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Volumn 1685, Issue 1-3, 2004, Pages 63-76

Before the loss: Neuronal dysfunction in Niemann - Pick Type C disease

Author keywords

Cholesterol; Excitability; Morphology; Neuron; Neurotrophic factor; Niemann Pick Type C disease; Transport

Indexed keywords

NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4;

EID: 4744356190     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2004.08.012     Document Type: Review
Times cited : (49)

References (121)
  • 1
    • 0028330236 scopus 로고
    • Complementation studies in Niemannâ€"Pick disease type C indicate the existence of a second group
    • S.J. Steinberg, C.P. Ward, and A.H. Fensom Complementation studies in Niemannâ€"Pick disease type C indicate the existence of a second group J. Med. Genet. 31 1994 317 320
    • (1994) J. Med. Genet. , vol.31 , pp. 317-320
    • Steinberg, S.J.1    Ward, C.P.2    Fensom, A.H.3
  • 2
    • 0029845517 scopus 로고    scopus 로고
    • Co-cultivation of Niemannâ€"Pick disease type C fibroblasts belonging to complementation groups alpha and beta stimulates LDL-derived cholesterol esterification
    • S.J. Steinberg, D. Mondal, and A.H. Fensom Co-cultivation of Niemannâ€"Pick disease type C fibroblasts belonging to complementation groups alpha and beta stimulates LDL-derived cholesterol esterification J. Inherit. Metab. Dis. 19 6 1996 769 774
    • (1996) J. Inherit. Metab. Dis. , vol.19 , Issue.6 , pp. 769-774
    • Steinberg, S.J.1    Mondal, D.2    Fensom, A.H.3
  • 3
    • 0029655528 scopus 로고    scopus 로고
    • Genetic heterogeneity in Niemannâ€"Pick C disease: A study using somatic cell hybridization and linkage analysis
    • M.T. Vanier, S. Duthel, C. Rodriguez-LaFrasse, P. Pentchev, and E.D. Carstea Genetic heterogeneity in Niemannâ€"Pick C disease: a study using somatic cell hybridization and linkage analysis J. Hum. Genet. 58 1 1996 118 125
    • (1996) J. Hum. Genet. , vol.58 , Issue.1 , pp. 118-125
    • Vanier, M.T.1    Duthel, S.2    Rodriguez-Lafrasse, C.3    Pentchev, P.4    Carstea, E.D.5
  • 7
    • 0033840652 scopus 로고    scopus 로고
    • Regional and developmental expression of the Npc1 mRNA in the mouse brain
    • A. Prasad, W.A. Fischer, R.A. Maue, and L.P. Henderson Regional and developmental expression of the Npc1 mRNA in the mouse brain J. Neurochem. 75 2000 1250 1257
    • (2000) J. Neurochem. , vol.75 , pp. 1250-1257
    • Prasad, A.1    Fischer, W.A.2    Maue, R.A.3    Henderson, L.P.4
  • 8
    • 0000815355 scopus 로고
    • Niemannâ€"Pick Disease Type C: A cellular cholesterol lipidosis
    • Charles R. Scriver John B. Stanfoury James B. Wyngaardeb Donald S. Frederickson McGraw-Hill New York
    • P.G. Pentchev, M.T. Vanier, K. Suzuki, and M.C. Patterson Niemannâ€"Pick Disease Type C: a cellular cholesterol lipidosis Charles R. Scriver John B. Stanfoury James B. Wyngaardeb Donald S. Frederickson The Metabolic and Molecular Basis of Disease 1995 McGraw-Hill New York
    • (1995) The Metabolic and Molecular Basis of Disease
    • Pentchev, P.G.1    Vanier, M.T.2    Suzuki, K.3    Patterson, M.C.4
  • 10
    • 0000452327 scopus 로고    scopus 로고
    • Regional variation in cholesterol synthesis and low density lipoprotein transport in the brain of the fetus, newborn, and adult animal
    • S.D. Turley, and J.M. Dietschy Regional variation in cholesterol synthesis and low density lipoprotein transport in the brain of the fetus, newborn, and adult animal Nutr. Metab. Cardiovasc. Dis. 7 1997 195 201
    • (1997) Nutr. Metab. Cardiovasc. Dis. , vol.7 , pp. 195-201
    • Turley, S.D.1    Dietschy, J.M.2
  • 11
    • 0033792318 scopus 로고    scopus 로고
    • Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles
    • C. Thiele, M.J. Hannah, F. Fahrenholz, and W.B. Huttner Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles Nat. Cell Biol. 2 2000 42 49
    • (2000) Nat. Cell Biol. , vol.2 , pp. 42-49
    • Thiele, C.1    Hannah, M.J.2    Fahrenholz, F.3    Huttner, W.B.4
  • 13
    • 0037429703 scopus 로고    scopus 로고
    • Role of cholesterol in synapse formation and function
    • F.W. Pfrieger Role of cholesterol in synapse formation and function Biochim. Biophys. Acta 1610 2003 271 280
    • (2003) Biochim. Biophys. Acta , vol.1610 , pp. 271-280
    • Pfrieger, F.W.1
  • 14
    • 0032421354 scopus 로고    scopus 로고
    • Functions of lipid rafts in biological membranes
    • D.A. Brown, and E. London Functions of lipid rafts in biological membranes Annu. Rev. Cell Dev. Biol. 14 1 1998 111 136
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , Issue.1 , pp. 111-136
    • Brown, D.A.1    London, E.2
  • 15
    • 0034529050 scopus 로고    scopus 로고
    • How cells handle cholesterol
    • K. Simons, and E. Ikonen How cells handle cholesterol Science 290 5497 2000 1721 1726
    • (2000) Science , vol.290 , Issue.5497 , pp. 1721-1726
    • Simons, K.1    Ikonen, E.2
  • 16
    • 0036768289 scopus 로고    scopus 로고
    • Lipid rafts at postsynaptic sites: Distribution, function, and linkage to postsynaptic density
    • T. Suzuki Lipid rafts at postsynaptic sites: distribution, function, and linkage to postsynaptic density Neurosci. Res. 44 2002 1 9
    • (2002) Neurosci. Res. , vol.44 , pp. 1-9
    • Suzuki, T.1
  • 17
    • 0036801360 scopus 로고    scopus 로고
