Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines

Journal of Lipid Research

Volumn 39, Issue 6, 1998, Pages 1220-1230

  Navasa, Miguel ^a   Gordon, David A ^b   Hariharan, Narayanan ^b   Jamil, Haris ^b   Shigenaga, Judy K ^a   Moser, Arthur ^a   Fiers, Walter ^c   Pollock, Allan ^a   Grunfeld, Carl ^a   Feingold, Kenneth R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

Activating protein 1; Apolipoprotein B; Hepatic nuclear factor 1; Interleukins; Tumor necrosis factor

Indexed keywords

CARRIER PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; GENE DELETION; GENE EXPRESSION REGULATION; GENE STRUCTURE; LIPID METABOLISM; LIPOLYSIS; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

ANIMALS; APOLIPOPROTEINS B; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CRICETINAE; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; KINETICS; LIPOPOLYSACCHARIDES; LIVER NEOPLASMS; MALE; MESOCRICETUS; MICROSOMES, LIVER; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 15144345947     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Liao, W., and C. H. Floren. 1993. Endotoxin, cytokines, and hyperlipidemia. Scand. J. Gastroenterol. 28: 97-103.
2. Hardardottir, I., C. Grunfeld, and K. R. Feingold. 1994. Effects of endotoxin and cytokines on lipid metabolism. Curr. Opin. Lipidol. 5: 207-215.
3. Hardardottir, I., C. Grunfeld, and K. R. Feingold. 1995. Effects of endotoxin on lipid metabolism. Biochem. Soc. Trans. 23: 1013-1018.
4. Kishimoto, T., T. Taga, and S. Akira. 1994. Cytokine signal transduction. Cell. 76: 253-262.
5. Baumann, H., K. R. Prowse, S. Marinkovic, K. A. Won, and G. P. Jahreis. 1989. Stimulation of hepatic acute phase response by cytokines and glucocorticoids. Ann. NY Acad. Sci. 557: 280-295.
6. Gregg, R. E., and J. R. Wetterau. 1994. The molecular basis of abeta-lipoproteinemia. Curr. Opin. Lipidol. 5: 81-86.
7. Sharp, D., L. Blinderman, K. A. Coms, B. Kienze, B. Ricci, K. Wager-Smith, C. M. Gil, C. W. Turk, M. E. Bouma, D. J. Rader, L. P. Aggerbeck, R. E. Gregg, D. A. Gordon, and J. R. Wetterau. 1993. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature. 365: 65-69.
8. Gordon D. A., H. Jamil, D. Sharp, D. Mullaney, Z. Yao, R. E. Gregg, and J. Wetterau. 1994. Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability. Proc. Natl Acad. Sci. USA. 91: 7628-7632.
9. Hagan, D. L., B. Kienzle, H. Jamil, and N. Hariharan. 1994. Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators. J. Biol. Chem. 269: 28737-28744.
10. Lin M. C. M., D. Gordon, and J. R. Wetterau. 1995. Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression. J. Lipid Res. 36: 1073-1081.
11. Feingold, K. R., I. Hardardottir, R. Memon, E. J. T. Krul, A. H. Moser, J. M. Taylor, and C. Grunfeld. 1993. The effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters. J. Lipid Res. 34: 2147-2158.
12. Hardardottir, I., A. H. Moser, R. A. Memon, C. Grunfeld, and K. R. Feingold. 1994. Effects of TNF, IL-1 and the combination of both cytokines on cholesterol metabolism in Syrian hamsters. Cytokine Res. 13: 161-166.
13. Morrow, J. F., R. J. Stearman, C. G. Peltzman, and D. A. Potter. 1981 Induction of hepatic synthesis of serum amyloid A protein and actin. Proc. Natl. Acad. Sci. USA. 78: 4718-4722.
14. Memon, R. A., K. R. Feingold, A. H. Moser, J. Fuller, and Grunfeld, C. 1998. Regulation of fatty acid transport protein and fatty acid translocase mRNA levels by endotoxin and cytokines. Am. J. Physiol. 37:E210-E217.
15. Marshall, M. K., W. Doerrler, K. R. Feingold, and C. Grunfeld. 1994. Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes. Endocrinology. 135: 141-147.
