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Volumn 8, Issue 2, 2007, Pages 126-138

Frizzled/PCP signalling: A conserved mechanism regulating cell polarity and directed motility

Author keywords

[No Author keywords available]

Indexed keywords

FRIZZLED PROTEIN;

EID: 33846396811     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg2042     Document Type: Review
Times cited : (408)

References (137)
  • 1
    • 0016723010 scopus 로고
    • The determination of polarity in the developing insect retina
    • Lawrence, P. A. & Shelton, P. M. J. The determination of polarity in the developing insect retina. J. Embryol. Exp. Morph. 33, 471-486 (1975).
    • (1975) J. Embryol. Exp. Morph , vol.33 , pp. 471-486
    • Lawrence, P.A.1    Shelton, P.M.J.2
  • 2
    • 0026955974 scopus 로고
    • The genetic control of tissue polarity in Drosophila
    • Adler, P. N. The genetic control of tissue polarity in Drosophila. BioEssays 14, 735-741 (1992).
    • (1992) BioEssays , vol.14 , pp. 735-741
    • Adler, P.N.1
  • 3
    • 0020004250 scopus 로고
    • A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster
    • Gubb, D. & Garcia-Bellido, A. A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. J. Embryol. Exp. Morphol. 68, 37-57 (1982).
    • (1982) J. Embryol. Exp. Morphol , vol.68 , pp. 37-57
    • Gubb, D.1    Garcia-Bellido, A.2
  • 5
    • 0036111153 scopus 로고    scopus 로고
    • Planar signaling and morphogenesis in Drosophila
    • Adler, P. N. Planar signaling and morphogenesis in Drosophila. Dev. Cell 2, 525-535 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 525-535
    • Adler, P.N.1
  • 6
    • 27744538492 scopus 로고    scopus 로고
    • Planar cell polarization: An emerging model points in the right direction
    • Klein, T. J. & Mlodzik, M. Planar cell polarization: an emerging model points in the right direction. Annu. Rev. Cell Dev. Biol. 21, 155-176 (2005).
    • (2005) Annu. Rev. Cell Dev. Biol , vol.21 , pp. 155-176
    • Klein, T.J.1    Mlodzik, M.2
  • 7
    • 0036843202 scopus 로고    scopus 로고
    • Planar cell polarization: Do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?
    • Mlodzik, M. Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet. 18, 564-571 (2002).
    • (2002) Trends Genet , vol.18 , pp. 564-571
    • Mlodzik, M.1
  • 8
    • 0142042539 scopus 로고    scopus 로고
    • Frizzled signalling and cell polarisation in Drosophila and vertebrates
    • Strutt, D. Frizzled signalling and cell polarisation in Drosophila and vertebrates. Development 130, 4501-4513 (2003).
    • (2003) Development , vol.130 , pp. 4501-4513
    • Strutt, D.1
  • 9
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of β-cateninin-dependent Wnt signaling
    • Veeman, M. T., Axelrod, J. D. & Moon, R. T. A second canon. Functions and mechanisms of β-cateninin-dependent Wnt signaling. Dev. Cell 5, 367-377 (2003).
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 10
    • 0036087024 scopus 로고    scopus 로고
    • Convergent extension: The molecular control of polarized cell movement during embryonic development
    • Wallingford, J. B., Fraser, S. E. & Harland, R. M. Convergent extension: the molecular control of polarized cell movement during embryonic development. Dev. Cell 2, 695-706 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 695-706
    • Wallingford, J.B.1    Fraser, S.E.2    Harland, R.M.3
  • 11
    • 0037032828 scopus 로고    scopus 로고
    • Shaping the vertebrate body plan by polarized embryonic cell movements
    • Keller, R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science 298, 1950-1954 (2002).
    • (2002) Science , vol.298 , pp. 1950-1954
    • Keller, R.1
  • 12
    • 0036716748 scopus 로고    scopus 로고
    • Convergence and extension in vertebrate gastrulae: Cell movements according to or in search of identity?
    • Myers, D. C., Sepich, D. S. & Solnica-Krezel, L. Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity? Trends Genet. 18, 447-455 (2002).
    • (2002) Trends Genet , vol.18 , pp. 447-455
    • Myers, D.C.1    Sepich, D.S.2    Solnica-Krezel, L.3
  • 13
    • 0842301559 scopus 로고    scopus 로고
    • The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila
    • Bellaiche, Y., Beaudoin-Massiani, O., Stuttem, I. & Schweisguth, F. The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila. Development 131, 469-478 (2004).
    • (2004) Development , vol.131 , pp. 469-478
    • Bellaiche, Y.1    Beaudoin-Massiani, O.2    Stuttem, I.3    Schweisguth, F.4
  • 14
    • 0035144288 scopus 로고    scopus 로고
    • Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division
    • Bellaiche, Y., Gho, M., Kaltschmidt, J. A., Brand, A. H. & Schweisguth, F. Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division. Nature Cell Biol. 3, 50-57 (2001).
    • (2001) Nature Cell Biol , vol.3 , pp. 50-57
    • Bellaiche, Y.1    Gho, M.2    Kaltschmidt, J.A.3    Brand, A.H.4    Schweisguth, F.5
  • 15
    • 33644523762 scopus 로고    scopus 로고
    • Wnt signals can function as positional cues in establishing cell polarity
    • Goldstein, B., Takeshita, H., Mizumoto, K. & Sawa, H. Wnt signals can function as positional cues in establishing cell polarity. Dev. Cell 10, 391-396 (2006).
    • (2006) Dev. Cell , vol.10 , pp. 391-396
    • Goldstein, B.1    Takeshita, H.2    Mizumoto, K.3    Sawa, H.4
  • 16
    • 0037991533 scopus 로고    scopus 로고
    • Montcouquiol, M. et al.Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423, 173-177 (2003). This paper puts on the PCP map the polarization of the sensory cells in the mouse cochlea. A nice genetic study of the role of Vangl2/Stbm in the mouse.
    • Montcouquiol, M. et al.Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423, 173-177 (2003). This paper puts on the PCP map the polarization of the sensory cells in the mouse cochlea. A nice genetic study of the role of Vangl2/Stbm in the mouse.
