The toxicity of styrene to the nasal epithelium of mice and rats: Studies on the mode of action and relevance to humans

Chemico-Biological Interactions

Volumn 137, Issue 2, 2001, Pages 185-202

  Green, Trevor ^a   Lee, Robert ^a   Toghill, Alison ^a   Meadowcroft, Susan ^a   Lund, Valerie ^b   Foster, John ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Human; Nasal toxicity; Rodent; Styrene

Indexed keywords

5 PHENYL 1 PENTYNE; BENZENE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 2E1; CYTOCHROME P450 2F2; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; STYRENE OXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DETOXIFICATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; MALE; METABOLITE; NONHUMAN; OLFACTORY EPITHELIUM; RAT;

ALKYNES; ANIMALS; BENZENE DERIVATIVES; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MICE; MICROSOMES; MUTAGENS; NASAL MUCOSA; RATS; RATS, SPRAGUE-DAWLEY; STYRENE;

RODENTIA;

EID: 0035979676     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(01)00236-8     Document Type: Article

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