    • Lipid rafts and the control of neurotrophic factor signaling in the nervous system: Variations on a theme
    • G. Paratcha, and C.F. Ibanez Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme Curr. Opin. Neurobiol. 12 5 2002 542 549
    • (2002) Curr. Opin. Neurobiol. , vol.12 , Issue.5 , pp. 542-549
    • Paratcha, G.1    Ibanez, C.F.2
  • 21
    • 0034733750 scopus 로고    scopus 로고
    • Embryonic striatal neurons from Niemannâ€"Pick Type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness
    • L.P. Henderson, L. Lin, A. Prasad, C.A. Paul, T.-Y. Chang, and R.A. Maue Embryonic striatal neurons from Niemannâ€"Pick Type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness J. Biol. Chem. 275 26 2000 20179 20187
    • (2000) J. Biol. Chem. , vol.275 , Issue.26 , pp. 20179-20187
    • Henderson, L.P.1    Lin, L.2    Prasad, A.3    Paul, C.A.4    Chang, T.-Y.5    Maue, R.A.6
  • 22
    • 0036896284 scopus 로고    scopus 로고
    • Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemannâ€"Pick C1-deficient neurons
    • B. Karten, D. Vance, R. Campenot, and J. Vance Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemannâ€" Pick C1-deficient neurons J. Neurochem. 83 5 2002 1154 1163
    • (2002) J. Neurochem. , vol.83 , Issue.5 , pp. 1154-1163
    • Karten, B.1    Vance, D.2    Campenot, R.3    Vance, J.4
  • 23
    • 0037423184 scopus 로고    scopus 로고
    • Trafficking of cholesterol from cell bodies to distal axons in Niemannâ€"Pick C1-deficient neurons
    • B. Karten, D.E. Vance, R.B. Campenot, and J.E. Vance Trafficking of cholesterol from cell bodies to distal axons in Niemannâ€"Pick C1-deficient neurons J. Biol. Chem. 278 6 2003 4168 4175
    • (2003) J. Biol. Chem. , vol.278 , Issue.6 , pp. 4168-4175
    • Karten, B.1    Vance, D.E.2    Campenot, R.B.3    Vance, J.E.4
  • 25
    • 1542513994 scopus 로고    scopus 로고
    • A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemannâ€"Pick Type C1 mouse brain
    • P.C. Reid, N. Sakashita, S. Sugii, Y. Ohno-Iwashita, Y. Shimada, W.F. Hickey, and T.Y. Chang A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemannâ€"Pick Type C1 mouse brain J. Lipid Res. 45 3 2004 582 591
    • (2004) J. Lipid Res. , vol.45 , Issue.3 , pp. 582-591
    • Reid, P.C.1    Sakashita, N.2    Sugii, S.3    Ohno-Iwashita, Y.4    Shimada, Y.5    Hickey, W.F.6    Chang, T.Y.7
  • 26
    • 0034158443 scopus 로고    scopus 로고
    • Niemannâ€"Pick Type C mutations cause lipid traffic jam
    • L. Liscum Niemannâ€"Pick Type C mutations cause lipid traffic jam Traffic 1 2000 218 225
    • (2000) Traffic , vol.1 , pp. 218-225
    • Liscum, L.1
  • 28
    • 0037396865 scopus 로고    scopus 로고
    • Understanding Niemannâ€"Pick Type C disease: A fat problem
    • I. Vincent, B. Bu, and R.P. Erickson Understanding Niemann†"Pick Type C disease: a fat problem Curr. Opin. Neurol. 16 2003 155 161
    • (2003) Curr. Opin. Neurol. , vol.16 , pp. 155-161
    • Vincent, I.1    Bu, B.2    Erickson, R.P.3
  • 31
    • 0035142802 scopus 로고    scopus 로고
    • Neurons in Niemannâ€"Pick Type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations
    • M. Zervas, K. Dobrenis, and S. Walkley Neurons in Niemann†"Pick Type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations J. Neuropathol. Exp. Neurol. 60 1 2001 49 64
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , Issue.1 , pp. 49-64
    • Zervas, M.1    Dobrenis, K.2    Walkley, S.3
  • 32
    • 0030876712 scopus 로고    scopus 로고
    • GABAergic neuroaxonal dystrophy and other cytopathological alterations in feline Niemannâ€"Pick disease type C
    • P. March, M.A. Thrall, D. Brown, T. Mitchell, A. Lowenthal, and S. Walkley GABAergic neuroaxonal dystrophy and other cytopathological alterations in feline Niemannâ€"Pick disease type C Acta Neuropathol. (Berl.) 94 2 1997 164 172
    • (1997) Acta Neuropathol. (Berl.) , vol.94 , Issue.2 , pp. 164-172
    • March, P.1    Thrall, M.A.2    Brown, D.3    Mitchell, T.4    Lowenthal, A.5    Walkley, S.6
  • 33
    • 0028929548 scopus 로고
    • Neurofibrillary tangles in Niemannâ€"Pick disease type C
    • S. Love, L.R. Bridges, and C.P. Case Neurofibrillary tangles in Niemannâ€"Pick disease type C Brain 118 1995 119 129
    • (1995) Brain , vol.118 , pp. 119-129
    • Love, S.1    Bridges, L.R.2    Case, C.P.3
  • 34
    • 0036968946 scopus 로고    scopus 로고
    • Niemannâ€"Pick Disease Type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles
    • B. Bu, H. Klunemann, K. Suzuki, J. Li, T. Bird, L.W. Jin, and I. Vincent Niemannâ€"Pick Disease Type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles Neurobiol. Dis. 11 2002 285 297
    • (2002) Neurobiol. Dis. , vol.11 , pp. 285-297
    • Bu, B.1    Klunemann, H.2    Suzuki, K.3    Li, J.4    Bird, T.5    Jin, L.W.6    Vincent, I.7
  • 35
    • 0036273260 scopus 로고    scopus 로고
    • Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons
    • Q.-W. Fan, W. Yu, J.-S. Gong, K. Zou, N. Sawamura, T. Senda, K. Yanagisawa, and M. Michikawa Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons J. Neurochem. 80 1 2002 178 190
    • (2002) J. Neurochem. , vol.80 , Issue.1 , pp. 178-190
    • Fan, Q.-W.1    Yu, W.2    Gong, J.-S.3    Zou, K.4    Sawamura, N.5    Senda, T.6    Yanagisawa, K.7    Michikawa, M.8
  • 36
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: Elusive or illusive?
