메뉴 건너뛰기




Volumn 24, Issue 10, 2009, Pages 1343-1355

The role of krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells

Author keywords

ES cells; iPS cells; KLF; Reprogramming; Somatic cells

Indexed keywords

IPS;

EID: 70349449352     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (79)

References (163)
  • 1
    • 0034532401 scopus 로고    scopus 로고
    • Positive- and negative-acting Krüppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo
    • Adam P.J., Regan C.P., Hautmann M.B. and Owens G.K. (2000). Positive- and negative-acting Krüppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo. J. Biol. Chem. 275, 37798-37806.
    • (2000) J. Biol. Chem , vol.275 , pp. 37798-37806
    • Adam, P.J.1    Regan, C.P.2    Hautmann, M.B.3    Owens, G.K.4
  • 2
    • 33751208617 scopus 로고    scopus 로고
    • Reprogramming somatic cells into stem cells
    • Alberio R., Campbell K.H. and Johnson A.D. (2006). Reprogramming somatic cells into stem cells. Reproduction 132, 709-720.
    • (2006) Reproduction , vol.132 , pp. 709-720
    • Alberio, R.1    Campbell, K.H.2    Johnson, A.D.3
  • 4
    • 0028784790 scopus 로고
    • Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: Identification of a new multigene family
    • Anderson K.P., Kern C.B., Crable S.C. and Lingrel J.B. (1995). Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family. Mol. Cell. Biol. 15, 5957-5965.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 5957-5965
    • Anderson, K.P.1    Kern, C.B.2    Crable, S.C.3    Lingrel, J.B.4
  • 6
    • 1842425769 scopus 로고    scopus 로고
    • Intestinal tumor progression is associated with altered function of KLF5
    • Bateman N.W., Tan D., Pestell R.G., Black J.D. and Black A.R. (2004). Intestinal tumor progression is associated with altered function of KLF5. J. Biol. Chem. 279, 12093-12101.
    • (2004) J. Biol. Chem , vol.279 , pp. 12093-12101
    • Bateman, N.W.1    Tan, D.2    Pestell, R.G.3    Black, J.D.4    Black, A.R.5
  • 7
    • 41449116010 scopus 로고    scopus 로고
    • Transcriptional regulation of adipogenesis by KLF4
    • Birsoy K., Chen Z. and Friedman J. (2008). Transcriptional regulation of adipogenesis by KLF4. Cell Metab. 7, 339-347.
    • (2008) Cell Metab , vol.7 , pp. 339-347
    • Birsoy, K.1    Chen, Z.2    Friedman, J.3
  • 8
    • 0034929708 scopus 로고    scopus 로고
    • Sp1 and kruppellike factor family of transcription factors in cell growth regulation and cancer
    • Black A.R., Black J.D. and Azizkhan-Clifford J. (2001). Sp1 and kruppellike factor family of transcription factors in cell growth regulation and cancer. J. Cell Physiol. 188, 143-160.
    • (2001) J. Cell Physiol , vol.188 , pp. 143-160
    • Black, A.R.1    Black, J.D.2    Azizkhan-Clifford, J.3
  • 9
    • 0028812689 scopus 로고
    • Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation
    • Blok L.J., Grossmann M.E., Perry J.E. and Tindall D.J. (1995). Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation. Mol. Endocrinol. 9, 1610-1620.
    • (1995) Mol. Endocrinol , vol.9 , pp. 1610-1620
    • Blok, L.J.1    Grossmann, M.E.2    Perry, J.E.3    Tindall, D.J.4
  • 10
    • 0034623068 scopus 로고    scopus 로고
    • The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1
    • Brembeck F.H. and Rustgi A.K. (2000). The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1. J. Biol. Chem. 275, 28230-28239.
    • (2000) J. Biol. Chem , vol.275 , pp. 28230-28239
    • Brembeck, F.H.1    Rustgi, A.K.2
  • 11
    • 48849110380 scopus 로고    scopus 로고
    • Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts
    • Bru T., Clarke C., McGrew M.J., Sang H.M., Wilmut I. and Blow J.J. (2008). Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts. Exp. Cell Res. 314, 2634-2642.
    • (2008) Exp. Cell Res , vol.314 , pp. 2634-2642
    • Bru, T.1    Clarke, C.2    McGrew, M.J.3    Sang, H.M.4    Wilmut, I.5    Blow, J.J.6
  • 13
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I., Colby D., Robertson M., Nichols J., Lee S., Tweedie S. and Smith A. (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655.
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 14
    • 9644277225 scopus 로고    scopus 로고
    • Alltrans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5
    • Chanchevalap S., Nandan M.O., Merlin D. and Yang V.W. (2004). Alltrans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5. FEBS Lett. 578, 99-105.
    • (2004) FEBS Lett , vol.578 , pp. 99-105
    • Chanchevalap, S.1    Nandan, M.O.2    Merlin, D.3    Yang, V.W.4
  • 15
    • 0037179848 scopus 로고    scopus 로고
    • A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
    • Chen C., Bhalala H.V., Qiao H. and Dong J.T. (2002). A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 21, 6567-6572.
    • (2002) Oncogene , vol.21 , pp. 6567-6572
    • Chen, C.1    Bhalala, H.V.2    Qiao, H.3    Dong, J.T.4
  • 16
    • 0037405689 scopus 로고    scopus 로고
    • KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer
    • Chen C., Bhalala H.V., Vessella R.L. and Dong J.T. (2003a). KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer. Prostate 55, 81-88.
    • (2003) Prostate , vol.55 , pp. 81-88
    • Chen, C.1    Bhalala, H.V.2    Vessella, R.L.3    Dong, J.T.4
  • 18
    • 0347717672 scopus 로고    scopus 로고
    • Dedifferentiation of lineage-committed cells by a small molecule
    • Chen S., Zhang Q., Wu X., Schultz P.G. and Ding S. (2004). Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc. 126, 410-411.
