-
1
-
-
4344707219
-
Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes
-
Acosta H, Dubourdieu M, Quinõnes W, Cáceres A, Bringaud F, Concepción JL 2004. Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes. Comp Biochem and Physiol B 138: 347-356.
-
(2004)
Comp Biochem and Physiol B
, vol.138
, pp. 347-356
-
-
Acosta, H.1
Dubourdieu, M.2
Quinõnes, W.3
Cáceres, A.4
Bringaud, F.5
Concepción, J.L.6
-
2
-
-
0025356826
-
Differential energetic metabolism during Trypanosoma cruzi differentiation. II. Hexokinase, phosphofructokinase and pyruvate kinase
-
Adroher FJ, Osuna A, Lupiáñez JÁ 1990. Differential energetic metabolism during Trypanosoma cruzi differentiation. II. Hexokinase, phosphofructokinase and pyruvate kinase. Mol Cell Biochem 94: 71-82.
-
(1990)
Mol Cell Biochem
, vol.94
, pp. 71-82
-
-
Adroher, F.J.1
Osuna, A.2
Lupiáñez, J.Á.3
-
4
-
-
22244440786
-
The Trypanosoma cruzi proteome
-
Atwood JA 3rd, Weatherly DB, Minning TA, Bundy B, Cavola C, Opperdoes FR, Orlando R, Tarleton RL 2005. The Trypanosoma cruzi proteome. Science 309: 473-476.
-
(2005)
Science
, vol.309
, pp. 473-476
-
-
Atwood III, J.A.1
Weatherly, D.B.2
Minning, T.A.3
Bundy, B.4
Cavola, C.5
Opperdoes, F.R.6
Orlando, R.7
Tarleton, R.L.8
-
5
-
-
0032029255
-
Trypanosome glucose transporters
-
Barrett MP, Tetaud E, Seyfang A, Bringaud F, Baltz T 1998. Trypanosome glucose transporters. Mol Biochem Parasitol 91: 195-205.
-
(1998)
Mol Biochem Parasitol
, vol.91
, pp. 195-205
-
-
Barrett, M.P.1
Tetaud, E.2
Seyfang, A.3
Bringaud, F.4
Baltz, T.5
-
6
-
-
0022497077
-
Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi epimastigotes
-
Beach DH, Goad LJ, Holz GG Jr 1986. Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi epimastigotes. Biochem Biophys Res Commun 136: 851-856.
-
(1986)
Biochem Biophys Res Commun
, vol.136
, pp. 851-856
-
-
Beach, D.H.1
Goad, L.J.2
Holz Jr., G.G.3
-
7
-
-
22244441812
-
The genome of the African trypanosome Trypanosoma brucei
-
Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Böhme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UCM, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth T-J, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, MacLeod A, Mooney PJ, Moule S, Martin DMA, Morgan GW, Mungall K, Norbertczak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream M-A, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CMR, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM 2005. The genome of the African trypanosome Trypanosoma brucei. Science 309: 416-422.
-
(2005)
Science
, vol.309
, pp. 416-422
-
-
Berriman, M.1
Ghedin, E.2
Hertz-Fowler, C.3
Blandin, G.4
Renauld, H.5
Bartholomeu, D.C.6
Lennard, N.J.7
Caler, E.8
Hamlin, N.E.9
Haas, B.10
Böhme, U.11
Hannick, L.12
Aslett, M.A.13
Shallom, J.14
Marcello, L.15
Hou, L.16
Wickstead, B.17
Alsmark, U.C.M.18
Arrowsmith, C.19
Atkin, R.J.20
Barron, A.J.21
Bringaud, F.22
Brooks, K.23
Carrington, M.24
Cherevach, I.25
Chillingworth, T.-J.26
Churcher, C.27
Clark, L.N.28
Corton, C.H.29
Cronin, A.30
Davies, R.M.31
Doggett, J.32
Djikeng, A.33
Feldblyum, T.34
Field, M.C.35
Fraser, A.36
Goodhead, I.37
Hance, Z.38
Harper, D.39
Harris, B.R.40
Hauser, H.41
Hostetler, J.42
Ivens, A.43
Jagels, K.44
Johnson, D.45
Johnson, J.46
Jones, K.47
Kerhornou, A.X.48
Koo, H.49
Larke, N.50
Landfear, S.51
Larkin, C.52
Leech, V.53
Line, A.54
Lord, A.55
Macleod, A.56
Mooney, P.J.57
Moule, S.58
Martin, D.M.A.59
Morgan, G.W.60
Mungall, K.61
Norbertczak, H.62
Ormond, D.63
Pai, G.64
Peacock, C.S.65
Peterson, J.66
Quail, M.A.67
Rabbinowitsch, E.68
Rajandream, M.-A.69
Reitter, C.70
Salzberg, S.L.71
Sanders, M.72
Schobel, S.73
Sharp, S.74
Simmonds, M.75
Simpson, A.J.76
Tallon, L.77
Turner, C.M.R.78
Tait, A.79
Tivey, A.R.80
van Aken, S.81
Walker, D.82
Wanless, D.83
Wang, S.84
White, B.85
White, O.86
Whitehead, S.87
Woodward, J.88
Wortman, J.89
Adams, M.D.90
Embley, T.M.91
Gull, K.92
Ullu, E.93
Barry, J.D.94
Fairlamb, A.H.95
Opperdoes, F.96
Barrell, B.G.97
Donelson, J.E.98
Hall, N.99
more..
-
8
-
-
33746919619
-
Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase
-
Beswick TC, Willert EK, Phillips MA 2006. Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. Biochemistry 45: 7797-7807.
-
(2006)
Biochemistry
, vol.45
, pp. 7797-7807
-
-
Beswick, T.C.1
Willert, E.K.2
Phillips, M.A.3
-
9
-
-
44349123076
-
Chagas disease cardiomyopathy: Current concepts of an old disease
-
Bilate AM, Cunha-Neto E 2008. Chagas disease cardiomyopathy: current concepts of an old disease. Rev Inst Med Trop Sao Paulo 50: 67-74.
-
(2008)
Rev Inst Med Trop Sao Paulo
, vol.50
, pp. 67-74
-
-
Bilate, A.M.1
Cunha-Neto, E.2
-
10
-
-
43949095150
-
Identification of a new class of nonpeptidic inhibitors of cruzain
-
Brak K, Doyle PS, McKerrow JH, Ellman JA 2008. Identification of a new class of nonpeptidic inhibitors of cruzain. J Am Chem Soc 130: 6404-6410.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 6404-6410
-
-
Brak, K.1
Doyle, P.S.2
McKerrow, J.H.3
Ellman, J.A.4
-
11
-
-
0027404170
-
Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei
-
Bringaud F, Baltz T 1993. Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei. Mol Cell Biol 13: 1146-1154.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1146-1154
-
-
Bringaud, F.1
Baltz, T.2
-
12
-
-
33745810581
-
Energy metabolism of trypanosomatids: Adaptation to available carbon sources
-
Bringaud F, Rivière L, Coustou V 2006. Energy metabolism of trypanosomatids: adaptation to available carbon sources. Mol Biochem Parasitol 149: 1-9.