    • S. Munro Lipid rafts: elusive or illusive? Cell 115 2003 377 388
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 37
    • 0034625373 scopus 로고    scopus 로고
    • Structure and function of sphingolipid- and cholesterol-rich membrane rafts
    • D.A. Brown, and E. London Structure and function of sphingolipid- and cholesterol-rich membrane rafts J. Biol. Chem. 275 2000 17221 17224
    • (2000) J. Biol. Chem. , vol.275 , pp. 17221-17224
    • Brown, D.A.1    London, E.2
  • 41
    • 0031034679 scopus 로고    scopus 로고
    • Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane
    • C. Wu, S. Butz, Y.-S. Ying, and R.G.W. Anderson Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane J. Biol. Chem. 272 6 1997 3554 3559
    • (1997) J. Biol. Chem. , vol.272 , Issue.6 , pp. 3554-3559
    • Wu, C.1    Butz, S.2    Ying, Y.-S.3    Anderson, R.G.W.4
  • 42
    • 0032516835 scopus 로고    scopus 로고
    • Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK)
    • T. Furuchi, and R.G.W. Anderson Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK) J. Biol. Chem. 273 33 1998 21099 21104
    • (1998) J. Biol. Chem. , vol.273 , Issue.33 , pp. 21099-21104
    • Furuchi, T.1    Anderson, R.G.W.2
  • 43
    • 1842557804 scopus 로고    scopus 로고
    • Lipid rafts mediate chemotropic guidance of nerve growth cones
    • C. Guirland, S. Suzuki, M. Kojima, B. Lu, and J.Q. Zheng Lipid rafts mediate chemotropic guidance of nerve growth cones Neuron 42 2004 51 62
    • (2004) Neuron , vol.42 , pp. 51-62
    • Guirland, C.1    Suzuki, S.2    Kojima, M.3    Lu, B.4    Zheng, J.Q.5
  • 44
    • 0032584212 scopus 로고    scopus 로고
    • Neuronal polarity: Essential role of proteinâ€"lipid complexes in axonal sorting
    • M.D. Ledesma, K. Simons, and C.G. Dotti Neuronal polarity: essential role of proteinâ€"lipid complexes in axonal sorting Proc. Natl. Acad. Sci. 95 7 1998 3966 3971
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , Issue.7 , pp. 3966-3971
    • Ledesma, M.D.1    Simons, K.2    Dotti, C.G.3
  • 47
    • 0345130002 scopus 로고    scopus 로고
    • Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of proteinâ€"lipid complexes
    • M.D. Ledesma, B. Brugger, C. Bunning, F.T. Wieland, and C.G. Dotti Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of proteinâ€"lipid complexes EMBO J. 18 7 1999 1761 1771
    • (1999) EMBO J. , vol.18 , Issue.7 , pp. 1761-1771
    • Ledesma, M.D.1    Brugger, B.2    Bunning, C.3    Wieland, F.T.4    Dotti, C.G.5
  • 48
    • 2442440946 scopus 로고    scopus 로고
    • Reduced sensitivity of Niemannâ€"Pick Type C1-deficient cells to omega-toxin (perfringolysin O): Sequestration of toxin to raft-enriched membrane vesicles
    • Y. Ohsaki, Y. Sugimoto, M. Suzuki, T. Kaidoh, Y. Shimada, Y. Ohno-Iwashita, J.P. Davies, Y.A. Ioannou, K. Ohno, and H. Ninomiya Reduced sensitivity of Niemannâ€"Pick Type C1-deficient cells to omega-toxin (perfringolysin O): sequestration of toxin to raft-enriched membrane vesicles Histol. Cell Biol. 121 4 2004 263 272
    • (2004) Histol. Cell Biol. , vol.121 , Issue.4 , pp. 263-272
    • Ohsaki, Y.1    Sugimoto, Y.2    Suzuki, M.3    Kaidoh, T.4    Shimada, Y.5    Ohno-Iwashita, Y.6    Davies, J.P.7    Ioannou, Y.A.8    Ohno, K.9    Ninomiya, H.10
  • 49
    • 0030666672 scopus 로고    scopus 로고
    • Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemannâ€" Pick disease type C
    • W.S. Garver, R.P. Erickson, J.M. Wilson, T.L. Colton, G.S. Hossain, M.A. Kozloski, and R.A. Heidenreich Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemannâ€"Pick disease type C Biochim. Biophys. Acta 1361 1997 272 280
    • (1997) Biochim. Biophys. Acta , vol.1361 , pp. 272-280
    • Garver, W.S.1    Erickson, R.P.2    Wilson, J.M.3    Colton, T.L.4    Hossain, G.S.5    Kozloski, M.A.6    Heidenreich, R.A.7
  • 50
    • 0034988887 scopus 로고    scopus 로고
    • Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane
    • S. Lusa, T.S. Blom, E.-L. Eskelinen, E. Kuismanen, J.-E. Mansson, K. Simons, and E. Ikonen Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane J. Cell. Sci. 114 2001 1893 1900
    • (2001) J. Cell. Sci. , vol.114 , pp. 1893-1900
    • Lusa, S.1    Blom, T.S.2    Eskelinen, E.-L.3    Kuismanen, E.4    Mansson, J.-E.5    Simons, K.6    Ikonen, E.7
  • 52
    • 0033604518 scopus 로고    scopus 로고
    • Neurotrophin signaling via Trks and p75
    • W.J. Friedman, and L.A. Greene Neurotrophin signaling via Trks and p75 Exp. Cell Res. 253 1 1999 131 142
    • (1999) Exp. Cell Res. , vol.253 , Issue.1 , pp. 131-142
    • Friedman, W.J.1    Greene, L.A.2
