Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain

American Journal of Pathology

Volumn 167, Issue 4, 2005, Pages 1081-1092

  Bi, Xiaoning ^a   Liu, Jihua ^a   Yao, Yueqin ^a   Baudry, Michel ^b   Lynch, Gary ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE B; PROTEIN P105; PROTEIN P50; PROTEIN PRECURSOR; PROTEIN SUBUNIT; SYNAPTOTAGMIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; CELL LOSS; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE MUTATION; KNOCKOUT MOUSE; LIPID STORAGE; MALE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEWBORN; NIEMANN PICK DISEASE; NONHUMAN; NPC1 GENE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

EID: 26444490106     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61197-2     Document Type: Article

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