메뉴 건너뛰기




Volumn 17, Issue 3, 2003, Pages 763-783

Therapy of AIDS-associated Kaposi's sarcoma: Targeting pathogenetic mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

4 DEDIMETHYLAMINOSANCYCLINE; ALITRETINOIN; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; ANGIOSTATIN; BASIC FIBROBLAST GROWTH FACTOR; CYTOKINE; CYTOKINE ANTIBODY; ENDOSTATIN; FUMAGILLOL CHLOROACETYLCARBAMATE; IM 862; INTEGRIN; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 8; ISOTRETINOIN; MARIMASTAT; MATRIX METALLOPROTEINASE INHIBITOR; MONOCLONAL ANTIBODY LM 609; PENTOSAN POLYSULFATE; REBIMASTAT; RECOMBINANT INTERLEUKIN 12; RETINOID; SEMAXANIB; TECOGALAN; THALIDOMIDE; VASCULOTROPIN;

EID: 0037710726     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8588(03)00042-X     Document Type: Review
Times cited : (39)

References (141)
  • 1
    • 0029005449 scopus 로고
    • Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection
    • Moore PS, Chang Y. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N Engl J Med 1995;332:1181-5.
    • (1995) N Engl J Med , vol.332 , pp. 1181-1185
    • Moore, P.S.1    Chang, Y.2
  • 2
    • 0029163617 scopus 로고
    • Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma
    • Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, et al. Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 1995;346:799-802.
    • (1995) Lancet , vol.346 , pp. 799-802
    • Whitby, D.1    Howard, M.R.2    Tenant-Flowers, M.3    Brink, N.S.4    Copas, A.5    Boshoff, C.6
  • 4
    • 0033199819 scopus 로고    scopus 로고
    • Human herpesvirus 8 seropositivity and risk of Kaposi's sarcoma and other acquired immunodeficiency syndrome-related diseases
    • Rezza G, Andreoni M, Dorrucci M, Pezzotti P, Monini P, Zerboni R, et al. Human herpesvirus 8 seropositivity and risk of Kaposi's sarcoma and other acquired immunodeficiency syndrome-related diseases. J Natl Cancer Inst 1999;91:1468-74.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1468-1474
    • Rezza, G.1    Andreoni, M.2    Dorrucci, M.3    Pezzotti, P.4    Monini, P.5    Zerboni, R.6
  • 5
    • 0032564627 scopus 로고    scopus 로고
    • Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi's sarcoma
    • Renwick N, Halaby T, Weverling GJ, Dukers NH, Simpson GR, Coutinho RA, et al. Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi's sarcoma. AIDS 1998;12:2481-8.
    • (1998) AIDS , vol.12 , pp. 2481-2488
    • Renwick, N.1    Halaby, T.2    Weverling, G.J.3    Dukers, N.H.4    Simpson, G.R.5    Coutinho, R.A.6
  • 7
    • 8944226103 scopus 로고    scopus 로고
    • Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma
    • Gao SJ, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, et al. Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med 1996;335:233-41.
    • (1996) N Engl J Med , vol.335 , pp. 233-241
    • Gao, S.J.1    Kingsley, L.2    Hoover, D.R.3    Spira, T.J.4    Rinaldo, C.R.5    Saah, A.6
  • 8
    • 0033199806 scopus 로고    scopus 로고
    • Perspective on Kaposi's sarcoma: Facts, concepts, and conjectures
    • Reitz Jr MS, Nerurkar LS, Gallo RC. Perspective on Kaposi's sarcoma: facts, concepts, and conjectures. J Natl Cancer Inst 1999;91:1453-8.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1453-1458
    • Reitz M.S., Jr.1    Nerurkar, L.S.2    Gallo, R.C.3
  • 10
    • 0037075888 scopus 로고    scopus 로고
    • The molecular pathology of Kaposi's sarcoma-associated herpesvirus
    • Jenner RG, Boshoff C. The molecular pathology of Kaposi's sarcoma-associated herpesvirus. Biochim Biophys Acta 2002;1602:1-22.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 1-22
    • Jenner, R.G.1    Boshoff, C.2
  • 11
    • 0029957833 scopus 로고    scopus 로고
    • Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma
    • Zhong W, Wang H, Herndier B, Ganem D. Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc Natl Acad Sci USA 1996;93: 6641-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6641-6646
    • Zhong, W.1    Wang, H.2    Herndier, B.3    Ganem, D.4
  • 12
    • 0034976535 scopus 로고    scopus 로고
    • Reactivation and role of HHV-8 in Kaposi's sarcoma initiation
    • Ensoli B, Stürzl M, Monini P. Reactivation and role of HHV-8 in Kaposi's sarcoma initiation. Adv Cancer Res 2001;81:161-200.
    • (2001) Adv Cancer Res , vol.81 , pp. 161-200
    • Ensoli, B.1    Stürzl, M.2    Monini, P.3
  • 13
    • 0034973271 scopus 로고    scopus 로고
    • Human herpesvirus-8 and Kaposi's sarcoma: Relationship with the multistep concept of tumorigenesis
    • Stürzl M, Zietz C, Monini P, Ensoli B. Human herpesvirus-8 and Kaposi's sarcoma: relationship with the multistep concept of tumorigenesis. Adv Cancer Res 2001;81:125-59.
    • (2001) Adv Cancer Res , vol.81 , pp. 125-159
    • Stürzl, M.1    Zietz, C.2    Monini, P.3    Ensoli, B.4
  • 14
    • 0030980240 scopus 로고    scopus 로고
    • Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy
    • Kedes DH, Ganem D. Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy. J Clin Invest 1997;99:2082-6.
    • (1997) J Clin Invest , vol.99 , pp. 2082-2086
    • Kedes, D.H.1    Ganem, D.2
  • 15
    • 0029812506 scopus 로고    scopus 로고
    • Anti-herpesvirus treatment and risk of Kaposi's sarcoma in HIV infection
    • Royal Free/Chelsea and Westminster Hospitals Collaborative Group
    • Mocroft A, Youle M, Gazzard B, Morcinek J, Halai R, Phillips AN. Anti-herpesvirus treatment and risk of Kaposi's sarcoma in HIV infection. Royal Free/Chelsea and Westminster Hospitals Collaborative Group. AIDS 1996;10:1101-5.
    • (1996) AIDS , vol.10 , pp. 1101-1105
    • Mocroft, A.1    Youle, M.2    Gazzard, B.3    Morcinek, J.4    Halai, R.5    Phillips, A.N.6
  • 17
    • 0033535532 scopus 로고    scopus 로고
    • Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant
    • Roche Ganciclovir Study Group
    • Martin DF, Kuppermann BD, Wolitz RA, Palestine AG, Li H, Robinson CA. Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. Roche Ganciclovir Study Group. N Engl J Med 1999;340:1063-70.
    • (1999) N Engl J Med , vol.340 , pp. 1063-1070
    • Martin, D.F.1    Kuppermann, B.D.2    Wolitz, R.A.3    Palestine, A.G.4    Li, H.5    Robinson, C.A.6
  • 18
    • 0028598035 scopus 로고
    • Long-term remission of Kaposi's sarcoma following foscamet treatment in HIV-infected patients
    • Morfeldt L, Torssander J. Long-term remission of Kaposi's sarcoma following foscamet treatment in HIV-infected patients. Scand J Infect Dis 1994;26:749-52.
