-
1
-
-
0035424759
-
An ancient cluster of Wnt paralogues
-
Nusse R (2001) An ancient cluster of Wnt paralogues. Trends Genet 17:443
-
(2001)
Trends Genet
, vol.17
, pp. 443
-
-
Nusse, R.1
-
2
-
-
51149118892
-
Deciphering the function of canonical Wnt signals in development and disease: Conditional loss-and gain-of-function mutations of beta-catenin in mice
-
Grigoryan T, Wend P, Klaus A, Birchmeier W (2008) Deciphering the function of canonical Wnt signals in development and disease: Conditional loss-and gain-of-function mutations of beta-catenin in mice. Genes Dev 22:2308-2341
-
(2008)
Genes Dev
, vol.22
, pp. 2308-2341
-
-
Grigoryan, T.1
Wend, P.2
Klaus, A.3
Birchmeier, W.4
-
3
-
-
41549115361
-
Wnt/beta-catenin signaling: New (and old) players and new insights
-
Huang H, He X (2008) Wnt/beta-catenin signaling: New (and old) players and new insights. Curr Opin Cell Biol 20:119-125
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 119-125
-
-
Huang, H.1
He, X.2
-
4
-
-
59649100796
-
Wnt signaling controls the fate of mesenchymal stem cells
-
Ling L, Nurcombe V, Cool SM (2008) Wnt signaling controls the fate of mesenchymal stem cells. Gene 433:1-7
-
(2008)
Gene
, vol.433
, pp. 1-7
-
-
Ling, L.1
Nurcombe, V.2
Cool, S.M.3
-
5
-
-
43049144313
-
Wnt signaling and stem cell control
-
Nusse R (2008) Wnt signaling and stem cell control. Cell Res 18:523-527
-
(2008)
Cell Res
, vol.18
, pp. 523-527
-
-
Nusse, R.1
-
6
-
-
62849106337
-
Beta-catenin hits chromatin: Regulation of Wnt target gene activation
-
Mosimann C, Hausmann G, Basler K (2009) Beta-catenin hits chromatin: Regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 10:276-286
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 276-286
-
-
Mosimann, C.1
Hausmann, G.2
Basler, K.3
-
7
-
-
24744467833
-
Vital elements of the Wnt-frizzled signalling pathway in the nervous system
-
Li F, Chong ZZ, Maiese K (2005) Vital elements of the Wnt-frizzled signalling pathway in the nervous system. Curr Neurovasc Res 2:331-340
-
(2005)
Curr Neurovasc Res
, vol.2
, pp. 331-340
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
8
-
-
29844447503
-
Winding through the WNT pathway during cellular development and demise
-
Li F, Chong ZZ, Maiese K (2006) Winding through the WNT pathway during cellular development and demise. Histol Histopathol 21:103-124
-
(2006)
Histol Histopathol
, vol.21
, pp. 103-124
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
10
-
-
0029844909
-
Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
-
Reichsman F, Smith L, Cumberledge S (1996) Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction. J Cell Biol 135:819-827
-
(1996)
J Cell Biol
, vol.135
, pp. 819-827
-
-
Reichsman, F.1
Smith, L.2
Cumberledge, S.3
-
11
-
-
0031792355
-
Cytoskeletal reorganization by soluble Wnt-3a protein signalling
-
Shibamoto S, Higano K, Takada R et al (1998) Cytoskeletal reorganization by soluble Wnt-3a protein signalling. Genes Cells 3:659-670
-
(1998)
Genes Cells
, vol.3
, pp. 659-670
-
-
Shibamoto, S.1
Higano, K.2
Takada, R.3
-
12
-
-
0024453493
-
Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication
-
van den Heuvel M, Nusse R, Johnston P, Lawrence PA (1989) Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication. Cell 59:739-749
-
(1989)
Cell
, vol.59
, pp. 739-749
-
-
Van Den Heuvel, M.1
Nusse, R.2
Johnston, P.3
Lawrence, P.A.4
-
13
-
-
0028842141
-
Signalling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface
-
Bejsovec A, Wieschaus E (1995) Signalling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. Genetics 139:309-320
-
(1995)
Genetics
, vol.139
, pp. 309-320
-
-
Bejsovec, A.1
Wieschaus, E.2
-
14
-
-
0032759039
-
Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo
-
Moline MM, Southern C, Bejsovec A (1999) Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 126:4375-4384
-
(1999)
Development
, vol.126
, pp. 4375-4384
-
-
Moline, M.M.1
Southern, C.2
Bejsovec, A.3
-
15
-
-
0035368514
-
Regulated endocytic routing modulates wingless signalling in drosophila embryos
-
Dubois L, Lecourtois M, Alexandre C et al (2001) Regulated endocytic routing modulates wingless signalling in Drosophila embryos. Cell 105:613-624
-
(2001)
Cell
, vol.105
, pp. 613-624
-
-
Dubois, L.1
Lecourtois, M.2
Alexandre, C.3
-
16
-
-
0035823004
-
Argosomes: A potential vehicle for the spread of morphogens through epithelia
-
Greco V, Hannus M, Eaton S (2001) Argosomes: A potential vehicle for the spread of morphogens through epithelia. Cell 106:633-645
-
(2001)
Cell
, vol.106
, pp. 633-645
-
-
Greco, V.1
Hannus, M.2
Eaton, S.3
-
17
-
-
0035917498
-
Apical localization of wingless transcripts is required for wingless signalling
-
Simmonds AJ, dosSantos G, Livne-Bar I, Krause HM (2001) Apical localization of wingless transcripts is required for wingless signalling. Cell 105:197-207
-
(2001)
Cell
, vol.105
, pp. 197-207
-
-
Simmonds, A.J.1