  • 53
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in signal transduction
    • E.J. Huang, and L.F. Reichardt Trk receptors: roles in signal transduction Annu. Rev. Biochem. 72 2003 609 642
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 54
    • 0034871475 scopus 로고    scopus 로고
    • Neurotrophins and neuronal differentiation in the central nervous system
    • A.K. McAllister Neurotrophins and neuronal differentiation in the central nervous system Cell. Mol. Life Sci. 58 2001 1054 1060
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 1054-1060
    • McAllister, A.K.1
  • 55
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • M.M. Poo Neurotrophins as synaptic modulators Nat. Rev., Neurosci. 2 2001 24 32
    • (2001) Nat. Rev., Neurosci. , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 56
    • 0033625038 scopus 로고    scopus 로고
    • GFR-alpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation and neuronal survival
    • M. Tansey, R. Baloh, J. Milbrandt, and E. Johnson GFR-alpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation and neuronal survival Neuron 25 3 2000 611 623
    • (2000) Neuron , vol.25 , Issue.3 , pp. 611-623
    • Tansey, M.1    Baloh, R.2    Milbrandt, J.3    Johnson, E.4
  • 57
    • 0028800803 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro
    • R. Ventimiglia, P.E. Mather, B.E. Jones, and R.M. Lindsay The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro Eur. J. Neurosci. 7 1995 213 222
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 213-222
    • Ventimiglia, R.1    Mather, P.E.2    Jones, B.E.3    Lindsay, R.M.4
  • 58
    • 0035940491 scopus 로고    scopus 로고
    • Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemannâ€"Pick C1 deficient cells
    • Y. Sugimoto, H. Ninomiya, Y. Ohsaki, K. Higaki, J. Davies, and Y. Ioannou Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemannâ€"Pick C1 deficient cells Proc. Natl. Acad. Sci. 98 22 2001 12391 12396
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , Issue.22 , pp. 12391-12396
    • Sugimoto, Y.1    Ninomiya, H.2    Ohsaki, Y.3    Higaki, K.4    Davies, J.5    Ioannou, Y.6
  • 59
    • 0031594198 scopus 로고    scopus 로고
    • Increased levels of GM2 ganglioside in fibroblasts from a patient with juvenile Niemannâ€"Pick disease type C
    • Y. Watanabe, S. Akaboshi, G. Ishida, T. Takeshima, T. Yano, M. Taniguchi, K. Ohno, and K. Nakashima Increased levels of GM2 ganglioside in fibroblasts from a patient with juvenile Niemannâ€"Pick disease type C Brain Develop. 20 2 1998 95 97
    • (1998) Brain Develop. , vol.20 , Issue.2 , pp. 95-97
    • Watanabe, Y.1    Akaboshi, S.2    Ishida, G.3    Takeshima, T.4    Yano, T.5    Taniguchi, M.6    Ohno, K.7    Nakashima, K.8
  • 60
    • 0034801896 scopus 로고    scopus 로고
    • Site and temporal changes of gangliosides GM1/GM2 storage in the Niemannâ€"Pick disease type C mouse brain
    • M. Taniguchi, Y. Shinoda, H. Ninomiya, M. Vanier, and K. Ohno Site and temporal changes of gangliosides GM1/GM2 storage in the Niemann†"Pick disease type C mouse brain Brain Develop. 23 6 2001 414 421
    • (2001) Brain Develop. , vol.23 , Issue.6 , pp. 414-421
    • Taniguchi, M.1    Shinoda, Y.2    Ninomiya, H.3    Vanier, M.4    Ohno, K.5
  • 62
    • 0029047948 scopus 로고
    • GM1 ganglioside activates the high-affinity nerve growth factor receptor trkA
    • S.J. Rabin, and I. Mocchetti GM1 ganglioside activates the high-affinity nerve growth factor receptor trkA J. Neurochem. 65 1 1995 347 354
    • (1995) J. Neurochem. , vol.65 , Issue.1 , pp. 347-354
    • Rabin, S.J.1    Mocchetti, I.2
  • 63
    • 0029058009 scopus 로고
    • Ganglioside GM1 binds to the Trk protein and regulates receptor function
    • T. Mutoh, A. Tokuda, T. Miyadai, M. Hamaguchi, and N. Fujiki Ganglioside GM1 binds to the Trk protein and regulates receptor function Proc. Natl. Acad. Sci. 92 11 1995 5087 5091
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , Issue.11 , pp. 5087-5091
    • Mutoh, T.1    Tokuda, A.2    Miyadai, T.3    Hamaguchi, M.4    Fujiki, N.5
  • 64
    • 0036694862 scopus 로고    scopus 로고
    • Stable transfection of GM1 synthase gene into GM1-deficient NG108-15 cells, CR-72 cells, rescues the responsiveness of TRK-neurotrophin receptor to its ligand, NGF
    • T. Mutoh, T. Hamano, S. Yano, H. Koga, H. Yamamato, K. Furukawa, and R. Ledeen Stable transfection of GM1 synthase gene into GM1-deficient NG108-15 cells, CR-72 cells, rescues the responsiveness of TRK-neurotrophin receptor to its ligand, NGF Neurochem. Res. 27 7/8 2002 801 806