    • (1994) Scand J Infect Dis , vol.26 , pp. 749-752
    • Morfeldt, L.1    Torssander, J.2
  • 19
    • 0032954465 scopus 로고    scopus 로고
    • Effect of antiviral drugs used to treat cytomegalovirus end-organ disease on subsequent course of previously diagnosed Kaposi's sarcoma in patients with AIDS
    • Robles R, Lugo D, Gee L, Jacobson MA. Effect of antiviral drugs used to treat cytomegalovirus end-organ disease on subsequent course of previously diagnosed Kaposi's sarcoma in patients with AIDS. J Acquir Immune Defic Syndr 1999;20:34-8.
    • (1999) J Acquir Immune Defic Syndr , vol.20 , pp. 34-38
    • Robles, R.1    Lugo, D.2    Gee, L.3    Jacobson, M.A.4
  • 20
    • 0028148047 scopus 로고
    • A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections
    • Wagstaff AJ, Bryson HM, Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections. Drugs 1994;48:199-226.
    • (1994) Drugs , vol.48 , pp. 199-226
    • Wagstaff, A.J.1    Bryson, H.M.2    Foscarnet3
  • 21
    • 0034025524 scopus 로고    scopus 로고
    • Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells
    • Shaw RN, Arbiser JL, Offermann MK. Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells. AIDS 2000;14:899-902.
    • (2000) AIDS , vol.14 , pp. 899-902
    • Shaw, R.N.1    Arbiser, J.L.2    Offermann, M.K.3
  • 22
    • 0036057475 scopus 로고    scopus 로고
    • The cell cycle as a target for cancer therapy: Basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01
    • Senderowicz AM. The cell cycle as a target for cancer therapy: basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01. Oncologist 2002;7(Suppl 2):12-9.
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 2 , pp. 12-19
    • Senderowicz, A.M.1
  • 23
    • 0036228709 scopus 로고    scopus 로고
    • Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's sarcoma
    • Barillari G, Ensoli B. Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's sarcoma. Clin Microbiol Rev 2002;15:310-26.
    • (2002) Clin Microbiol Rev , vol.15 , pp. 310-326
    • Barillari, G.1    Ensoli, B.2
  • 24
    • 0027458469 scopus 로고
    • Release, uptake and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, et al. Release, uptake and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 1993;67:277-87.
    • (1993) J Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6
  • 25
    • 0033566297 scopus 로고    scopus 로고
    • The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the α5β1 and αvβ3 integrins and by mobilizing sequestered basic fibroblast growth factor
    • Barillari G, Sgadari C, Fiorelli V, Samaniego F, Colombini S, Manzari V, et al. The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the α5β1 and αvβ3 integrins and by mobilizing sequestered basic fibroblast growth factor. Blood 1999;94:663-72.
    • (1999) Blood , vol.94 , pp. 663-672
    • Barillari, G.1    Sgadari, C.2    Fiorelli, V.3    Samaniego, F.4    Colombini, S.5    Manzari, V.6
  • 26
    • 0033566827 scopus 로고    scopus 로고
    • Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the αvβ3 integrin
    • Barillari G, Sgadari C, Palladino C, Gendelman R, Caputo A, Morris CB, et al. Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the αvβ3 integrin. J Immunol 1999;163:1929-35.
    • (1999) J Immunol , vol.163 , pp. 1929-1935
    • Barillari, G.1    Sgadari, C.2    Palladino, C.3    Gendelman, R.4    Caputo, A.5    Morris, C.B.6
  • 27
    • 0035158524 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor
    • Toschi E, Barillari G, Sgadari C, Bacigalupo I, Cereseto A, Carlei D, et al. Activation of matrix metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor. Mol Biol Cell 2001;12:2934-46.
    • (2001) Mol Biol Cell , vol.12 , pp. 2934-2946
    • Toschi, E.1    Barillari, G.2    Sgadari, C.3    Bacigalupo, I.4    Cereseto, A.5    Carlei, D.6
  • 28
    • 0031572515 scopus 로고    scopus 로고
    • Activation of monocytes by HIV-Tat treatment is mediated by cytokine expression
    • Lafrenie RM, Wahl LM, Epstein JS, Yamada KM, Dhawan S, et al. Activation of monocytes by HIV-Tat treatment is mediated by cytokine expression. J Immunol 1997;159:4077-83.
    • (1997) J Immunol , vol.159 , pp. 4077-4083
    • Lafrenie, R.M.1    Wahl, L.M.2    Epstein, J.S.3    Yamada, K.M.4    Dhawan, S.5
  • 29
    • 0037138427 scopus 로고    scopus 로고
    • HIV-1 infection of primary effusion lymphoma cell line triggers Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation
    • Merat R, Amara A, Lebbe C, de The H, Morel P, Saib A. HIV-1 infection of primary effusion lymphoma cell line triggers Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation. Int J Cancer 2002;97:791-5.
    • (2002) Int J Cancer , vol.97 , pp. 791-795
    • Merat, R.1    Amara, A.2    Lebbe, C.3    De The, H.4    Morel, P.5    Saib, A.6
  • 31
    • 0037067725 scopus 로고    scopus 로고
    • HIV-1-Tat protein activates phosphatidylinositol 3-kinase/AKT-dependent survival pathways in Kaposi's sarcoma cells
    • Deregibus MC, Cantaluppi V, Doublier S, Brizzi MF, Deambrosis I, Albini A, et al. HIV-1-Tat protein activates phosphatidylinositol 3-kinase/AKT-dependent survival pathways in Kaposi's sarcoma cells. J Biol Chem 2002;277:25195-202.
    • (2002) J Biol Chem , vol.277 , pp. 25195-25202
    • Deregibus, M.C.1    Cantaluppi, V.2    Doublier, S.3    Brizzi, M.F.4    Deambrosis, I.5    Albini, A.6
  • 32
    • 0034709659 scopus 로고    scopus 로고
    • Kaposi's sarcoma cells of different etiologic origins respond to HIV-Tat through the Flk-1/KDR (VEGFR-2): Relevance in AIDS-KS pathology
    • Morini M, Benelli R, Giunciuglio D, Carlone S, Arena G, Noonan DM, et al. Kaposi's sarcoma cells of different etiologic origins respond to HIV-Tat through the Flk-1/KDR (VEGFR-2): relevance in AIDS-KS pathology. Biochem Biophys Res Commun 2000;273:267-71.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 267-271
    • Morini, M.1    Benelli, R.2    Giunciuglio, D.3    Carlone, S.4    Arena, G.5    Noonan, D.M.6
  • 33
    • 0034600301 scopus 로고    scopus 로고
    • Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice
    • Prakash O, Tang ZY, He YE, Ali MS, Coleman R, Gill J, et al. Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice. J Natl Cancer Inst 2000;92:721-8.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 721-728
    • Prakash, O.1    Tang, Z.Y.2    He, Y.E.3    Ali, M.S.4    Coleman, R.5    Gill, J.6
  • 34
    • 0032009558 scopus 로고    scopus 로고
    • Kaposi's sarcoma in the Gambia, West Africa is less frequent in human immunodeficiency virus type 2 than in human immunodeficiency virus type 1 infection despite a high prevalence of human herpesvirus 8
    • Ariyoshi K, Schim van der Loeff M, Cook P, Whitby D, Corrah T, Jaffar S, et al. Kaposi's sarcoma in the Gambia, West Africa is less frequent in human immunodeficiency virus type 2 than in human immunodeficiency virus type 1 infection despite a high prevalence of human herpesvirus 8. J Hum Virol 1998;1:193-9.