DosSantos, G.2
Livne-Bar, I.3
Krause, H.M.4
-
18
-
-
0035917422
-
Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles
-
Wilkie GS, Davis I (2001) Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. Cell 105:209-219
-
(2001)
Cell
, vol.105
, pp. 209-219
-
-
Wilkie, G.S.1
Davis, I.2
-
19
-
-
0032529161
-
Differential recruitment of dishevelled provides signalling specificity in the planar cell polarity and Wingless signalling pathways
-
Axelrod JD, Miller JR, Shulman JM et al (1998) Differential recruitment of Dishevelled provides signalling specificity in the planar cell polarity and Wingless signalling pathways. Genes Dev 12:2610-2622
-
(1998)
Genes Dev
, vol.12
, pp. 2610-2622
-
-
Axelrod, J.D.1
Miller, J.R.2
Shulman, J.M.3
-
20
-
-
0032504052
-
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signalling
-
Boutros M, Paricio N, Strutt DI, Mlodzik M (1998) Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signalling. Cell 94:109-118
-
(1998)
Cell
, vol.94
, pp. 109-118
-
-
Boutros, M.1
Paricio, N.2
Strutt, D.I.3
Mlodzik, M.4
-
21
-
-
33846990139
-
Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signalling
-
Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY (2005) Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signalling. J Biol 4:3
-
(2005)
J Biol
, vol.4
, pp. 3
-
-
Itoh, K.1
Brott, B.K.2
Bae, G.U.3
Ratcliffe, M.J.4
Sokol, S.Y.5
-
22
-
-
0034084768
-
Roles of Wnt proteins in neural development and maintenance
-
Patapoutian A, Reichardt LF (2000) Roles of Wnt proteins in neural development and maintenance. Curr Opin Neurobiol 10:392-399
-
(2000)
Curr Opin Neurobiol
, vol.10
, pp. 392-399
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
23
-
-
33846396811
-
Frizzled/PCP signalling: A conserved mechanism regulating cell polarity and directed motility
-
Seifert JR, Mlodzik M (2006) Frizzled/PCP signalling: A conserved mechanism regulating cell polarity and directed motility. Nat Rev Genet 8:126-138
-
(2006)
Nat Rev Genet
, vol.8
, pp. 126-138
-
-
Seifert, J.R.1
Mlodzik, M.2
-
24
-
-
33750047472
-
Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/GMP/Ca2+ pathway
-
Ma L, Wang HY (2006) Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/GMP/Ca2+ pathway. J Biol Chem 281:30990-31001
-
(2006)
J Biol Chem
, vol.281
, pp. 30990-31001
-
-
Ma, L.1
Wang, H.Y.2
-
25
-
-
34748812548
-
The frizzled family of unconventional G-protein-coupled receptors
-
Schulte G, Bryja V (2007) The frizzled family of unconventional G-protein-coupled receptors. Trends Pharmacol Sci 28:518-525
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 518-525
-
-
Schulte, G.1
Bryja, V.2
-
26
-
-
22944457221
-
International union of pharmacology. XLVI. G protein-coupled receptor list
-
Foord SM, Bonner TI, Neubig RR et al (2005) International union of pharmacology. XLVI. G protein-coupled receptor list. Pharmacol Rev 57:279-288
-
(2005)
Pharmacol Rev
, vol.57
, pp. 279-288
-
-
Foord, S.M.1
Bonner, T.I.2
Neubig, R.R.3
-
28
-
-
0027205387
-
Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases
-
Wilson C, Goberdhan DC, Steller H (1993) Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases. Proc Natl Acad Sci USA 90:7109-7113
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7109-7113
-
-
Wilson, C.1
Goberdhan, D.C.2
Steller, H.3
-
29
-
-
0030888061
-
Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase
-
Song L, Fricker LD (1997) Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase. J Biol Chem 272:10543-10550
-
(1997)
J Biol Chem
, vol.272
, pp. 10543-10550
-
-
Song, L.1
Fricker, L.D.2
-
30
-
-
0033591253
-
Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart
-
Yan W, Sheng N, Seto M, Morser J, Wu Q (1999) Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart. J Biol Chem 274:14926-14935
-
(1999)
J Biol Chem
, vol.274
, pp. 14926-14935
-
-
Yan, W.1
Sheng, N.2
Seto, M.3
Morser, J.4
Wu, Q.5
-
31
-
-
0034727099
-
Arrow encodes an LDL-receptor-related protein essential for Wingless signalling
-
Wehrli M, Dougan ST, Caldwell K et al (2000) Arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 407:527-530
-
(2000)
Nature
, vol.407
, pp. 527-530
-
-
Wehrli, M.1
Dougan, S.T.2
Caldwell, K.3
-
32
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signalling pathway
-
Mao J, Wang J, Liu B et al (2001) Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signalling pathway. Mol Cell 7:801-809
-
(2001)
Mol Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
-
33
-
-
0037343952
-
Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3-beta activity
-
Tolwinski NS, Wehrli M, Rives A et al (2003) Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3-beta activity. Dev Cell 4:407-418
-
(2003)
Dev Cell
, vol.4
, pp. 407-418
-
-
Tolwinski, N.S.1
Wehrli, M.2
Rives, A.3
-
34
-
-
11844286903
-
Wnt pathway activation: New relations and locations
-
Bejsovec A (2005) Wnt pathway activation: New relations and locations. Cell 120:11-14