  • 17
    • 10744227509 scopus 로고    scopus 로고
    • Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse
    • Curtin, J. A. et al.Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr. Biol. 13, 1129-1133 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 1129-1133
    • Curtin, J.A.1
  • 19
    • 3042694211 scopus 로고    scopus 로고
    • Guo, N., Hawkins, C. & Nathans, J. Frizzled6 controls hair patterning in mice. Proc. Natl Acad. Sci. USA 101, 9277-9281 (2004). A knockout of the Fz6 gene showed 'eclassical' PCP defects in mouse fur, analogous to the defects in D. melanogaster wing or abdomen cuticle, showing the conserved PCP features in the epidermis of insects and mammals.
    • Guo, N., Hawkins, C. & Nathans, J. Frizzled6 controls hair patterning in mice. Proc. Natl Acad. Sci. USA 101, 9277-9281 (2004). A knockout of the Fz6 gene showed 'eclassical' PCP defects in mouse fur, analogous to the defects in D. melanogaster wing or abdomen cuticle, showing the conserved PCP features in the epidermis of insects and mammals.
  • 20
    • 33644624937 scopus 로고    scopus 로고
    • Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
    • Park, T. J., Haigo, S. L. & Wallingford, J. B. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nature Genet. 38, 303-311 (2006).
    • (2006) Nature Genet , vol.38 , pp. 303-311
    • Park, T.J.1    Haigo, S.L.2    Wallingford, J.B.3
  • 21
    • 33747838464 scopus 로고    scopus 로고
    • Polycystic kidney disease: Cell division without a c(l)ue?
    • Simons, M. & Walz, G. Polycystic kidney disease: cell division without a c(l)ue? Kidney Int. 70, 854-864 (2006).
    • (2006) Kidney Int , vol.70 , pp. 854-864
    • Simons, M.1    Walz, G.2
  • 22
    • 33746891890 scopus 로고    scopus 로고
    • The primary cilium as the cell's antenna: Signaling at a sensory organelle
    • Singla, V. & Reiter, J. F. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 313, 629-633 (2006).
    • (2006) Science , vol.313 , pp. 629-633
    • Singla, V.1    Reiter, J.F.2
  • 23
    • 0034729910 scopus 로고    scopus 로고
    • Mechanisms of convergence and extension by cell intercalation
    • Keller, R. et al.Mechanisms of convergence and extension by cell intercalation. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355, 897-922 (2000).
    • (2000) Philos. Trans. R. Soc. Lond., B, Biol. Sci , vol.355 , pp. 897-922
    • Keller, R.1
  • 24
    • 0031457327 scopus 로고    scopus 로고
    • Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels
    • Adler, P. N., Krasnow, R. E. & Liu, J. Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels. Curr. Biol. 7, 940-949 (1997).
    • (1997) Curr. Biol , vol.7 , pp. 940-949
    • Adler, P.N.1    Krasnow, R.E.2    Liu, J.3
  • 25
    • 0037767761 scopus 로고    scopus 로고
    • Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning
    • Bastock, R., Strutt, H. & Strutt, D. Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning. Development 130, 3007-3014 (2003).
    • (2003) Development , vol.130 , pp. 3007-3014
    • Bastock, R.1    Strutt, H.2    Strutt, D.3
  • 26
    • 22144446755 scopus 로고    scopus 로고
    • Jenny, A., Reynolds-Kenneally, J., Das, G., Burnett, M. & Mlodzik, M. Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nature Cell Biol. 7, 691-697 (2005). Genetic and physical interactions between DGO, PK and DSH define that DGO and PK compete for DSH binding and that, in contrast to PK, DGO promotes DSH mediated Fz/PCP signalling.
    • Jenny, A., Reynolds-Kenneally, J., Das, G., Burnett, M. & Mlodzik, M. Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nature Cell Biol. 7, 691-697 (2005). Genetic and physical interactions between DGO, PK and DSH define that DGO and PK compete for DSH binding and that, in contrast to PK, DGO promotes DSH mediated Fz/PCP signalling.
  • 27
    • 0037013168 scopus 로고    scopus 로고
    • Tree, D. R. et al.Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 109, 371-381 (2002). This paper analyses the role of PK and shows that it antagonizes DSH membrane localization. The potential feedback loops among the core PCP genes are proposed.
    • Tree, D. R. et al.Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 109, 371-381 (2002). This paper analyses the role of PK and shows that it antagonizes DSH membrane localization. The potential feedback loops among the core PCP genes are proposed.
  • 28
  • 29
    • 4444240972 scopus 로고    scopus 로고
    • Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing
    • Matakatsu, H. & Blair, S. S. Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131, 3785-3794 (2004).
    • (2004) Development , vol.131 , pp. 3785-3794
    • Matakatsu, H.1    Blair, S.S.2
  • 30
    • 33745899356 scopus 로고    scopus 로고
    • Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins
    • Matakatsu, H. & Blair, S. S. Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. Development 133, 2315-2324 (2006).
    • (2006) Development , vol.133 , pp. 2315-2324
    • Matakatsu, H.1    Blair, S.S.2
  • 31
    • 0037172663 scopus 로고    scopus 로고
    • The cadherins Fat and Dachsous regulate dorsal/ventral signaling in the Drosophila eye
    • Rawls, A. S., Guinto, J. B. & Wolff, T. The cadherins Fat and Dachsous regulate dorsal/ventral signaling in the Drosophila eye. Curr. Biol 12, 1021-1026 (2002).
    • (2002) Curr. Biol , vol.12 , pp. 1021-1026
    • Rawls, A.S.1    Guinto, J.B.2    Wolff, T.3
  • 32
    • 12344251185 scopus 로고    scopus 로고
    • Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression
    • Simon, M. A. Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression. Development 131, 6175-6184 (2004).
    • (2004) Development , vol.131 , pp. 6175-6184
    • Simon, M.A.1
  • 33
    • 0037040407 scopus 로고    scopus 로고
    • Yang, C., Axelrod, J. D. & Simon, M. A. Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108, 675-688 (2002). This is the first paper to put the Fat-Dachsous (FT-DS) cadherins on the map in the context of PCP establishment. It indicates that the FT-DS interaction might influence FZ activity.
    • Yang, C., Axelrod, J. D. & Simon, M. A. Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108, 675-688 (2002). This is the first paper to put the Fat-Dachsous (FT-DS) cadherins on the map in the context of PCP establishment. It indicates that the FT-DS interaction might influence FZ activity.