    • (1998) J Hum Virol , vol.1 , pp. 193-199
    • Ariyoshi, K.1    Schim van der Loeff, M.2    Cook, P.3    Whitby, D.4    Corrah, T.5    Jaffar, S.6
  • 35
    • 0035871694 scopus 로고    scopus 로고
    • Primary human herpesvirus 8 infection generates a broadly specific CD8(+) T-cell response to viral lytic cycle proteins
    • Wang QJ, Jenkins FJ, Jacobson LP, Kingsley LA, Day RD, Zhang ZW, et al. Primary human herpesvirus 8 infection generates a broadly specific CD8(+) T-cell response to viral lytic cycle proteins. Blood 2001;97:2366-73.
    • (2001) Blood , vol.97 , pp. 2366-2373
    • Wang, Q.J.1    Jenkins, F.J.2    Jacobson, L.P.3    Kingsley, L.A.4    Day, R.D.5    Zhang, Z.W.6
  • 36
    • 0036772377 scopus 로고    scopus 로고
    • NK cell activity controls human herpesvirus 8 latent infection and is restored upon highly active antiretroviral therapy in AIDS patients with regressing Kaposi's sarcoma
    • Sirianni MC, Vincenzi L, Topino S, Giovannetti A, Mazzetta F, Libi F, et al. NK cell activity controls human herpesvirus 8 latent infection and is restored upon highly active antiretroviral therapy in AIDS patients with regressing Kaposi's sarcoma. Eur J Immunol 2002;32:2711-20.
    • (2002) Eur J Immunol , vol.32 , pp. 2711-2720
    • Sirianni, M.C.1    Vincenzi, L.2    Topino, S.3    Giovannetti, A.4    Mazzetta, F.5    Libi, F.6
  • 38
    • 0033451961 scopus 로고    scopus 로고
    • Detection of distinct patterns of anti-tat antibodies in HIV-infected individuals with or without Kaposi's sarcoma
    • Emirhan I, Chandra A, Hasselmayer O, Biberfeld P, Chandra P. Detection of distinct patterns of anti-tat antibodies in HIV-infected individuals with or without Kaposi's sarcoma. J Acquir Immune Defic Syndr 1999;22:364-8.
    • (1999) J Acquir Immune Defic Syndr , vol.22 , pp. 364-368
    • Emirhan, I.1    Chandra, A.2    Hasselmayer, O.3    Biberfeld, P.4    Chandra, P.5
  • 39
    • 0033572954 scopus 로고    scopus 로고
    • AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: The Swiss HIV Cohort Study
    • Ledergerber B, Egger M, Erard V, Weber R, Hirschel B, Furrer H, et al. AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study. JAMA 1999;282:2220-6.
    • (1999) JAMA , vol.282 , pp. 2220-2226
    • Ledergerber, B.1    Egger, M.2    Erard, V.3    Weber, R.4    Hirschel, B.5    Furrer, H.6
  • 40
    • 0034232827 scopus 로고    scopus 로고
    • Incidence and trends in Kaposi's sarcoma in the era of effective antiretroviral therapy
    • Jones JL, Hanson DL, Dworkin MS, Jaffe HW. Incidence and trends in Kaposi's sarcoma in the era of effective antiretroviral therapy. J Acquir Immune Defic Syndr 2000;24:270-4.
    • (2000) J Acquir Immune Defic Syndr , vol.24 , pp. 270-274
    • Jones, J.L.1    Hanson, D.L.2    Dworkin, M.S.3    Jaffe, H.W.4
  • 41
    • 0032492955 scopus 로고    scopus 로고
    • Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma
    • Lebbé C, Blum L, Pellet C, Blanchard G, Vérola O, Morel P, et al. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS 1998;12:F45-9.
    • (1998) AIDS , vol.12
    • Lebbé, C.1    Blum, L.2    Pellet, C.3    Blanchard, G.4    Vérola, O.5    Morel, P.6
  • 42
    • 1842638271 scopus 로고    scopus 로고
    • Acquired immunodeficiency syndrome-related Kaposi's sarcoma regression after highly active antiretroviral therapy: Biologic correlates of clinical outcome
    • Cattelan A, Calabro M, Gasperini P, Aversa S, Zanchetta M, Meneghetti F, et al. Acquired immunodeficiency syndrome-related Kaposi's sarcoma regression after highly active antiretroviral therapy: biologic correlates of clinical outcome. J Natl Cancer Inst Monogr 2001;28: 44-9.
    • (2001) J Natl Cancer Inst Monogr , vol.28 , pp. 44-49
    • Cattelan, A.1    Calabro, M.2    Gasperini, P.3    Aversa, S.4    Zanchetta, M.5    Meneghetti, F.6
  • 43
    • 0036184734 scopus 로고    scopus 로고
    • Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy
    • Wilkinson J, Cope A, Gill J, Bourboulia D, Hayes P, Imami N. Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy. J Virol 2002;76:2634-40.
    • (2002) J Virol , vol.76 , pp. 2634-2640
    • Wilkinson, J.1    Cope, A.2    Gill, J.3    Bourboulia, D.4    Hayes, P.5    Imami, N.6
  • 44
    • 0036131462 scopus 로고    scopus 로고
    • HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma
    • Sgadari C, Barillari G, Toschi E, Carlei D, Bacigalupo I, Baccarini S, et al. HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma. Nat Med 2002; 8:225-32.
    • (2002) Nat Med , vol.8 , pp. 225-232
    • Sgadari, C.1    Barillari, G.2    Toschi, E.3    Carlei, D.4    Bacigalupo, I.5    Baccarini, S.6
  • 45
    • 0037093067 scopus 로고    scopus 로고
    • Antitumorigenic effects of HIV protease inhibitor ritonavir: Inhibition of Kaposi's sarcoma
    • Pati S, Pelser CB, Dufraine J, Bryant JL, Reitz Jr MS, Weichold FF. Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi's sarcoma. Blood 2002;99:3771-9.
    • (2002) Blood , vol.99 , pp. 3771-3779
    • Pati, S.1    Pelser, C.B.2    Dufraine, J.3    Bryant, J.L.4    Reitz M.S., Jr.5    Weichold, F.F.6
  • 47
    • 0033564367 scopus 로고    scopus 로고
    • Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma
    • Monini P, Colombini S, Sturzl M, Goletti D, Cafaro A, Sgadari C, et al. Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma. Blood 1999;93:4044-58.
    • (1999) Blood , vol.93 , pp. 4044-4058
    • Monini, P.1    Colombini, S.2    Sturzl, M.3    Goletti, D.4    Cafaro, A.5    Sgadari, C.6
  • 48
    • 0034606671 scopus 로고    scopus 로고
    • Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication
    • Chang J, Renne R, Dittmer D, Ganem D. Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication. Virology 2000;266:17-25.
    • (2000) Virology , vol.266 , pp. 17-25
    • Chang, J.1    Renne, R.2    Dittmer, D.3    Ganem, D.4
  • 49
    • 0028091495 scopus 로고
    • Expression of adhesion molecules, platelet activating factor and chemokines by Kaposi's sarcoma cells
    • Sciacca FL, Sturzl M, Bussolino F, Sironi M, Brandstetter H, Zietz C, et al. Expression of adhesion molecules, platelet activating factor and chemokines by Kaposi's sarcoma cells. J Immunol 1994;153:4816-25.