-
(2005)
Cell
, vol.120
, pp. 11-14
-
-
Bejsovec, A.1
-
35
-
-
5344273899
-
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
-
Lu W, Yamamoto V, Ortega B, Baltimore D (2004) Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell 119:97-108
-
(2004)
Cell
, vol.119
, pp. 97-108
-
-
Lu, W.1
Yamamoto, V.2
Ortega, B.3
Baltimore, D.4
-
36
-
-
33646124944
-
A dedicated wnt secretion factor
-
Ching W, Nusse R (2006) A dedicated Wnt secretion factor. Cell 125:432-433
-
(2006)
Cell
, vol.125
, pp. 432-433
-
-
Ching, W.1
Nusse, R.2
-
37
-
-
33646134826
-
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signalling cells
-
Bänziger C, Soldini D, Schütt C et al (2006) Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signalling cells. Cell 125:509-522
-
(2006)
Cell
, vol.125
, pp. 509-522
-
-
Bänziger, C.1
Soldini, D.2
Schütt, C.3
-
38
-
-
33646123992
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
-
Bartscherer K, Pelte N, Ingelfinger D, Boutros M (2006) Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125:523-533
-
(2006)
Cell
, vol.125
, pp. 523-533
-
-
Bartscherer, K.1
Pelte, N.2
Ingelfinger, D.3
Boutros, M.4
-
39
-
-
4143090605
-
The mammalian retromer regulates transcytosis of the polymeric immunoglobin receptor
-
Vergés M, Luton F, Gruber C et al (2004) The mammalian retromer regulates transcytosis of the polymeric immunoglobin receptor. Nat Cell Biol 6:763-769
-
(2004)
Nat Cell Biol
, vol.6
, pp. 763-769
-
-
Vergés, M.1
Luton, F.2
Gruber, C.3
-
40
-
-
33646592268
-
Wnt gradient formation requires retromer function in Wnt-producing cells
-
Coudreuse DY, Roel G, Betist MC et al (2006) Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312:921-924
-
(2006)
Science
, vol.312
, pp. 921-924
-
-
Coudreuse, D.Y.1
Roel, G.2
Betist, M.C.3
-
41
-
-
84875174587
-
Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
-
Hsieh JC, Rattner A, Smallwood PM, Nathans J (1999) Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc Natl Acad Sci USA 382:225-230
-
(1999)
Proc Natl Acad Sci USA
, vol.382
, pp. 225-230
-
-
Hsieh, J.C.1
Rattner, A.2
Smallwood, P.M.3
Nathans, J.4
-
42
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/betacatenin signalling: Arrows point the way
-
He X, Semenov M, Tamai K, Zeng X (2004) LDL receptor-related proteins 5 and 6 in Wnt/betacatenin signalling: Arrows point the way. Development 131:1663-1677
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
43
-
-
28644439005
-
A dualkinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng X, Tamai K, Doble B et al (2005) A dualkinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438: 873-877
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
-
44
-
-
0036159121
-
The Ror receptor tyrosine kinase family
-
Forrester WC (2002) The Ror receptor tyrosine kinase family. Cell Mol Life Sci 59:83-96
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 83-96
-
-
Forrester, W.C.1
-
45
-
-
10744219743
-
The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway
-
Oishi I, Suzuki H, Onishi N et al (2003) The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway. Genes Cells 8:645-654
-
(2003)
Genes Cells
, vol.8
, pp. 645-654
-
-
Oishi, I.1
Suzuki, H.2
Onishi, N.3
-
46
-
-
33646241997
-
Purifi ed Wnt5a protein activates or inhibits beta-catenin-TCF signalling depending on receptor context
-
Mikels AJ, Nusse R (2006) Purifi ed Wnt5a protein activates or inhibits beta-catenin-TCF signalling depending on receptor context. PLoS Biol 4:e115
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
47
-
-
0032128173
-
From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
-
Moon RT, Kimelman D (1998) From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus. BioEssays 20:536-545
-
(1998)
BioEssays
, vol.20
, pp. 536-545
-
-
Moon, R.T.1
Kimelman, D.2
-
48
-
-
0034026842
-
The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning
-
Sumanas S, Strege P, Heasman J, Ekker SC (2000) The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development 127:1981-1990
-
(2000)
Development
, vol.127
, pp. 1981-1990
-
-
Sumanas, S.1
Strege, P.2
Heasman, J.3
Ekker, S.C.4
-
49
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434:843-850
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
50
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek V, Barker N, Moerer P et al (1998) Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 19:379-383
-
(1998)
Nat Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
-
51
-
-
23844455584
-
Mitogenic influence of human R-spondin1 on the intestinal epithelium
-
Kim KA, Kakitani M, Zhao J et al (2005) Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science 309:1256-1259
-
(2005)
Science
, vol.309
, pp. 1256-1259
-
-
Kim, K.A.1
Kakitani, M.2
Zhao, J.3
-
52
-
-
0027945654
-
Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
-
van Genderen C, Okamura RM, Farinas I et al (1994) Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8:2691-2703