-
(2006)
Mol Biochem Parasitol
, vol.149
, pp. 1-9
-
-
Bringaud, F.1
Rivière, L.2
Coustou, V.3
-
13
-
-
34249685010
-
Mevalonate pathway: A review of clinical and therapeutical implications
-
Buhaescu I, Izzedine H 2007. Mevalonate pathway: a review of clinical and therapeutical implications. Clin Biochem 40: 575-584.
-
(2007)
Clin Biochem
, vol.40
, pp. 575-584
-
-
Buhaescu, I.1
Izzedine, H.2
-
14
-
-
0345073638
-
Molecular and biochemical characterization of hexokinase from Trypanosoma cruzi
-
Cáceres AJ, Portillo R, Acosta H, Rosales D, Quinõnes W, Avilan L, Salazar L, Dubourdieu M, Michels PAM, Concepción JL 2003. Molecular and biochemical characterization of hexokinase from Trypanosoma cruzi. Mol Biochem Parasitol 126: 251-262.
-
(2003)
Mol Biochem Parasitol
, vol.126
, pp. 251-262
-
-
Cáceres, A.J.1
Portillo, R.2
Acosta, H.3
Rosales, D.4
Quinõnes, W.5
Avilan, L.6
Salazar, L.7
Dubourdieu, M.8
Michels, P.A.M.9
Concepción, J.L.10
-
15
-
-
20344374400
-
Aspartate transport and metabolism in the protozoan parasite Trypanosoma cruzi
-
Canepa GE, Bouvier LA, Urias U, Miranda MR, Colli W, Alves MJ, Pereira CA 2005. Aspartate transport and metabolism in the protozoan parasite Trypanosoma cruzi. FEMS Microbiol Lett 247: 65-71.
-
(2005)
Fems Microbiol Lett
, vol.247
, pp. 65-71
-
-
Canepa, G.E.1
Bouvier, L.A.2
Urias, U.3
Miranda, M.R.4
Colli, W.5
Alves, M.J.6
Pereira, C.A.7
-
16
-
-
0021666494
-
The aerobic fermentation of glucose by Trypanosoma cruzi
-
Cannata JJ, Cazzulo JJ 1984. The aerobic fermentation of glucose by Trypanosoma cruzi. Comp Biochem Physiol B 79: 297-308.
-
(1984)
Comp Biochem Physiol B
, vol.79
, pp. 297-308
-
-
Cannata, J.J.1
Cazzulo, J.J.2
-
17
-
-
40349108458
-
Discovery of potente pteridine reductase inhibitors to guide antiparasite drug development
-
Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP 2008. Discovery of potente pteridine reductase inhibitors to guide antiparasite drug development. Proc Natl Acad Sci USA 105: 1448-1453.
-
(2008)
Proc Natl Acad Sci Usa
, vol.105
, pp. 1448-1453
-
-
Cavazzuti, A.1
Paglietti, G.2
Hunter, W.N.3
Gamarro, F.4
Piras, S.5
Loriga, M.6
Allecca, S.7
Corona, P.8
McLuskey, K.9
Tulloch, L.10
Gibellini, F.11
Ferrari, S.12
Costi, M.P.13
-
18
-
-
0028258946
-
Intermediate metabolism in Trypanosoma cruzi
-
Cazzulo JJ 1994. Intermediate metabolism in Trypanosoma cruzi. J Bioenerg Biomembr 26: 157-165.
-
(1994)
J Bioenerg Biomembr
, vol.26
, pp. 157-165
-
-
Cazzulo, J.J.1
-
19
-
-
0024674189
-
On the regulatory properties of the pyruvate kinase from Trypanosoma cruzi epimastigotes
-
Cazzulo JJ, Cazzulo Franke MC, Franke de Cazzulo BM 1989. On the regulatory properties of the pyruvate kinase from Trypanosoma cruzi epimastigotes. FEMS Microbiol Lett 50: 259-263.
-
(1989)
Fems Microbiol Lett
, vol.50
, pp. 259-263
-
-
Cazzulo, J.J.1
Cazzulo Franke, M.C.2
Franke de Cazzulo, B.M.3
-
21
-
-
0034767887
-
The expression and intracellular distribution of phosphoglycerate kinase isoenzymes in Trypanosoma cruzi
-
Concepción JL, Adjé CA, Quiñones W, Chevalier N, Dubourdieu M, Michels PA 2001. The expression and intracellular distribution of phosphoglycerate kinase isoenzymes in Trypanosoma cruzi. Mol Biochem Parasitol 118: 111-121.
-
(2001)
Mol Biochem Parasitol
, vol.118
, pp. 111-121
-
-
Concepción, J.L.1
Adjé, C.A.2
Quiñones, W.3
Chevalier, N.4
Dubourdieu, M.5
Michels, P.A.6
-
22
-
-
34548492234
-
The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes
-
Cordeiro AT, Cáceres AJ, Vertommen D, Concepción JL, Michels PA, Versées W 2007. The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes. J Mol Biol 372: 1215-1226.
-
(2007)
J Mol Biol
, vol.372
, pp. 1215-1226
-
-
Cordeiro, A.T.1
Cáceres, A.J.2
Vertommen, D.3
Concepción, J.L.4
Michels, P.A.5
Versées, W.6
-
23
-
-
0036359943
-
A critical review on Chagas disease chemotherapy
-
Coura JR, Castro SL 2002. A critical review on Chagas disease chemotherapy. Mem Inst Oswaldo Cruz 97: 3-24.
-
(2002)
Mem Inst Oswaldo Cruz
, vol.97
, pp. 3-24
-
-
Coura, J.R.1
Castro, S.L.2
-
25
-
-
0015766107
-
The mechanism of acetate and pyruvate oxidation by Trypanosoma cruzi
-
de Boiso JF, Stoppani AO 1973. The mechanism of acetate and pyruvate oxidation by Trypanosoma cruzi. J Protozool 20: 673-678.
-
(1973)
J Protozool
, vol.20
, pp. 673-678
-
-
de Boiso, J.F.1
Stoppani, A.O.2
-
26
-
-
1442280871
-
From the cell biology to the development of new chemotherapeutic approaches against trypanosomatids: Dreams and reality
-
de Souza W 2002. From the cell biology to the development of new chemotherapeutic approaches against trypanosomatids: dreams and reality. Kinetoplastid Biol Dis 1: 3.
-
(2002)
Kinetoplastid Biol Dis
, vol.1
, pp. 3
-
-
de Souza, W.1
-
27
-
-
15244350590
-
Microscopy and cytochemistry of the biogenesis of the parasitophorous vacuole
-
de Souza W 2005. Microscopy and cytochemistry of the biogenesis of the parasitophorous vacuole. Histochem Cell Biol 123: 1-18.