    • (1994) J Immunol , vol.153 , pp. 4816-4825
    • Sciacca, F.L.1    Sturzl, M.2    Bussolino, F.3    Sironi, M.4    Brandstetter, H.5    Zietz, C.6
  • 50
    • 0028947198 scopus 로고
    • Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells
    • Fiorelli V, Gendelman R, Samaniego F, Markham PD, Ensoli B. Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells. J Clin Invest 1995;95:1723-34.
    • (1995) J Clin Invest , vol.95 , pp. 1723-1734
    • Fiorelli, V.1    Gendelman, R.2    Samaniego, F.3    Markham, P.D.4    Ensoli, B.5
  • 51
    • 0033555401 scopus 로고    scopus 로고
    • IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: Implications for AIDS-Kaposi's sarcoma pathogenesis
    • Fiorelli V, Barillari G, Toschi E, Sgadari C, Monini P, Sturzl M, et al. IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis. J Immunol 1999;162: 1165-70.
    • (1999) J Immunol , vol.162 , pp. 1165-1170
    • Fiorelli, V.1    Barillari, G.2    Toschi, E.3    Sgadari, C.4    Monini, P.5    Sturzl, M.6
  • 52
    • 0028969818 scopus 로고
    • Inflammatory cytokines induce AIDS-Kaposi's sarcoma (KS)-derived spindle cells to produce and release basic fibroblast growth factor and enhance KS-like lesion formation in nude mice
    • Samaniego F, Markham PD, Gallo RC, Ensoli B. Inflammatory cytokines induce AIDS-Kaposi's sarcoma (KS)-derived spindle cells to produce and release basic fibroblast growth factor and enhance KS-like lesion formation in nude mice. J Immunol 1995;154:3582-92.
    • (1995) J Immunol , vol.154 , pp. 3582-3592
    • Samaniego, F.1    Markham, P.D.2    Gallo, R.C.3    Ensoli, B.4
  • 53
    • 0031568523 scopus 로고    scopus 로고
    • Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice
    • Samaniego F, Markham PD, Gendelman R, Gallo RC, Ensoli B. Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice. J Immunol 1997;158:1887-94.
    • (1997) J Immunol , vol.158 , pp. 1887-1894
    • Samaniego, F.1    Markham, P.D.2    Gendelman, R.3    Gallo, R.C.4    Ensoli, B.5
  • 56
    • 0024579609 scopus 로고
    • AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects
    • Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, et al. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science 1989;243:223-6.
    • (1989) Science , vol.243 , pp. 223-226
    • Ensoli, B.1    Nakamura, S.2    Salahuddin, S.Z.3    Biberfeld, P.4    Larsson, L.5    Beaver, B.6
  • 57
    • 0024359975 scopus 로고
    • Purification and characterization of cytokine-induced neutrophil chemoattractant produced by epithelioid cell line of normal rat kidney (NRK-52E cell)
    • Watanabe K, Kinoshita S, Nakagawa H. Purification and characterization of cytokine-induced neutrophil chemoattractant produced by epithelioid cell line of normal rat kidney (NRK-52E cell). Biochem Biophys Res Commun 1989;161:1093-9.
    • (1989) Biochem Biophys Res Commun , vol.161 , pp. 1093-1099
    • Watanabe, K.1    Kinoshita, S.2    Nakagawa, H.3
  • 59
    • 0034808316 scopus 로고    scopus 로고
    • Interleukin 8 is an autocrine growth factor and a surrogate marker for Kaposi's sarcoma
    • Masood R, Cai J, Tulpule A, Zheng T, Hamilton A, Sharma S, et al. Interleukin 8 is an autocrine growth factor and a surrogate marker for Kaposi's sarcoma. Clin Cancer Res 2001;7:2693-702.
    • (2001) Clin Cancer Res , vol.7 , pp. 2693-2702
    • Masood, R.1    Cai, J.2    Tulpule, A.3    Zheng, T.4    Hamilton, A.5    Sharma, S.6
  • 60
    • 0032532063 scopus 로고    scopus 로고
    • Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture
    • Gershengorn MC, Geras-Raaka E, Varma A, Clark-Lewis I. Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture. J Clin Investig 1998;102:1469-72.
    • (1998) J Clin Investig , vol.102 , pp. 1469-1472
    • Gershengorn, M.C.1    Geras-Raaka, E.2    Varma, A.3    Clark-Lewis, I.4
  • 61
    • 0024565271 scopus 로고
    • Intravenous recombinant tumor necrosis factor in the treatment of AIDS-related Kaposi's sarcoma
    • Aboulafia D, Miles SA, Saks SR, Mitsuyasu RT. Intravenous recombinant tumor necrosis factor in the treatment of AIDS-related Kaposi's sarcoma. J Acquir Immune Defic Syndr 1989; 2:54-8.
    • (1989) J Acquir Immune Defic Syndr , vol.2 , pp. 54-58
    • Aboulafia, D.1    Miles, S.A.2    Saks, S.R.3    Mitsuyasu, R.T.4
  • 62
    • 0024323943 scopus 로고
    • Exacerbation of epidemic Kaposi's sarcoma with a combination of interleukin-2 and γ interferon: Results of a phase 2 study
    • Krigel RL, Padavic-Shaller KA, Rudolph AR, Poiesz BJ, Comis RL. Exacerbation of epidemic Kaposi's sarcoma with a combination of interleukin-2 and γ interferon: results of a phase 2 study. J Biol Response Mod 1989;8:359-65.
    • (1989) J Biol Response Mod , vol.8 , pp. 359-365
    • Krigel, R.L.1    Padavic-Shaller, K.A.2    Rudolph, A.R.3    Poiesz, B.J.4    Comis, R.L.5
  • 63
    • 0027172443 scopus 로고
    • Clinical aspects of AIDS-related Kaposi's sarcoma
    • Mitsuyasu RT. Clinical aspects of AIDS-related Kaposi's sarcoma. Curr Opin Oncol 1993;5: 835-44.
    • (1993) Curr Opin Oncol , vol.5 , pp. 835-844
    • Mitsuyasu, R.T.1
  • 64
  • 65
    • 0028344128 scopus 로고
    • Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells
    • Corbeil J, Rappaport E, Richman DD, Looney DJ. Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells. J Clin Invest 1994;93:1981-6.
    • (1994) J Clin Invest , vol.93 , pp. 1981-1986
    • Corbeil, J.1    Rappaport, E.2    Richman, D.D.3    Looney, D.J.4
  • 66
    • 0028854198 scopus 로고
    • Inhibition of AIDS-Kaposi's sarcoma cell proliferation following retinoic acid receptor activation
    • Guo WX, Gill PS, Antakly T. Inhibition of AIDS-Kaposi's sarcoma cell proliferation following retinoic acid receptor activation. Cancer Res 1995;55:823-9.
    • (1995) Cancer Res , vol.55 , pp. 823-829
    • Guo, W.X.1    Gill, P.S.2    Antakly, T.3
  • 67
    • 0028151338 scopus 로고
    • Inhibitory effect of all-trans retinoic acid on the growth of freshly isolated myeloma cells via interference with interleukin-6 signal transduction
    • Ogata A, Nishimoto N, Shima Y, Yoshizaki K, Kishimoto T. Inhibitory effect of all-trans retinoic acid on the growth of freshly isolated myeloma cells via interference with interleukin-6 signal transduction. Blood 1994;84:3040-6.
    • (1994) Blood , vol.84 , pp. 3040-3046
    • Ogata, A.1    Nishimoto, N.2    Shima, Y.3    Yoshizaki, K.4    Kishimoto, T.5
  • 68
    • 0035260470 scopus 로고    scopus 로고
    • Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway
    • Tsang KJ, Crowe DL. Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway. Int J Oncol 2001;18:369-74.
