Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration

Regulatory Toxicology and Pharmacology

Volumn 36, Issue 1, 2002, Pages 51-68

  Gentry, P Robinan ^a,c   Covington, Tammie R ^a,c   Andersen, Melvin E ^b   Clewell III, Harvey J ^a,c  

^a KS Crump Division   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c ENVIRON INTERNATIONAL CORPORATION   (United States)

Author keywords

2 propanol; Acetone; Isopropanol; Physiologically based pharmacokinetic model; Reference concentration (RfC); Reference dose (RfD); Risk assessment

Indexed keywords

2 PROPANOL; ACETONE;

ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MODEL; BLOOD LEVEL; CHRONIC TOXICITY; COGNITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEVELOPMENT; DOSE CALCULATION; DOSIMETRY; EXPOSURE; FEMALE; FETUS WEIGHT; HUMAN; HUMAN EXPERIMENT; METABOLITE; NONHUMAN; PHYSIOLOGY; PREGNANCY; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SIMULATION;

ANIMALIA;

EID: 0036978894     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1006/rtph.2002.1540     Document Type: Article

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