-
(2005)
Histochem Cell Biol
, vol.123
, pp. 1-18
-
-
de Souza, W.1
-
28
-
-
39449099130
-
Strategies and results of field emission scanning electron microscopy (FE-SEM) in the study of parasitic protozoa
-
de Souza W, Campanati L, Attias M 2008. Strategies and results of field emission scanning electron microscopy (FE-SEM) in the study of parasitic protozoa. Micron 39: 77-87.
-
(2008)
Micron
, vol.39
, pp. 77-87
-
-
de Souza, W.1
Campanati, L.2
Attias, M.3
-
29
-
-
33749575561
-
Chagas disease: Successes and challenges
-
Dias JC 2006. Chagas disease: successes and challenges. Cad Saude Publica 22: 2020-2021.
-
(2006)
Cad Saude Publica
, vol.22
, pp. 2020-2021
-
-
Dias, J.C.1
-
30
-
-
0015225938
-
The lipid metabolism of blood and culture forms of Trypanosoma lewisi and Trypanosoma rhodesiense
-
Dixon H, Ginger CD, Williamson J 1971. The lipid metabolism of blood and culture forms of Trypanosoma lewisi and Trypanosoma rhodesiense. Comp Biochem Physiol B 39: 247-266.
-
(1971)
Comp Biochem Physiol B
, vol.39
, pp. 247-266
-
-
Dixon, H.1
Ginger, C.D.2
Williamson, J.3
-
32
-
-
0017857716
-
Tricarboxylic acid cycle operation at the kinetoplast-mitochondrion complex of Trypanosoma cruzi
-
Docampo R, de Boiso JF, Stoppani AO 1978. Tricarboxylic acid cycle operation at the kinetoplast-mitochondrion complex of Trypanosoma cruzi. Biochim Biophys Acta 502: 466-476.
-
(1978)
Biochim Biophys Acta
, vol.502
, pp. 466-476
-
-
Docampo, R.1
de Boiso, J.F.2
Stoppani, A.O.3
-
33
-
-
14544289062
-
Acidocalcisomes - conserved from bacteria to man
-
Docampo R, de Souza W, Miranda K, Rohloff P, Moreno SN 2005. Acidocalcisomes - conserved from bacteria to man. Nat Rev Microbiol 3: 251-261.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 251-261
-
-
Docampo, R.1
de Souza, W.2
Miranda, K.3
Rohloff, P.4
Moreno, S.N.5
-
34
-
-
35848971033
-
A cysteine protease inhibitor cures Chagas' disease in an immunodeficientmouse model of infection
-
Doyle PS, Zhou YM, Engel JC, McKerrow JH 2007. A cysteine protease inhibitor cures Chagas' disease in an immunodeficientmouse model of infection. Antimicrob Agents Chemother 51: 3932-3939.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3932-3939
-
-
Doyle, P.S.1
Zhou, Y.M.2
Engel, J.C.3
McKerrow, J.H.4
-
35
-
-
0025771198
-
Subcellular localization of glutamate dehydrogenases and alanine aminotransferase in epimastigotes of Trypanosoma cruzi
-
Duschak VG, Cazzulo JJ 1991. Subcellular localization of glutamate dehydrogenases and alanine aminotransferase in epimastigotes of Trypanosoma cruzi. FEMS Microbiol Lett 67: 131-135.
-
(1991)
Fems Microbiol Lett
, vol.67
, pp. 131-135
-
-
Duschak, V.G.1
Cazzulo, J.J.2
-
36
-
-
22244453726
-
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
-
El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran AN, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, Caler E, Cerqueira GC, Branche C, Haas B, Anupama A, Arner E, Aslund L, Attipoe P, Bontempi E, Bringaud F, Burton P, Cadag E, Campbell DA, Carrington M, Crabtree J, Darban H, da Silveira JF, de Jong P, Edwards K, Englund PT, Fazelina G, Feldblyum T, Ferella M, Frasch AC, Gull K, Horn D, Hou L, Huang Y, Kindlund E, Klingbeil M, Kluge S, Koo H, Lacerda D, Levin MJ, Lorenzi H, Louie T, Machado CR, McCulloch R, McKenna A, Mizuno Y, Mottram JC, Nelson S, Ochaya S, Osoegawa K, Pai G, Parsons M, Pentony M, Pettersson U, Pop M, Ramirez JL, Rinta J, Robertson L, Salzberg SL, Sanchez DO, Seyler A, Sharma R, Shetty J, Simpson AJ, Sisk E, Tammi MT, Tarleton R, Teixeira S, Van Aken S, Vogt C, Ward PN, Wickstead B, Wortman J, White O, Fraser CM, Stuart KD, Andersson B 2005. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309: 409-415.
-
(2005)
Science
, vol.309
, pp. 409-415
-
-
El-Sayed, N.M.1
Myler, P.J.2
Bartholomeu, D.C.3
Nilsson, D.4
Aggarwal, G.5
Tran, A.N.6
Ghedin, E.7
Worthey, E.A.8
Delcher, A.L.9
Blandin, G.10
Westenberger, S.J.11
Caler, E.12
Cerqueira, G.C.13
Branche, C.14
Haas, B.15
Anupama, A.16
Arner, E.17
Aslund, L.18
Attipoe, P.19
Bontempi, E.20
Bringaud, F.21
Burton, P.22
Cadag, E.23
Campbell, D.A.24
Carrington, M.25
Crabtree, J.26
Darban, H.27
da Silveira, J.F.28
de Jong, P.29
Edwards, K.30
Englund, P.T.31
Fazelina, G.32
Feldblyum, T.33
Ferella, M.34
Frasch, A.C.35
Gull, K.36
Horn, D.37
Hou, L.38
Huang, Y.39
Kindlund, E.40
Klingbeil, M.41
Kluge, S.42
Koo, H.43
Lacerda, D.44
Levin, M.J.45
Lorenzi, H.46
Louie, T.47
Machado, C.R.48
McCulloch, R.49
McKenna, A.50
Mizuno, Y.51
Mottram, J.C.52
Nelson, S.53
Ochaya, S.54
Osoegawa, K.55
Pai, G.56
Parsons, M.57
Pentony, M.58
Pettersson, U.59
Pop, M.60
Ramirez, J.L.61
Rinta, J.62
Robertson, L.63
Salzberg, S.L.64
Sanchez, D.O.65
Seyler, A.66
Sharma, R.67
Shetty, J.68
Simpson, A.J.69
Sisk, E.70
Tammi, M.T.71
Tarleton, R.72
Teixeira, S.73
van Aken, S.74
Vogt, C.75
Ward, P.N.76
Wickstead, B.77
Wortman, J.78
White, O.79
Fraser, C.M.80
Stuart, K.D.81
Andersson, B.82
more..
-
37
-
-
3543150722
-
Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) as a target for anti-amoebic agents
-
Espinosa A, Clark D, Stanley SL Jr 2004. Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) as a target for anti-amoebic agents. J Antimicrob Chemother 54: 56-59.