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 410-411
    • Chen, S.1    Zhang, Q.2    Wu, X.3    Schultz, P.G.4    Ding, S.5
  • 19
    • 0035839554 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen X., Johns D.C., Geiman D.E., Marban E., Dang D.T., Hamlin G., Sun R. and Yang V.W. (2001). Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 276, 30423-30428.
    • (2001) J. Biol. Chem , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3    Marban, E.4    Dang, D.T.5    Hamlin, G.6    Sun, R.7    Yang, V.W.8
  • 20
    • 0037459050 scopus 로고    scopus 로고
    • Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation
    • Chen X., Whitney E.M., Gao S.Y. and Yang V.W. (2003b). Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. J. Mol. Biol. 326, 665-677.
    • (2003) J. Mol. Biol , vol.326 , pp. 665-677
    • Chen, X.1    Whitney, E.M.2    Gao, S.Y.3    Yang, V.W.4
  • 21
    • 45349087465 scopus 로고    scopus 로고
    • Nuclear Krüppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis
    • Chen Y.J., Wu C.Y., Chang C.C., Ma C.J., Li M.C. and Chen C.M. (2008). Nuclear Krüppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis. Cancer Biol. Ther. 7, 777-782.
    • (2008) Cancer Biol. Ther , vol.7 , pp. 777-782
    • Chen, Y.J.1    Wu, C.Y.2    Chang, C.C.3    Ma, C.J.4    Li, M.C.5    Chen, C.M.6
  • 22
    • 16644366016 scopus 로고    scopus 로고
    • Cell and tissue specific expression of human Krüppel-like transcription factors in human ocular surface
    • Chiambaretta F., De Graeve F., Turet G., Marceau G., Gain P., Dastugue B., Rigal D. and Sapin V. (2004). Cell and tissue specific expression of human Krüppel-like transcription factors in human ocular surface. Mol. Vis. 10, 901-909.
    • (2004) Mol. Vis , vol.10 , pp. 901-909
    • Chiambaretta, F.1    de Graeve, F.2    Turet, G.3    Marceau, G.4    Gain, P.5    Dastugue, B.6    Rigal, D.7    Sapin, V.8
  • 24
    • 0033104158 scopus 로고    scopus 로고
    • A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells
    • Conkright M.D., Wani M.A., Anderson K.P. and Lingrel J.B. (1999). A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells. Nucleic Acids Res. 27, 1263-1270.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1263-1270
    • Conkright, M.D.1    Wani, M.A.2    Anderson, K.P.3    Lingrel, J.B.4
  • 25
    • 0032475869 scopus 로고    scopus 로고
    • Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth
    • Cook T., Gebelein B., Mesa K., Mladek A. and Urrutia R. (1998). Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth. J. Biol. Chem. 273, 25929-25936.
    • (1998) J. Biol. Chem , vol.273 , pp. 25929-25936
    • Cook, T.1    Gebelein, B.2    Mesa, K.3    Mladek, A.4    Urrutia, R.5
  • 26
    • 23944457397 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • Cowan C.A., Atienza J., Melton D.A. and Eggan K. (2005). Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373.
    • (2005) Science , vol.309 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 27
    • 43549107895 scopus 로고    scopus 로고
    • Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines
    • Cullingford T.E., Butler M.J., Marshall A.K., Tham el L., Sugden P.H. and Clerk A. (2008). Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Biochim. Biophys. Acta 1783, 1229-1236.
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 1229-1236
    • Cullingford, T.E.1    Butler, M.J.2    Marshall, A.K.3    el Tham, L.4    Sugden, P.H.5    Clerk, A.6
  • 28
    • 0034617495 scopus 로고    scopus 로고
    • Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients
    • Dang D.T., Bachman K.E., Mahatan C.S., Dang L.H., Giardiello F.M. and Yang V.W. (2000a). Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients. FEBS Lett. 476, 203-207.
    • (2000) FEBS Lett , vol.476 , pp. 203-207
    • Dang, D.T.1    Bachman, K.E.2    Mahatan, C.S.3    Dang, L.H.4    Giardiello, F.M.5    Yang, V.W.6
  • 29
    • 0034532675 scopus 로고    scopus 로고
    • The biology of the mammalian Krüppel-like family of transcription factors
    • Dang D.T., Pevsner J. and Yang V.W. (2000b). The biology of the mammalian Krüppel-like family of transcription factors. Int. J. Biochem. Cell Biol. 32, 1103-1121.
    • (2000) Int. J. Biochem. Cell Biol , vol.32 , pp. 1103-1121
    • Dang, D.T.1    Pevsner, J.2    Yang, V.W.3
  • 30
    • 0036639383 scopus 로고    scopus 로고
    • Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene
    • Dang D.T., Zhao W., Mahatan C.S., Geiman D.E. and Yang V.W. (2002). Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene. Nucleic Acids Res. 30, 2736-2741.
    • (2002) Nucleic Acids Res , vol.30 , pp. 2736-2741
    • Dang, D.T.1    Zhao, W.2    Mahatan, C.S.3    Geiman, D.E.4    Yang, V.W.5
  • 32
    • 33144463121 scopus 로고    scopus 로고
    • Cdx2 gene expression and trophectoderm lineage specification in mouse embryos
    • Deb K., Sivaguru M., Yong H.Y. and Roberts R.M. (2006). Cdx2 gene expression and trophectoderm lineage specification in mouse embryos. Science 311, 992-996.
