Trypanosoma cruzi phosphoenolpyruvate carboxykinase (ATP-dependent): Transition metal ion requirement for activity and sulfhydryl group reactivity

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1292, Issue 1, 1996, Pages 188-196

  Jurado, Luis A ^a   Machín, Ivonne ^a   Urbina, Julio A ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

Activation; Carboxykinase; Phosphoenolpyruvate; Sulfhydryl group reactivity; T. cruzi; Transition metal ion; Trypanosome

Indexed keywords

METAL ION; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); THIOL GROUP; 3 MERCAPTOPICOLINIC ACID; 3-MERCAPTOPICOLINIC ACID; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); ADENOSINE DIPHOSPHATE; CARBON DIOXIDE; CYSTEINE; ENZYME INHIBITOR; MAGNESIUM; MALEIMIDE DERIVATIVE; MANGANESE; METAL; N (7 DIMETHYLAMINO 4 METHYLCOUMARINYL)MALEIMIDE; N-(7-DIMETHYLAMINO-4-METHYLCOUMARINYL)MALEIMIDE; PHOSPHOENOLPYRUVATE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PICOLINIC ACID DERIVATIVE; THIOL DERIVATIVE; THIOL REAGENT;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME MODIFICATION; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; ANIMAL; DRUG ANTAGONISM; ENZYMOLOGY; KINETICS; METABOLISM;

ADENOSINE DIPHOSPHATE; ANIMALS; CARBON DIOXIDE; CYSTEINE; DITHIONITROBENZOIC ACID; ENZYME ACTIVATION; ENZYME INHIBITORS; KINETICS; MAGNESIUM; MALEIMIDES; MANGANESE; METALS; PHOSPHOENOLPYRUVATE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PICOLINIC ACIDS; SULFHYDRYL COMPOUNDS; SULFHYDRYL REAGENTS; TRYPANOSOMA CRUZI;

EID: 0030046836     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4838(95)00201-4     Document Type: Article

References (47)