-
(2004)
J Antimicrob Chemother
, vol.54
, pp. 56-59
-
-
Espinosa, A.1
Clark, D.2
Stanley Jr., S.L.3
-
38
-
-
62149091122
-
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors
-
Freitas RF, Prokopczyk IM, Zottis A, Oliva G, Andricopulo AD, Trevisan MT, Vilegas W, Silva MG, Montanari CA 2009. Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors. Bioorg Med Chem 17: 2476-2482.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 2476-2482
-
-
Freitas, R.F.1
Prokopczyk, I.M.2
Zottis, A.3
Oliva, G.4
Andricopulo, A.D.5
Trevisan, M.T.6
Vilegas, W.7
Silva, M.G.8
Montanari, C.A.9
-
39
-
-
50649103962
-
Metal compounds for the treatment of parasitic diseases
-
Fricker SP, Mosi RM, Cameron BR, Baird I, Zhu Y, Anastassov V, Cox J, Doyle PS, Hansell E, Lau G, Langille J, Olsen M, Qin L, Skerlj R, Wong RS, Santucci Z, McKerrow JH 2008. Metal compounds for the treatment of parasitic diseases. J Inorg Biochem 102: 1839-1845.
-
(2008)
J Inorg Biochem
, vol.102
, pp. 1839-1845
-
-
Fricker, S.P.1
Mosi, R.M.2
Cameron, B.R.3
Baird, I.4
Zhu, Y.5
Anastassov, V.6
Cox, J.7
Doyle, P.S.8
Hansell, E.9
Lau, G.10
Langille, J.11
Olsen, M.12
Qin, L.13
Skerlj, R.14
Wong, R.S.15
Santucci, Z.16
McKerrow, J.H.17
-
40
-
-
47349130269
-
The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors
-
Galarreta BC, Sifuentes R, Carrillo AK, Sanchez L, Amado M del R, Maruenda H 2008. The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors. Bioorg Med Chem 16: 6689-6695.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 6689-6695
-
-
Galarreta, B.C.1
Sifuentes, R.2
Carrillo, A.K.3
Sanchez, L.4
del Amado, M.R.5
Maruenda, H.6
-
41
-
-
0031666414
-
Analogous enzymes: Independent inventions in enzyme evolution
-
Galperin MY, Walker DR, Koonin EV 1998. Analogous enzymes: independent inventions in enzyme evolution. Genome Res 8: 779-790.
-
(1998)
Genome Res
, vol.8
, pp. 779-790
-
-
Galperin, M.Y.1
Walker, D.R.2
Koonin, E.V.3
-
42
-
-
58849103628
-
In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi
-
Guimarães AC, Otto TD, Alves-Ferreira M, Miranda AB, Degrave WM 2008. In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi. Genet Mol Res 7: 872-882.
-
(2008)
Genet Mol Res
, vol.7
, pp. 872-882
-
-
Guimarães, A.C.1
Otto, T.D.2
Alves-Ferreira, M.3
Miranda, A.B.4
Degrave, W.M.5
-
43
-
-
40949137369
-
Synthesis of b-and c-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates
-
Haemers T, Wiesner J, Gießmann D, Verbrugghen T, Hillaert U, Ortmann R, Jomaa H, Link A, Schlitzerd M, Van Calenbergha S 2008. Synthesis of b-and c-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates. Bio Med Chem 16: 3361-3371.
-
(2008)
Bio Med Chem
, vol.16
, pp. 3361-3371
-
-
Haemers, T.1
Wiesner, J.2
Gießmann, D.3
Verbrugghen, T.4
Hillaert, U.5
Ortmann, R.6
Jomaa, H.7
Link, A.8
Schlitzerd, M.9
van Calenbergha, S.10
-
44
-
-
0041767564
-
Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase
-
Hannaert V, Albert MA, Rigden DJ, da Silva Giotto MT, Thiemann O, Garratt RC, Van Roy J, Opperdoes FR, Michels PA 2003. Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase. Eur J Biochem 270: 3205-3213.
-
(2003)
Eur J Biochem
, vol.270
, pp. 3205-3213
-
-
Hannaert, V.1
Albert, M.A.2
Rigden, D.J.3
da Silva Giotto, M.T.4
Thiemann, O.5
Garratt, R.C.6
van Roy, J.7
Opperdoes, F.R.8
Michels, P.A.9
-
45
-
-
34547654456
-
Targeting the polyamine biosynthetic enzymes: A promising approach to therapy of African sleeping sickness, Chagas' disease and leishmaniasis
-
Heby O, Persson L, Rentala M 2007. Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease and leishmaniasis. Amino Acids 33: 359-366.
-
(2007)
Amino Acids
, vol.33
, pp. 359-366
-
-
Heby, O.1
Persson, L.2
Rentala, M.3
-
46
-
-
30444453138
-
Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates
-
Hudock MP, Sanz-Rodriguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepcion JL, Yardley V, Croft SL, Urbina JA, Oldfield E 2006. Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. J Med Chem 49: 215-223.
-
(2006)
J Med Chem
, vol.49
, pp. 215-223
-
-
Hudock, M.P.1
Sanz-Rodriguez, C.E.2
Song, Y.3
Chan, J.M.4
Zhang, Y.5
Odeh, S.6
Kosztowski, T.7
Leon-Rossell, A.8
Concepcion, J.L.9
Yardley, V.10
Croft, S.L.11
Urbina, J.A.12
Oldfield, E.13
-
47
-
-
0037116593
-
Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase
-
Hurtado-Guerrrero R, Peña-Díaz J, Montalvetti A, Ruiz-Pérez LM, González-Pacanowska D 2002. Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase. FEBS Letters 510: 141-144.
-
(2002)
Febs Letters
, vol.510
, pp. 141-144
-
-
Hurtado-Guerrrero, R.1
Peña-Díaz, J.2
Montalvetti, A.3
Ruiz-Pérez, L.M.4
González-Pacanowska, D.5
-
48
-
-
37049017805
-
The pentose phosphate pathway in Trypanosoma cruzi: A potential target for the chemotherapy of Chagas disease
-
Igoillo-Esteve M, Maugeri D, Stern AL, Beluardi P, Cazzulo JJ 2007. The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease. An Acad Bras Cienc 79: 649-663.
