The use of physiologically based models to integrate diverse data sets and reduce uncertainty in the prediction of perchlorate and iodide kinetics across life stages and species

Toxicology and Industrial Health

Volumn 17, Issue 10, 2001, Pages 210-222

  Clewell, Rebecca A ^a   Merrill, Elaine A ^a   Robinson, Peter J ^b  

^a WRIGHT PATTERSON AIR FORCE BASE   (United States)

^b ALION SCIENCE AND TECHNOLOGY   (United States)

Author keywords

extrapolation; human; iodide inhibition; PBPK model; perchlorate; rat; rick assessment

Indexed keywords

DRINKING WATER; IODIDE; PERCHLORATE; THYROID HORMONE;

BIOACCUMULATION; CONFERENCE PAPER; DISEASE ASSOCIATION; DOSE RESPONSE; DOSIMETRY; ENVIRONMENTAL EXPOSURE; HEALTH STATUS; HOMEOSTASIS; KINETICS; RISK ASSESSMENT; SPECIES DIFFERENCE; VALIDATION PROCESS; WATER CONTAMINATION;

AGE FACTORS; ANIMALS; FEMALE; FORECASTING; HUMANS; IODIDES; KINETICS; LACTATION; MALE; MODELS, BIOLOGICAL; PERCHLORIC ACID; RATS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SODIUM COMPOUNDS; WATER SUPPLY;

EID: 0035384499     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1191/0748233701th108oa     Document Type: Article

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