    • (2006) Science , vol.311 , pp. 992-996
    • Deb, K.1    Sivaguru, M.2    Yong, H.Y.3    Roberts, R.M.4
  • 33
    • 57449095953 scopus 로고    scopus 로고
    • Efficient genetic reprogramming of unmodified somatic neural progenitors uncovers the essential requirement of Oct4 and Klf4
    • In Press
    • Di Stefano B., Prigione A. and Broccoli V. (2008). Efficient genetic reprogramming of unmodified somatic neural progenitors uncovers the essential requirement of Oct4 and Klf4. Stem Cells Dev. (In Press).
    • (2008) Stem Cells Dev
    • di Stefano, B.1    Prigione, A.2    Broccoli, V.3
  • 35
    • 3042744026 scopus 로고    scopus 로고
    • A role for chemistry in stem cell biology
    • Ding S. and Schultz P.G. (2004). A role for chemistry in stem cell biology. Nat. Biotechnol. 22, 833-840.
    • (2004) Nat. Biotechnol , vol.22 , pp. 833-840
    • Ding, S.1    Schultz, P.G.2
  • 36
    • 0035740250 scopus 로고    scopus 로고
    • Chromosomal deletions and tumor suppressor genes in prostate cancer
    • Dong J.T. (2001). Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Metastasis Rev. 20, 173-193.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 173-193
    • Dong, J.T.1
  • 37
    • 57649121591 scopus 로고    scopus 로고
    • SUMOylation regulates nuclear localization of Krüppel-like factor 5
    • Du J.X., Bialkowska A.B., McConnell B.B. and Yang V.W. (2008). SUMOylation regulates nuclear localization of Krüppel-like factor 5. J. Biol. Chem. 283, 31991-32002.
    • (2008) J. Biol. Chem , vol.283 , pp. 31991-32002
    • Du, J.X.1    Bialkowska, A.B.2    McConnell, B.B.3    Yang, V.W.4
  • 38
    • 33947520145 scopus 로고    scopus 로고
    • Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5
    • Du J.X., Yun C.C., Bialkowska A. and Yang V.W. (2007). Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5. J. Biol. Chem. 282, 4782-4793.
    • (2007) J. Biol. Chem , vol.282 , pp. 4782-4793
    • Du, J.X.1    Yun, C.C.2    Bialkowska, A.3    Yang, V.W.4
  • 39
    • 34249890186 scopus 로고    scopus 로고
    • Developmental reprogramming after chromosome transfer into mitotic mouse zygotes
    • Egli D., Rosains J., Birkhoff G. and Eggan K. (2007). Developmental reprogramming after chromosome transfer into mitotic mouse zygotes. Nature 447, 679-685.
    • (2007) Nature , vol.447 , pp. 679-685
    • Egli, D.1    Rosains, J.2    Birkhoff, G.3    Eggan, K.4
  • 41
    • 55049122748 scopus 로고    scopus 로고
    • Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression
    • Eminli S., Utikal J., Arnold K., Jaenisch R. and Hochedlinger K. (2008). Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem Cells 26, 2467-2474.
    • (2008) Stem Cells , vol.26 , pp. 2467-2474
    • Eminli, S.1    Utikal, J.2    Arnold, K.3    Jaenisch, R.4    Hochedlinger, K.5
  • 42
    • 0029923977 scopus 로고    scopus 로고
    • Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways
    • Ernst M., Oates A. and Dunn A.R. (1996). Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways. J. Biol. Chem. 271, 30136-30143.
    • (1996) J. Biol. Chem , vol.271 , pp. 30136-30143
    • Ernst, M.1    Oates, A.2    Dunn, A.R.3
  • 43
    • 23144448924 scopus 로고    scopus 로고
    • Ethical sourcing of human embryonic stem cells-- rational solutions?
    • Evans M. (2005). Ethical sourcing of human embryonic stem cells-- rational solutions? Nat Rev Mol. Cell. Biol. 6, 663-667.
    • (2005) Nat Rev Mol. Cell. Biol , vol.6 , pp. 663-667
    • Evans, M.1
  • 47
    • 0033057439 scopus 로고    scopus 로고
    • Oncogene expression cloning by retroviral transducti on of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF
    • Foster K.W., Ren S., Louro I.D., Lobo-Ruppert S.M., McKie-Bell P., Grizzle W., Hayes M.R., Broker T.R., Chow L.T. and Ruppert J.M. (1999). Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF. Cell Growth Differ. 10, 423-434.
    • (1999) Cell Growth Differ , vol.10 , pp. 423-434
    • Foster, K.W.1    Ren, S.2    Louro, I.D.3    Lobo-Ruppert, S.M.4    McKie-Bell, P.5    Grizzle, W.6    Hayes, M.R.7    Broker, T.R.8    Chow, L.T.9    Ruppert, J.M.10
  • 48
    • 34248141152 scopus 로고    scopus 로고
    • Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract
    • Freberg C.T., Dahl J.A., Timoskainen S. and Collas P. (2007). Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract. Mol. Biol. Cell 18, 1543-1553.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1543-1553
    • Freberg, C.T.1    Dahl, J.A.2    Timoskainen, S.3    Collas, P.4
  • 50
    • 0029969727 scopus 로고    scopus 로고
    • A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells
    • Garrett-Sinha L.A., Eberspaecher H., Seldin M.F. and de Crombrugghe B. (1996). A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. J. Biol. Chem. 271, 31384-31390.
    • (1996) J. Biol. Chem , vol.271 , pp. 31384-31390
    • Garrett-Sinha, L.A.1    Eberspaecher, H.2    Seldin, M.F.3    de Crombrugghe, B.4
  • 51
    • 0034160164 scopus 로고    scopus 로고
    • Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction
    • Geiman D.E., Ton-That H., Johnson J.M. and Yang V.W. (2000). Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction. Nucleic Acids Res. 28, 1106-1113.