-
(2007)
An Acad Bras Cienc
, vol.79
, pp. 649-663
-
-
Igoillo-Esteve, M.1
Maugeri, D.2
Stern, A.L.3
Beluardi, P.4
Cazzulo, J.J.5
-
49
-
-
33748954833
-
Fatty acid activation of the uncoupling proteins requires the presence of the central matrix loop from UCP1
-
Jiménez-Jiménez J, Ledesma A, Zaragoza P, González-Barroso MM, Rial E 2006. Fatty acid activation of the uncoupling proteins requires the presence of the central matrix loop from UCP1. Biochim Biophys Acta 1757: 1292-1296.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 1292-1296
-
-
Jiménez-Jiménez, J.1
Ledesma, A.2
Zaragoza, P.3
González-Barroso, M.M.4
Rial, E.5
-
51
-
-
0030046836
-
Trypanosoma cruzi phosphoenolpyruvate carboxykinase (ATP-dependent): Transition metal ion requirement for activity and sulfhydryl group reactivity
-
Jurado LA, Machín I, Urbina JA 1996. Trypanosoma cruzi phosphoenolpyruvate carboxykinase (ATP-dependent): transition metal ion requirement for activity and sulfhydryl group reactivity. Biochim Biophys Acta 1292: 188-196.
-
(1996)
Biochim Biophys Acta
, vol.1292
, pp. 188-196
-
-
Jurado, L.A.1
Machín, I.2
Urbina, J.A.3
-
52
-
-
33644874819
-
From genomics to chemical genomics: New developments in KEGG
-
Kanehisa M, Goto S, Hattori M, Aoki-Kinoshita KF, Itoh M, Kawashima S, Katayama T, Araki M, Hirakawa M 2006. From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res 34: D354-D357.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Kanehisa, M.1
Goto, S.2
Hattori, M.3
Aoki-Kinoshita, K.F.4
Itoh, M.5
Kawashima, S.6
Katayama, T.7
Araki, M.8
Hirakawa, M.9
-
53
-
-
0033168258
-
Integrated pathway- genome databases and their role in drug discovery
-
Karp PD, Krummenacker M, Paley S, Wagg J 1999. Integrated pathway- genome databases and their role in drug discovery. Trends Biotechnol 17: 275-281.
-
(1999)
Trends Biotechnol
, vol.17
, pp. 275-281
-
-
Karp, P.D.1
Krummenacker, M.2
Paley, S.3
Wagg, J.4
-
54
-
-
0000990606
-
Synthesis of alpha-linoleic acid by Leishmania enriettii
-
Korn ED, Greenblatt CL 1963. Synthesis of alpha-linoleic acid by Leishmania enriettii. Science 142: 1301-1303.
-
(1963)
Science
, vol.142
, pp. 1301-1303
-
-
Korn, E.D.1
Greenblatt, C.L.2
-
55
-
-
0014678296
-
The sterols of Trypanosoma cruzi and Crithidia fasciculata
-
Korn ED, Von Brand T, Tobie EJ 1969. The sterols of Trypanosoma cruzi and Crithidia fasciculata. Comp Biochem Physiol 30: 601-610.
-
(1969)
Comp Biochem Physiol
, vol.30
, pp. 601-610
-
-
Korn, E.D.1
von Brand, T.2
Tobie, E.J.3
-
56
-
-
0037963699
-
Parasite-specific trypanothione reductase as a drug target molecule
-
Krauth-Siegel RL, Inhoff O 2003. Parasite-specific trypanothione reductase as a drug target molecule. Parasitol Res 90: S77-S85.
-
(2003)
Parasitol Res
, vol.90
-
-
Krauth-Siegel, R.L.1
Inhoff, O.2
-
58
-
-
0032730353
-
Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes
-
Liendo A, Visbal G, Piras MM, Piras R, Urbina JA 1999. Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes. Mol Biochem Parasitol 104: 81-91.
-
(1999)
Mol Biochem Parasitol
, vol.104
, pp. 81-91
-
-
Liendo, A.1
Visbal, G.2
Piras, M.M.3
Piras, R.4
Urbina, J.A.5
-
59
-
-
33645883558
-
Progresses in the field of drug design to combat tropical protozoan parasitic diseases
-
Liñares GE, Ravaschino EL, Rodriguez JB 2006. Progresses in the field of drug design to combat tropical protozoan parasitic diseases. Curr Med Chem 13: 335-360.
-
(2006)
Curr Med Chem
, vol.13
, pp. 335-360
-
-
Liñares, G.E.1
Ravaschino, E.L.2
Rodriguez, J.B.3
-
60
-
-
23644451158
-
Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics
-
Lorente SO, Jimenez CJ, Gros L, Yardley V, de Luca-Fradley K, Croft SL, Urbina J, Ruiz-Perez LM, Pacanowska DG, Gilbert IH 2005. Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics. Bioorg Med Chem 13: 5435-5453.
-
(2005)
Bioorg Med Chem
, vol.13
, pp. 5435-5453
-
-
Lorente, S.O.1
Jimenez, C.J.2
Gros, L.3
Yardley, V.4
de Luca-Fradley, K.5
Croft, S.L.6
Urbina, J.7
Ruiz-Perez, L.M.8
Pacanowska, D.G.9
Gilbert, I.H.10
-
61
-
-
0142124194
-
Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi
-
Magaraci F, Jimenez CJ, Rodrigues C, Rodrigues JC, Braga MV, Yardley V, de Luca-Fradley K, Croft SL, de Souza W, Ruiz-Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH 2003. Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. J Med Chem 46: 4714-4727.
-
(2003)
J Med Chem
, vol.46
, pp. 4714-4727
-
-
Magaraci, F.1
Jimenez, C.J.2
Rodrigues, C.3
Rodrigues, J.C.4
Braga, M.V.5
Yardley, V.6
de Luca-Fradley, K.7
Croft, S.L.8
de Souza, W.9
Ruiz-Perez, L.M.10
Urbina, J.11
Gonzalez Pacanowska, D.12
Gilbert, I.H.13
-
62
-
-
45549100534
-
Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: The BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT)
-
Marin-Neto JA, Rassi A Jr, Morillo CA, Avezum A, Connolly SJ, Sosa-Estani S, Rosas F, Yusuf S 2008. Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT). Am Heart J 156: 37-43.
-
(2008)
Am Heart J
, vol.156
, pp. 37-43
-
-
Marin-Neto, J.A.1
Rassi Jr, A.2
Morillo, C.A.3
Avezum, A.4
Connolly, S.J.5
Sosa-Estani, S.6
Rosas, F.7
Yusuf, S.8
-
63
-
-
33846933089
-
High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity
-
Martyn DC, Jones DC, Fairlamb AH, Clardy J 2007. High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorg Med Chem Lett 17: 1280-1283.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 1280-1283
-
-
Martyn, D.C.1
Jones, D.C.2
Fairlamb, A.H.3
Clardy, J.4
-
64
-
-
1942502299
-
The pentose phosphate pathway in Trypanosoma cruzi
-
Maugeri DA, Cazzulo JJ 2004. The pentose phosphate pathway in Trypanosoma cruzi. FEMS Microbiol Lett 234: 117-123.
-
(2004)
Fems Microbiol Lett
, vol.234
, pp. 117-123
-
-
Maugeri, D.A.1
Cazzulo, J.J.2
-
65
-
-
33847377170
-
Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host
-
Maya JD, Cassels BK, Iturriaga-Vásquez P, Ferreira J, Faúndez M, Galanti N, Ferreira A, Morello A 2007. Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host. Comp Biochem Physiol A Mol Integr Physiol 146: 601-620.