-
(1994)
Genes Dev
, vol.8
, pp. 2691-2703
-
-
Van Genderen, C.1
Okamura, R.M.2
Farinas, I.3
-
53
-
-
0038274074
-
Stem cells in the skin: Waste not, Wnt not
-
Alonso L, Fuchs E (2003) Stem cells in the skin: Waste not, Wnt not. Genes Dev 17:1189-1200
-
(2003)
Genes Dev
, vol.17
, pp. 1189-1200
-
-
Alonso, L.1
Fuchs, E.2
-
54
-
-
0035907041
-
Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B et al (2001) beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105:533-545
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
-
55
-
-
22344441322
-
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells
-
Lowry WE, Blanpain C, Nowak JA et al (2005) Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev 19:1596-1611
-
(2005)
Genes Dev
, vol.19
, pp. 1596-1611
-
-
Lowry, W.E.1
Blanpain, C.2
Nowak, J.A.3
-
56
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya T, Duncan AW, Ailles L et al (2003) A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423:409-414
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
-
57
-
-
0035980128
-
Synergistic activation of the Wnt signalling pathway by Dvl and casein kinase Iepsilon
-
Kishida M, Hino SI, Michiue T et al (2001) Synergistic activation of the Wnt signalling pathway by Dvl and casein kinase Iepsilon. J Biol Chem 276:33147-33155
-
(2001)
J Biol Chem
, vol.276
, pp. 33147-33155
-
-
Kishida, M.1
Hino, S.I.2
Michiue, T.3
-
58
-
-
0037313260
-
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signalling
-
Ishitani T, Ninomiya-Tsuji J, Matsumoto K (2003) Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signalling. Mol Cell Biol 23:1379-1389
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1379-1389
-
-
Ishitani, T.1
Ninomiya-Tsuji, J.2
Matsumoto, K.3
-
59
-
-
2542452082
-
Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed mammary epithelial cells
-
Graham NA, Asthagiri AR (2004) Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed mammary epithelial cells. J Biol Chem 279:23517-23524
-
(2004)
J Biol Chem
, vol.279
, pp. 23517-23524
-
-
Graham, N.A.1
Asthagiri, A.R.2
-
60
-
-
33746910279
-
Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB
-
Li F, Chong ZZ, Maiese K (2006) Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB. Curr Neurovasc Res 3:187-201
-
(2006)
Curr Neurovasc Res
, vol.3
, pp. 187-201
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
61
-
-
12744262866
-
Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins
-
Chen AE, Ginty DD, Fan CM (2005) Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins. Nature 433:317-322
-
(2005)
Nature
, vol.433
, pp. 317-322
-
-
Chen, A.E.1
Ginty, D.D.2
Fan, C.M.3
-
62
-
-
0034692686
-
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways
-
D'Amico M, Hulit J, Amanatullah DF et al (2000) The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J Biol Chem 275:32649-32657
-
(2000)
J Biol Chem
, vol.275
, pp. 32649-32657
-
-
D'Amico, M.1
Hulit, J.2
Amanatullah, D.F.3
-
63
-
-
0038001141
-
PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements
-
Kinoshita N, Iioka H, Miyakoshi A, Ueno N (2003) PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes Dev 17:1663-1676
-
(2003)
Genes Dev
, vol.17
, pp. 1663-1676
-
-
Kinoshita, N.1
Iioka, H.2
Miyakoshi, A.3
Ueno, N.4
-
64
-
-
33845802651
-
Noncanonical Wnt signalling through G protein-linked PKC delta activation promotes bone formation
-
Tu X, Joeng KS, Nakayama KI et al (2007) Noncanonical Wnt signalling through G protein-linked PKC delta activation promotes bone formation. Dev Cell 12:113-127
-
(2007)
Dev Cell
, vol.12
, pp. 113-127
-
-
Tu, X.1
Joeng, K.S.2
Nakayama, K.I.3
-
65
-
-
2942726272
-
Wnt11 signalling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells
-
Ouko L, Ziegler TR, Gu LH et al (2004) Wnt11 signalling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells. J Biol Chem 279:26707-26715
-
(2004)
J Biol Chem
, vol.279
, pp. 26707-26715
-
-
Ouko, L.1
Ziegler, T.R.2
Gu, L.H.3
-
66
-
-
16444372007
-
Wnt-5a has tumour suppressor activity in thyroid carcinoma
-
Kremenevskaja N, von Wasielewski R, Rao AS et al (2005) Wnt-5a has tumour suppressor activity in thyroid carcinoma. Oncogene 24: 2144-2154
-
(2005)
Oncogene
, vol.24
, pp. 2144-2154
-
-
Kremenevskaja, N.1
Von Wasielewski, R.2
Rao, A.S.3
-
67
-
-
33746990262
-
Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42- casein kinase 1 signalling in human mammary epithelial cells
-
Dejmek J, Safholm A, Kamp Nielsen C et al (2006) Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1 signalling in human mammary epithelial cells. Mol Cell Biol 26:6024-6036
-
(2006)
Mol Cell Biol
, vol.26
, pp. 6024-6036
-
-
Dejmek, J.1
Safholm, A.2
Kamp Nielsen, C.3
-
68
-
-
33645789040
-
A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells
-
Safholm A, Leandersson K, Dejmek J et al (2006) A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J Biol Chem 281:2740-2749