  • 34
    • 0033518294 scopus 로고    scopus 로고
    • The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification
    • Zeidler, M. P., Perrimon, N. & Strutt, D. I. The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Curr. Biol. 9, 1363-1372 (1999).
    • (1999) Curr. Biol , vol.9 , pp. 1363-1372
    • Zeidler, M.P.1    Perrimon, N.2    Strutt, D.I.3
  • 35
    • 0034672019 scopus 로고    scopus 로고
    • Multiple roles for four-jointed in planar polarity and limb patterning
    • Zeidler, M. P., Perrimon, N. & Strutt, D. I. Multiple roles for four-jointed in planar polarity and limb patterning. Dev. Biol. 228, 181-196 (2000).
    • (2000) Dev. Biol , vol.228 , pp. 181-196
    • Zeidler, M.P.1    Perrimon, N.2    Strutt, D.I.3
  • 36
    • 1342284810 scopus 로고    scopus 로고
    • Cleavage and secretion is not required for Four-jointed function in Drosophila patterning
    • Strutt, H., Mundy, J., Hofstra, K. & Strutt, D. Cleavage and secretion is not required for Four-jointed function in Drosophila patterning. Development 131, 881-890 (2004).
    • (2004) Development , vol.131 , pp. 881-890
    • Strutt, H.1    Mundy, J.2    Hofstra, K.3    Strutt, D.4
  • 37
    • 0037324628 scopus 로고    scopus 로고
    • The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor
    • Fanto, M. et al.The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor. Development 130, 763-774 (2003).
    • (2003) Development , vol.130 , pp. 763-774
    • Fanto, M.1
  • 38
    • 0035873390 scopus 로고    scopus 로고
    • Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
    • Axelrod, J. D. Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling. Genes Dev. 15, 1182-1187 (2001).
    • (2001) Genes Dev , vol.15 , pp. 1182-1187
    • Axelrod, J.D.1
  • 39
    • 6944227630 scopus 로고    scopus 로고
    • Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes
    • Das, G., Jenny, A., Klein, T. J., Eaton, S. & Mlodzik, M. Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development 131, 4467-4476 (2004).
    • (2004) Development , vol.131 , pp. 4467-4476
    • Das, G.1    Jenny, A.2    Klein, T.J.3    Eaton, S.4    Mlodzik, M.5
  • 40
    • 0036111640 scopus 로고    scopus 로고
    • The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye
    • Das, G., Reynolds-Kenneally, J. & Mlodzik, M. The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye. Dev. Cell 2, 655-666 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 655-666
    • Das, G.1    Reynolds-Kenneally, J.2    Mlodzik, M.3
  • 41
    • 0037076213 scopus 로고    scopus 로고
    • Asymmetric localization of frizzled and the determination of Notch-dependent cell fate in the Drosophila eye
    • Strutt, D., Johnson, R., Cooper, K. & Bray, S. Asymmetric localization of frizzled and the determination of Notch-dependent cell fate in the Drosophila eye. Curr. Biol. 12, 813-824 (2002).
    • (2002) Curr. Biol , vol.12 , pp. 813-824
    • Strutt, D.1    Johnson, R.2    Cooper, K.3    Bray, S.4
  • 42
    • 0035108427 scopus 로고    scopus 로고
    • Strutt, D. I. Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing. Mol. Cell 7, 367-375 (2001). This work shows the asymmetric localization of FZ (as a FZ-GFP transgene) to one side of a wing cell undergoing Fz/PCP signalling. Further works followed this example for the other core PCP factors.
    • Strutt, D. I. Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing. Mol. Cell 7, 367-375 (2001). This work shows the asymmetric localization of FZ (as a FZ-GFP transgene) to one side of a wing cell undergoing Fz/PCP signalling. Further works followed this example for the other core PCP factors.
  • 43
    • 19344364294 scopus 로고    scopus 로고
    • Wu, J., Klein, T. J. & Mlodzik, M. Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. PLoS Biol. 2, 1004-1014 (2004). This paper shows that FZ has to be localized apically as a prerequisite for its function in PCP signalling. It maps the sequences associated/required for the apical localization of FZ.
    • Wu, J., Klein, T. J. & Mlodzik, M. Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. PLoS Biol. 2, 1004-1014 (2004). This paper shows that FZ has to be localized apically as a prerequisite for its function in PCP signalling. It maps the sequences associated/required for the apical localization of FZ.
  • 44
    • 0041736696 scopus 로고    scopus 로고
    • Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling
    • Jenny, A., Darken, R. S., Wilson, P. A. & Mlodzik, M. Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling. EMBO J. 22, 4409-4420 (2003).
    • (2003) EMBO J , vol.22 , pp. 4409-4420
    • Jenny, A.1    Darken, R.S.2    Wilson, P.A.3    Mlodzik, M.4
  • 45
    • 19344363080 scopus 로고    scopus 로고
    • The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye
    • Djiane, A., Yogev, S. & Mlodzik, M. The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell 121, 621-631 (2005).
    • (2005) Cell , vol.121 , pp. 621-631
    • Djiane, A.1    Yogev, S.2    Mlodzik, M.3
  • 46
    • 33646941288 scopus 로고    scopus 로고
    • Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals
    • Montcouquiol, M. et al.Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J. Neurosci. 26, 5265-5275 (2006).
    • (2006) J. Neurosci , vol.26 , pp. 5265-5275
    • Montcouquiol, M.1
  • 47
    • 0033520466 scopus 로고    scopus 로고
    • Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled
    • Usui, T. et al.Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98, 585-595 (1999).
    • (1999) Cell , vol.98 , pp. 585-595
    • Usui, T.1
  • 48
    • 0031918915 scopus 로고    scopus 로고
    • Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila
    • Wolff, T. & Rubin, G. M. Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development 125, 1149-1159 (1998).
    • (1998) Development , vol.125 , pp. 1149-1159
    • Wolff, T.1    Rubin, G.M.2
  • 49
    • 0033523927 scopus 로고    scopus 로고
    • Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila
    • Lu, B., Usui, T., Uemura, T., Jan, L. & Jan, Y. N. Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila. Curr. Biol. 9, 1247-1250 (1999).
    • (1999) Curr. Biol , vol.9 , pp. 1247-1250
    • Lu, B.1    Usui, T.2    Uemura, T.3    Jan, L.4    Jan, Y.N.5
  • 50
    • 25144504913 scopus 로고    scopus 로고
    • Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway
    • Wang, J. et al.Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nature Genet. 37, 980-985 (2005).