    • (2001) Int J Oncol , vol.18 , pp. 369-374
    • Tsang, K.J.1    Crowe, D.L.2
  • 69
    • 0029163513 scopus 로고
    • Phase I/II study of intermittent all-trans-retinoic acid, alone and in combination with interferon alfa-2a, in patients with epidemic Kaposi's sarcoma
    • Bailey J, Pluda JM, Foli A, Saville MW, Bauza S, Adamson PC, et al. Phase I/II study of intermittent all-trans-retinoic acid, alone and in combination with interferon alfa-2a, in patients with epidemic Kaposi's sarcoma. J Clin Oncol 1995;13:1966-74.
    • (1995) J Clin Oncol , vol.13 , pp. 1966-1974
    • Bailey, J.1    Pluda, J.M.2    Foli, A.3    Saville, M.W.4    Bauza, S.5    Adamson, P.C.6
  • 70
    • 0028588121 scopus 로고
    • All-trans retinoic acid for the treatment of AIDS-related Kaposi's sarcoma: Results of a pilot phase II study
    • Gill PS, Espina BM, Moudgil T, Kidane S, Esplin JA, Tulpule A, et al. All-trans retinoic acid for the treatment of AIDS-related Kaposi's sarcoma: results of a pilot phase II study. Leukemia 1994;8(Suppl 3):S26-32.
    • (1994) Leukemia , vol.8 , Issue.SUPPL. 3
    • Gill, P.S.1    Espina, B.M.2    Moudgil, T.3    Kidane, S.4    Esplin, J.A.5    Tulpule, A.6
  • 71
    • 0032511918 scopus 로고    scopus 로고
    • Treatment of early AIDS-related Kaposi's sarcoma with oral all-trans-retinoic acid: Results of a sequential non-randomized phase II trial
    • Saiag P, Pavlovic M, Clerici T, Feauveau V, Nicolas J-C, Emilie D, et al. Treatment of early AIDS-related Kaposi's sarcoma with oral all-trans-retinoic acid: results of a sequential non-randomized phase II trial. AIDS 1998;12:2169-76.
    • (1998) AIDS , vol.12 , pp. 2169-2176
    • Saiag, P.1    Pavlovic, M.2    Clerici, T.3    Feauveau, V.4    Nicolas, J.-C.5    Emilie, D.6
  • 73
    • 0033401401 scopus 로고    scopus 로고
    • Treatment of AIDS-related cutaneous Kaposi's sarcoma with topical alitretinoin (9-cis-retinoic acid) gel
    • Panretin Gel North American Study Group
    • Walmsley S, Northfelt DW, Melosky B, Conant M, Friedman-Kien AE, Wagner B. Treatment of AIDS-related cutaneous Kaposi's sarcoma with topical alitretinoin (9-cis-retinoic acid) gel. Panretin Gel North American Study Group. J Acquir Immune Defic Syndr 1999;22:235-46.
    • (1999) J Acquir Immune Defic Syndr , vol.22 , pp. 235-246
    • Walmsley, S.1    Northfelt, D.W.2    Melosky, B.3    Conant, M.4    Friedman-Kien, A.E.5    Wagner, B.6
  • 74
    • 0037083808 scopus 로고    scopus 로고
    • Antitumor activity of oral 9-cis-retinoic acid in HIV-associated Kaposi's sarcoma
    • Miles SA, Dezube BJ, Lee JY, Krown SE, Fletcher MA, Saville MW, et al. Antitumor activity of oral 9-cis-retinoic acid in HIV-associated Kaposi's sarcoma. AIDS 2002;16:421-9.
    • (2002) AIDS , vol.16 , pp. 421-429
    • Miles, S.A.1    Dezube, B.J.2    Lee, J.Y.3    Krown, S.E.4    Fletcher, M.A.5    Saville, M.W.6
  • 75
    • 0030979018 scopus 로고    scopus 로고
    • Interleukin 6 and AIDS associated Kaposi's sarcoma: A nested case control study within the Multicenter AIDS Cohort Study
    • Dourado I, Martinez-Maza O, Kishimoto T, Suzuki H, Detels R. Interleukin 6 and AIDS associated Kaposi's sarcoma: a nested case control study within the Multicenter AIDS Cohort Study. AIDS Res Hum Retroviruses 1997;13:781-8.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 781-788
    • Dourado, I.1    Martinez-Maza, O.2    Kishimoto, T.3    Suzuki, H.4    Detels, R.5
  • 76
    • 0034872059 scopus 로고    scopus 로고
    • Treatment of Kaposi's sarcoma: The role of interferon and thalidomide
    • Krown SE. Treatment of Kaposi's sarcoma: the role of interferon and thalidomide. Curr Opin Oncol 2001;13:374-81.
    • (2001) Curr Opin Oncol , vol.13 , pp. 374-381
    • Krown, S.E.1
  • 81
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8 + subset
    • Haslett PAJ, Corral LG, Albert M, Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8 + subset. J Exp Med 1998;187:1885-92.
    • (1998) J Exp Med , vol.187 , pp. 1885-1892
    • Haslett, P.A.J.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 82
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogs which are potent inhibitors of TNF-α
    • Corral LG, Haslett PAJ, Muller GW, Chen R, Wong LM, Ocampo CJ, et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogs which are potent inhibitors of TNF-α. J Immunol 1999;163:380-96.
    • (1999) J Immunol , vol.163 , pp. 380-396
    • Corral, L.G.1    Haslett, P.A.J.2    Muller, G.W.3    Chen, R.4    Wong, L.M.5    Ocampo, C.J.6
  • 84
    • 0031675320 scopus 로고    scopus 로고
    • Activity of thalidomide in AIDS-related Kaposi's sarcoma and correlation with HHV8 titre
    • Fife K, Howard MR, Gracie F, Phillips RH, Bower M. Activity of thalidomide in AIDS-related Kaposi's sarcoma and correlation with HHV8 titre. Int J STD AIDS 1998;9:751-5.
    • (1998) Int J STD AIDS , vol.9 , pp. 751-755
    • Fife, K.1    Howard, M.R.2    Gracie, F.3    Phillips, R.H.4    Bower, M.5
  • 87
    • 0029922177 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
    • Sgadari C, Angiolillo AL, Tosato G. Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 1996;87:3877-82.
    • (1996) Blood , vol.87 , pp. 3877-3882
    • Sgadari, C.1    Angiolillo, A.L.2    Tosato, G.3
  • 88
    • 0033104852 scopus 로고    scopus 로고
    • Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12
    • Yao L, Sgadari C, Furuke K, Bloom ET, Teruya-Feldstein J, Tosato G. Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12. Blood 1999;93:1612-21.
    • (1999) Blood , vol.93 , pp. 1612-1621
    • Yao, L.1    Sgadari, C.2    Furuke, K.3    Bloom, E.T.4    Teruya-Feldstein, J.5    Tosato, G.6
  • 89
    • 0031823574 scopus 로고    scopus 로고
    • Human interferon-γ-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
    • Geras-Raaka E, Varma A, Ho H, Gershengorn MC. Human interferon-γ-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. J Exp Med 1998;188:405-8.
