The role of glutathione S-transferase- and cytochrome P450-dependent metabolism in the olfactory toxicity of methyl iodide in the rat

Archives of Toxicology

Volumn 72, Issue 7, 1998, Pages 420-428

  Chamberlain, M P ^a   Lock, E A ^b   Gaskell, B A ^b   Reed, C J ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Cytochromes P450; Glutathione S transferases; Methyl iodide; Olfactory toxicity Glutathione

Indexed keywords

CYTOCHROME P450; GLUTATHIONE TRANSFERASE; METHYL IODIDE; PHORONE;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; LIVER NECROSIS; NONHUMAN; OLFACTORY EPITHELIUM; OLFACTORY SYSTEM; PATHOGENESIS; PRIORITY JOURNAL; RAT; TOXICITY;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG SYNERGISM; EPITHELIUM; GLUTATHIONE TRANSFERASE; HYDROCARBONS, IODINATED; KETONES; MALE; NASAL CAVITY; RATS; RATS, WISTAR; RESPIRATORY SYSTEM; SMELL;

ANIMALIA;

EID: 0031864744     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050522     Document Type: Article

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