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Volumn 32, Issue 1, 2009, Pages 20-28

Retinoid signals and Th17-mediated pathology

Author keywords

AM80; ATRA; EAE; Foxp3; IL 10; IL 17; Retinoids; ROR t; Th17; Treg

Indexed keywords

11 CIS RETINAL; ALITRETINOIN; BEXAROTENE; CYTOKINE; ETRETIN; ETRETINATE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; ISOTRETINOIN; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID DERIVATIVE; RETINOID X RECEPTOR; RETINOL; TAMIBAROTENE; TAZAROTENE; TRANSCRIPTION FACTOR FOXP3;

EID: 70350766629     PISSN: 09114300     EISSN: 13497413     Source Type: Journal    
DOI: 10.2177/jsci.32.20     Document Type: Review
Times cited : (16)

References (72)
  • 1
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL: TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties, Annu Rev Immunol 7: 145-173, 1989.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 2
    • 0023269443 scopus 로고
    • Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones
    • Cher DJ, Mosmann TR: Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones, J Immunol. 138: 3688-3694, 1987.
    • (1987) J Immunol , vol.138 , pp. 3688-3694
    • Cher, D.J.1    Mosmann, T.R.2
  • 3
    • 1342345214 scopus 로고    scopus 로고
    • The CD4-Th1 model for multiple sclerosis: A critical [correction of crucial] re-appraisal
    • Lassmann H, Ransohoff RM: The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal, Trends Immunol. 25: 132-137, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 132-137
    • Lassmann, H.1    Ransohoff, R.M.2
  • 4
    • 33746729791 scopus 로고    scopus 로고
    • Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
    • Gold R, Linington C, Lassmann H: Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research, Brain 129: 1953-1971, 2006.
    • (2006) Brain , vol.129 , pp. 1953-1971
    • Gold, R.1    Linington, C.2    Lassmann, H.3
  • 5
    • 0036219003 scopus 로고    scopus 로고
    • T cell response in experimental autoimmune encephalomyelitis (EAE): Role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire
    • Kuchroo VK, Anderson AC. Waldner H, Munder M, Bettelli E, Nicholson LB: T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire, Annu Rev Immunol 20: 101-123, 2002.
    • (2002) Annu Rev Immunol , vol.20 , pp. 101-123
    • Kuchroo, V.K.1    Anderson, A.C.2    Waldner, H.3    Munder, M.4    Bettelli, E.5    Nicholson, L.B.6
  • 10
    • 39449110445 scopus 로고    scopus 로고
    • The link between IL-23 and Th17 cell-mediated immune pathologies
    • McGeachy MJ, Cua DJ: The link between IL-23 and Th17 cell-mediated immune pathologies, Semin Immunol 19: 372-376, 2007.
    • (2007) Semin Immunol , vol.19 , pp. 372-376
    • McGeachy, M.J.1    Cua, D.J.2
  • 13
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells, Nature 441: 235-238, 2006.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 17
    • 27544465354 scopus 로고    scopus 로고
    • Rark H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C: A distinct lineagt of CD4 T cells regulates tissue inflammation by producing interleukin 17, Nat Immunol 6: 1133-1141, 2005.
    • Rark H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C: A distinct lineagt of CD4 T cells regulates tissue inflammation by producing interleukin 17, Nat Immunol 6: 1133-1141, 2005.
  • 19
    • 0036188478 scopus 로고    scopus 로고
    • Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein
    • Bush KA, Farmer KM, Walker JS, Kirkham BW: Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein, Arthritis Rheum 46: 802-805, 2002.
    • (2002) Arthritis Rheum , vol.46 , pp. 802-805
    • Bush, K.A.1    Farmer, K.M.2    Walker, J.S.3    Kirkham, B.W.4
  • 20
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S, Nambu A, Sudo K, Iwakura Y: Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice, J Immunol 171: 6173-6177, 2003.
    • (2003) J Immunol , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 21
    • 13244290058 scopus 로고    scopus 로고
    • IL-1 2- and IL-23-induced. T helper cell subsets: Birds of the same feather flock together
    • Bettelli E, Kuchroo VK: IL-1 2- and IL-23-induced. T helper cell subsets: birds of the same feather flock together, J Exp Med. 201: 169-171, 2005.
    • (2005) J Exp Med , vol.201 , pp. 169-171
    • Bettelli, E.1    Kuchroo, V.K.2
  • 22
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL: Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17, J Biol Chem 278: 1910-1914, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    de Sauvage, F.J.4    Gurney, A.L.5
  • 23
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B: TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells, Immunity 24: 179-189, 2006.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 25