    • (2000) Nucleic Acids Res , vol.28 , pp. 1106-1113
    • Geiman, D.E.1    Ton-That, H.2    Johnson, J.M.3    Yang, V.W.4
  • 52
    • 57749110620 scopus 로고    scopus 로고
    • Notch inhibits expression of the kruppel-like factor 4 tumor suppressor in the intestinal epithelium
    • Ghaleb A.M., Aggarwal G., Bialkowska A.B., Nandan M.O. and Yang V.W. (2008). Notch inhibits expression of the kruppel-like factor 4 tumor suppressor in the intestinal epithelium. Mol. Cancer Res. 6, 1920-1927.
    • (2008) Mol. Cancer Res , vol.6 , pp. 1920-1927
    • Ghaleb, A.M.1    Aggarwal, G.2    Bialkowska, A.B.3    Nandan, M.O.4    Yang, V.W.5
  • 53
    • 34147108779 scopus 로고    scopus 로고
    • Krüppel-like factor 4 exhibits antiapoptotic activity following gammaradiation- induced DNA damage
    • Ghaleb A.M., Katz J.P., Kaestner K.H., Du J.X. and Yang V.W. (2007a). Krüppel-like factor 4 exhibits antiapoptotic activity following gammaradiation- induced DNA damage. Oncogene 26, 2365-2373.
    • (2007) Oncogene , vol.26 , pp. 2365-2373
    • Ghaleb, A.M.1    Katz, J.P.2    Kaestner, K.H.3    Du, J.X.4    Yang, V.W.5
  • 54
    • 34547642699 scopus 로고    scopus 로고
    • Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
    • Ghaleb A.M., McConnell B.B., Nandan M.O., Katz J.P., Kaestner K.H. and Yang V.W. (2007b). Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res. 67, 7147-7154.
    • (2007) Cancer Res , vol.67 , pp. 7147-7154
    • Ghaleb, A.M.1    McConnell, B.B.2    Nandan, M.O.3    Katz, J.P.4    Kaestner, K.H.5    Yang, V.W.6
  • 56
    • 48049108950 scopus 로고    scopus 로고
    • Chromosomal gains and losses indicate oncogene and tumor suppressor gene candidates in salivary gland tumors
    • Giefing M., Wierzbicka M., Rydzanicz M., Cegla R., Kujawski M. and Szyfter K. (2008). Chromosomal gains and losses indicate oncogene and tumor suppressor gene candidates in salivary gland tumors. Neoplasma 55, 55-60.
    • (2008) Neoplasma , vol.55 , pp. 55-60
    • Giefing, M.1    Wierzbicka, M.2    Rydzanicz, M.3    Cegla, R.4    Kujawski, M.5    Szyfter, K.6
  • 57
    • 17444423289 scopus 로고    scopus 로고
    • Wnt signaling in the intestinal epithelium: From endoderm to cancer
    • Gregorieff A. and Clevers H. (2005). Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev. 19, 877-890.
    • (2005) Genes Dev , vol.19 , pp. 877-890
    • Gregorieff, A.1    Clevers, H.2
  • 58
    • 84862112420 scopus 로고    scopus 로고
    • Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification
    • In Press
    • Guo P., Dong X.Y., Zhang X., Zhao K.W., Sun X., Li Q. and Dong J.T. (2008). Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. J. Biol. Chem. (In Press).
    • (2008) J. Biol. Chem
    • Guo, P.1    Dong, X.Y.2    Zhang, X.3    Zhao, K.W.4    Sun, X.5    Li, Q.6    Dong, J.T.7
  • 62
    • 0026657846 scopus 로고
    • Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene
    • Imataka H., Sogawa K., Yasumoto K., Kikuchi Y., Sasano K., Kobayashi A., Hayami M. and Fujii-Kuriyama Y. (1992). Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene. EMBO J. 11, 3663-3671.
    • (1992) EMBO J , vol.11 , pp. 3663-3671
    • Imataka, H.1    Sogawa, K.2    Yasumoto, K.3    Kikuchi, Y.4    Sasano, K.5    Kobayashi, A.6    Hayami, M.7    Fujii-Kuriyama, Y.8
  • 63
    • 0032562575 scopus 로고    scopus 로고
    • Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Krüppel-like factor
    • Jenkins T.D., Opitz O.G., Okano J. and Rustgi A.K. (1998). Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Krüppel-like factor. J. Biol. Chem. 273, 10747-10754.
    • (1998) J. Biol. Chem , vol.273 , pp. 10747-10754
    • Jenkins, T.D.1    Opitz, O.G.2    Okano, J.3    Rustgi, A.K.4
  • 65
    • 0037218919 scopus 로고    scopus 로고
    • Sp1- and Krüppel-like transcription factors
    • Kaczynski J., Cook T. and Urrutia R. (2003). Sp1- and Krüppel-like transcription factors. Genome Biol. 4, 206.
    • (2003) Genome Biol , vol.4 , pp. 206
    • Kaczynski, J.1    Cook, T.2    Urrutia, R.3
  • 67
    • 0036340041 scopus 로고    scopus 로고
    • The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
    • Katz J.P., Perreault N., Goldstein B.G., Lee C.S., Labosky P.A., Yang V.W. and Kaestner K.H. (2002). The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129, 2619-2628.
    • (2002) Development , vol.129 , pp. 2619-2628
    • Katz, J.P.1    Perreault, N.2    Goldstein, B.G.3    Lee, C.S.4    Labosky, P.A.5    Yang, V.W.6    Kaestner, K.H.7
  • 68
    • 0032742436 scopus 로고    scopus 로고
    • Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells
    • Kawai-Kowase K., Kurabayashi M., Hoshino Y., Ohyama Y. and Nagai R. (1999). Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells. Circ. Res. 85, 787-795.
    • (1999) Circ. Res , vol.85 , pp. 787-795
    • Kawai-Kowase, K.1    Kurabayashi, M.2    Hoshino, Y.3    Ohyama, Y.4    Nagai, R.5
  • 69
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim J., Chu J., Shen X., Wang J. and Orkin S.H. (2008a). An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061.