    • (2005) Nature Genet , vol.37 , pp. 980-985
    • Wang, J.1
  • 51
    • 33645637038 scopus 로고    scopus 로고
    • The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells
    • Wang, Y., Guo, N. & Nathans, J. The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J. Neurosci. 26, 2147-2156 (2006).
    • (2006) J. Neurosci , vol.26 , pp. 2147-2156
    • Wang, Y.1    Guo, N.2    Nathans, J.3
  • 52
    • 0034604076 scopus 로고    scopus 로고
    • Dishevelled controls cell polarity during Xenopus gastrulation
    • Wallingford, J. B. et al.Dishevelled controls cell polarity during Xenopus gastrulation. Nature 405, 81-85 (2000).
    • (2000) Nature , vol.405 , pp. 81-85
    • Wallingford, J.B.1
  • 53
    • 0038001141 scopus 로고    scopus 로고
    • PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements
    • Kinoshita, N., Iioka, H., Miyakoshi, A. & Ueno, N. PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes Dev. 17, 1663-1676 (2003).
    • (2003) Genes Dev , vol.17 , pp. 1663-1676
    • Kinoshita, N.1    Iioka, H.2    Miyakoshi, A.3    Ueno, N.4
  • 54
    • 30544439006 scopus 로고    scopus 로고
    • Ciruna, B., Jenny, A., Lee, D., Mlodzik, M. & Schier, A. F. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 439, 220-224 (2006). The first data set to analyse PCP protein distribution in in vivo time-lapse movies in vertebrates. In combination with the genetic power of zebrafish this is the best reference for PCP factor localization during CE.
    • Ciruna, B., Jenny, A., Lee, D., Mlodzik, M. & Schier, A. F. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 439, 220-224 (2006). The first data set to analyse PCP protein distribution in in vivo time-lapse movies in vertebrates. In combination with the genetic power of zebrafish this is the best reference for PCP factor localization during CE.
  • 55
    • 11844299000 scopus 로고    scopus 로고
    • Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells
    • Jiang, D., Munro, E. M. & Smith, W. C. Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells. Curr. Biol. 15, 79-85 (2005).
    • (2005) Curr. Biol , vol.15 , pp. 79-85
    • Jiang, D.1    Munro, E.M.2    Smith, W.C.3
  • 56
    • 12344296412 scopus 로고    scopus 로고
    • Amonlirdviman, K. et al.Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science 307, 423-426 (2005). This work provides the first mathematical modelling of PCP establishment in the D. melanogaster wing. It serves a starting point for future models.
    • Amonlirdviman, K. et al.Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science 307, 423-426 (2005). This work provides the first mathematical modelling of PCP establishment in the D. melanogaster wing. It serves a starting point for future models.
  • 57
    • 7244239298 scopus 로고    scopus 로고
    • Lawrence, P. A., Casal, J. & Struhl, G. Cell interactions and planar polarity in the abdominal epidermis of Drosophila. Development 131, 4651-4664 (2004). This work defines the PCP features of the abdominal cuticle of D. melanogaster in a detailed manner.
    • Lawrence, P. A., Casal, J. & Struhl, G. Cell interactions and planar polarity in the abdominal epidermis of Drosophila. Development 131, 4651-4664 (2004). This work defines the PCP features of the abdominal cuticle of D. melanogaster in a detailed manner.
  • 58
    • 33644979436 scopus 로고    scopus 로고
    • Establishment and maintenance of planar epithelial cell polarity by asymmetric cadherin bridges: A computer model
    • Le Garrec, J. F., Lopez, P. & Kerszberg, M. Establishment and maintenance of planar epithelial cell polarity by asymmetric cadherin bridges: a computer model. Dev. Dyn. 235, 235-246 (2006).
    • (2006) Dev. Dyn , vol.235 , pp. 235-246
    • Le Garrec, J.F.1    Lopez, P.2    Kerszberg, M.3
  • 59
    • 33745653586 scopus 로고    scopus 로고
    • Klein, T. J., Jenny, A., Djiane, A. & Mlodzik, M. CKIε/discs overgrown promotes both Wnt-Fz/β-catenin and Fz/PCP signaling in Drosophila. Curr. Biol. 16, 1337-1343 (2006).
    • Klein, T. J., Jenny, A., Djiane, A. & Mlodzik, M. CKIε/discs overgrown promotes both Wnt-Fz/β-catenin and Fz/PCP signaling in Drosophila. Curr. Biol. 16, 1337-1343 (2006).
  • 60
    • 33745637502 scopus 로고    scopus 로고
    • Planar polarity is positively regulated by casein kinase Iε in Drosophila
    • Strutt, H., Price, M. A. & Strutt, D. Planar polarity is positively regulated by casein kinase Iε in Drosophila. Curr. Biol. 16, 1329-1336 (2006).
    • (2006) Curr. Biol , vol.16 , pp. 1329-1336
    • Strutt, H.1    Price, M.A.2    Strutt, D.3
  • 61
    • 0035879317 scopus 로고    scopus 로고
    • The casein kinase I family: Roles in morphogenesis
    • McKay, R. M., Peters, J. M. & Graff, J. M. The casein kinase I family: roles in morphogenesis. Dev. Biol. 235, 378-387 (2001).
    • (2001) Dev. Biol , vol.235 , pp. 378-387
    • McKay, R.M.1    Peters, J.M.2    Graff, J.M.3
  • 62
    • 11844299003 scopus 로고    scopus 로고
    • Trimeric G protein-dependent frizzled signaling in Drosophila
    • Katanaev, V. L., Ponzielli, R., Semeriva, M. & Tomlinson, A. Trimeric G protein-dependent frizzled signaling in Drosophila. Cell 120, 111-122 (2005).
    • (2005) Cell , vol.120 , pp. 111-122
    • Katanaev, V.L.1    Ponzielli, R.2    Semeriva, M.3    Tomlinson, A.4
  • 63
    • 0036638049 scopus 로고    scopus 로고
    • Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A
    • Hannus, M., Feiguin, F., Heisenberg, C. P. & Eaton, S. Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A. Development 129, 3493-3503 (2002).