16. Wetterau, J. R., L. P. Aggerbeck, M. E. Bouma, C. Eisenberg, A. Munck, M. Hermier, J. Schmitz, G. Gay, D. J. Radar, and R. E. Gregg. 1992. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science. 258: 999-1001.
17. Sambrook, J., E. F. Fritsch, and T. Manietis. 1989. Molecular Cloning, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 16.66-16.67.
18. Sipe, J. D., H. Rokita, and F. C. de Beer. 1993. Acute Phase Proteins. Molecular Biology, Biochemistry and Clinical Applications. A. Mackiewicz, I. Kushner, and H. Baumann, editors. CRC Press, Boca Raton, FL. Chapter 28: 511-526.
19. Burke, P. A., M. Drotar, M. Luo, M. Yaffe, and R. A. Forse. 1994. Rapid modulation of liver-specific transcription factors after injury. Surgery. 116:285-293.
20. Pietrangelo, A., and D. A. Shafritz. 1994. Homeostatic regulation of hepatocyte nuclear transcription factor 1 expression in cultured hepatoma cells. Proc. Natl. Acad. Sci. USA. 91: 182-186.
21. Kushner, I. 1982. The phenomenon of the acute phase response. Ann. NY Acad. Sci. 389: 39-48.
22. Hardardottir, I., S. T. Knitake, A. H. Moser, W. Doerrler, J. H. Rapp, C. Grunfeld, and K. R. Feingold, 1994. Endotoxin and cytokines increase hepatic mRNA levels and serum concentrations of apolipoprotein J (Clusterin) in Syrian hamsters. J. Clin. Invest. 94: 1304-1309.
23. Feingold, K. R., D. K. Spady, A. S. Pollock, A. H. Moser, and C. Grunfeld. 1996. Endotoxin, TNF, and IL-1 decrease cholesterol 7α-hydroxylase mRNA levels and activity. J. Lipid Res. 37: 223-228.
24. Hardardottir, I., A. H. Moser, J. Fuller, C. Fielding, K. R. Feingold, and C. Grunfeld. 1996. Endotoxin and cytokines decrease serum levels and extrahepatic protein and mRNA levels of cholesteryl ester transfer protein in Syrian hamsters. J. Clin. Invest. 97: 2585-2592.
25. Ly, H., O. L. Francone, C. J. Fielding, J. K. Shigenaga, A. H. Moser, C. Grunfeld, and K. R. Feingold. 1995. Endotoxin and TNF lead to reduced plasma LCAT activity and decreased hepatic LCAT mRNA levels in Syrian hamsters. J. Lipid Res. 36: 1254-1263.
26. Berg, D. T., D. S. Calnek, and B. W. Grinnell. 1996. Trans-repressor BEF-1 phosphorylation. A potential control mechanism for human apoE gene regulation. J. Biol. Chem. 271: 4589-4592.
27. Baumann, H., G. P. Jahreis, K. K. Morella, W. Kwangrai, S. C. Pruitt, V. E. Jones, and K. R. Prowse. 1991. Transcriptional regulation through cytokine and glucocorticoid response elements of rat acute phase plasma protein genes by C/EBP and JunB. J. Biol. Chem. 266: 20390-20399.
28. Hattori, M., A. Tugores, J. K. Westwick, L. Veloz, A. L. Leffert, M. Karin, and D. A. Brenner. 1993. Activation of activating protein 1 during hepatic acute phase response. Am. J. Physiol. 27: G95-G103.
29. Muegge, K., M. Vila, G. L. Gusella, T. Musso, P. Herrlich, B. Stein, and S. K. Durum. 1993. Interleukin 1 induction of the c-jun promoter. Proc. Natl. Acad. Sci. USA. 90: 7054-7058.
30. Beauchamp, R. D., J. Papaconstantinou, A. M. Henderson, H. M. Sheng, C. M. Townsend, Jr., and J. C. Thompson. 1994. Activation of hepatic proliferation-associated transcription factors by lipopolysaccharide. Surgery. 116: 367-377.
31. Hertz, R., M. Seckbach, M. M. Zakin, and J. Bar-Tana. 1996. Transcriptional suppression of the transferrin gene by hypolipidemic peroxisome proliferators. J. Biol. Chem. 271: 218-224.
32. Aldred, A. R., and G. Schreiber. 1993. The negative acute phase proteins. In Acute Phase Proteins. Chapter 2. A. Mackiewicz, I. Kushner, and H. Baumann, editors. CRC Press, Boca Raton, FL. 21-37.