-
(2007)
Comp Biochem Physiol a Mol Integr Physiol
, vol.146
, pp. 601-620
-
-
Maya, J.D.1
Cassels, B.K.2
Iturriaga-Vásquez, P.3
Ferreira, J.4
Faúndez, M.5
Galanti, N.6
Ferreira, A.7
Morello, A.8
-
66
-
-
0034333236
-
Metabolic aspects of glycosomes in trypanosomatidae - new data and views
-
Michels PA, Hannaert V, Bringaud F 2000. Metabolic aspects of glycosomes in trypanosomatidae - new data and views. Parasitol Today 16: 482-489.
-
(2000)
Parasitol Today
, vol.16
, pp. 482-489
-
-
Michels, P.A.1
Hannaert, V.2
Bringaud, F.3
-
67
-
-
33846690105
-
Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities
-
Mielniczki-Pereira AA, Chiavegatto CM, López JA, Colli W, Alves MJM, Gadelha FR 2007. Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities. Acta Tropica 101: 54-60.
-
(2007)
Acta Tropica
, vol.101
, pp. 54-60
-
-
Mielniczki-Pereira, A.A.1
Chiavegatto, C.M.2
López, J.A.3
Colli, W.4
Alves, M.J.M.5
Gadelha, F.R.6
-
68
-
-
0034234601
-
Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase
-
Montalvetti A, Peña-Díaz J, Hurtado R, Ruiz-Pérez LM, González- Pacanowska D 2000. Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase. Biochem J 349: 27-34.
-
(2000)
Biochem J
, vol.349
, pp. 27-34
-
-
Montalvetti, A.1
Peña-Díaz, J.2
Hurtado, R.3
Ruiz-Pérez, L.M.4
González-Pacanowska, D.5
-
69
-
-
7944224890
-
Biogenesis of peroxisomes and glycosomes: Trypanosomatid glycosome assembly is a promising new drug target
-
Moyersoen J, Choe J, Fan E, Hol WG, Michels PA 2004. Biogenesis of peroxisomes and glycosomes: trypanosomatid glycosome assembly is a promising new drug target. FEMS Microbiol Rev 28: 603-643.
-
(2004)
Fems Microbiol Rev
, vol.28
, pp. 603-643
-
-
Moyersoen, J.1
Choe, J.2
Fan, E.3
Hol, W.G.4
Michels, P.A.5
-
70
-
-
33644535470
-
Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor
-
Olivares-Illana V, Pérez-Montfort R, López-Calahorra F, Costas M, Rodríguez-Romero A, Tuena de Gómez-Puyou M, Gómez Puyou A 2006. Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor. Biochemistry 45: 2556-2560.
-
(2006)
Biochemistry
, vol.45
, pp. 2556-2560
-
-
Olivares-Illana, V.1
Pérez-Montfort, R.2
López-Calahorra, F.3
Costas, M.4
Rodríguez-Romero, A.5
Tuena de Gómez-Puyou, M.6
Gómez Puyou, A.7
-
71
-
-
47749092414
-
Perturbation of the dimer interface of triosephosphate isomerase and its effect on Trypanosoma cruzi
-
Olivares-Illana V, Rodríguez-Romero A, Becker I, Berzunza M, García J, Pérez-Montfort R, Cabrera N, López-Calahorra F, Gómez-Puyou MT, Gómez-Puyou A 2007. Perturbation of the dimer interface of triosephosphate isomerase and its effect on Trypanosoma cruzi. PLoS Negl Trop Dis 1: e1.
-
(2007)
Plos Negl Trop Dis
, vol.1
-
-
Olivares-Illana, V.1
Rodríguez-Romero, A.2
Becker, I.3
Berzunza, M.4
García, J.5
Pérez-Montfort, R.6
Cabrera, N.7
López-Calahorra, F.8
Gómez-Puyou, M.T.9
Gómez-Puyou, A.10
-
73
-
-
18044365378
-
The chemotherapy of Chagas' disease: An overview
-
Paulino M, Iribarne F, Dubin M, Aguilera-Morales S, Tapia O, Stoppani AO 2005. The chemotherapy of Chagas' disease: an overview. Mini Rev Med Chem 5: 499-519.
-
(2005)
Mini Rev Med Chem
, vol.5
, pp. 499-519
-
-
Paulino, M.1
Iribarne, F.2
Dubin, M.3
Aguilera-Morales, S.4
Tapia, O.5
Stoppani, A.O.6
-
74
-
-
0030919744
-
A soluble 3-hydroxy-3-methylglutaryl- CoA reductase in the protozoan Trypanosoma cruzi
-
Peña-Díaz J, Montalvetti A, Camacho A, Gallego C, Ruiz-Perez LM, Gonzalez-Pacanowska D 1997. A soluble 3-hydroxy-3-methylglutaryl- CoA reductase in the protozoan Trypanosoma cruzi. Biochem J 324: 619-626.
-
(1997)
Biochem J
, vol.324
, pp. 619-626
-
-
Peña-Díaz, J.1
Montalvetti, A.2
Camacho, A.3
Gallego, C.4
Ruiz-Perez, L.M.5
Gonzalez-Pacanowska, D.6
-
75
-
-
0033230875
-
L-arginine uptake and L-phosphoarginine synthesis in Trypanosoma cruzi
-
Pereira CA, Alonso GD, Paveto MC, Flawiá MM, Torres HN 1999. L-arginine uptake and L-phosphoarginine synthesis in Trypanosoma cruzi. J Eukaryot Microbiol 46: 566-570.
-
(1999)
J Eukaryot Microbiol
, vol.46
, pp. 566-570
-
-
Pereira, C.A.1
Alonso, G.D.2
Paveto, M.C.3
Flawiá, M.M.4
Torres, H.N.5
-
76
-
-
0040315151
-
Derivatization of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi as probe of the interrelationship between the catalytic sites and the dimer interface
-
Pérez-Montfort R, Garza-Ramos G, Alcántara GH, Reyes-Vivas H, Gao XG, Maldonado E, de Gómez-Puyou MT, Gómez-Puyou A 1999. Derivatization of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi as probe of the interrelationship between the catalytic sites and the dimer interface. Biochemistry 38: 4114-4120.
-
(1999)
Biochemistry
, vol.38
, pp. 4114-4120
-
-
Pérez-Montfort, R.1
Garza-Ramos, G.2
Alcántara, G.H.3
Reyes-Vivas, H.4
Gao, X.G.5
Maldonado, E.6
de Gómez-Puyou, M.T.7
Gómez-Puyou, A.8
-
77
-
-
64549124228
-
Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors
-
Perez-Pineiro R, Burgos A, Jones DC, Andrew LC, Rodriguez H, Suarez M, Fairlamb AH, Wishart DS 2009. Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors. J Med Chem 52: 1670-1680.