1. Cazzulo, J.J. (1992) FASEB J. 6, 3152-3161.
2. Urbina, J.A., Machín, I. and Jurado, L. (1993) Biol. Res. 26, 81-88.
3. Urbina, J.A. (1994) Parasitol. Today 10, 107-110.
4. Utter, M.F. and Kolenbrander, H.M. (1972) in The Enzymes (Boyer, P., ed.), 3rd Ed., Vol. 6, pp. 136-154, Academic Press, London.
5. Nowak, T. (1986) in Manganese in Metabolism and Enzyme Function (Schramm, V.L., and Wedler, F.C., eds.), pp. 165-191, Academic Press, London.
6. Schramm, V.L. (1986) in Manganese in Metabolism and Enzyme Function (Schramm, V.L. and Wedler, F.C., eds.), pp. 109-132, Academic Press, London.
7. Mac Grane, M.M., Yub, J.S., Patel, Y.M. and Hanson, R.W. (1992) Trends Biochem. Sci. 17, 40-44.
8. Urbina, J.A. (1987) Arch. Biochem. Biophys. 258, 186-195.
9. Urbina, J.A., Osorno, C.E. and Rojas, A. (1990) Arch. Biochem. Biophys. 282, 91-99.
10. Linss, J., Goldenberg, S., Urbina, J.A. and Amzel, L.M. (1993) Gene 136, 69-77.
11. Colombo, G. and Lardy, H.A. (1981) Biochemistry 20, 2758-2767.
12. Colombo, G. Carlson, G.M. and Lardy, H.A. (1981) Biochemistry 20, 2749-2757.
13. Lee, M.H., Hebda, C.A. and Nowak, T. (1981) J. Biol. Chem. 256, 12793-12801.
14. Schramm, V.L., Fullin, F.A. and Zimmerman, M.D. (1981) J. Biol. Chem. 256, 10803-10808.
15. Hebda, C.A. and Nowak, T. (1982a) J. Biol. Chem. 257, 5503-5514.
16. Lambeth, D.O., Muhonen, W.W., Jacoby, G.H. and Ray, P.D. (1992) Biochim. Biophys. Acta 1156, 85-91.
17. Cannata, J.J.B. and Stoppani, A.O.M. (1963) J. Biol. Chem. 238, 1208-1212.
18. Podkovyrov, S.M. and Zeikus, J.G. (1993) J. Gen. Microbiol. 139, 223-228.
19. Carlson, G.M., Colombo, G. and Lardy, H.A. (1978) Biochemistry 17, 5329-5338.
20. Lewis, C.T., Seyer, J.M. and Carlson, G.M. (1989) J. Biol. Chem. 264, 27-33.
21. Lewis, C.T., Haley, B.E. and Carlson, G.M. (1989) Biochemistry 28, 9248-9255.
22. Lewis, C.T., Seyer, J.M., Cassel, R.G. and Carlson, G.M. (1989) J. Biol. Chem. 268, 1628-1636.
23. Makinen, A.L. and Nowak, T. (1989) J. Biol. Chem. 264, 12148-12157.
24. Chen, C.-Y., Emig, F.A., Schramm, V.L. and ash, D.E. (1991) J. Biol. Chem. 266, 16645-16652.
25. Cardemil, E., Encinas, M.V. and Jabalquinto, A.M. (1990) Biochim. Biophys. Acta 1040, 71-76.
26. Rojas, M.C., Encinas, M.V. and Cardemil, E. (1991) Arch. Biochem. Biophys. 286, 441-447.
27. Rojas, M.C., Encinas, M.V. , Kemp, R.G. Latshaw, S.P. and Cardemil, E. (1993) Biochim. Biophys. Acta 1164, 143-151.
28. Alvear, M., Encinas, M.V., Kemp, R.G. Latshaw, S.P. and Cardemil, E. (1992) Biochim. Biophys. Acta 1119, 35-38.
29. Parsons, M. and Smith, J.M. (1989) Nucleic Acids Res. 17, 6411.
30. De Maio, A. and Urbina, J.A. (1984) Acta Cient. Venez. 35, 136-141.
31. Noce, P.S. and Utter, M.F. (1975) J. Biol. Chem. 260, 9099-9105.
32. Sommer, J.M., Nguyen, T.T. and Wang, C.C. (1994) FEBS Lett. 350, 125-129.
33. Ellman, G.L. (1959) Arch. Biochem. Biophys. 82,70-77.
34. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) J. Biol. Chem. 193, 265-275.
35. Cooper, T.G., Tchen, T.T., Wood, H.G. and Benedict, C.R. (1968) J. Biol. Chem. 243, 3857-3863.
36. Di Tullio, N.W., Berkoff, C.E., Blank, B., Kostos, V., Stack, E.J. and Saunders, H.L. (1974) Biochem. J. 138, 387-394.
37. Jomain-Baum, M., Schramm, V.L. and Hanson, R.W. (1976) J. Biol. Chem. 251, 37-44.
38. Medina, V., Pontarollo, R., Glaeske, D., Tabel, H. and Goldie, H. (1990) J. Gen. Microbiol. 172, 7151-7156.
39. Miller, R.S., Mildvan, A.S., Chang, H.-Ch., Easterday, R.L., Maruyama, H. and Lane, M.D. (1968) J. Biol. Chem. 243, 6030-6040.
40. Hebda, C.A. and Nowak, T. (1982b) J. Biol. Chem. 257, 5515-5522.
41. Lee, M.H. and Nowak, T. (1984) Biochemistry 23, 6506-6513.
42. Duffy, T.H. and Nowak, T. (1985) Biochemistry 24, 1152-1160.
43. Behr, A. (1988) Carbon Dioxide Activation by Metal Complexes, 162 pp., VCH, Weinheim.
44. Walther, D. (1987) Coord. Chem. Rev. 79, 135-174.
45. Braunstein, P., Matt, D. and Nobel, D. (1988) Chem. Rev. 88, 747-764.
46. Hoberg, H., Peres, Y., Krüger, C. and Tsay, Y.-H. (1987) Angew. Chem. 26, 771-773.
47. Nowak, T., Chen, K.-C., Bazaes, S. and Guldinger, P. (1992) FASEB J. 6, A471.