Down-regulation of hepatic cytochrome P450 enzymes associated with cisplatin-induced acute renal failure in male rats

Archives of Toxicology

Volumn 80, Issue 6, 2006, Pages 347-353

  Masubuchi, Yasuhiro ^a,b   Kawasaki, Mamiko ^a   Horie, Toshiharu ^a  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA INSTITUTE OF SCIENCE   (Japan)

Author keywords

Acute renal failure; Cisplatin; Hepatic cytochrome; P450; Testosterone

Indexed keywords

CARBOPLATIN; CISPLATIN; CREATININE; CYTOCHROME P450; CYTOCHROME P450 2C11; CYTOCHROME P450 3A2; TESTOSTERONE; UREA;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME IMMUNOASSAY; ENZYME REGULATION; KIDNEY FAILURE; KIDNEY FUNCTION; LIVER FUNCTION; LIVER METABOLISM; LIVER MICROSOME; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TESTIS FUNCTION; TESTOSTERONE BLOOD LEVEL; UREA BLOOD LEVEL; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD UREA NITROGEN; CISPLATIN; CREATININE; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DRUG ANTAGONISM; INJECTIONS, INTRAPERITONEAL; KIDNEY FAILURE; LIVER; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE; THIOUREA;

ANIMALIA;

EID: 33646572246     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0079-z     Document Type: Article

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