    • (1998) J Exp Med , vol.188 , pp. 405-408
    • Geras-Raaka, E.1    Varma, A.2    Ho, H.3    Gershengorn, M.C.4
  • 90
    • 85031145420 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) appears to be active in AIDS-asociated Kaposi's sarcoma (KS): Early results of a pilot study
    • Paper presented. San Francisco, January 30-February 2 [abstract #5]
    • Little RF, Pluda JM, Wyvill K, Lietzau J, Shearer G, Tosato G, et al. Interleukin 12 (IL-12) appears to be active in AIDS-asociated Kaposi's sarcoma (KS): early results of a pilot study. Paper presented at the 7th Conference on Retroviruses and Opportunistic Infections [abstract #5]. San Francisco, January 30-February 2, 2000.
    • (2000) 7th Conference on Retroviruses and Opportunistic Infections
    • Little, R.F.1    Pluda, J.M.2    Wyvill, K.3    Lietzau, J.4    Shearer, G.5    Tosato, G.6
  • 91
    • 0035819527 scopus 로고    scopus 로고
    • Development of matrix metalloproteinase inhibitors in cancer therapy
    • Hidalgo M, Eckhardt SG. Development of matrix metalloproteinase inhibitors in cancer therapy. J Natl Cancer Inst 2001;93:178-93.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 178-193
    • Hidalgo, M.1    Eckhardt, S.G.2
  • 92
    • 0033134622 scopus 로고    scopus 로고
    • Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
    • Stetler-Stevenson WG. Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention. J Clin Invest 1999;103:1237-41.
    • (1999) J Clin Invest , vol.103 , pp. 1237-1241
    • Stetler-Stevenson, W.G.1
  • 93
    • 0034866222 scopus 로고    scopus 로고
    • Matrix metalloproteinases as targets for therapy in Kaposi's sarcoma
    • Fingleton B, Matrisian LM. Matrix metalloproteinases as targets for therapy in Kaposi's sarcoma. Curr Opin Oncol 2001;13:368-73.
    • (2001) Curr Opin Oncol , vol.13 , pp. 368-373
    • Fingleton, B.1    Matrisian, L.M.2
  • 94
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
    • Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2000; 2:737-44.
    • (2000) Nat Cell Biol , vol.2 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3    Vu, T.H.4    Itoh, T.5    Tamaki, K.6
  • 95
    • 0032801307 scopus 로고    scopus 로고
    • Expression of multiple matrix metalloproteinases and urokinase type plasminogen activator in cultured Kaposi sarcoma cells
    • Meade-Tolin LC, Way D, Witte MH. Expression of multiple matrix metalloproteinases and urokinase type plasminogen activator in cultured Kaposi sarcoma cells. Acta Histochem 1999; 101:305-16.
    • (1999) Acta Histochem , vol.101 , pp. 305-316
    • Meade-Tolin, L.C.1    Way, D.2    Witte, M.H.3
  • 96
    • 0027981273 scopus 로고
    • Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: Inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2
    • Albini A, Fontanini G, Masiello L, Tacchetti C, Bigini D, Luzzi P, et al. Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2. AIDS 1994;8:1237-44.
    • (1994) AIDS , vol.8 , pp. 1237-1244
    • Albini, A.1    Fontanini, G.2    Masiello, L.3    Tacchetti, C.4    Bigini, D.5    Luzzi, P.6
  • 97
    • 0031870786 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro
    • Lamoreaux WJ, Fitzgerald MEC, Reiner A, Hasty KA, Charles ST. Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro. Microvasc Res 1998;55:29-42.
    • (1998) Microvasc Res , vol.55 , pp. 29-42
    • Lamoreaux, W.J.1    Fitzgerald, M.E.C.2    Reiner, A.3    Hasty, K.A.4    Charles, S.T.5
  • 98
    • 0036137547 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: A phase I AIDS Malignancy Consortium study
    • Cianfrocca M, Cooley TP, Lee JY, Rudeck MA, Ratner L, Pluda JM, et al. Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS Malignancy Consortium study. J Clin Oncol 2002;20:153-9.
    • (2002) J Clin Oncol , vol.20 , pp. 153-159
    • Cianfrocca, M.1    Cooley, T.P.2    Lee, J.Y.3    Rudeck, M.A.4    Ratner, L.5    Pluda, J.M.6
  • 100
    • 0027220944 scopus 로고
    • The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi's sarcoma and cytokine activated vascular cells induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence
    • Barillari G, Gendelman R, Gallo RC, Ensoli B. The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi's sarcoma and cytokine activated vascular cells induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc Natl Acad Sci USA 1993;90:7941-5.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7941-7945
    • Barillari, G.1    Gendelman, R.2    Gallo, R.C.3    Ensoli, B.4
  • 103
    • 0031017221 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor is an autocrine factor for AIDS-Kaposi's sarcoma
    • Masood R, Cai J, Zheng T, Smith DL, Naidu Y, Gill PS. Vascular endothelial growth factor/ vascular permeability factor is an autocrine factor for AIDS-Kaposi's sarcoma. Proc Natl Acad Sci USA 1997;94:979-84.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 979-984
    • Masood, R.1    Cai, J.2    Zheng, T.3    Smith, D.L.4    Naidu, Y.5    Gill, P.S.6
  • 104
    • 0031569950 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is a potent angiogenic factor in AIDS-associated Kaposi's sarcoma-derived spindle cells
    • Nakamura S, Murakami-Mori K, Rao N, Weich H, Rajeev B. Vascular endothelial growth factor is a potent angiogenic factor in AIDS-associated Kaposi's sarcoma-derived spindle cells. J Immunol 1997;158:4992-5001.
    • (1997) J Immunol , vol.158 , pp. 4992-5001
    • Nakamura, S.1    Murakami-Mori, K.2    Rao, N.3    Weich, H.4    Rajeev, B.5
  • 105
    • 0029847089 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma
    • Comali E, Zietz C, Benelli R, Weninger W, Masiello L, Breier G, et al. Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma. Am J Pathol 1996;149:1851-69.
    • (1996) Am J Pathol , vol.149 , pp. 1851-1869
    • Comali, E.1    Zietz, C.2    Benelli, R.3    Weninger, W.4    Masiello, L.5    Breier, G.6
  • 106
    • 0029993747 scopus 로고    scopus 로고
    • Strong expression of kinase insert domain containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma
    • Brown LF, Tognazzi K, Dvorak HF, Harrist TJ. Strong expression of kinase insert domain containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma. Am J Pathol 1996;148: 1065-74.
    • (1996) Am J Pathol , vol.148 , pp. 1065-1074
    • Brown, L.F.1    Tognazzi, K.2    Dvorak, H.F.3    Harrist, T.J.4
  • 107
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong TA, Shawver LK, Sun L, Tang C, App H, Powell TJ, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999;59:99-106.
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.A.1    Shawver, L.K.2    Sun, L.3    Tang, C.4    App, H.5    Powell, T.J.6
  • 108
    • 0034003716 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor (VEGF) in AIDS-related Kaposi's sarcoma
    • Arasteh K, Hannah A. The role of vascular endothelial growth factor (VEGF) in AIDS-related Kaposi's sarcoma. Oncologist 2000;5(Suppl 1):28-31.
    • (2000) Oncologist , vol.5 , Issue.SUPPL. 1 , pp. 28-31
    • Arasteh, K.1    Hannah, A.2
  • 109
    • 0026032034 scopus 로고
    • Fibroblast growth factor gene expression in AUDS-Kaposi's sarcoma detected by in situ hybridization
    • Xerri L, Houssoun J, Planche J, Guigou V, Grob JJ, Parc P, et al. Fibroblast growth factor gene expression in AUDS-Kaposi's sarcoma detected by in situ hybridization. Am J Pathol 1991;138: 9-15.