-
(2006)
J Biol Chem
, vol.281
, pp. 2740-2749
-
-
Safholm, A.1
Leandersson, K.2
Dejmek, J.3
-
69
-
-
0043234810
-
Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity
-
Westfall TA, Brimeyer R, Twedt J et al (2003) Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity. J Cell Biol 162:889-898
-
(2003)
J Cell Biol
, vol.162
, pp. 889-898
-
-
Westfall, T.A.1
Brimeyer, R.2
Twedt, J.3
-
70
-
-
0033600239
-
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF
-
Ishitani T, Ninomiya-Tsuji J, Nagai S et al (1999) The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature 399:798-802
-
(1999)
Nature
, vol.399
, pp. 798-802
-
-
Ishitani, T.1
Ninomiya-Tsuji, J.2
Nagai, S.3
-
71
-
-
33947169909
-
Wnt11-R signalling regulates a calcium sensitive EMT event essential for dorsal fi n development of Xenopus
-
Garriock RJ, Krieg PA (2007) Wnt11-R signalling regulates a calcium sensitive EMT event essential for dorsal fi n development of Xenopus. Dev Biol 304:127-140
-
(2007)
Dev Biol
, vol.304
, pp. 127-140
-
-
Garriock, R.J.1
Krieg, P.A.2
-
72
-
-
21244479003
-
Essential role of non-canonical Wnt signalling in neural crest migration
-
De Calisto J, Araya C, Marchant L et al (2005) Essential role of non-canonical Wnt signalling in neural crest migration. Development 132:2587-2597
-
(2005)
Development
, vol.132
, pp. 2587-2597
-
-
De Calisto, J.1
Araya, C.2
Marchant, L.3
-
73
-
-
11844291274
-
Noncanonical Wnt signalling regulates midline convergence of organ primordial during zebrafi sh development
-
Matsui T, Raya A, Kawakami Y et al (2005) Noncanonical Wnt signalling regulates midline convergence of organ primordial during zebrafi sh development. Genes Dev 19:164-175
-
(2005)
Genes Dev
, vol.19
, pp. 164-175
-
-
Matsui, T.1
Raya, A.2
Kawakami, Y.3
-
74
-
-
22144446755
-
Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding
-
Jenny A, Reynolds-Kenneally J, Das G et al (2005) Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nat Cell Biol 7:691-697
-
(2005)
Nat Cell Biol
, vol.7
, pp. 691-697
-
-
Jenny, A.1
Reynolds-Kenneally, J.2
Das, G.3
-
75
-
-
0142042539
-
Frizzled signalling and cell polarisation in Drosophila and vertebrates
-
Strutt D (2003) Frizzled signalling and cell polarisation in Drosophila and vertebrates. Development 130:4501-4513
-
(2003)
Development
, vol.130
, pp. 4501-4513
-
-
Strutt, D.1
-
76
-
-
18744382449
-
The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signalling
-
Hikasa H, Shibata M, Hiratami I, Taira M (2002) The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signalling. Development 129: 5227-5239
-
(2002)
Development
, vol.129
, pp. 5227-5239
-
-
Hikasa, H.1
Shibata, M.2
Hiratami, I.3
Taira, M.4
-
77
-
-
0033930669
-
RGS proteins inhibit Xwnt-8 signalling in Xenopus embryonic development
-
Wu C, Zeng Q, Blumer KJ, Muslin AJ (2000) RGS proteins inhibit Xwnt-8 signalling in Xenopus embryonic development. Development 127:2773-2784
-
(2000)
Development
, vol.127
, pp. 2773-2784
-
-
Wu, C.1
Zeng, Q.2
Blumer, K.J.3
Muslin, A.J.4
-
78
-
-
0035368394
-
G protein signalling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway
-
Liu T, DeCostanzo AJ, Liu X et al (2001) G protein signalling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway. Science 292:1718-1722
-
(2001)
Science
, vol.292
, pp. 1718-1722
-
-
Liu, T.1
DeCostanzo, A.J.2
Liu, X.3
-
79
-
-
11844299003
-
Trimeric G protein-dependent frizzled signalling in Drosophila
-
Katanaev VL, Ponzielli R, Semeriva M, Tomlinson A (2005) Trimeric G protein-dependent frizzled signalling in Drosophila. Cell 120:111-122
-
(2005)
Cell
, vol.120
, pp. 111-122
-
-
Katanaev, V.L.1
Ponzielli, R.2
Semeriva, M.3
Tomlinson, A.4
-
80
-
-
33645919975
-
Role of PKA as a negative regulator of PCP signalling pathway during Xenopus gastrulation movements
-
Park E, Kim GH, Choi SC, Han JK (2006) Role of PKA as a negative regulator of PCP signalling pathway during Xenopus gastrulation movements. Dev Biol 292:344-357
-
(2006)
Dev Biol
, vol.292
, pp. 344-357
-
-
Park, E.1
Kim, G.H.2
Choi, S.C.3
Han, J.K.4
-
81
-
-
0029959105
-
Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis
-
Hoang B, Moos M Jr, Vukicevic S, Luyten FP (1996) Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis. J Biol Chem 271:26131-26137
-
(1996)
J Biol Chem
, vol.271
, pp. 26131-26137
-
-
Hoang, B.1
Moos Jr., M.2
Vukicevic, S.3
Luyten, F.P.4
-
82
-
-
0030905162
-
A family of secreted proteins contains homology to the cysteinerich ligand-binding domain of frizzled receptors
-
Rattner A, Hsieh JC, Smallwood PM et al (1997) A family of secreted proteins contains homology to the cysteinerich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA 94:2859-2863
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2859-2863
-
-
Rattner, A.1
Hsieh, J.C.2
Smallwood, P.M.3
-
83
-
-
0033523005
-