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 71
    • 0030960781 scopus 로고    scopus 로고
    • A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene
    • Koritschoner N.P., Bocco J.L., Panzetta-Dutari G.M., Dumur C.I., Flury A. and Patrito L.C. (1997). A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene. J. Biol. Chem. 272, 9573-9580.
    • (1997) J. Biol. Chem , vol.272 , pp. 9573-9580
    • Koritschoner, N.P.1    Bocco, J.L.2    Panzetta-Dutari, G.M.3    Dumur, C.I.4    Flury, A.5    Patrito, L.C.6
  • 73
    • 11244281579 scopus 로고    scopus 로고
    • Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
    • Li Y., McClintick J., Zhong L., Edenberg H.J., Yoder M.C. and Chan R.J. (2005). Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 105, 635-637.
    • (2005) Blood , vol.105 , pp. 635-637
    • Li, Y.1    McClintick, J.2    Zhong, L.3    Edenberg, H.J.4    Yoder, M.C.5    Chan, R.J.6
  • 75
    • 0033485811 scopus 로고    scopus 로고
    • Characterization of the structure and regulation of the murine gene encoding gut-enriched Krüppel-like factor (Krüppel-like factor 4)
    • Mahatan C.S., Kaestner K.H., Geiman D.E. and Yang V.W. (1999). Characterization of the structure and regulation of the murine gene encoding gut-enriched Krüppel-like factor (Krüppel-like factor 4). Nucleic Acids Res. 27, 4562-4569.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4562-4569
    • Mahatan, C.S.1    Kaestner, K.H.2    Geiman, D.E.3    Yang, V.W.4
  • 77
    • 21644462070 scopus 로고    scopus 로고
    • Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells
    • Maruyama M., Ichisaka T., Nakagawa M. and Yamanaka S. (2005). Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J. Biol. Chem. 280, 24371-24379.
    • (2005) J. Biol. Chem , vol.280 , pp. 24371-24379
    • Maruyama, M.1    Ichisaka, T.2    Nakagawa, M.3    Yamanaka, S.4
  • 78
    • 16844374785 scopus 로고    scopus 로고
    • The deacetylase HDAC1 negatively regulates the cardiovascular transcription factor Krüppel-like factor 5 through direct interaction
    • Matsumura T., Suzuki T., Aizawa K., Munemasa Y., Muto S., Horikoshi M. and Nagai R. (2005). The deacetylase HDAC1 negatively regulates the cardiovascular transcription factor Krüppel-like factor 5 through direct interaction. J. Biol. Chem. 280, 12123-12129.
    • (2005) J. Biol. Chem , vol.280 , pp. 12123-12129
    • Matsumura, T.1    Suzuki, T.2    Aizawa, K.3    Munemasa, Y.4    Muto, S.5    Horikoshi, M.6    Nagai, R.7
  • 80
    • 34250216304 scopus 로고    scopus 로고
    • The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology
    • McConnell B.B., Ghaleb A.M., Nandan M.O. and Yang V.W. (2007). The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays 29, 549-557.
    • (2007) Bioessays , vol.29 , pp. 549-557
    • McConnell, B.B.1    Ghaleb, A.M.2    Nandan, M.O.3    Yang, V.W.4
  • 81
    • 41349110850 scopus 로고    scopus 로고
    • Krüppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection
    • McConnell B.B., Klapproth J.M., Sasaki M., Nandan M.O. and Yang V.W. (2008). Krüppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection. Gastroenterology 134, 1007-1016.
    • (2008) Gastroenterology , vol.134 , pp. 1007-1016
    • McConnell, B.B.1    Klapproth, J.M.2    Sasaki, M.3    Nandan, M.O.4    Yang, V.W.5
  • 82
    • 30544449468 scopus 로고    scopus 로고
    • Generation of nuclear transferderived pluripotent ES cells from cloned Cdx2-deficient blastocysts
    • Meissner A. and Jaenisch R. (2006). Generation of nuclear transferderived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature 439, 212-215.
    • (2006) Nature , vol.439 , pp. 212-215
    • Meissner, A.1    Jaenisch, R.2
  • 83
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins
    • Miller I.J. and Bieker J.J. (1993). A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol. Cell. Biol. 13, 2776-2786.
    • (1993) Mol. Cell. Biol , vol.13 , pp. 2776-2786
    • Miller, I.J.1    Bieker, J.J.2
  • 85
    • 0242637390 scopus 로고    scopus 로고
    • Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain
    • Miyamoto S., Suzuki T., Muto S., Aizawa K., Kimura A., Mizuno Y., Nagino T., Imai Y., Adachi N., Horikoshi M. and Nagai R. (2003). Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain. Mol. Cell. Biol. 23, 8528-8541.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 8528-8541
    • Miyamoto, S.1    Suzuki, T.2    Muto, S.3    Aizawa, K.4    Kimura, A.5    Mizuno, Y.6    Nagino, T.7    Imai, Y.8    Adachi, N.9    Horikoshi, M.10    Nagai, R.11
  • 87
    • 24044512379 scopus 로고    scopus 로고
    • Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation
    • Nandan M.O., Chanchevalap S., Dalton W.B. and Yang V.W. (2005). Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation. FEBS Lett. 579, 4757-4762.
    • (2005) FEBS Lett , vol.579 , pp. 4757-4762
    • Nandan, M.O.1    Chanchevalap, S.2    Dalton, W.B.3    Yang, V.W.4
  • 89
    • 2442686555 scopus 로고    scopus 로고
    • Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras
    • Nandan M.O., Yoon H.S., Zhao W., Ouko L.A., Chanchevalap S. and Yang V.W. (2004). Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. Oncogene 23, 3404-3413.
