Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 52282-52292

  Park, Kwon Moo ^a,b   Kim, Jee In ^a   Ahn, Youngkeun ^c,e   Bonventre, Andrew J ^a   Bonventre, Joseph V ^a,d,f  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Kyungpook National University School of Medicine   (South Korea)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Chonnam National University Medical School   (South Korea)

^f HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIZATION; BIOCHEMISTRY; CELLS; ENZYMES; NITROGEN COMPOUNDS; PHARMACODYNAMICS; SYNTHESIS (CHEMICAL);

ESTROGEN; ISCHEMIA; NITIC OXIDE SYNTHESIS (NOS); PHOSPHORYLATION;

BIOLOGICAL ORGANS;

ANDROSTANOLONE; ANTIANDROGEN; ANTIESTROGEN; ARGININE DERIVATIVE; ESTROGEN; MITOGEN ACTIVATED PROTEIN KINASE; N NITRO ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TESTOSTERONE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANDROGEN BLOOD LEVEL; AROMATIZATION; ARTICLE; CASTRATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; INFLAMMATION; ISCHEMIA; KIDNEY EPITHELIUM; KIDNEY INJURY; MALE; MOUSE; NONHUMAN; OVARIECTOMY; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREGNANCY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SEX DIFFERENCE;

ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; INTERCELLULAR ADHESION MOLECULE-1; ISCHEMIA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PEROXIDASE; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REPERFUSION INJURY; SEX CHARACTERISTICS; TESTOSTERONE;

EID: 10644228454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407629200     Document Type: Article

References (50)