    • (2002) Development , vol.129 , pp. 3493-3503
    • Hannus, M.1    Feiguin, F.2    Heisenberg, C.P.3    Eaton, S.4
  • 64
    • 33745649658 scopus 로고    scopus 로고
    • XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation
    • Hyodo-Miura, J. et al.XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation. Dev. Cell 11, 69-79 (2006).
    • (2006) Dev. Cell , vol.11 , pp. 69-79
    • Hyodo-Miura, J.1
  • 65
    • 19944372081 scopus 로고    scopus 로고
    • Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development
    • Ossipova, O., Dhawan, S., Sokol, S. & Green, J. B. Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Dev. Cell 8, 829-841 (2005).
    • (2005) Dev. Cell , vol.8 , pp. 829-841
    • Ossipova, O.1    Dhawan, S.2    Sokol, S.3    Green, J.B.4
  • 66
    • 0142115409 scopus 로고    scopus 로고
    • EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye
    • Brown, K. E. & Freeman, M. EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130, 5401-5412 (2003).
    • (2003) Development , vol.130 , pp. 5401-5412
    • Brown, K.E.1    Freeman, M.2
  • 67
    • 0142115410 scopus 로고    scopus 로고
    • EGFR signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6
    • Gaengel, K. & Mlodzik, M. EGFR signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6. Development 130, 5413-5423 (2003).
    • (2003) Development , vol.130 , pp. 5413-5423
    • Gaengel, K.1    Mlodzik, M.2
  • 68
    • 0025990093 scopus 로고
    • The beginning of pattern formation in the Drosophila compound eye: The morphogenetic furrow and the second mitotic wave
    • Wolff, T. & Ready, D. F. The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave. Development 113, 841-850 (1991).
    • (1991) Development , vol.113 , pp. 841-850
    • Wolff, T.1    Ready, D.F.2
  • 69
    • 20144367596 scopus 로고    scopus 로고
    • Vertebrate gastrulation: Polarity genes control the matrix
    • Wallingford, J. B. Vertebrate gastrulation: polarity genes control the matrix. Curr. Biol. 15, R414-R416 (2005).
    • (2005) Curr. Biol , vol.15
    • Wallingford, J.B.1
  • 70
    • 0034254659 scopus 로고    scopus 로고
    • Monopolar protrusive activity: A new morphogenic cell behavior in the neural plate dependent on vertical interactions with the mesoderm in Xenopus
    • Elul, T. & Keller, R. Monopolar protrusive activity: a new morphogenic cell behavior in the neural plate dependent on vertical interactions with the mesoderm in Xenopus. Dev. Biol. 224, 3-19 (2000).
    • (2000) Dev. Biol , vol.224 , pp. 3-19
    • Elul, T.1    Keller, R.2
  • 71
    • 0027082578 scopus 로고
    • Cell motility driving mediolateral intercalation in explants of Xenopus laevis
    • Shih, J. & Keller, R. Cell motility driving mediolateral intercalation in explants of Xenopus laevis. Development 116, 901-914 (1992).
    • (1992) Development , vol.116 , pp. 901-914
    • Shih, J.1    Keller, R.2
  • 72
    • 0026461595 scopus 로고
    • On the convergent cell movements of gastrulation in Fundulus
    • Trinkaus, J. P., Trinkaus, M. & Fink, R. D. On the convergent cell movements of gastrulation in Fundulus. J. Exp. Zool. 261, 40-61 (1992).
    • (1992) J. Exp. Zool , vol.261 , pp. 40-61
    • Trinkaus, J.P.1    Trinkaus, M.2    Fink, R.D.3
  • 73
    • 0344896538 scopus 로고    scopus 로고
    • Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation
    • Ulrich, F. et al.Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development 130, 5375-5384 (2003).
    • (2003) Development , vol.130 , pp. 5375-5384
    • Ulrich, F.1
  • 74
    • 0037382333 scopus 로고    scopus 로고
    • The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation
    • Kilian, B. et al.The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mech. Dev. 120, 467-476 (2003).
    • (2003) Mech. Dev , vol.120 , pp. 467-476
    • Kilian, B.1
  • 75
    • 0037018841 scopus 로고    scopus 로고
    • Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements
    • Marlow, F., Topczewski, J., Sepich, D. & Solnica-Krezel, L. Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements. Curr. Biol. 12, 876-884 (2002).
    • (2002) Curr. Biol , vol.12 , pp. 876-884
    • Marlow, F.1    Topczewski, J.2    Sepich, D.3    Solnica-Krezel, L.4
  • 76
    • 0035815280 scopus 로고    scopus 로고
    • Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton
    • Winter, C. G. et al.Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell 105, 81-91 (2001).
    • (2001) Cell , vol.105 , pp. 81-91
    • Winter, C.G.1
  • 78
    • 0033572887 scopus 로고    scopus 로고
    • Planar polarity in the Drosophila eye: A multifaceted view of signaling specificity and crosstalk
    • Mlodzik, M. Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and crosstalk. EMBO J. 18, 6873-6879 (1999).
    • (1999) EMBO J , vol.18 , pp. 6873-6879
    • Mlodzik, M.1
  • 79
    • 0033523280 scopus 로고    scopus 로고
    • Polarity determination in the Drosophila eye
    • Strutt, H. & Strutt, D. Polarity determination in the Drosophila eye. Curr. Opin. Genet. Dev. 9, 442-446 (1999).
    • (1999) Curr. Opin. Genet. Dev , vol.9 , pp. 442-446
    • Strutt, H.1    Strutt, D.2
  • 80
    • 0028364608 scopus 로고
    • Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene
    • Choi, K.-W. & Benzer, S. Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene. Cell 78, 125-136 (1994).
    • (1994) Cell , vol.78 , pp. 125-136
    • Choi, K.-W.1    Benzer, S.2
  • 81
    • 0036898603 scopus 로고    scopus 로고
    • Scabrous controls ommatidial rotation in the Drosophila compound eye
    • Chou, Y. H. & Chien, C. T. Scabrous controls ommatidial rotation in the Drosophila compound eye. Dev. Cell 3, 839-850 (2002).
