Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

Journal of Immunology

Volumn 181, Issue 4, 2008, Pages 2277-2284

  Xiao, Sheng ^a   Jin, Hulin ^a   Korn, Thomas ^a,b   Liu, Sue M ^a   Oukka, Mohamed ^a   Lim, Bing ^a   Kuchroo, Vijay K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 21; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ALPHA; RETINOIC ACID; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; INTERLEUKIN 17; INTERLEUKIN 23 RECEPTOR, MOUSE; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; INTERLEUKIN-23 RECEPTOR, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; SMAD3 PROTEIN, MOUSE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ARTICLE; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL LINE; CELL MATURATION; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG EFFECT; EFFECTOR CELL; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH17 CELL; ANIMAL; AUTOIMMUNE DISEASE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; GENETICS; HELPER CELL; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-17; INTERLEUKIN-6; INTERLEUKINS; LYMPHOCYTE COUNT; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; T-LYMPHOCYTES, HELPER-INDUCER; TRANSFORMING GROWTH FACTOR BETA; TRETINOIN;

EID: 53149137849     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.4.2277     Document Type: Article

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