1. Fukuda, K., Yao, H., Ibayashi, S., Nakahara, T., Uchimura, H., Fujishima, M., and Hall, E. D. (2000) Stroke 31, 155-160
2. Camper-Kirby, D., Welch, S., Walker, A., Shiraishi, I., Setchell, K. D., Schaefer, E., Kajstura, J., Anversa, P., and Sussman, M. A. (2001) Circ. Res. 88, 1020-1027
3. Squadrito, F., Altavilla, D., Squadrito, G., Campo, G. M., Arlotta, M., Arcoraci, V., Minutoli, L., Serrano, M., Saitta, A., and Caputi, A. P. (1997) Eur. J. Pharmacol. 335, 185-192
4. Sugden, P. H., and Clerk, A. (2001) Circ. Res. 88, 975-977
5. Ling, S., Dai, A., Williams, M. R., Myles, K., Dilley, R. J., Komesaroff, P. A., and Sudhir, K. (2002) Endocrinology 143, 1119-1125
6. Muller, V., Losonczy, G., Heemann, U., Vannay, A., Fekete, A., Reusz, G., Tulassay, T., and Szabo, A. J. (2002) Kidney Int. 62, 1364-1371
7. Yang, S. H., Perez, E., Cutright, J., Liu, R., He, Z., Day, A. L., and Simpkins, J. W. (2002) J. Appl. Physiol. 92, 195-201
8. Kelly, K. J., Williams, W. J., Colvin, R. B., Meehan, S. M., Springer, T. A., Gutierrez, R. J., and Bonventre, J. V. (1996) J. Clin. Investig. 97, 1056-1063
9. Sheridan, A. M., and Bonventre, J. V. (2001) Curr. Opin. Nephrol. Hypertens. 9, 427-434
10. Park, K. M., Kramers, C., Vayssier-Taussat, M., Chen, A., and Bonventre, J. V. (2002) J. Biol. Chem. 277, 2040-2049
11. Park, K. M., Chen, A., and Bonventre, J. V. (2001) J. Biol. Chem. 276, 11870-11876
12. Rabb, H., Mendiola, C. C., Saba, S. R., Dietz, J. R., Smith, C. W., Bonventre, J. V., and Ramirez, G. (1995) Biochem. Biophys. Res. Commun. 211, 67-73
13. Park, K. M., Byun, J. Y., Kramers, C., Kim, J. I., Huang, P. L., and Bonventre, J. V. (2003) J. Biol. Chem. 278, 27256-27266
14. Simoncini, T., Hafezi, M. A., Brazil, D. P., Ley, K., Chin, W. W., and Liao, J. K. (2000) Nature 407, 538-541
15. Schramm, L., La, M., Heidbreder, E., Hecker, M., Beckman, J. S., Lopau, K., Zimmermann, J., Rendl, J., Heiners, C., Winderl, S., Wanner, C., and Schmidt, H. H. (2002) Kidney Int. 61, 1423-1432
16. Alexander, B. T., Cockrell, K., Cline, F. D., and Granger, J. P. (2002) Hypertension 39, 586-590
17. Hickey, M. J. (2001) Clin. Sci. (Lond.) 100, 1-12
18. Friedl, R., Brunner, M., Moeslinger, T., and Spieckermann, P. G. (2000) Life Sci. 68, 417-429
19. Neugarten, J., Ding, Q., Friedman, A., Lei, J., and Silbiger, S. (1997) J. Am. Soc. Nephrol. 8, 1240-1246
20. Pasceri, V., Wu, H. D., Willerson, J. T., and Yeh, E. T. (2000) Circulation 101, 235-238
21. Wunderlich, F., Benten, W. P., Lieberherr, M., Guo, Z., Stamm, O., Wrehlke, C., Sekeris, C. E., and Mossmann, H. (2002) Steroids 67, 535-538
22. Guo, Z., Krucken, J., Benten, W. P., and Wunderlich, F. (2002) J. Biol. Chem. 277, 7044-7050
23. Matsui, T., Li, L., del Monte, F., Fukui, Y., Franke, T. F., Hajjar, R. J., and Rosenzweig, A. (1999) Circulation 100, 2373-2379
24. Goligorsky, M.S., Brodsky, S. V., and Noiri, E. (2002) Kidney Int. 61, 855-861
25. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
26. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. (1995) Cell 81, 801-809
27. Hung, C. C., Ichimura, T., Stevens, J. L., and Bonventre, J. V. (2003) J. Biol. Chem. 278, 29317-29326
28. Park, K. M., and Bonventre, J. V. (2000) J. Am. Soc. Nephrol. 11, 594 (abstr.)
29. Rodriguez, E., Lopez, R., Paez, A., Masso, F., and Montano, L. F. (2002) Life Sci. 71, 2181-2193
30. Mori, M., Tsukahara, F., Yoshioka, T., Irie, K., and Ohta, H. (2004) Life Sci. 75, 599-609
31. Alvarez, A., Hermenegildo, C., Issekutz, A. C., Esplugues, J. V., and Sanz, M. J. (2002) Circ. Res. 91, 1142-1150
32. Baker, P., Ramey, E. R., and Ramwell, P. W. (1978) Am. J. Physiol. 235, H242-H246
33. Wakasugi, M., Noguchi, T., Kazama, Y. I., Kanemaru, Y., and Onaya, T. (1989) Prostaglandins 37, 401-410
34. Milewich, L., Chen, G. T., Lyons, C., Tucker, T. F., Uhr, J. W., and MacDonald, P. C. (1982) J. Steroid Biochem. 17, 61-65
35. McCrohon, J. A., Jessup, W., Handelsman, D. J., and Celermajer, D. S. (1999) Circulation 99, 2317-2322
36. McNeill, A. M., Kim, N., Duckles, S. P., Krause, D. N., and Kontos, H. A. (1999) Stroke 30, 2186-2190
37. Vos, I. H., Rabelink, T. J., Dorland, B., Loos, R., Van Middelaar, B., Grone, H. J., and Joles, J. A. (2001) J. Am. Soc. Nephrol. 12, 361-367
38. Ling, H., Edelstein, C., Gengaro, P., Meng, X., Lucia, S., Knotek, M., Wangsiripaisan, A., Shi, Y., and Schrier, R. (1999) Am. J. Physiol. 277, F383-F390
39. Weiner, C. P., Lizasoain, I., Baylis, S. A., Knowles, R. G., Charles, I. G., and Moncada, S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5212-5216
40. Serin, I. S., Kula, M., Basbug, M., Unluhizarci, K., Gucer, S., and Tayyar, M. (2001) Acta Obstet. Gynecol. Scand. 80, 1009-1013
41. Weyrich, A. S., Ma, X. L., and Lefer, A. M. (1992) Circulation 86, 279-288
42. Ha, K., Kim, K., Kwon, Y., Bai, S., Nam, W., Yoo, Y., Kim, P., Chung, H., Billiar, T., and Kim, Y. (2003) FASEB J. 17, 1036-1047
43. Chao, W., Matsui, T., Novikov, M. S., Tao, J., Li, L., Liu, H., Ahn, Y., and Rosenzweig, A. (2003) J. Gene Med. 5, 277-286
44. Hirschberg, R., and Ding, H. (1998) Miner. Electrolyte Metab. 24, 211-219
45. Maestri, M., Dafoe, D. C., Adams, G. A., Gaspari, A., Luzzana, F., Innocente, F., Rademacher, J., Dionigi, P., Barbieri, A., Zonta, F., Zonta, A., and Rabkin, R. (1997) Transplantation 64, 185-190
46. Fernandez, M., Medina, A., Santos, F., Carbajo, E., Rodriguez, J., Alvarez, J., and Cobo, A. (2001) J. Am. Soc. Nephrol. 12, 1900-1907
47. Medina, A., Fernandez-Fuente, M., Carbajo-Perez, E., Santos, F., Amil, B., Rodriguez, J., and Crespo, M. (2002) Pediatr. Nephrol. 17, 1005-1012
48. di Mari, J., Davis, R., and Safirstein, R. L. (1999) Am. J. Physiol. F195-F203
49. Ivanov, V. N., Krasilnikov, M., and Ronai, Z. (2002) J. Biol. Chem. 277, 4932-4944
50. Andreucci, M., Michael, A., Kramers, C., Park, K. M., Chen, A., Matthaeus, T., Alessandrini, A., Haq, S., Force, T., and Bonventre, J. V. (2003) Kidney Int. 64, 1189-1198