-
(2009)
J Med Chem
, vol.52
, pp. 1670-1680
-
-
Perez-Pineiro, R.1
Burgos, A.2
Jones, D.C.3
Andrew, L.C.4
Rodriguez, H.5
Suarez, M.6
Fairlamb, A.H.7
Wishart, D.S.8
-
78
-
-
3042570671
-
Cloning of S-adenosyl-L-methionine: C-24-Delta-sterolmethyltransferase (ERG6) from Leishmania donovani and characterization of mRNAs in wild-type and amphotericin B-Resistant promastigotes
-
Pourshafie M, Morand S, Virion A, Rakotomanga M, Dupuy C, Loiseau PM 2004. Cloning of S-adenosyl-L-methionine: C-24-Delta-sterolmethyltransferase (ERG6) from Leishmania donovani and characterization of mRNAs in wild-type and amphotericin B-Resistant promastigotes. Antimicrob Agents Chemother 48: 2409-2414.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2409-2414
-
-
Pourshafie, M.1
Morand, S.2
Virion, A.3
Rakotomanga, M.4
Dupuy, C.5
Loiseau, P.M.6
-
80
-
-
0035852995
-
Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi
-
Reyes-Vivas H, Hernández-Alcantara G, López-Velazquez G, Cabrera N, Pérez-Montfort R, de Gómez-Puyou MT, Gómez-Puyou A 2001. Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi. Biochemistry 40: 3134-3140.
-
(2001)
Biochemistry
, vol.40
, pp. 3134-3140
-
-
Reyes-Vivas, H.1
Hernández-Alcantara, G.2
López-Velazquez, G.3
Cabrera, N.4
Pérez-Montfort, R.5
de Gómez-Puyou, M.T.6
Gómez-Puyou, A.7
-
81
-
-
0037327813
-
Fatty acid and sterol metabolism: Potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa
-
Roberts CW, McLeod R, Rice DW, Ginger M, Chance ML, Goad LJ 2003. Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol 126: 129-142.
-
(2003)
Mol Biochem Parasitol
, vol.126
, pp. 129-142
-
-
Roberts, C.W.1
McLeod, R.2
Rice, D.W.3
Ginger, M.4
Chance, M.L.5
Goad, L.J.6
-
83
-
-
0036389732
-
Structure and inactivation of triosephosphate isomerase from Entamoeba histolytica
-
Rodríguez-Romero A, Hernández-Santoyo A, del Pozo Yauner L, Kornhauser A, Fernández-Velasco DA 2002. Structure and inactivation of triosephosphate isomerase from Entamoeba histolytica. J Mol Biol 322: 669-675.
-
(2002)
J Mol Biol
, vol.322
, pp. 669-675
-
-
Rodríguez-Romero, A.1
Hernández-Santoyo, A.2
del Pozo Yauner, L.3
Kornhauser, A.4
Fernández-Velasco, D.A.5
-
84
-
-
0018964687
-
Catabolic metabolism in Trypanosoma cruzi
-
Rogerson GW, Gutteridge WE 1980. Catabolic metabolism in Trypanosoma cruzi. Int J Parasitol 10: 131-135.
-
(1980)
Int J Parasitol
, vol.10
, pp. 131-135
-
-
Rogerson, G.W.1
Gutteridge, W.E.2
-
85
-
-
34250320544
-
Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: Kinetic and metabolic studies
-
Sanz-Rodriguez CE, Concepcion JL, Pekerar S, Oldfield E, Urbina JA 2007. Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies. J Biol Chem 282: 12377-12387.
-
(2007)
J Biol Chem
, vol.282
, pp. 12377-12387
-
-
Sanz-Rodriguez, C.E.1
Concepcion, J.L.2
Pekerar, S.3
Oldfield, E.4
Urbina, J.A.5
-
86
-
-
36348949834
-
Epidemiology of Chagas disease in non-endemic countries: The role of international migration
-
Schmunis GA 2007. Epidemiology of Chagas disease in non-endemic countries: the role of international migration. Mem Inst Oswaldo Cruz 102: 75-85.
-
(2007)
Mem Inst Oswaldo Cruz
, vol.102
, pp. 75-85
-
-
Schmunis, G.A.1
-
87
-
-
34247137519
-
Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase
-
Sgraja T, Smith TK, Hunter WN 2007. Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. BMC Struct Biol 7: 20.
-
(2007)
Bmc Struct Biol
, vol.7
, pp. 20
-
-
Sgraja, T.1
Smith, T.K.2
Hunter, W.N.3
-
88
-
-
16344382171
-
Amino acid metabolic routes in Trypanosoma cruzi: Possible therapeutic targets against Chagas' disease
-
Silber AM, Colli W, Ulrich H, Alves MJ, Pereira CA 2005. Amino acid metabolic routes in Trypanosoma cruzi: possible therapeutic targets against Chagas' disease. Curr Drug Targets Infect Disord 5: 53-64.
-
(2005)
Curr Drug Targets Infect Disord
, vol.5
, pp. 53-64
-
-
Silber, A.M.1
Colli, W.2
Ulrich, H.3
Alves, M.J.4
Pereira, C.A.5
-
89
-
-
32144458059
-
Biochemical characterization of the glutamate transport in Trypanosoma cruzi
-
Silber AM, Rojas RL, Urias U, Colli W, Alves MJ 2006. Biochemical characterization of the glutamate transport in Trypanosoma cruzi. Int J Parasitol 36: 157-163.
-
(2006)
Int J Parasitol
, vol.36
, pp. 157-163
-
-
Silber, A.M.1
Rojas, R.L.2
Urias, U.3
Colli, W.4
Alves, M.J.5
-
91
-
-
33846318571
-
Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: Kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism
-
Stern AL, Burgos E, Salmon L, Cazzulo JJ 2007. Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism. Biochem J 401: 279-285.
-
(2007)
Biochem J
, vol.401
, pp. 279-285
-
-
Stern, A.L.1
Burgos, E.2
Salmon, L.3
Cazzulo, J.J.4
-
92
-
-
0017108202
-
Proline metabolism in Trypanosoma cruzi epimastigotes
-
Sylvester D, Krassner SM 1976. Proline metabolism in Trypanosoma cruzi epimastigotes. Comp Biochem Physiol B 55: 443-447.
-
(1976)
Comp Biochem Physiol B
, vol.55
, pp. 443-447
-
-
Sylvester, D.1
Krassner, S.M.2
-
93
-
-
34548021449
-
Immune system recognition of Trypanosoma cruzi
-
Tarleton RL 2007. Immune system recognition of Trypanosoma cruzi. Curr Opin Immunol 19: 430-434.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 430-434
-
-
Tarleton, R.L.1
-
94
-
-
0023119021
-
Trypanosoma cruzi: Subcellular distribution of glycolytic and some related enzymes of epimastigotes
-
Taylor MB, Gutteridge WE 1987. Trypanosoma cruzi: subcellular distribution of glycolytic and some related enzymes of epimastigotes. Expt Parasitol 63: 84-97.
