Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 18, 2005, Pages 5435-5453

  Lorente, Silvia Orenes ^a   Jimenez, Carmen Jimenez ^b   Gros, Ludovic ^a   Yardley, Vanessa ^c   De Luca Fradley, Kate ^c   Croft, Simon L ^c   Urbina, Julio A ^d   Ruiz Perez, Luis M ^b   Pacanowska, Dolores Gonzalez ^b   Gilbert, Ian H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA ACETOXY 23,24 BISNORCHOL 5 EN 22 BENZYLAMINE; 3BETA ACETOXY 23,24 BISNORCHOL 5 EN 22 BUTYLAMINE; 3BETA ACETOXY 23,24 BISNORCHOL 5 EN 22 OXO 22 BENZYLAMINE; 3BETA ACETOXY 23,24 BISNORCHOL 5 EN 22 OXO 22 BUTYLAMINE; 3BETA ACETOXY 23,24 BISNORCHOL 5 EN 22 PIPERIDYLAMINE; 3BETA ACETOXY 23,24 BISNORCHOLEN 22 OXO 22 PIPERIDYLAMINE; 3BETA HYDROXY 23,24 BISNORCHOL 5 EN 22 OXO 22 BENZYLAMINE; 3BETA HYDROXY 23,24 BISNORCHOL 5 EN 22 OXO 22 BUTYLAMINE; 3BETA HYDROXY 23,24 BISNORCHOL 5 EN 22 OXO 22 PIPERIDYLAMINE; METHYLTRANSFERASE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ARTICLE; BIOSYNTHESIS; CHAGAS DISEASE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; LEISHMANIA DONOVANI; LEISHMANIA MAJOR; LEISHMANIASIS; NONHUMAN; PARASITE; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE;

ANIMALS; CELL PROLIFERATION; HUMANS; LEISHMANIA; LIPIDS; METHYLTRANSFERASES; MICE; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA;

LEISHMANIA DONOVANI; LEISHMANIA MAJOR; MAMMALIA; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMA CRUZI;

EID: 23644451158     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.06.012     Document Type: Article

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