    • (2004) Oncogene , vol.23 , pp. 3404-3413
    • Nandan, M.O.1    Yoon, H.S.2    Zhao, W.3    Ouko, L.A.4    Chanchevalap, S.5    Yang, V.W.6
  • 91
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H., Burdon T., Chambers I. and Smith A. (1998). Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 12, 2048-2060.
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 92
    • 0034031381 scopus 로고    scopus 로고
    • Developmental expression of the mouse gene coding for the Krüppel-like transcription factor KLF5
    • Ohnishi S., Laub F., Matsumoto N., Asaka M., Ramirez F., Yoshida T. and Terada M. (2000). Developmental expression of the mouse gene coding for the Krüppel-like transcription factor KLF5. Dev. Dyn. 217, 421-429.
    • (2000) Dev. Dyn , vol.217 , pp. 421-429
    • Ohnishi, S.1    Laub, F.2    Matsumoto, N.3    Asaka, M.4    Ramirez, F.5    Yoshida, T.6    Terada, M.7
  • 93
    • 44949181877 scopus 로고    scopus 로고
    • SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta
    • Oishi Y., Manabe I., Tobe K., Ohsugi M., Kubota T., Fujiu K., Maemura K., Kubota N., Kadowaki T. and Nagai R. (2008). SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta. Nat. Med. 14, 656-666.
    • (2008) Nat. Med , vol.14 , pp. 656-666
    • Oishi, Y.1    Manabe, I.2    Tobe, K.3    Ohsugi, M.4    Kubota, T.5    Fujiu, K.6    Maemura, K.7    Kubota, N.8    Kadowaki, T.9    Nagai, R.10
  • 95
    • 0025060177 scopus 로고
    • A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
    • Okamoto K., Okazawa H., Okuda A., Sakai M., Muramatsu M. and Hamada H. (1990). A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60, 461-472.
    • (1990) Cell , vol.60 , pp. 461-472
    • Okamoto, K.1    Okazawa, H.2    Okuda, A.3    Sakai, M.4    Muramatsu, M.5    Hamada, H.6
  • 96
    • 0034603864 scopus 로고    scopus 로고
    • The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact
    • Okano J., Opitz O.G., Nakagawa H., Jenkins T.D., Friedman S.L. and Rustgi A.K. (2000). The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact. FEBS Lett. 473, 95-100.
    • (2000) FEBS Lett , vol.473 , pp. 95-100
    • Okano, J.1    Opitz, O.G.2    Nakagawa, H.3    Jenkins, T.D.4    Friedman, S.L.5    Rustgi, A.K.6
  • 97
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germlinecompetent induced pluripotent stem cells
    • Okita K., Ichisaka T. and Yamanaka S. (2007). Generation of germlinecompetent induced pluripotent stem cells. Nature 448, 313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 98
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K., Nakagawa M., Hyenjong H., Ichisaka T. and Yamanaka S. (2008). Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949-953.
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 105
    • 0033178330 scopus 로고    scopus 로고
    • A tale of three fingers: The family of mammalian Sp/XKLF transcription factors
    • Philipsen S. and Suske G. (1999). A tale of three fingers: the family of mammalian Sp/XKLF transcription factors. Nucleic Acids Res. 27, 2991-3000.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2991-3000
    • Philipsen, S.1    Suske, G.2
  • 107
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
    • Reubinoff B.E., Pera M.F., Fong C.Y., Trounson A. and Bongso A. (2000). Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18, 399-404.
    • (2000) Nat. Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 108
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T. and Clevers H. (2005). Wnt signalling in stem cells and cancer. Nature 434, 843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 109
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
    • Rowland B.D., Bernards R. and Peeper D.S. (2005). The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell Biol. 7, 1074-1082.
    • (2005) Nat. Cell Biol , vol.7 , pp. 1074-1082
    • Rowland, B.D.1    Bernards, R.2    Peeper, D.S.3
  • 110
    • 30144442965 scopus 로고    scopus 로고
    • KLF4, p21 and contextdependent opposing forces in cancer
    • Rowland B.D. and Peeper D.S. (2006). KLF4, p21 and contextdependent opposing forces in cancer. Nat. Rev. Cancer 6, 11-23.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 11-23
    • Rowland, B.D.1    Peeper, D.S.2
  • 111
    • 0025291459 scopus 로고
    • Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
    • Scholer H.R., Dressler G.R., Balling R., Rohdewohld H. and Gruss P. (1990). Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J. 9, 2185-2195.
    • (1990) EMBO J , vol.9 , pp. 2185-2195
    • Scholer, H.R.1    Dressler, G.R.2    Balling, R.3    Rohdewohld, H.4    Gruss, P.5
  • 112
    • 0023057732 scopus 로고
    • A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene
    • Schuh R., Aicher W., Gaul U., Cote S., Preiss A., Maier D., Seifert E., Nauber U., Schroder C. and Kemler R. (1986). A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene. Cell 47, 1025-1032.
    • (1986) Cell , vol.47 , pp. 1025-1032
    • Schuh, R.1    Aicher, W.2    Gaul, U.3    Cote, S.4    Preiss, A.5    Maier, D.6    Seifert, E.7    Nauber, U.8    Schroder, C.9    Kemler, R.10
  • 113
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Segre J.A., Bauer C. and Fuchs E. (1999). Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 22, 356-360.
    • (1999) Nat. Genet , vol.22 , pp. 356-360
    • Segre, J.A.1    Bauer, C.2    Fuchs, E.3
  • 114
    • 0033572710 scopus 로고    scopus 로고
    • Isolation and characterization of a gene encoding human Krüppel-like factor 5 (IKLF): Binding to the CAAT/GT box of the mouse lactoferrin gene promoter
    • Shi H., Zhang Z., Wang X., Liu S. and Teng C.T. (1999). Isolation and characterization of a gene encoding human Krüppel-like factor 5 (IKLF): binding to the CAAT/GT box of the mouse lactoferrin gene promoter. Nucleic Acids Res. 27, 4807-4815.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4807-4815
    • Shi, H.1    Zhang, Z.2    Wang, X.3    Liu, S.4    Teng, C.T.5
  • 115
    • 0037351345 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian nuclear transfer
    • Shi W., Zakhartchenko V. and Wolf E. (2003). Epigenetic reprogramming in mammalian nuclear transfer. Differentiation 71, 91-113.