    • (2002) Dev. Cell , vol.3 , pp. 839-850
    • Chou, Y.H.1    Chien, C.T.2
  • 82
    • 0042926678 scopus 로고    scopus 로고
    • EGF signaling and ommatidial rotation in the Drosophila eye
    • Strutt, H. & Strutt, D. EGF signaling and ommatidial rotation in the Drosophila eye. Curr. Biol. 13, 1451-1457 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 1451-1457
    • Strutt, H.1    Strutt, D.2
  • 83
    • 33749401124 scopus 로고    scopus 로고
    • Cooperative activities of Drosophila DE-Cadherin and DN-Cadherin regulate the cell motility process of ommatidial rotation
    • Mirkovic, I. & Mlodzik, M. Cooperative activities of Drosophila DE-Cadherin and DN-Cadherin regulate the cell motility process of ommatidial rotation. Development 133, 3283-3293 (2006).
    • (2006) Development , vol.133 , pp. 3283-3293
    • Mirkovic, I.1    Mlodzik, M.2
  • 84
    • 28444457747 scopus 로고    scopus 로고
    • Classen, A. K., Anderson, K. I., Marois, E. & Eaton, S. Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev. Cell 9, 805-817 (2005). This paper provides genetic and morphological evidence that one of the functions of Fz/PCP signalling might be the directed recycling of cadherin-containing junctional complexes during cell-shape changes. A similar mechanism might function in the Fz/PCP-regulated cell-motility processes.
    • Classen, A. K., Anderson, K. I., Marois, E. & Eaton, S. Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev. Cell 9, 805-817 (2005). This paper provides genetic and morphological evidence that one of the functions of Fz/PCP signalling might be the directed recycling of cadherin-containing junctional complexes during cell-shape changes. A similar mechanism might function in the Fz/PCP-regulated cell-motility processes.
  • 86
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from Drosophila functions as a Wingless receptor
    • Bhanot, P. et al.A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230 (1996)
    • (1996) Nature , vol.382 , pp. 225-230
    • Bhanot, P.1
  • 87
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan, C. Y. & Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781-810 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 88
    • 0034604096 scopus 로고    scopus 로고
    • Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
    • Heisenberg, C. P. et al.Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405, 76-81 (2000).
    • (2000) Nature , vol.405 , pp. 76-81
    • Heisenberg, C.P.1
  • 89
    • 0034898429 scopus 로고    scopus 로고
    • Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations
    • Lele, Z., Bakkers, J. & Hammerschmidt, M. Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations. Genesis 30, 190-194 (2001).
    • (2001) Genesis , vol.30 , pp. 190-194
    • Lele, Z.1    Bakkers, J.2    Hammerschmidt, M.3
  • 90
    • 0034130385 scopus 로고    scopus 로고
    • Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway
    • Tada, M. & Smith, J. C. Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127, 2227-2238 (2000).
    • (2000) Development , vol.127 , pp. 2227-2238
    • Tada, M.1    Smith, J.C.2
  • 91
    • 0043234810 scopus 로고    scopus 로고
    • Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity
    • Westfall, T. A. et al.Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity. J. Cell Biol. 162, 889-898 (2003).
    • (2003) J. Cell Biol , vol.162 , pp. 889-898
    • Westfall, T.A.1
  • 92
    • 0031938970 scopus 로고    scopus 로고
    • Mutations in the cadherin superfamily member gene dachsous cause a tissue polarity phenotype by altering frizzled signaling
    • Adler, P. N., Charlton, J. & Liu, J. Mutations in the cadherin superfamily member gene dachsous cause a tissue polarity phenotype by altering frizzled signaling. Development 125, 959-68 (1998).
    • (1998) Development , vol.125 , pp. 959-968
    • Adler, P.N.1    Charlton, J.2    Liu, J.3
  • 93
    • 0037162283 scopus 로고    scopus 로고
    • Developmental compartments and planar polarity in Drosophila
    • Casal, J., Struhl, G. & Lawrence, P. A. Developmental compartments and planar polarity in Drosophila. Curr. Biol. 12, 1189-1198 (2002).
    • (2002) Curr. Biol , vol.12 , pp. 1189-1198
    • Casal, J.1    Struhl, G.2    Lawrence, P.A.3
  • 94
    • 0036333367 scopus 로고    scopus 로고
    • Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen
    • Lawrence, P. A., Casal, J. & Struhl, G. Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen. Development 129, 2749-2760 (2002).
    • (2002) Development , vol.129 , pp. 2749-2760
    • Lawrence, P.A.1    Casal, J.2    Struhl, G.3
  • 95
    • 33845288905 scopus 로고    scopus 로고
    • Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity
    • Casal, J., Lawrence, P. A. & Struhl, G. Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development 133, 4561-4572 (2006).
    • (2006) Development , vol.133 , pp. 4561-4572
    • Casal, J.1    Lawrence, P.A.2    Struhl, G.3
  • 96
    • 0344413477 scopus 로고    scopus 로고
    • Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    • Wong, H.-C. et al.Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol. Cell 12, 1251-1260 (2003).
    • (2003) Mol. Cell , vol.12 , pp. 1251-1260
    • Wong, H.-C.1
  • 97
    • 0032529161 scopus 로고    scopus 로고
    • Differential requirement of Dishevelled provides signaling specificity in the Wingless and planar cell polarity signaling pathways
    • Axelrod, J. D., Miller, J. R., Shulman, J. M., Moon, R. T. & Perrimon, N. Differential requirement of Dishevelled provides signaling specificity in the Wingless and planar cell polarity signaling pathways. Genes Dev. 12, 2610-2622 (1998).
    • (1998) Genes Dev , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 98
    • 0034625641 scopus 로고    scopus 로고
    • Signaling specificity by Frizzled receptors in Drosophila
    • Boutros, M., Mihaly, J., Bouwmeester, T. & Mlodzik, M. Signaling specificity by Frizzled receptors in Drosophila. Science 288, 1825-1828 (2000).
    • (2000) Science , vol.288 , pp. 1825-1828
    • Boutros, M.1    Mihaly, J.2    Bouwmeester, T.3    Mlodzik, M.4
  • 99
    • 0242690871 scopus 로고    scopus 로고
    • Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis
    • Rothbacher, U. et al.Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis. EMBO J. 19, 1010-1022 (2000).
    • (2000) EMBO J , vol.19 , pp. 1010-1022
    • Rothbacher, U.1
  • 100
    • 0033868542 scopus 로고    scopus 로고
    • Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
    • Djiane, A., Riou, J., Umbhauer, M., Boucaut, J. & Shi, D. Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 127, 3091-100 (2000).