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler SF: FOXP3: of mice and men, Annu Rev Immunol. 24: 209-226, 2006.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 26
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory JL-17 + T helper cells
    • Ivanov, II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR: The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory JL-17 + T helper cells, Cell 126: 1121-1133, 2006.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 31
    • 0344389016 scopus 로고    scopus 로고
    • Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
    • Matusevicius D, Kivisakk P, He B, Kostulas N, Ozenci V, Fredrikson S, Link H: Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis, Mult Scler 5: 101-104, 1999.
    • (1999) Mult Scler , vol.5 , pp. 101-104
    • Matusevicius, D.1    Kivisakk, P.2    He, B.3    Kostulas, N.4    Ozenci, V.5    Fredrikson, S.6    Link, H.7
  • 32
    • 38749143286 scopus 로고    scopus 로고
    • Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
    • Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, Fugger L: Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis, Am J Pathol 172: 146-155, 2008.
    • (2008) Am J Pathol , vol.172 , pp. 146-155
    • Tzartos, J.S.1    Friese, M.A.2    Craner, M.J.3    Palace, J.4    Newcombe, J.5    Esiri, M.M.6    Fugger, L.7
  • 33
    • 0031691282 scopus 로고    scopus 로고
    • Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
    • Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD: Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes, J Invest Dermatol 111: 645-649, 1998.
    • (1998) J Invest Dermatol , vol.111 , pp. 645-649
    • Teunissen, M.B.1    Koomen, C.W.2    de Waal Malefyt, R.3    Wierenga, E.A.4    Bos, J.D.5
  • 35
    • 0033083111 scopus 로고    scopus 로고
    • IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells
    • Aarvak T, Chabaud M, Miossec P, Natvig JB: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells, J Immunol 162: 1246-1251, 1999.
    • (1999) J Immunol , vol.162 , pp. 1246-1251
    • Aarvak, T.1    Chabaud, M.2    Miossec, P.3    Natvig, J.B.4
  • 37
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • Chambon P: A decade of molecular biology of retinoic acid receptors, Faseb J 10: 940-954, 1996.
    • (1996) Faseb J , vol.10 , pp. 940-954
    • Chambon, P.1
  • 38
    • 33144488245 scopus 로고    scopus 로고
    • Function of retinoid nuclear receptors: Lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis
    • Mark M, Ghyselinck NB, Chambon P: Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis, Annu Rev Pharmacol Toxicol 46: 451-480, 2006.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 451-480
    • Mark, M.1    Ghyselinck, N.B.2    Chambon, P.3
  • 39
    • 0034938825 scopus 로고    scopus 로고
    • Vitamin A, infection, and immune function
    • Stephensen CB: Vitamin A, infection, and immune function, Annu Rev Nutr 21: 167-192, 2001.
    • (2001) Annu Rev Nutr , vol.21 , pp. 167-192
    • Stephensen, C.B.1
  • 41
    • 0032616999 scopus 로고    scopus 로고
    • Retinoic acid: Its biosynthesis and metabolism
    • Napoli JL: Retinoic acid: its biosynthesis and metabolism, Prog Nucleic Acid Res Mol Biol 63: 139-188, 1999.
    • (1999) Prog Nucleic Acid Res Mol Biol , vol.63 , pp. 139-188
    • Napoli, J.L.1
  • 42
    • 0033911401 scopus 로고    scopus 로고
    • Families of retinoid dehydrogenases regulating vitamin A function: Production of visual pigment and retinoic acid
    • Duester G: Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid, Eur J Biochem 267: 4315-4324, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 4315-4324
    • Duester, G.1
  • 43
    • 0034306499 scopus 로고    scopus 로고
    • Nuclear receptor ligand-binding domains: Three-dimensional structures, molecular interactions and pharmacological implications
    • Bourguet W, Germain P, Gronemeyer H: Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications, Trends Pharmacol Sci 21: 381-388, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 381-388
    • Bourguet, W.1    Germain, P.2    Gronemeyer, H.3
  • 46
    • 0037710726 scopus 로고    scopus 로고
    • Therapy of AIDS-associated Kaposi's sarcoma: Targeting pathogenetic mechanisms
    • Virown SE: Therapy of AIDS-associated Kaposi's sarcoma: targeting pathogenetic mechanisms, Hematol Oncol Clin North Am 17: 763-783, 2003.
    • (2003) Hematol Oncol Clin North Am , vol.17 , pp. 763-783
    • Virown, S.E.1
  • 48
    • 0034980609 scopus 로고    scopus 로고
    • Retinoids for the treatment of psoriasis: Outrook for the future
    • Kuenzli S, Saurat JH: Retinoids for the treatment of psoriasis: outrook for the future, Curr Opin Investig Drugs 2: 6251-630, 2001.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 6251-6630
    • Kuenzli, S.1    Saurat, J.H.2
  • 51
    • 33845876617 scopus 로고    scopus 로고
    • Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis
    • Osanai M, Nishikiori N, Murata M, Chiba H, Kojima T, Sawada N: Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis, Mol Pharmacol 71: 250-258, 2007.
    • (2007) Mol Pharmacol , vol.71 , pp. 250-258
    • Osanai, M.1    Nishikiori, N.2    Murata, M.3    Chiba, H.4    Kojima, T.5    Sawada, N.6
  • 53
    • 34247849185 scopus 로고    scopus 로고
    • Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice
    • Zunino SJ, Storms DH, Stephensen CB: Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice, J Nutr 137: 1216-1221, 2007.
    • (2007) J Nutr , vol.137 , pp. 1216-1221
    • Zunino, S.J.1    Storms, D.H.2    Stephensen, C.B.3
  • 55
    • 0041522463 scopus 로고    scopus 로고
    • Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors
    • Iwata M, Eshima Y, Kagechika H: Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors, Int Immunol 15: 1017-1025, 2003.
    • (2003) Int Immunol , vol.15 , pp. 1017-1025
    • Iwata, M.1    Eshima, Y.2    Kagechika, H.3
  • 56
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T (H) 17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L: A brief history of T (H) 17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage, Nat Med 13: 139-145, 2007.
    • (2007) Nat Med , vol.13 , pp. 139-145
    • Steinman, L.1
  • 57
    • 38949164425 scopus 로고    scopus 로고
    • Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
    • Elias KM, Laurence A, Davidson TS, Stephens G, Kanno Y, Shevach EM, O'Shea JJ: Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway, Blood 111: 1013-1020, 2008.
    • (2008) Blood , vol.111 , pp. 1013-1020
    • Elias, K.M.1    Laurence, A.2    Davidson, T.S.3    Stephens, G.4    Kanno, Y.5    Shevach, E.M.6    O'Shea, J.J.7
  • 59
    • 34548762585 scopus 로고    scopus 로고
    • Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation
    • Schambach F, Schupp M, Lazar MA, Reiner SL: Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation, Eur J Immunol 37: 2396-2399, 2007.
    • (2007) Eur J Immunol , vol.37 , pp. 2396-2399
    • Schambach, F.1    Schupp, M.2    Lazar, M.A.3    Reiner, S.L.4
  • 60
    • 0028876611 scopus 로고
    • Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course
    • Racke MK, Burnett D, Pak SH, Albert PS, Cannella B, Raine CS, McFarlin DE, Scott DE: Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course, J Immunol 154: 450-458, 1995.
    • (1995) J Immunol , vol.154 , pp. 450-458
    • Racke, M.K.1    Burnett, D.2    Pak, S.H.3    Albert, P.S.4    Cannella, B.5    Raine, C.S.6    McFarlin, D.E.7    Scott, D.E.8
  • 61
    • 53149137849 scopus 로고    scopus 로고
    • + regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
    • + regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression, J Immunol 181: 2277-2284, 2008.
    • (2008) J Immunol , vol.181 , pp. 2277-2284
    • Xiao, S.1    Jin, H.2    Korn, T.3    Liu, S.M.4    Oukka, M.5    Lim, B.6    Kuchroo, V.K.7
  • 62
    • 49249139931 scopus 로고    scopus 로고
    • Long-term data in the treatment of psoriasis
    • Thaci D: Long-term data in the treatment of psoriasis, Br J Dermatol 159 Suppl 2: 18-24, 2008.
    • (2008) Br J Dermatol , vol.159 , Issue.SUPPL. 2 , pp. 18-24
    • Thaci, D.1
  • 63
    • 0035167967 scopus 로고    scopus 로고
    • Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, Kelly TE, Saulsbury FT, Chance PF, Ochs HD: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3, Nat Genet 27: 20-21, 2001.
    • Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, Kelly TE, Saulsbury FT, Chance PF, Ochs HD: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3, Nat Genet 27: 20-21, 2001.
  • 66
    • 34547769253 scopus 로고    scopus 로고
    • All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
    • Benson MJ, Pino-Lagos K, Rosemblatt M, Noelle RJ: All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation, J Exp Med 204: 1765-1774, 2007.
    • (2007) J Exp Med , vol.204 , pp. 1765-1774
    • Benson, M.J.1    Pino-Lagos, K.2    Rosemblatt, M.3    Noelle, R.J.4
  • 69
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun CM, Hall JA, Blank RB, Bouladoux N, Oukka M, Mora JR, Belkaid Y: Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid, J Exp Med 204: 1775-1785, 2007.
    • (2007) J Exp Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6    Belkaid, Y.7
  • 72
    • 36248965294 scopus 로고    scopus 로고
    • TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T (H)-17 cell-mediated pathology
    • McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ: TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T (H)-17 cell-mediated pathology, Nat Immunol 8: 1390-1397, 2007.
    • (2007) Nat Immunol , vol.8 , pp. 1390-1397
    • McGeachy, M.J.1    Bak-Jensen, K.S.2    Chen, Y.3    Tato, C.M.4    Blumenschein, W.5    McClanahan, T.6    Cua, D.J.7


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