    • (2003) Differentiation , vol.71 , pp. 91-113
    • Shi, W.1    Zakhartchenko, V.2    Wolf, E.3
  • 116
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
    • Shi Y., Desponts C., Do J.T., Hahm H.S., Scholer H.R. and Ding S. (2008). Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3, 568-574.
    • (2008) Cell Stem Cell , vol.3 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3    Hahm, H.S.4    Scholer, H.R.5    Ding, S.6
  • 117
    • 0034238112 scopus 로고    scopus 로고
    • Gutenriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif
    • Shie J.L., Chen Z.Y., Fu M., Pestell R.G. and Tseng C.C. (2000). Gutenriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif. Nucleic Acids Res. 28, 2969-2976.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2969-2976
    • Shie, J.L.1    Chen, Z.Y.2    Fu, M.3    Pestell, R.G.4    Tseng, C.C.5
  • 118
    • 0030746063 scopus 로고    scopus 로고
    • Two potent nuclear localization signals in the gut-enriched Krüppel-like factor define a subfamily of closely related Krüppel proteins
    • Shields J.M. and Yang V.W. (1997). Two potent nuclear localization signals in the gut-enriched Krüppel-like factor define a subfamily of closely related Krüppel proteins. J. Biol. Chem. 272, 18504-18507.
    • (1997) J. Biol. Chem , vol.272 , pp. 18504-18507
    • Shields, J.M.1    Yang, V.W.2
  • 119
    • 0032004389 scopus 로고    scopus 로고
    • Identification of the DNA sequence that interacts with the gut-enriched Krüppel-like factor
    • Shields J.M. and Yang V.W. (1998). Identification of the DNA sequence that interacts with the gut-enriched Krüppel-like factor. Nucleic Acids Res. 26, 796-802.
    • (1998) Nucleic Acids Res , vol.26 , pp. 796-802
    • Shields, J.M.1    Yang, V.W.2
  • 120
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest
    • Shields J.M., Christy R.J. and Yang V.W. (1996). Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J. Biol. Chem. 271, 20009-20017.
    • (1996) J. Biol. Chem , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 122
    • 0024245022 scopus 로고
    • Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
    • Smith A.G., Heath J.K., Donaldson D.D., Wong G.G., Moreau J., Stahl M. and Rogers D. (1988). Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336, 688-690.
    • (1988) Nature , vol.336 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3    Wong, G.G.4    Moreau, J.5    Stahl, M.6    Rogers, D.7
  • 123
  • 124
    • 45449094570 scopus 로고    scopus 로고
    • Reprogramming of pancreatic beta cells into induced pluripotent stem cells
    • Stadtfeld M., Brennand K. and Hochedlinger K. (2008a). Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Curr. Biol. 18, 890-894.
    • (2008) Curr. Biol , vol.18 , pp. 890-894
    • Stadtfeld, M.1    Brennand, K.2    Hochedlinger, K.3
  • 125
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M., Nagaya M., Utikal J., Weir G. and Hochedlinger K. (2008b). Induced pluripotent stem cells generated without viral integration. Science 322, 945-949.
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 127
    • 0035831436 scopus 로고    scopus 로고
    • Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation
    • Sun R., Chen X. and Yang V.W. (2001). Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation. J. Biol. Chem. 276, 6897-6900.
    • (2001) J. Biol. Chem , vol.276 , pp. 6897-6900
    • Sun, R.1    Chen, X.2    Yang, V.W.3
  • 128
    • 0035985280 scopus 로고    scopus 로고
    • Human Krüppel-like factor5/KLF5: Synergy with NF-kappaB/Rel factors and expression in human skin and hair follicles
    • Sur I., Unden A.B. and Toftgard R. (2002). Human Krüppel-like factor5/KLF5: synergy with NF-kappaB/Rel factors and expression in human skin and hair follicles. Eur. J. Cell Biol. 81, 323-334.
    • (2002) Eur. J. Cell Biol , vol.81 , pp. 323-334
    • Sur, I.1    Unden, A.B.2    Toftgard, R.3
  • 129
    • 33845790551 scopus 로고    scopus 로고
    • Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells
    • Swamynathan S.K., Katz J.P., Kaestner K.H., Ashery-Padan R., Crawford M.A. and Piatigorsky J. (2007). Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol. Cell. Biol. 27, 182-194.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 182-194
    • Swamynathan, S.K.1    Katz, J.P.2    Kaestner, K.H.3    Ashery-Padan, R.4    Crawford, M.A.5    Piatigorsky, J.6
  • 130
    • 1842364873 scopus 로고    scopus 로고
    • Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells
    • Tada M., Tada T., Lefebvre L., Barton S.C. and Surani M.A. (1997). Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J. 16, 6510-6520.
