villalobo. 2003. Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells. Eur. J. Biochem. 270:1828-1837.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1828-1837
-
-
Ruano, M.J.1
Hernandez-Hernando, S.2
Jimenez, A.3
Estrada, C.4
Villalobo, A.5
-
44
-
-
0034193343
-
A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents
-
Sanchez-Prieto, R., J. M. Rojas, Y. Taya, and J. S. Gutkind. 2000. A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents. Cancer Res. 60:2464-2472.
-
(2000)
Cancer Res.
, vol.60
, pp. 2464-2472
-
-
Sanchez-Prieto, R.1
Rojas, J.M.2
Taya, Y.3
Gutkind, J.S.4
-
45
-
-
0023472472
-
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schägger, H., and G. von Jargow. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166:368-379.
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schägger, H.1
Von Jargow, G.2
-
46
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger, J. 2002. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110:669-672.
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
47
-
-
0033650541
-
Assays for JNK and p38 mitogen-activated protein kinases
-
Sudo, T., and M. Karin. 2000. Assays for JNK and p38 mitogen-activated protein kinases. Methods Enzymol. 322:388-392.
-
(2000)
Methods Enzymol.
, vol.322
, pp. 388-392
-
-
Sudo, T.1
Karin, M.2
-
48
-
-
0037066757
-
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
-
Sunnarborg, S. W., C. L. Hinkle, M. Stevenson, W. E. Russell, C. S. Raska, J. J. Peschon, B. J. Castner, M. J. Gerhart, R. J. Paxton, R. A. Black, and D. C. Lee. 2002. Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J. Biol. Chem. 277:12838-12845.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12838-12845
-
-
Sunnarborg, S.W.1
Hinkle, C.L.2
Stevenson, M.3
Russell, W.E.4
Raska, C.S.5
Peschon, J.J.6
Castner, B.J.7
Gerhart, M.J.8
Paxton, R.J.9
Black, R.A.10
Lee, D.C.11
-
49
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski, T. P., and C. F. Nathan. 1991. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51:794-798.
-
(1991)
Cancer Res.
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
50
-
-
0037593847
-
The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetradecanoytphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascade
-
Takenobu, H., A. Yamazaki, M. Hirata, T. Umata, and E. Mekada. 2003. The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetradecanoytphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascade. J. Biol. Chem. 278:17255-17262.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17255-17262
-
-
Takenobu, H.1
Yamazaki, A.2
Hirata, M.3
Umata, T.4
Mekada, E.5
-
51
-
-
0033573921
-
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
-
Tice, D. A., J. S. Biscardi, A. L. Nickles, and S. J. Parsons. 1999. Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc. Natl. Acad. Sci. USA 96:1415-1420.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1415-1420
-
-
Tice, D.A.1
Biscardi, J.S.2
Nickles, A.L.3
Parsons, S.J.4
-
52
-
-
0035839427
-
A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor
-
Umata, T., M. Hirata, T. Takahashi, F. Ryu, S. Shida, Y. Takahashi, M. Tsuneoka, Y. Miura, M. Masuda, Y. Horiguchi, and E. Mekada. 2001. A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. J. Biol. Chem. 276:30475-30482.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30475-30482
-
-
Umata, T.1
Hirata, M.2
Takahashi, T.3
Ryu, F.4
Shida, S.5
Takahashi, Y.6
Tsuneoka, M.7
Miura, Y.8
Masuda, M.9
Horiguchi, Y.10
Mekada, E.11
-
53
-
-
0036170534
-
Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life
-
Weskamp, G., H. Cai, T. A. Brodie, S. Higashyama, K. Manova, T. Ludwig, and C. P. Blobel. 2002. Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Mol. Cell. Biol. 22:1537-1544.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1537-1544
-
-
Weskamp, G.1
Cai, H.2
Brodie, T.A.3
Higashyama, S.4
Manova, K.5
Ludwig, T.6
Blobel, C.P.7
-
54
-
-
0030656447
-
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
-
Yamauchi, T., K. Ueki, K. Tobe, H. Tamemoto, N. Sekine, M. Wada, M. Honjo, M. Takahashi, T. Takahashi, H. Hirai, T. Tushima, Y. Akanuma, T. Fujita, I. Komuro, Y. Yazaki, and T. Kadowaki. 1997. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature 390:91-96.
-
(1997)
Nature
, vol.390
, pp. 91-96
-
-
Yamauchi, T.1
Ueki, K.2
Tobe, K.3
Tamemoto, H.4
Sekine, N.5
Wada, M.6
Honjo, M.7
Takahashi, M.8
Takahashi, T.9
Hirai, H.10
Tushima, T.11
Akanuma, Y.12
Fujita, T.13
Komuro, I.14
Yazaki, Y.15
Kadowaki, T.16
-
55
-
-
0037157854
-
The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors
-
Yan, Y., K. Shirakabe, and Z. Werb. 2002. The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors. J. Cell Biol. 158:221-226.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 221-226
-
-
Yan, Y.1
Shirakabe, K.2
Werb, Z.3
-
56
-
-
0037604501
-
c-Jun regulates eyelid closure and skin tumor development through EGFR signaling
-
Zenz, R., H. Scheuch, P. Martin, C. Frank, R. Eferl, L. Kenner, M. Sibilia, and E. F. Wagner. 2003. c-Jun regulates eyelid closure and skin tumor development through EGFR signaling. Dev. Cell 4:879-889.
-
(2003)
Dev. Cell
, vol.4
, pp. 879-889
-
-
Zenz, R.1
Scheuch, H.2
Martin, P.3
Frank, C.4
Eferl, R.5
Kenner, L.6
Sibilia, M.7
Wagner, E.F.8
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