    • (1991) Am J Pathol , vol.138 , pp. 9-15
    • Xerri, L.1    Houssoun, J.2    Planche, J.3    Guigou, V.4    Grob, J.J.5    Parc, P.6
  • 110
    • 18244420373 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development
    • Samaniego F, Markham PD, Gendelman R, Watanabe Y, Kao V, Kowalski K, et al. Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development. Am J Pathol 1998;152:1433-43.
    • (1998) Am J Pathol , vol.152 , pp. 1433-1443
    • Samaniego, F.1    Markham, P.D.2    Gendelman, R.3    Watanabe, Y.4    Kao, V.5    Kowalski, K.6
  • 111
    • 0028075875 scopus 로고
    • Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS
    • Ensoli B, Markham P, Kao V, Barillari G, Fiorelli V, Gendelman R, et al. Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS. J Clin Invest 1994;94:1736-46.
    • (1994) J Clin Invest , vol.94 , pp. 1736-1746
    • Ensoli, B.1    Markham, P.2    Kao, V.3    Barillari, G.4    Fiorelli, V.5    Gendelman, R.6
  • 112
    • 0027435129 scopus 로고
    • Administration of pentosan polysulfate to patients with human immunodeficiency virus-associated Kaposi's sarcoma
    • Pluda JM, Shay LE, Foli A, Tannenbaum S, Cohen PJ, Goldspiel BR, et al. Administration of pentosan polysulfate to patients with human immunodeficiency virus-associated Kaposi's sarcoma. J Natl Cancer Inst 1993;85:1585-92.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1585-1592
    • Pluda, J.M.1    Shay, L.E.2    Foli, A.3    Tannenbaum, S.4    Cohen, P.J.5    Goldspiel, B.R.6
  • 113
    • 0003310680 scopus 로고
    • A Phase I study of tecogalan, a novel angiogenesis inhibitor in the treatment of AIDS-related Kaposi's sarcoma and solid tumors
    • Tulpule A, Snyder JC, Espina BM, Higashi L, Satomi M, Lombardy EE, et al. A Phase I study of tecogalan, a novel angiogenesis inhibitor in the treatment of AIDS-related Kaposi's sarcoma and solid tumors [abstract]. Blood 1994;84(10, Suppl 1):248a.
    • (1994) Blood , vol.84 , Issue.10 SUPPL. 1
    • Tulpule, A.1    Snyder, J.C.2    Espina, B.M.3    Higashi, L.4    Satomi, M.5    Lombardy, E.E.6
  • 114
    • 0029075603 scopus 로고
    • Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas
    • Singh RK, Gutman M, Bucana CD, Sanchez R, Llansa N, Fidler IJ. Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci USA 1995;92:4562-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4562-4566
    • Singh, R.K.1    Gutman, M.2    Bucana, C.D.3    Sanchez, R.4    Llansa, N.5    Fidler, I.J.6
  • 115
    • 2642708372 scopus 로고    scopus 로고
    • Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization
    • Perollet C, Han ZC, Savona C, Caen JP, Bikfalvi A. Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization. Blood 1998;91:3289-99.
    • (1998) Blood , vol.91 , pp. 3289-3299
    • Perollet, C.1    Han, Z.C.2    Savona, C.3    Caen, J.P.4    Bikfalvi, A.5
  • 116
    • 0010550864 scopus 로고
    • A randomized dose finding study of recombinant platelet factor 4 (rPF4) in cutaneous AIDS-related Kaposi's sarcoma (KS)
    • Staddon A, Henry D, Bonnem E. A randomized dose finding study of recombinant platelet factor 4 (rPF4) in cutaneous AIDS-related Kaposi's sarcoma (KS) [abstract]. Proc Am Soc Clin Oncol 1994;13:A3.
    • (1994) Proc Am Soc Clin Oncol , vol.13
    • Staddon, A.1    Henry, D.2    Bonnem, E.3
  • 117
    • 0038403128 scopus 로고
    • Phase I/II study of IV recombinant platelet factor 4 (rPF4) in AIDS-related Kaposi's sarcoma (AIDS-KS)
    • Northfelt DW, Robles R, Lang W, Wagner B, Kahn J, Bonnem E. Phase I/II study of IV recombinant platelet factor 4 (rPF4) in AIDS-related Kaposi's sarcoma (AIDS-KS) [abstract]. Proc Am Soc Clin Oncol 1995;14:820.
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 820
    • Northfelt, D.W.1    Robles, R.2    Lang, W.3    Wagner, B.4    Kahn, J.5    Bonnem, E.6
  • 118
    • 0035929606 scopus 로고    scopus 로고
    • Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity
    • Lozano RM, Redondo-Horcajo M, Jimenez MA, Zilberberg L, Cuevas P, Bikfalvi A, et al. Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity. J Biol Chem 2001;276:35723-34.
    • (2001) J Biol Chem , vol.276 , pp. 35723-35734
    • Lozano, R.M.1    Redondo-Horcajo, M.2    Jimenez, M.A.3    Zilberberg, L.4    Cuevas, P.5    Bikfalvi, A.6
  • 119
  • 120
    • 0030924753 scopus 로고    scopus 로고
    • The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
    • Sin N, Meng L, Wang MQ, Wen JJ, Bommann WG, Crews CM. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc Natl Acad Sci USA 1997;94:6099-103.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6099-6103
    • Sin, N.1    Meng, L.2    Wang, M.Q.3    Wen, J.J.4    Bommann, W.G.5    Crews, C.M.6
  • 121
    • 0034612236 scopus 로고    scopus 로고
    • Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1
    • Zhang Y, Griffith EC, Sage J, Jacks T, Liu JO. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proc Natl Acad Sci USA 2000;97:6427-32.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6427-6432
    • Zhang, Y.1    Griffith, E.C.2    Sage, J.3    Jacks, T.4    Liu, J.O.5
  • 122
    • 0031897809 scopus 로고    scopus 로고
    • Fumagillin analog in the treatment of Kaposi's sarcoma: A phase I AIDS Clinical Trial Group study
    • AIDS Clinical Trial Group No. 215 Team
    • Dezube BJ, VonRoenn JH, Holden Wiltse J, Cheung TW, Remick SC, Cooley TP, et al. Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team. J Clin Oncol 1998;16:1444-9.
    • (1998) J Clin Oncol , vol.16 , pp. 1444-1449
    • Dezube, B.J.1    VonRoenn, J.H.2    Holden Wiltse, J.3    Cheung, T.W.4    Remick, S.C.5    Cooley, T.P.6
  • 124
    • 0037008721 scopus 로고    scopus 로고
    • Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1
    • Kim YM, Hwang S, Kim YM, Pyun BJ, Kim TY, Lee ST, et al. Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J Biol Chem 2002;277:27872-9.
    • (2002) J Biol Chem , vol.277 , pp. 27872-27879
    • Kim, Y.M.1    Hwang, S.2    Kim, Y.M.3    Pyun, B.J.4    Kim, T.Y.5    Lee, S.T.6
  • 125
    • 0036831302 scopus 로고    scopus 로고
    • The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells
    • Hajitou A, Grignet-Debrus C, Devy L, Berndt S, Blacher S, Deroanne CF, et al. The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells. FASEB J 2002;16:1802-4.