    • (2000) Development , vol.127 , pp. 3091-3100
    • Djiane, A.1    Riou, J.2    Umbhauer, M.3    Boucaut, J.4    Shi, D.5
  • 101
    • 0024972122 scopus 로고
    • Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • Vinson, C. R., Conover, S. & Adler, P. N. A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature 338, 263-264 (1989).
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.A.3
  • 102
    • 0036812502 scopus 로고    scopus 로고
    • Frizzled-3 is required for the development of major fiber tracts in the rostral CNS
    • Wang, Y., Thekdi, N., Smallwood, P. M., Macke, J. P. & Nathans, J. Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. J. Neurosci. 22, 8563-8573 (2002).
    • (2002) J. Neurosci , vol.22 , pp. 8563-8573
    • Wang, Y.1    Thekdi, N.2    Smallwood, P.M.3    Macke, J.P.4    Nathans, J.5
  • 103
    • 0029145518 scopus 로고
    • frizzled regulates mirror-symmetric pattern formation in the Drosophila eye
    • Zheng, L., Zhang, J. & Carthew, R. W. frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. Development 121, 3045-3055 (1995).
    • (1995) Development , vol.121 , pp. 3045-3055
    • Zheng, L.1    Zhang, J.2    Carthew, R.W.3
  • 104
    • 0032504052 scopus 로고    scopus 로고
    • Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    • Boutros, M., Paricio, N., Strutt, D. I. & Mlodzik, M. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94, 109-118 (1998).
    • (1998) Cell , vol.94 , pp. 109-118
    • Boutros, M.1    Paricio, N.2    Strutt, D.I.3    Mlodzik, M.4
  • 105
    • 0027954477 scopus 로고
    • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal
    • Klingensmith, J., Nusse, R. & Perrimon, N. The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev. 8, 118-130 (1994).
    • (1994) Genes Dev , vol.8 , pp. 118-130
    • Klingensmith, J.1    Nusse, R.2    Perrimon, N.3
  • 106
    • 0029033080 scopus 로고
    • Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled
    • Sokol, S. Y., Klingensmith, J., Perrimon, N. & Itoh, K. Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121, 3487 (1995).
    • (1995) Development , vol.121 , pp. 3487
    • Sokol, S.Y.1    Klingensmith, J.2    Perrimon, N.3    Itoh, K.4
  • 107
    • 0027944513 scopus 로고
    • Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled
    • Sussman, D. J. et al.Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev. Biol. 166, 73-86 (1994).
    • (1994) Dev. Biol , vol.166 , pp. 73-86
    • Sussman, D.J.1
  • 108
    • 0041677608 scopus 로고    scopus 로고
    • Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish
    • Carreira-Barbosa, F. et al.Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development 130, 4037-4046 (2003).
    • (2003) Development , vol.130 , pp. 4037-4046
    • Carreira-Barbosa, F.1
  • 109
    • 0033200334 scopus 로고    scopus 로고
    • The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs
    • Gubb, D. et al.The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. Genes Dev. 13, 2315-2327 (1999).
    • (1999) Genes Dev , vol.13 , pp. 2315-2327
    • Gubb, D.1
  • 110
    • 0037446876 scopus 로고    scopus 로고
    • The prickle-related gene in vertebrates is essential for gastrulation cell movements
    • Takeuchi, M. et al.The prickle-related gene in vertebrates is essential for gastrulation cell movements. Curr. Biol. 13, 674-679 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 674-679
    • Takeuchi, M.1
  • 111
    • 0344373791 scopus 로고    scopus 로고
    • Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements
    • Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H. & Moon, R. T. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr. Biol. 13, 680-685 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 680-685
    • Veeman, M.T.1    Slusarski, D.C.2    Kaykas, A.3    Louie, S.H.4    Moon, R.T.5
  • 112
    • 0036079896 scopus 로고    scopus 로고
    • The planar cell polarity gene Strabismus regulates convergence and extension and neural fold closure in Xenopus
    • Goto, T. & Keller, R. The planar cell polarity gene Strabismus regulates convergence and extension and neural fold closure in Xenopus. Dev. Biol. 247, 165-181 (2002).
    • (2002) Dev. Biol , vol.247 , pp. 165-181
    • Goto, T.1    Keller, R.2
  • 113
    • 0036047390 scopus 로고    scopus 로고
    • Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements
    • Jessen, J. R. et al.Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nature Cell Biol. 4, 610-615 (2002).
    • (2002) Nature Cell Biol , vol.4 , pp. 610-615
    • Jessen, J.R.1
  • 114
    • 0031688426 scopus 로고    scopus 로고
    • Van Gogh: A new Drosophila tissue polarity gene
    • Taylor, J., Abramova, N., Charlton, J. & Adler, P. N. Van Gogh: a new Drosophila tissue polarity gene. Genetics 150, 199-210 (1998).
    • (1998) Genetics , vol.150 , pp. 199-210
    • Taylor, J.1    Abramova, N.2    Charlton, J.3    Adler, P.N.4
  • 115
    • 0035408009 scopus 로고    scopus 로고
    • The Ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization
    • Feiguin, F., Hannus, M., Mlodzik, M. & Eaton, S. The Ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Developmental Cell 1, 93-101 (2001).
    • (2001) Developmental Cell , vol.1 , pp. 93-101
    • Feiguin, F.1    Hannus, M.2    Mlodzik, M.3    Eaton, S.4
  • 116
    • 0037102507 scopus 로고    scopus 로고
    • The ankyrin repeat protein Diversin recruits Casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
    • Schwarz-Romond, T. et al.The ankyrin repeat protein Diversin recruits Casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev. 16, 2073-2084 (2002).
    • (2002) Genes Dev , vol.16 , pp. 2073-2084
    • Schwarz-Romond, T.1
  • 117
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons, M. et al.Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nature Genet. 37, 537-543 (2005).
    • (2005) Nature Genet , vol.37 , pp. 537-543
    • Simons, M.1
  • 118
    • 0345736924 scopus 로고    scopus 로고
    • The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing
    • Lee, H. & Adler, P. N. The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing. Mech. Dev. 121, 37-49 (2004).
    • (2004) Mech. Dev , vol.121 , pp. 37-49
    • Lee, H.1    Adler, P.N.2
  • 119
    • 12444329708 scopus 로고    scopus 로고
    • Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea
    • Dabdoub, A. et al.Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea. Development 130, 2375-2384 (2003).