    • (2002) Neurochem. Res. , vol.27 , Issue.78 , pp. 801-806
    • Mutoh, T.1    Hamano, T.2    Yano, S.3    Koga, H.4    Yamamato, H.5    Furukawa, K.6    Ledeen, R.7
  • 65
    • 0036606330 scopus 로고    scopus 로고
    • Retrograde neurotrophin signaling: Trk-ing along the axon
    • D.D. Ginty, and R.A. Segal Retrograde neurotrophin signaling: Trk-ing along the axon Curr. Opin. Neurobiol. 12 3 2002 268 274
    • (2002) Curr. Opin. Neurobiol. , vol.12 , Issue.3 , pp. 268-274
    • Ginty, D.D.1    Segal, R.A.2
  • 67
    • 0036802874 scopus 로고    scopus 로고
    • Role of glia in synapse development
    • F.W. Pfrieger Role of glia in synapse development Curr. Opin. Neurobiol. 12 2002 486 490
    • (2002) Curr. Opin. Neurobiol. , vol.12 , pp. 486-490
    • Pfrieger, F.W.1
  • 68
    • 0141867844 scopus 로고    scopus 로고
    • New roles for astrocytes: Regulation of CNS synaptogenesis
    • M. Slezak, and F.W. Pfrieger New roles for astrocytes: regulation of CNS synaptogenesis Trends Neurosci. 26 10 2003 531 535
    • (2003) Trends Neurosci. , vol.26 , Issue.10 , pp. 531-535
    • Slezak, M.1    Pfrieger, F.W.2
  • 69
    • 0141884303 scopus 로고    scopus 로고
    • Glial cells and neurotransmission: An inclusive view of synaptic function
    • D.S. Auld, and R. Robitaille Glial cells and neurotransmission: an inclusive view of synaptic function Neuron 40 2003 389 400
    • (2003) Neuron , vol.40 , pp. 389-400
    • Auld, D.S.1    Robitaille, R.2
  • 70
    • 0029958248 scopus 로고    scopus 로고
    • Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein
    • A.M. Fagan, G. Bu, Y. Sun, A. Daughtery, and D.M. Holtzman Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein J. Biol. Chem. 27 47 1996 30121 30125
    • (1996) J. Biol. Chem. , vol.27 , Issue.47 , pp. 30121-30125
    • Fagan, A.M.1    Bu, G.2    Sun, Y.3    Daughtery, A.4    Holtzman, D.M.5
  • 71
    • 0037154858 scopus 로고    scopus 로고
    • Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
    • B.P. Nathan, Y. Jiang, G.K. Wong, F. Shen, G.J. Brewer, and R.G. Struble Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein Brain Res. 928 1â€"2 2002 96 105
    • (2002) Brain Res. , vol.928 , Issue.12 , pp. 96-105
    • Nathan, B.P.1    Jiang, Y.2    Wong, G.K.3    Shen, F.4    Brewer, G.J.5    Struble, R.G.6
  • 72
    • 0034975285 scopus 로고    scopus 로고
    • Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth
    • R.B. Demattos, L.L. Rudel, and D.L. Williams Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth J. Lipid Res. 42 6 2001 976 987
    • (2001) J. Lipid Res. , vol.42 , Issue.6 , pp. 976-987
    • Demattos, R.B.1    Rudel, L.L.2    Williams, D.L.3
  • 73
    • 1842790914 scopus 로고    scopus 로고
    • Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmentalized cultures
    • H. Hayashi, R.B. Campenot, D.E. Vance, and J.E. Vance Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmentalized cultures J. Biol. Chem. 279 2004 14009 14015
    • (2004) J. Biol. Chem. , vol.279 , pp. 14009-14015
    • Hayashi, H.1    Campenot, R.B.2    Vance, D.E.3    Vance, J.E.4
  • 74
    • 0027298061 scopus 로고
    • Cholesterol synthesis and lipoprotein reuptake during synaptic remodeling in hippocampus in adult rats
    • J. Poirer, A. Baccichet, D. Dea, and S. Gauthier Cholesterol synthesis and lipoprotein reuptake during synaptic remodeling in hippocampus in adult rats Neuroscience 55 1 1993 81 90
    • (1993) Neuroscience , vol.55 , Issue.1 , pp. 81-90
    • Poirer, J.1    Baccichet, A.2    Dea, D.3    Gauthier, S.4
  • 75
    • 0035875555 scopus 로고    scopus 로고
    • Glia-derived signals induce synapse formation in neurons of the rat central nervous system
    • K. Nagler, D.H. Mauch, and F.W. Pfrieger Glia-derived signals induce synapse formation in neurons of the rat central nervous system J. Physiol. 533 2001 665 679
    • (2001) J. Physiol. , vol.533 , pp. 665-679
    • Nagler, K.1    Mauch, D.H.2    Pfrieger, F.W.3
  • 78
    • 0033159778 scopus 로고    scopus 로고
    • Neurosteroids in the cerebellar Purkinje neuron and their actions (Review)
    • K. Tsutsui, and K. Ukena Neurosteroids in the cerebellar Purkinje neuron and their actions (Review) Int. J. Mol. Med. 4 1999 49 56
    • (1999) Int. J. Mol. Med. , vol.4 , pp. 49-56
    • Tsutsui, K.1    Ukena, K.2
  • 79
    • 0842320913 scopus 로고    scopus 로고
    • Postnatal development of inflammation in a murine model of Niemannâ€"Pick type C disease: Immunohistochemical observations of microglia and astroglia