-
(1987)
Expt Parasitol
, vol.63
, pp. 84-97
-
-
Taylor, M.B.1
Gutteridge, W.E.2
-
95
-
-
0027936232
-
Characterization of glucose transport and cloning of a hexose transporter gene in Trypanosoma cruzi
-
Tetaud E, Bringaud F, Chabas S, Barrett MP, Baltz T 1994. Characterization of glucose transport and cloning of a hexose transporter gene in Trypanosoma cruzi. Proc Natl Acad Sci USA 91: 8278-8282.
-
(1994)
Proc Natl Acad Sci Usa
, vol.91
, pp. 8278-8282
-
-
Tetaud, E.1
Bringaud, F.2
Chabas, S.3
Barrett, M.P.4
Baltz, T.5
-
96
-
-
0032125880
-
Differences in energy metabolism between trypanosomatidae
-
Tielens AG, Van Hellemond JJ 1998. Differences in energy metabolism between trypanosomatidae. Parasitol Today 14: 265-272.
-
(1998)
Parasitol Today
, vol.14
, pp. 265-272
-
-
Tielens, A.G.1
van Hellemond, J.J.2
-
97
-
-
0035834540
-
Crystal structure of the dimeric phosphoenolpyruvate carboxykinase (PEPCK) from Trypanosoma cruzi at 2 A resolution
-
Trapani S, Linss J, Goldenberg S, Fischer H, Craievich AF, Oliva G 2001. Crystal structure of the dimeric phosphoenolpyruvate carboxykinase (PEPCK) from Trypanosoma cruzi at 2 A resolution. J Mol Biol 313: 1059-1072.
-
(2001)
J Mol Biol
, vol.313
, pp. 1059-1072
-
-
Trapani, S.1
Linss, J.2
Goldenberg, S.3
Fischer, H.4
Craievich, A.F.5
Oliva, G.6
-
98
-
-
0030921232
-
Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites
-
Urbina JA 1997. Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites. Parasitology 114: S91-S99.
-
(1997)
Parasitology
, vol.114
-
-
Urbina, J.A.1
-
99
-
-
0021287745
-
Regulation of energy metabolism in Trypanosoma (Schizotrypanum) cruzi epimastigotes. I. Hexokinase and phosphofructokinase
-
Urbina JA, Crespo A 1984. Regulation of energy metabolism in Trypanosoma (Schizotrypanum) cruzi epimastigotes. I. Hexokinase and phosphofructokinase. Mol Biochem Parasitol 11: 225-239.
-
(1984)
Mol Biochem Parasitol
, vol.11
, pp. 225-239
-
-
Urbina, J.A.1
Crespo, A.2
-
100
-
-
0142227145
-
Specific chemotherapy of Chagas disease: Controversies and advances
-
Urbina JA, Docampo R 2003. Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol 19: 495-501.
-
(2003)
Trends Parasitol
, vol.19
, pp. 495-501
-
-
Urbina, J.A.1
Docampo, R.2
-
101
-
-
0027860429
-
The limitations of paradigms: Studies on the intermediary metabolism of Trypanosoma cruzi
-
Urbina JA, Machin I, Jurado L 1993. The limitations of paradigms: studies on the intermediary metabolism of Trypanosoma cruzi. Biol Res 26: 81-88.
-
(1993)
Biol Res
, vol.26
, pp. 81-88
-
-
Urbina, J.A.1
Machin, I.2
Jurado, L.3
-
102
-
-
0025124852
-
Inhibition of phosphoenolpyruvate carboxykinase from Trypanosoma (Schizotrypanum) cruzi epimastigotes by 3-mercaptopicolinic acid: In vitro and in vivo studies
-
Urbina JA, Osorno CE, Rojas A 1990. Inhibition of phosphoenolpyruvate carboxykinase from Trypanosoma (Schizotrypanum) cruzi epimastigotes by 3-mercaptopicolinic acid: in vitro and in vivo studies. Arch Biochem Biophys 282: 91-99.
-
(1990)
Arch Biochem Biophys
, vol.282
, pp. 91-99
-
-
Urbina, J.A.1
Osorno, C.E.2
Rojas, A.3
-
103
-
-
27844449025
-
The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei
-
van Hellemond JJ, Opperdoes FR, Tielens AG 2005. The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei. Biochem Soc Trans 33: 967-971.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 967-971
-
-
van Hellemond, J.J.1
Opperdoes, F.R.2
Tielens, A.G.3
-
104
-
-
33749066538
-
Adaptations in the lipid metabolism of the protozoan parasite Trypanosoma brucei
-
van Hellemond JJ, Tielens AG 2006. Adaptations in the lipid metabolism of the protozoan parasite Trypanosoma brucei. FEBS Lett 580: 5552-5558.
-
(2006)
Febs Lett
, vol.580
, pp. 5552-5558
-
-
van Hellemond, J.J.1
Tielens, A.G.2
-
105
-
-
16844370149
-
New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle
-
van Weelden SW, van Hellemond JJ, Opperdoes FR, Tielens AG 2005. New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle. J Biol Chem 280: 12451-12460.
-
(2005)
J Biol Chem
, vol.280
, pp. 12451-12460
-
-
van Weelden, S.W.1
van Hellemond, J.J.2
Opperdoes, F.R.3
Tielens, A.G.4
-
106
-
-
72449188565
-
The utilization of Krebs cycle intermediates by the culture forms of Trypanosoma cruzi and Leishmania tropica
-
Von Brand T, Agosin M 1955. The utilization of Krebs cycle intermediates by the culture forms of Trypanosoma cruzi and Leishmania tropica. J Infect Dis 97: 274-279.
-
(1955)
J Infect Dis
, vol.97
, pp. 274-279
-
-
von Brand, T.1
Agosin, M.2
-
107
-
-
0030581670
-
Identification of 2-enoyl coenzyme A hydratase and NADP(+)- dependent 3-hydroxyacyl-CoA dehydrogenase activity in glycosomes of procyclic Trypanosoma brucei
-
Wiemer EA, IJlst L, van Roy J, Wanders RJ, Opperdoes FR 1996. Identification of 2-enoyl coenzyme A hydratase and NADP(+)- dependent 3-hydroxyacyl-CoA dehydrogenase activity in glycosomes of procyclic Trypanosoma brucei. Mol Biochem Parasitol 82: 107-111.
-
(1996)
Mol Biochem Parasitol
, vol.82
, pp. 107-111
-
-
Wiemer, E.A.1
Ijlst, L.2
van Roy, J.3
Wanders, R.J.4
Opperdoes, F.R.5
-
108
-
-
33846020045
-
Isoprenoid biosynthesis of the apicoplast as drug target
-
Wiesner J, Jomaa H 2007. Isoprenoid biosynthesis of the apicoplast as drug target. Curr Drug Targets 8: 3-13.
-
(2007)
Curr Drug Targets
, vol.8
, pp. 3-13
-
-
Wiesner, J.1
Jomaa, H.2
|