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signalling
-
Bafico A, Gazit A, Pramila T et al (1999) Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signalling. J Biol Chem 274:16180-16187
-
(1999)
J Biol Chem
, vol.274
, pp. 16180-16187
-
-
Bafico, A.1
Gazit, A.2
Pramila, T.3
-
84
-
-
0030799081
-
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signalling
-
Lin K, Wang S, Julius MA et al (1997) The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signalling. Proc Natl Acad Sci USA 94:11196-11200
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11196-11200
-
-
Lin, K.1
Wang, S.2
Julius, M.A.3
-
86
-
-
0034649592
-
Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling
-
Wu W, Glinka A, Delius H, Niehrs C (2000) Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling. Curr Biol 10:1611-1614
-
(2000)
Curr Biol
, vol.10
, pp. 1611-1614
-
-
Wu, W.1
Glinka, A.2
Delius, H.3
Niehrs, C.4
-
87
-
-
12344310615
-
Functions of heparan sulfate proteoglycans in cell signalling during development
-
Lin X (2004) Functions of heparan sulfate proteoglycans in cell signalling during development. Development 131:6009-6021
-
(2004)
Development
, vol.131
, pp. 6009-6021
-
-
Lin, X.1
-
88
-
-
46449101840
-
Epithelial morphogenesis and intestinal cancer: New insights in signalling mechanisms
-
Fre S, Vignjevic D, Schoumacher M et al (2008) Epithelial morphogenesis and intestinal cancer: New insights in signalling mechanisms. Cancer Res 100:85-111
-
(2008)
Cancer Res
, vol.100
, pp. 85-111
-
-
Fre, S.1
Vignjevic, D.2
Schoumacher, M.3
-
90
-
-
24044493254
-
Wnt-3a regulates chondrocyte differentiation via c-Jun/AP-1 pathway
-
Hwang SG, Yu SS, Lee SW, Chun JS (2005) Wnt-3a regulates chondrocyte differentiation via c-Jun/AP-1 pathway. FEBS Lett 579:4837-4842
-
(2005)
FEBS Lett
, vol.579
, pp. 4837-4842
-
-
Hwang, S.G.1
Yu, S.S.2
Lee, S.W.3
Chun, J.S.4
-
91
-
-
4644276225
-
Wnt/betacatenin signalling is sufficient and necessary for synovial joint formation
-
Guo X, Day TF, Jiang X et al (2004) Wnt/betacatenin signalling is sufficient and necessary for synovial joint formation. Genes Dev 18:2404-2417
-
(2004)
Genes Dev
, vol.18
, pp. 2404-2417
-
-
Guo, X.1
Day, T.F.2
Jiang, X.3
-
92
-
-
13444302715
-
Sequential roles of Hedgehog and Wnt signalling in osteoblast development
-
Hu H, Hilton MJ, Tu X et al (2005) Sequential roles of Hedgehog and Wnt signalling in osteoblast development. Development 132:49-60
-
(2005)
Development
, vol.132
, pp. 49-60
-
-
Hu, H.1
Hilton, M.J.2
Tu, X.3
-
93
-
-
0035479835
-
New aspects of Wnt signalling pathways in higher vertebrates
-
Huelsken J, Birchmeier W (2001) New aspects of Wnt signalling pathways in higher vertebrates. Curr Opin Genet Dev 11:547-553
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 547-553
-
-
Huelsken, J.1
Birchmeier, W.2
-
94
-
-
0032916351
-
Wnt targets. Repression and activation
-
Nusse R (1999) Wnt targets. Repression and activation. Trends Genet 15:1-3
-
(1999)
Trends Genet
, vol.15
, pp. 1-3
-
-
Nusse, R.1
-
96
-
-
0035827698
-
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2
-
Howe LR, Crawford HC, Subbaramaiah K et al (2001) PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. J Biol Chem 276:20108-20115
-
(2001)
J Biol Chem
, vol.276
, pp. 20108-20115
-
-
Howe, L.R.1
Crawford, H.C.2
Subbaramaiah, K.3
-
97
-
-
18644373146
-
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, Sancho E, Verweij C et al (2002) The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111:241-250
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van De Wetering, M.1
Sancho, E.2
Verweij, C.3
-
98
-
-
0037461931
-
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter
-
Wu S, Cetinkaya C, Munoz-Alonso MJLN et al (2003) Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene 22:351-360
-
(2003)
Oncogene
, vol.22
, pp. 351-360
-
-
Wu, S.1
Cetinkaya, C.2
Munoz-Alonso, M.J.L.N.3
-
99
-
-
0037155243
-
Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
-
Tice DA, Soloviev I, Polakis P (2002) Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes. J Biol Chem 277:6118-6123
-
(2002)
J Biol Chem
, vol.277
, pp. 6118-6123
-
-
Tice, D.A.1
Soloviev, I.2
Polakis, P.3
-
100
-
-
1642536445
-
Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion
-
Staal FJ, Weerkamp F, Baert MR et al (2004) Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J Immunol 172:1099-1108
-
(2004)
J Immunol
, vol.172
, pp. 1099-1108
-
-
Staal, F.J.1
Weerkamp, F.2
Baert, M.R.3
-
101
-
-
34247863937
-
Long-term effect of diabetes and its treatment on cognitive function
-
Jacobson AM, Musen G, Ryan CM et al (2007) Long-term effect of diabetes and its treatment on cognitive function. N Engl J Med 356:1842-1852
-
(2007)
N Engl J Med
, vol.356
, pp. 1842-1852
-
-
Jacobson, A.M.1
Musen, G.2
Ryan, C.M.3
-
102
-
-
34547444891
-
Mechanistic insights into diabetes mellitus and oxidative stress
-