    • M. Baudry, Y. Yao, D. Simmons, J. Liu, and X. Bi Postnatal development of inflammation in a murine model of Niemannâ€"Pick type C disease: immunohistochemical observations of microglia and astroglia Exp. Neurol. 184 2003 887 903
    • (2003) Exp. Neurol. , vol.184 , pp. 887-903
    • Baudry, M.1    Yao, Y.2    Simmons, D.3    Liu, J.4    Bi, X.5
  • 80
    • 0042163785 scopus 로고    scopus 로고
    • Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann†"Pick type C1 mice
    • P.C. Reid, S. Sugii, and T.Y. Chang Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemannâ€"Pick type C1 mice J. Lipid Res. 44 5 2003 1010 1019
    • (2003) J. Lipid Res. , vol.44 , Issue.5 , pp. 1010-1019
    • Reid, P.C.1    Sugii, S.2    Chang, T.Y.3
  • 81
    • 0031962339 scopus 로고    scopus 로고
    • Cellular cholesterol storage in the Niemannâ€"Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D
    • S. Suresh, Z. Yan, R.C. Patel, Y.C. Patel, and S.C. Patel Cellular cholesterol storage in the Niemannâ€"Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D J. Neurochem. 70 1 1998 242 251
    • (1998) J. Neurochem. , vol.70 , Issue.1 , pp. 242-251
    • Suresh, S.1    Yan, Z.2    Patel, R.C.3    Patel, Y.C.4    Patel, S.C.5
  • 82
    • 7344229312 scopus 로고    scopus 로고
    • Ion channel redistribution and function during development of the myelinated axon
    • I. Vabnick, and P. Shrager Ion channel redistribution and function during development of the myelinated axon J. Neurobiol. 37 1 1998 80 96
    • (1998) J. Neurobiol. , vol.37 , Issue.1 , pp. 80-96
    • Vabnick, I.1    Shrager, P.2
  • 84
    • 0037071537 scopus 로고    scopus 로고
    • The p75 receptor transduces the signal from myelin-associated glycoproteins Rho
    • T. Yamashita, H. Higuchi, and M. Tohyama The p75 receptor transduces the signal from myelin-associated glycoproteins Rho J. Cell Biol. 157 4 2002 265 270
    • (2002) J. Cell Biol. , vol.157 , Issue.4 , pp. 265-270
    • Yamashita, T.1    Higuchi, H.2    Tohyama, M.3
  • 85
    • 0035807876 scopus 로고    scopus 로고
    • Neurotrophins are key mediators of the myelination program in the peripheral nervous system
    • J.R. Chan, J.M. Cosgaya, Y.J. Wu, and E.M. Shooter Neurotrophins are key mediators of the myelination program in the peripheral nervous system Proc. Natl. Acad. Sci. U. S. A. 98 25 2001 14661 14668
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.25 , pp. 14661-14668
    • Chan, J.R.1    Cosgaya, J.M.2    Wu, Y.J.3    Shooter, E.M.4
  • 88
    • 0030800371 scopus 로고    scopus 로고
    • Cholesterol reutilization during myelination of regenerating PNS axons is impaired in Niemannâ€"Pick disease type C mice
    • J.F. Goodrum, and P.G. Pentchev Cholesterol reutilization during myelination of regenerating PNS axons is impaired in Niemannâ€" Pick disease type C mice J. Neurosci. Res. 49 3 1997 389 392
    • (1997) J. Neurosci. Res. , vol.49 , Issue.3 , pp. 389-392
    • Goodrum, J.F.1    Pentchev, P.G.2
  • 89
    • 0023940276 scopus 로고
    • Cerebellar involvement in murine sphingomyelinosis: A new model of Niemannâ€"Pick disease
    • J. Tanaka, H. Nakamura, and S. Miyawaki Cerebellar involvement in murine sphingomyelinosis: a new model of Niemannâ€"Pick disease J. Neuropathol. Exp. Neurol. 47 1988 291
    • (1988) J. Neuropathol. Exp. Neurol. , vol.47 , pp. 291
    • Tanaka, J.1    Nakamura, H.2    Miyawaki, S.3
  • 90
    • 0025994607 scopus 로고
    • Reorganization of organotypic cultures of mouse cerebellum exposed to cytosine arabinoside: A timed ultrastructural study
    • F. Seil, R.M. Herndon, K.L. Tiekotter, and N.K. Blank Reorganization of organotypic cultures of mouse cerebellum exposed to cytosine arabinoside: a timed ultrastructural study J. Comp. Neurol. 313 1991 193 212
    • (1991) J. Comp. Neurol. , vol.313 , pp. 193-212
    • Seil, F.1    Herndon, R.M.2    Tiekotter, K.L.3    Blank, N.K.4
  • 91
    • 0034922123 scopus 로고    scopus 로고
    • Interactions between cerebellar Purkinje cells and their associated astrocytes
    • F.J. Seil Interactions between cerebellar Purkinje cells and their associated astrocytes Histol. Histopathol. 16 2001 955 968
    • (2001) Histol. Histopathol. , vol.16 , pp. 955-968
    • Seil, F.J.1
  • 92
    • 1242271191 scopus 로고    scopus 로고
    • PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes
    • H. Hama, C. Hara, K. Yamaguchi, and A. Miyawaki PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes Neuron 41 2004 405 415
    • (2004) Neuron , vol.41 , pp. 405-415
    • Hama, H.1    Hara, C.2    Yamaguchi, K.3    Miyawaki, A.4
  • 94
    • 0035971218 scopus 로고    scopus 로고
    • Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemannâ€" Pick type C mice
    • N. Sawamura, J.-S. Gong, W. Garver, R. Heidenreich, H. Ninomiya, K. Ohno, K. Yanagisawa, and M. Michikawa Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemannâ€"Pick type C mice J. Biol. Chem. 276 13 2001 10314 10319
    • (2001) J. Biol. Chem. , vol.276 , Issue.13 , pp. 10314-10319
    • Sawamura, N.1    Gong, J.-S.2    Garver, W.3    Heidenreich, R.4    Ninomiya, H.5    Ohno, K.6    Yanagisawa, K.7    Michikawa, M.8
  • 95
    • 0041700117 scopus 로고    scopus 로고
    • Cholesterol accumulation in NPC1-deficient neurons is gangliosdie dependent
    • M.C. Gondre-Lewis, R. McGlynn, and S.U. Walkley Cholesterol accumulation in NPC1-deficient neurons is gangliosdie dependent Curr. Biol. 13 2003 1324 1329
    • (2003) Curr. Biol. , vol.13 , pp. 1324-1329
    • Gondre-Lewis, M.C.1    McGlynn, R.2    Walkley, S.U.3
  • 96
    • 0034639928 scopus 로고    scopus 로고
    • Alleviation of neuronal ganglioside storage does not improve the clinical course of the Niemannâ€"Pick C disease mouse
    • Y. Liu, Y.-P. Wu, R. Wada, E. Neufeld, K. Mullin, A. Howard, P. Pentchev, M. Vanier, K. Suzuki, and R. Proia Alleviation of neuronal ganglioside storage does not improve the clinical course of the Niemannâ€"Pick C disease mouse Hum. Mol. Genet. 9 7 2000 1087 1092
    • (2000) Hum. Mol. Genet. , vol.9 , Issue.7 , pp. 1087-1092
    • Liu, Y.1    Wu, Y.-P.2    Wada, R.3    Neufeld, E.4    Mullin, K.5    Howard, A.6    Pentchev, P.7    Vanier, M.8    Suzuki, K.9    Proia, R.10
  • 97
    • 0036703779 scopus 로고    scopus 로고
    • Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemannâ€"Pick Type C murine model
    • B. Bu, J. Li, P. Davies, and I. Vincent Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann†"Pick Type C murine model J. Neurosci. 22 15 2002 6515 6525
    • (2002) J. Neurosci. , vol.22 , Issue.15 , pp. 6515-6525
    • Bu, B.1    Li, J.2    Davies, P.3    Vincent, I.4
  • 99
    • 0035882468 scopus 로고    scopus 로고
    • Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis
    • H. Sakamoto, K. Ukena, and K. Tsutsu Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis J. Neurosci. 21 16 2001 6221 6232
    • (2001) J. Neurosci. , vol.21 , Issue.16 , pp. 6221-6232
    • Sakamoto, H.1    Ukena, K.2    Tsutsu, K.3
  • 100
    • 0030938811 scopus 로고    scopus 로고
    • A receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model
    • A receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model J. Physiol. (Lond.) 500 2 1997 475 485
    • (1997) J. Physiol. (Lond.) , vol.500 , Issue.2 , pp. 475-485
    • Poisbeau, P.1    Feltz, P.2    Schlichter, R.3
  • 101
    • 0037337028 scopus 로고    scopus 로고
    • Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats
    • C. Leranth, O. Petnehazy, and N.J. MacLusky Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats J. Neurosci. 23 5 2003 1588 1592
    • (2003) J. Neurosci. , vol.23 , Issue.5 , pp. 1588-1592
    • Leranth, C.1    Petnehazy, O.2    MacLusky, N.J.3
  • 102
    • 1242316279 scopus 로고    scopus 로고
    • Niemannâ€"Pick Type C disease and Alzheimer's disease: The APP-endosome connection fattens up
    • R.A. Nixon Niemann - Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up Am. J. Pathol. 164 3 2004 757 761
    • (2004) Am. J. Pathol. , vol.164 , Issue.3 , pp. 757-761
    • Nixon, R.A.1
  • 103
    • 1242316263 scopus 로고    scopus 로고
    • Intracellular accumulation of amyloidogenic fragments of amyloid-β-precursor protein in neurons with Niemann - Pick Type C defects is associated with endosomal abnormalities
    • L.W. Jin, I. Maezawa, I. Vincent, and T. Bird Intracellular accumulation of amyloidogenic fragments of amyloid-β-precursor protein in neurons with Niemann - Pick Type C defects is associated with endosomal abnormalities Am. J. Pathol. 164 3 2004 975 985
    • (2004) Am. J. Pathol. , vol.164 , Issue.3 , pp. 975-985
    • Jin, L.W.1    Maezawa, I.2    Vincent, I.3    Bird, T.4
  • 108
    • 0141862030 scopus 로고    scopus 로고
    • Polyglutamines stop traffic: Axonal transport as a common target in neurodegenerative diseases
    • M.B. Feany, and A.R. La Spada Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases Neuron 40 2003 1 2
    • (2003) Neuron , vol.40 , pp. 1-2
    • Feany, M.B.1    La Spada, A.R.2
  • 109
    • 0037104768 scopus 로고    scopus 로고
    • The neural cell adhesion molecule regulates cell-surface delivery of G-protein-activated inwardly-rectifying potassium channels via lipid rafts
