γ-H2AX as a therapeutic target for improving the efficacy of radiation therapy

Current Cancer Drug Targets

Volumn 6, Issue 3, 2006, Pages 197-205

  Kao, J ^a,b   Milano, M T ^a   Javaheri, A ^a   Garofalo, M C ^c   Chmura, S J ^a   Weichselbaum, R R ^a   Kron, S J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; DNA damage; H2AX; Radiation; Radiosensitizers

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; CISPLATIN; DOUBLE STRANDED DNA; HISTONE H2AX; MRE11 PROTEIN; NIBRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RAD50 PROTEIN; RADIOSENSITIZING AGENT; SERINE;

CANCER; CANCER RADIOTHERAPY; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOSIMETRY; DRUG TARGETING; ENZYME ACTIVATION; FIBROBLAST; GENOMIC INSTABILITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; KINETICS; OXYGENATION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; RADIOSENSITIVITY; REVIEW; RNA TRANSLATION; SIGNAL TRANSDUCTION; TUMOR CELL; WILD TYPE;

ANTINEOPLASTIC AGENTS; BIOLOGICAL MARKERS; DNA DAMAGE; DNA, NEOPLASM; HISTONES; HUMANS; NEOPLASMS; RADIOTHERAPY;

EID: 33646790488     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800906776842957     Document Type: Review

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