Maiese K, Chong ZZ, Shang YC (2007) Mechanistic insights into diabetes mellitus and oxidative stress. Curr Med Chem 14:1689-1699
-
(2007)
Curr Med Chem
, vol.14
, pp. 1689-1699
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
103
-
-
33645745733
-
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
-
Monnier L, Mas E, Ginet C et al (2006) Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 295:1681-1687
-
(2006)
JAMA
, vol.295
, pp. 1681-1687
-
-
Monnier, L.1
Mas, E.2
Ginet, C.3
-
104
-
-
33745314333
-
Protection of INS-1 cells from free fatty acidinduced apoptosis by targeting hOGG1 to mitochondria
-
Rachek LI, Thornley NP, Grishko VI et al (2006) Protection of INS-1 cells from free fatty acidinduced apoptosis by targeting hOGG1 to mitochondria. Diabetes 55:1022-1028
-
(2006)
Diabetes
, vol.55
, pp. 1022-1028
-
-
Rachek, L.I.1
Thornley, N.P.2
Grishko, V.I.3
-
105
-
-
35548999739
-
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes
-
Pospisilik JA, Knauf C, Joza N et al (2007) Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell 131:476-491
-
(2007)
Cell
, vol.131
, pp. 476-491
-
-
Pospisilik, J.A.1
Knauf, C.2
Joza, N.3
-
106
-
-
33847014094
-
Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans
-
Lehman DM, Hunt KJ, Leach RJ et al (2007) Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes 56:389-393
-
(2007)
Diabetes
, vol.56
, pp. 389-393
-
-
Lehman, D.M.1
Hunt, K.J.2
Leach, R.J.3
-
107
-
-
33750458964
-
Polymorphisms of the low-density lipoprotein receptorrelated protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study
-
Guo YF, Xiong DH, Shen H et al (2006) Polymorphisms of the low-density lipoprotein receptorrelated protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study. J Med Genet 43:798-803
-
(2006)
J Med Genet
, vol.43
, pp. 798-803
-
-
Guo, Y.F.1
Xiong, D.H.2
Shen, H.3
-
108
-
-
33847656105
-
LRP6 mutation in a family with early coronary disease and metabolic risk factors
-
Mani A, Radhakrishnan J, Wang H et al (2007) LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science 315:1278-1282
-
(2007)
Science
, vol.315
, pp. 1278-1282
-
-
Mani, A.1
Radhakrishnan, J.2
Wang, H.3
-
109
-
-
34548406873
-
Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats
-
Aslanidi G, Kroutov V, Philipsberg G et al (2007) Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats. Am J Physiol Endocrinol Metab 293: E726-E736
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Aslanidi, G.1
Kroutov, V.2
Philipsberg, G.3
-
110
-
-
5644245234
-
Erythropoietin in the brain: Can the promise to protect be fulfilled?
-
Maiese K, Li F, Chong ZZ (2004) Erythropoietin in the brain: Can the promise to protect be fulfilled? Trends Pharmacol Sci 25:577-583
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 577-583
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
111
-
-
11244333356
-
New avenues of exploration for erythropoietin
-
Maiese K, Li F, Chong ZZ (2005) New avenues of exploration for erythropoietin. JAMA 293:90-95
-
(2005)
JAMA
, vol.293
, pp. 90-95
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
112
-
-
34547797469
-
Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signalling
-
Chong ZZ, Shang YC, Maiese K (2007) Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signalling. Curr Neurovasc Res 4:194-204
-
(2007)
Curr Neurovasc Res
, vol.4
, pp. 194-204
-
-
Chong, Z.Z.1
Shang, Y.C.2
Maiese, K.3
-
113
-
-
24744467833
-
Vital elements of the Wnt-frizzled signalling pathway in the nervous system
-
Li F, Chong ZZ, Maiese K (2005) Vital elements of the Wnt-frizzled signalling pathway in the nervous system. Curr Neurovasc Res 2:331-340
-
(2005)
Curr Neurovasc Res
, vol.2
, pp. 331-340
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
114
-
-
29844447503
-
Winding through the WNT pathway during cellular development and demise
-
Li F, Chong ZZ, Maiese K (2006) Winding through the WNT pathway during cellular development and demise. Histol Histopathol 21:103-124
-
(2006)
Histol Histopathol
, vol.21
, pp. 103-124
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
115
-
-
2342597875
-
Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP
-
Morin PJ, Medina M, Semenov M et al (2004) Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP. Neurobiol Dis 16:59-67
-
(2004)
Neurobiol Dis
, vol.16
, pp. 59-67
-
-
Morin, P.J.1
Medina, M.2
Semenov, M.3
-
116
-
-
0035879075
-
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase
-
Mudher A, Chapman S, Richardson J et al (2001) Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase. J Neurosci 21:4987-4995
-
(2001)
J Neurosci
, vol.21
, pp. 4987-4995
-
-
Mudher, A.1
Chapman, S.2
Richardson, J.3
-
117
-
-
33846195085
-
Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signalling
-
Salins P, Shawesh S, He Y et al (2007) Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signalling. Neurosci Lett 412:211-216
-
(2007)
Neurosci Lett
, vol.412
, pp. 211-216