    • M. Delling, E. Wischmeyer, A. Dityatev, V. Sytnyk, R.W. Veh, A. Karschin, and M. Schachner The neural cell adhesion molecule regulates cell-surface delivery of G-protein-activated inwardly-rectifying potassium channels via lipid rafts J. Neurosci. 22 16 2002 7154 7164
    • (2002) J. Neurosci. , vol.22 , Issue.16 , pp. 7154-7164
    • Delling, M.1    Wischmeyer, E.2    Dityatev, A.3    Sytnyk, V.4    Veh, R.W.5    Karschin, A.6    Schachner, M.7
  • 111
    • 0037996880 scopus 로고    scopus 로고
    • Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability
    • H. Hering, C. Lin, and M. Sheng Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability J. Neurosci. 23 8 2003 3262 3271
    • (2003) J. Neurosci. , vol.23 , Issue.8 , pp. 3262-3271
    • Hering, H.1    Lin, C.2    Sheng, M.3
  • 112
    • 0035826727 scopus 로고    scopus 로고
    • SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis
    • L.H. Chamberlain SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis Proc. Natl. Acad. Sci. 98 2001 5619 5624
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 5619-5624
    • Chamberlain, L.H.1
  • 113
    • 0032836484 scopus 로고    scopus 로고
    • Membrane fusion and exocytosis
    • R. Jahn, and T.C. Sudhof membrane fusion and exocytosis Annu. Rev. Biochem. 68 1999 863 911
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 863-911
    • Jahn, R.1    Sudhof, T.C.2
  • 115
    • 0035341309 scopus 로고    scopus 로고
    • SNARES are concentrated in cholesterol dependent clusters that define docking and fusion sites for exocytosis
    • T. Lang, D. Bruns, D. Wenzel, D. Riedel, P. Holroyd, C. Thiele, and R. Jahn SNARES are concentrated in cholesterol dependent clusters that define docking and fusion sites for exocytosis EMBO J. 20 2001 2202 2213
    • (2001) EMBO J. , vol.20 , pp. 2202-2213
    • Lang, T.1    Bruns, D.2    Wenzel, D.3    Riedel, D.4    Holroyd, P.5    Thiele, C.6    Jahn, R.7
  • 116
    • 0033103887 scopus 로고    scopus 로고
    • EphrinB ligands recruit GRIP family PDZ adaptor proteins into rafts membrane microdomains
    • K. Bruckner, J.P. Labrador, P. Scheiffele, A. Herb, P.H. Seeburg, and R. Klein EphrinB ligands recruit GRIP family PDZ adaptor proteins into rafts membrane microdomains Neuron 22 1999 511 524
    • (1999) Neuron , vol.22 , pp. 511-524
    • Bruckner, K.1    Labrador, J.P.2    Scheiffele, P.3    Herb, A.4    Seeburg, P.H.5    Klein, R.6
  • 117
    • 0032545181 scopus 로고    scopus 로고
    • The N-terminal PDZ-containing region of postsynaptic density-95 mediates association with caveolar-like lipid domains
    • A.S. Perez, and D.S. Bredt The N-terminal PDZ-containing region of postsynaptic density-95 mediates association with caveolar-like lipid domains Neurosci. Lett. 258 1998 121 123
    • (1998) Neurosci. Lett. , vol.258 , pp. 121-123
    • Perez, A.S.1    Bredt, D.S.2
  • 118
    • 0035862961 scopus 로고    scopus 로고
    • Membrane lipid rafts are necessary for the maintenance of the α7 nicotinic acetylcholine receptor in somatic spines of ciliary neurons
    • J.L. Bruses, N. Chauvet, and U. Rutishauser Membrane lipid rafts are necessary for the maintenance of the α7 nicotinic acetylcholine receptor in somatic spines of ciliary neurons J. Neurosci. 21 2001 504 512
    • (2001) J. Neurosci. , vol.21 , pp. 504-512
    • Bruses, J.L.1    Chauvet, N.2    Rutishauser, U.3
  • 119
    • 0035218451 scopus 로고    scopus 로고
    • Effects of membrane cholesterol on the sensitivity of the GABAa receptor to GABA in acutely dissociated rat hippocampal neurons
    • T. Sooksawate, and M.A. Simmonds Effects of membrane cholesterol on the sensitivity of the GABAa receptor to GABA in acutely dissociated rat hippocampal neurons Neuropharmacology 40 2001 178 184
    • (2001) Neuropharmacology , vol.40 , pp. 178-184
    • Sooksawate, T.1    Simmonds, M.A.2
  • 120
    • 0034657194 scopus 로고    scopus 로고
    • Ion channel sequestration in central nervous system axons
    • M.N. Rasband, and P. Shrager Ion channel sequestration in central nervous system axons J. Physiol. 525 2000 63 73
    • (2000) J. Physiol. , vol.525 , pp. 63-73
    • Rasband, M.N.1    Shrager, P.2
  • 121
    • 0242363668 scopus 로고    scopus 로고
    • Looking backward to move forward: Early detection of neurodegenerative disorders
    • S.T. Dekosky, and K. Marek Looking backward to move forward: early detection of neurodegenerative disorders Science 302 2003 830 834
    • (2003) Science , vol.302 , pp. 830-834
    • Dekosky, S.T.1    Marek, K.2


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