    • (2003) Development , vol.130 , pp. 2375-2384
    • Dabdoub, A.1
  • 120
    • 0038750629 scopus 로고    scopus 로고
    • Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
    • Ohkawara, B., Yamamoto, T. S., Tada, M. & Ueno, N. Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 130, 2129-2138 (2003).
    • (2003) Development , vol.130 , pp. 2129-2138
    • Ohkawara, B.1    Yamamoto, T.S.2    Tada, M.3    Ueno, N.4
  • 121
    • 0035434453 scopus 로고    scopus 로고
    • The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
    • Topczewski, J. et al.The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev. Cell 1, 251-264 (2001).
    • (2001) Dev. Cell , vol.1 , pp. 251-264
    • Topczewski, J.1
  • 122
    • 3042845655 scopus 로고    scopus 로고
    • PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates
    • Lu, X. et al.PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 430, 93-98 (2004).
    • (2004) Nature , vol.430 , pp. 93-98
    • Lu, X.1
  • 123
    • 0029918895 scopus 로고    scopus 로고
    • The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein
    • Park, W. J., Liu, J., Sharp, E. J. & Adler, P. N. The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein. Development 122, 961-969 (1996).
    • (1996) Development , vol.122 , pp. 961-969
    • Park, W.J.1    Liu, J.2    Sharp, E.J.3    Adler, P.N.4
  • 124
    • 0344718656 scopus 로고    scopus 로고
    • The inturned protein of Drosophila melanogaster is a cytoplasmic protein located at the cell periphery in wing cells
    • Yun, U. J. et al.The inturned protein of Drosophila melanogaster is a cytoplasmic protein located at the cell periphery in wing cells. Dev. Genet. 25, 297-305 (1999).
    • (1999) Dev. Genet , vol.25 , pp. 297-305
    • Yun, U.J.1
  • 125
    • 0030776197 scopus 로고    scopus 로고
    • Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein
    • Collier, S. & Gubb, D. Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein. Development 124, 4029-4037 (1997).
    • (1997) Development , vol.124 , pp. 4029-4037
    • Collier, S.1    Gubb, D.2
  • 126
    • 9244243685 scopus 로고    scopus 로고
    • Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins
    • Adler, P. N., Zhu, C. & Stone, D. Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins. Curr. Biol. 14, 2046-51 (2004).
    • (2004) Curr. Biol , vol.14 , pp. 2046-2051
    • Adler, P.N.1    Zhu, C.2    Stone, D.3
  • 127
    • 18844445641 scopus 로고    scopus 로고
    • The WD40 repeat protein Fritz links cytoskeletal planar polarity to Frizzled subcellular localization in the Drosophila epidermis
    • Collier, S., Lee, H., Burgess, R. & Adler, P. The WD40 repeat protein Fritz links cytoskeletal planar polarity to Frizzled subcellular localization in the Drosophila epidermis. Genetics 169, 2035-2045 (2005).
    • (2005) Genetics , vol.169 , pp. 2035-2045
    • Collier, S.1    Lee, H.2    Burgess, R.3    Adler, P.4
  • 128
    • 0027361185 scopus 로고
    • Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells
    • Wong, L. L. & Adler, P. N. Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells. J. Cell Biol. 123, 209-221 (1993).
    • (1993) J. Cell Biol , vol.123 , pp. 209-221
    • Wong, L.L.1    Adler, P.N.2
  • 129
    • 0030458493 scopus 로고    scopus 로고
    • Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila
    • Eaton, S., Wepf, R. & Simons, K. Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. J. Cell Biol. 135, 1277-1289 (1996).
    • (1996) J. Cell Biol , vol.135 , pp. 1277-1289
    • Eaton, S.1    Wepf, R.2    Simons, K.3
  • 130
    • 0034710614 scopus 로고    scopus 로고
    • Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye
    • Fanto, M., Weber, U., Strutt, D. I. & Mlodzik, M. Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr. Biol. 10, 979-988 (2000).
    • (2000) Curr. Biol , vol.10 , pp. 979-988
    • Fanto, M.1    Weber, U.2    Strutt, D.I.3    Mlodzik, M.4
  • 131
    • 0037439138 scopus 로고    scopus 로고
    • Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
    • Habas, R., Dawid, I. B. & He, X. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev. 17, 295-309 (2003).
    • (2003) Genes Dev , vol.17 , pp. 295-309
    • Habas, R.1    Dawid, I.B.2    He, X.3
  • 132
    • 0030917227 scopus 로고    scopus 로고
    • The role of RhoA in tissue polarity and Frizzled signalling
    • Strutt, D. I., Weber, U. & Mlodzik, M. The role of RhoA in tissue polarity and Frizzled signalling. Nature 387, 292-295 (1997).
    • (1997) Nature , vol.387 , pp. 292-295
    • Strutt, D.I.1    Weber, U.2    Mlodzik, M.3
  • 133
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
    • Habas, R., Kato, Y. & He, X. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107, 843-854 (2001).
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1    Kato, Y.2    He, X.3
  • 134
    • 0037966282 scopus 로고    scopus 로고
    • Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation
    • Tahinci, E. & Symes, K. Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation. Dev. Biol. 259, 318-335 (2003).
    • (2003) Dev. Biol , vol.259 , pp. 318-335
    • Tahinci, E.1    Symes, K.2
  • 135
    • 33645547390 scopus 로고    scopus 로고
    • The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton
    • Matusek, T. et al.The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton. Development 133, 957-966 (2006).
    • (2006) Development , vol.133 , pp. 957-966
    • Matusek, T.1
  • 136
    • 0033200204 scopus 로고    scopus 로고
    • The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling
    • Paricio, N., Feiguin, F., Boutros, M., Eaton, S. & Mlodzik, M. The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling. EMBO J. 18, 4669-4678 (1999).
    • (1999) EMBO J , vol.18 , pp. 4669-4678
    • Paricio, N.1    Feiguin, F.2    Boutros, M.3    Eaton, S.4    Mlodzik, M.5
  • 137
    • 0032843487 scopus 로고    scopus 로고
    • Genetic analysis of cadherin function in animal morphogenesis
    • Tepass, U. Genetic analysis of cadherin function in animal morphogenesis. Curr. Opin. Cell Biol. 11, 540-548 (1999).
    • (1999) Curr. Opin. Cell Biol , vol.11 , pp. 540-548
    • Tepass, U.1


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