-
-
Salins, P.1
Shawesh, S.2
He, Y.3
-
118
-
-
0242330191
-
Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA
-
Barandon L, Couffinhal T, Ezan J et al (2003) Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA. Circulation 108:2282-2289
-
(2003)
Circulation
, vol.108
, pp. 2282-2289
-
-
Barandon, L.1
Couffinhal, T.2
Ezan, J.3
-
119
-
-
33847023085
-
Interruption of Wnt signalling attenuates the onset of pressure overload-induced cardiac hypertrophy
-
van de Schans VA, van den Borne SW, Strzelecka AE et al (2007) Interruption of Wnt signalling attenuates the onset of pressure overload-induced cardiac hypertrophy. Hypertension 49:473-480
-
(2007)
Hypertension
, vol.49
, pp. 473-480
-
-
Van De Schans, V.A.1
Van Den Borne, S.W.2
Strzelecka, A.E.3
-
120
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK et al (1991) Identification of FAP locus genes from chromosome 5q21. Science 253:661-665
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
-
121
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Y et al (1991) Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253:665-669
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
-
122
-
-
0030975671
-
Constitutive transcriptional activation by a betacatenin-Tcf complex in APC-/-colon carcinoma
-
Korinek V, Barker N, Morin PJ et al (1997) Constitutive transcriptional activation by a betacatenin-Tcf complex in APC-/-colon carcinoma. Science 275:1784-1787
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
-
123
-
-
0030949463
-
Activation of beta-catenin-Tcf signalling in colon cancer by mutations in beta-catenin or APC
-
Morin PJ, Sparks AB, Korinek V et al (1997) Activation of beta-catenin-Tcf signalling in colon cancer by mutations in beta-catenin or APC. Science 275:1787-1790
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
124
-
-
0345356929
-
Wnt5a inhibits B cell proliferation and functions as a tumour suppressor in hematopoietic tissue
-
Liang H, Chen Q, Coles AH et al (2003) Wnt5a inhibits B cell proliferation and functions as a tumour suppressor in hematopoietic tissue. Cancer Cell 4:349-360
-
(2003)
Cancer Cell
, vol.4
, pp. 349-360
-
-
Liang, H.1
Chen, Q.2
Coles, A.H.3
-
125
-
-
0033895709
-
Wnt signalling and cancer
-
Polakis P (2000) Wnt signalling and cancer. Genes Dev 14:1837-1851
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
127
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker N, Clevers H (2006) Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov 5:997-1014
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
128
-
-
0037138743
-
Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
-
Thun MJ, Henley SJ, Patrono C (2002) Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst 94:252-266
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 252-266
-
-
Thun, M.J.1
Henley, S.J.2
Patrono, C.3
-
129
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signalling axis
-
Castellone MD, Teramoto H, Williams BO et al (2005) Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signalling axis. Science 310:1504-1510
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
-
130
-
-
22544475938
-
Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer
-
Shao J, Jung C, Liu C, Sheng H (2005) Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer. J Biol Chem 280:26565-26572
-
(2005)
J Biol Chem
, vol.280
, pp. 26565-26572
-
-
Shao, J.1
Jung, C.2
Liu, C.3
Sheng, H.4
-
132
-
-
0347481364
-
Trans-repression of beta-catenin activity by nuclear receptors
-
Shah S, Hecht A, Pestell R, Byers SW (2003) Trans-repression of beta-catenin activity by nuclear receptors. J Biol Chem 278:48137-48145
-
(2003)
J Biol Chem
, vol.278
, pp. 48137-48145
-
-
Shah, S.1
Hecht, A.2
Pestell, R.3
Byers, S.W.4
-
133
-
-
0043032524
-
Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway
-
Xiao JH, Ghosn C, Hinchman C et al (2003) Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway. J Biol Chem 278:29954-29962
-
(2003)
J Biol Chem
, vol.278
, pp. 29954-29962
-
-
Xiao, J.H.1
Ghosn, C.2
Hinchman, C.3
-
134
-
-
4644229397
-
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
-
Palmer HG, Larriba MJ, Garcia JM et al (2004) The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat Med 10:917-919
-
(2004)
Nat Med
, vol.10
, pp. 917-919
-
-
Palmer, H.G.1
Larriba, M.J.2
Garcia, J.M.3
-
135
-
-
33644850904
-
The molecular basis of vitamin D receptor and beta-catenin crossregulation
-
Shah S, Islam MN, Dakshanamurthy S et al (2006) The molecular basis of vitamin D receptor and beta-catenin crossregulation. Mol Cell 21:799-809
-
(2006)
Mol Cell
, vol.21
, pp. 799-809
-
-
Shah, S.1
Islam, M.N.2
Dakshanamurthy, S.3
-
136
-
-
60849097553
-
Cancer stem cells: Controversial or just misunderstood?
-
Jordan CT (2009) Cancer stem cells: Controversial or just misunderstood? Cell Stem Cell 4:203-205
-
(2009)
Cell Stem Cell
, vol.4
, pp. 203-205
-
-
Jordan, C.T.1
|