    • (2002) FASEB J , vol.16 , pp. 1802-1804
    • Hajitou, A.1    Grignet-Debrus, C.2    Devy, L.3    Berndt, S.4    Blacher, S.5    Deroanne, C.F.6
  • 126
    • 0034307327 scopus 로고    scopus 로고
    • Endostatin inhibits endothelial and tumor cell invasion by blocking the activation and catalytic activity of matrix metalloproteinase
    • Kim YM, Jang JW, Lee OH, Yeon J, Choi EY, Kim KW, et al. Endostatin inhibits endothelial and tumor cell invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res 2000;60:5410-3.
    • (2000) Cancer Res , vol.60 , pp. 5410-5413
    • Kim, Y.M.1    Jang, J.W.2    Lee, O.H.3    Yeon, J.4    Choi, E.Y.5    Kim, K.W.6
  • 127
    • 0037052336 scopus 로고    scopus 로고
    • Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin DI
    • Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, et al. Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin DI. J Biol Chem 2002;277: 16464-9.
    • (2002) J Biol Chem , vol.277 , pp. 16464-16469
    • Hanai, J.1    Dhanabal, M.2    Karumanchi, S.A.3    Albanese, C.4    Waterman, M.5    Chan, B.6
  • 128
    • 0036790094 scopus 로고    scopus 로고
    • Endostatin associates with integrin alpha 5 beta 1 and caveolin-1 and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells
    • Wickstrom SA, Alitalo K, Keski-Oja J. Endostatin associates with integrin alpha 5 beta 1 and caveolin-1 and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells. Cancer Res 2002;62:5580-9.
    • (2002) Cancer Res , vol.62 , pp. 5580-5589
    • Wickstrom, S.A.1    Alitalo, K.2    Keski-Oja, J.3
  • 131
    • 0033957239 scopus 로고    scopus 로고
    • Results of a randomized study of IM862 nasal solution in the treatment of AIDS-related Kaposi's sarcoma
    • Tulpule A, Scadden DT, Espina BM, Cabriales S, Howard W, Shea K, et al. Results of a randomized study of IM862 nasal solution in the treatment of AIDS-related Kaposi's sarcoma. J Clin Oncol 2000;18:716-23.
    • (2000) J Clin Oncol , vol.18 , pp. 716-723
    • Tulpule, A.1    Scadden, D.T.2    Espina, B.M.3    Cabriales, S.4    Howard, W.5    Shea, K.6
  • 133
    • 0001015122 scopus 로고    scopus 로고
    • The effects of preparations of human chorionic gonadotropin on AIDS-related Kaposi's sarcoma
    • published errata appears in N Engl J Med 1997;336:60 and 1997;336:1115
    • Gill PS, Lunardi-Iskandar Y, Louie S, Tulpule A, Zheng T, Espina BM, et al. The effects of preparations of human chorionic gonadotropin on AIDS-related Kaposi's sarcoma. N Engl J Med 1996;335:1261-9 [published errata appears in N Engl J Med 1997;336:60 and 1997;336:1115].
    • (1996) N Engl J Med , vol.335 , pp. 1261-1269
    • Gill, P.S.1    Lunardi-Iskandar, Y.2    Louie, S.3    Tulpule, A.4    Zheng, T.5    Espina, B.M.6
  • 134
    • 0030656284 scopus 로고    scopus 로고
    • Phase I study of human chorionic gonadotropin given subcutaneously to patients with acquired immunodeficiency-related mucocutaneous Kaposi's sarcoma
    • Gill PS, McLaughlin T, Espina BM, Tulpule A, Louie S, Lunardi-Iskander Y, et al. Phase I study of human chorionic gonadotropin given subcutaneously to patients with acquired immunodeficiency-related mucocutaneous Kaposi's sarcoma. J Natl Cancer Inst 1997;89:1797-802.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1797-1802
    • Gill, P.S.1    McLaughlin, T.2    Espina, B.M.3    Tulpule, A.4    Louie, S.5    Lunardi-Iskander, Y.6
  • 135
    • 0033585450 scopus 로고    scopus 로고
    • The butler did it: Search for killer(s) of Kaposi's sarcoma cells in preparations of human chorionic gonadotropin
    • Darzynkiewicz Z. The butler did it: search for killer(s) of Kaposi's sarcoma cells in preparations of human chorionic gonadotropin. J Natl Cancer Inst 1999;91:104-6.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 104-106
    • Darzynkiewicz, Z.1
  • 136
    • 0034076201 scopus 로고    scopus 로고
    • Thalidomide-induced antigen-specific immune stimulation in patients with human immunodeficiency virus type 1 and tuberculosis
    • Bekker L-G, Haslett P, Maartens G, et al. Thalidomide-induced antigen-specific immune stimulation in patients with human immunodeficiency virus type 1 and tuberculosis. J Inf Dis 2000;181:954-65.
    • (2000) J Inf Dis , vol.181 , pp. 954-965
    • Bekker, L.-G.1    Haslett, P.2    Maartens, G.3
  • 137
    • 0000387375 scopus 로고    scopus 로고
    • The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M tuberculosis infection
    • Klausner JD, Makonkawkeyoon S, Akarasewi P, et al. The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M tuberculosis infection. J Acquir Immune Defic Syndr Hum Retrovirol 1996;11:247-57.
    • (1996) J Acquir Immune Defic Syndr Hum Retrovirol , vol.11 , pp. 247-257
    • Klausner, J.D.1    Makonkawkeyoon, S.2    Akarasewi, P.3
  • 138
    • 0034692466 scopus 로고    scopus 로고
    • Thalidomide for the treatment of AIDS-associated wasting
    • Kaplan G, Thomas S, Fierer DS, et al. Thalidomide for the treatment of AIDS-associated wasting. AIDS Res Hum Retroviruses 2000;16:1345-55.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 1345-1355
    • Kaplan, G.1    Thomas, S.2    Fierer, D.S.3
  • 139
    • 8244247121 scopus 로고    scopus 로고
    • Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection
    • National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group
    • Jacobson JM, Greenspan JS, Spritzler J, et al. Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med 1997;336:1487-93.
    • (1997) N Engl J Med , vol.336 , pp. 1487-1493
    • Jacobson, J.M.1    Greenspan, J.S.2    Spritzler, J.3
  • 140
    • 0029800251 scopus 로고    scopus 로고
    • Effects of thalidomide on HIV-associated wasting syndrome: A randomized, double-blind, placebo-controlled clinical trial
    • Reyes-Teran G, Sierra-Madero JG, Martinez del Cerro V, et al. Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double-blind, placebo-controlled clinical trial. AIDS 1996;10:1501-7.
    • (1996) AIDS , vol.10 , pp. 1501-1507
    • Reyes-Teran, G.1    Sierra-Madero, J.G.2    Martinez del Cerro, V.3
  • 141
    • 0036013757 scopus 로고    scopus 로고
    • Randomized, open-label, phase II AIDS Clinical Trials Group study of two doses of interferon alfa-2b combined with didanosine in patients with AIDS-associated Kaposi's sarcoma: Efficacy of daily low-dose interferon
    • Krown SE, Li P, Von Roenn JH, Paredes J, Huang J, Testa MA. Randomized, open-label, phase II AIDS Clinical Trials Group study of two doses of interferon alfa-2b combined with didanosine in patients with AIDS-associated Kaposi's sarcoma: Efficacy of daily low-dose interferon. J Interferon Cytokine Res 2002;22:295-303.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 295-303
    • Krown, S.E.1    Li, P.2    Von Roenn, J.H.3    Paredes, J.4    Huang, J.5    Testa, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.