    • (1997) EMBO J , vol.16 , pp. 6510-6520
    • Tada, M.1    Tada, T.2    Lefebvre, L.3    Barton, S.C.4    Surani, M.A.5
  • 131
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K. and Yamanaka S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 132
    • 28644443829 scopus 로고    scopus 로고
    • Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells
    • Taranger C.K., Noer A., Sorensen A.L., Hakelien A.M., Boquest A.C. and Collas P. (2005). Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol. Biol. Cell 16, 5719-5735.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5719-5735
    • Taranger, C.K.1    Noer, A.2    Sorensen, A.L.3    Hakelien, A.M.4    Boquest, A.C.5    Collas, P.6
  • 133
    • 0037383685 scopus 로고    scopus 로고
    • Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development
    • Tokuzawa Y., Kaiho E., Maruyama M., Takahashi K., Mitsui K., Maeda M., Niwa H. and Yamanaka S. (2003). Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol. Cell. Biol. 23, 2699-2708.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 2699-2708
    • Tokuzawa, Y.1    Kaiho, E.2    Maruyama, M.3    Takahashi, K.4    Mitsui, K.5    Maeda, M.6    Niwa, H.7    Yamanaka, S.8
  • 134
    • 0031451645 scopus 로고    scopus 로고
    • Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis
    • Ton-That H., Kaestner K.H., Shields J.M., Mahatanankoon C.S. and Yang V.W. (1997). Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis. FEBS Lett. 419, 239-243.
    • (1997) FEBS Lett , vol.419 , pp. 239-243
    • Ton-That, H.1    Kaestner, K.H.2    Shields, J.M.3    Mahatanankoon, C.S.4    Yang, V.W.5
  • 135
    • 33646423520 scopus 로고    scopus 로고
    • Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer
    • Tong D., Czerwenka K., Heinze G., Ryffel M., Schuster E., Witt A., Leodolter S. and Zeillinger R. (2006). Expression of KLF5 is a prognostic factor for disease-free survival and overall survival in patients with breast cancer. Clin. Cancer Res. 12, 2442-2448.
    • (2006) Clin. Cancer Res , vol.12 , pp. 2442-2448
    • Tong, D.1    Czerwenka, K.2    Heinze, G.3    Ryffel, M.4    Schuster, E.5    Witt, A.6    Leodolter, S.7    Zeillinger, R.8
  • 136
    • 0033137330 scopus 로고    scopus 로고
    • Mammalian Krüppel-like transcription factors: More than just a pretty finger
    • Turner J. and Crossley M. (1999). Mammalian Krüppel-like transcription factors: more than just a pretty finger. Trends Biochem. Sci. 24, 236-240.
    • (1999) Trends Biochem. Sci , vol.24 , pp. 236-240
    • Turner, J.1    Crossley, M.2
  • 137
    • 0032560827 scopus 로고    scopus 로고
    • Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
    • Wakayama T., Perry A.C., Zuccotti M., Johnson K.R. and Yanagimachi R. (1998). Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394, 369-374.
    • (1998) Nature , vol.394 , pp. 369-374
    • Wakayama, T.1    Perry, A.C.2    Zuccotti, M.3    Johnson, K.R.4    Yanagimachi, R.5
  • 140
    • 37549008674 scopus 로고    scopus 로고
    • c-Myc is dispensable for direct reprogramming of mouse fibroblasts
    • Wernig M., Meissner A., Cassady J.P. and Jaenisch R. (2008b). c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2, 10-12.
    • (2008) Cell Stem Cell , vol.2 , pp. 10-12
    • Wernig, M.1    Meissner, A.2    Cassady, J.P.3    Jaenisch, R.4
  • 143
    • 33749339326 scopus 로고    scopus 로고
    • Transcriptional profiling of the cell cycle checkpoint gene kruppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis
    • Whitney E.M., Ghaleb A.M., Chen X. and Yang V.W. (2006). Transcriptional profiling of the cell cycle checkpoint gene kruppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis. Gene Expr. 13, 85-96.
    • (2006) Gene Expr , vol.13 , pp. 85-96
    • Whitney, E.M.1    Ghaleb, A.M.2    Chen, X.3    Yang, V.W.4
  • 145
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • Wilmut I., Schnieke A.E., McWhir J., Kind A.J. and Campbell K.H. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813.
    • (1997) Nature , vol.385 , pp. 810-813
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.5
  • 146
    • 44749090831 scopus 로고    scopus 로고
    • Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence
    • Xu J., Lu B., Xu F., Gu H., Fang Y., Huang Q. and Lai M. (2008). Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence. J. Cancer Res. Clin. Oncol. 134, 891-898.
    • (2008) J. Cancer Res. Clin. Oncol , vol.134 , pp. 891-898
    • Xu, J.1    Lu, B.2    Xu, F.3    Gu, H.4    Fang, Y.5    Huang, Q.6    Lai, M.7
  • 147
    • 34249863603 scopus 로고    scopus 로고
    • Strategies and new developments in the generation of patient-specific pluripotent stem cells
    • Yamanaka S. (2007). Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1, 39-49.
    • (2007) Cell Stem Cell , vol.1 , pp. 39-49
    • Yamanaka, S.1
  • 149
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying Q.L., Nichols J., Chambers I. and Smith A. (2003). BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115, 281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 150
    • 1042301369 scopus 로고    scopus 로고
    • Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage
    • Yoon H.S. and Yang V.W. (2004). Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage. J. Biol. Chem. 279, 5035-5041.
    • (2004) J. Biol. Chem , vol.279 , pp. 5035-5041
    • Yoon, H.S.1    Yang, V.W.2
  • 151
    • 0037462796 scopus 로고    scopus 로고
    • Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
    • Yoon H.S., Chen X. and Yang V.W. (2003). Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J. Biol. Chem. 278, 2101-2105.
    • (2003) J. Biol. Chem , vol.278 , pp. 2101-2105
    • Yoon, H.S.1    Chen, X.2    Yang, V.W.3
  • 152
    • 21244499737 scopus 로고    scopus 로고
    • Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage
    • Yoon H.S., Ghaleb A.M., Nandan M.O., Hisamuddin I.M., Dalton W.B. and Yang V.W. (2005). Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. Oncogene 24, 4017-4025.
    • (2005) Oncogene , vol.24 , pp. 4017-4025
    • Yoon, H.S.1    Ghaleb, A.M.2    Nandan, M.O.3    Hisamuddin, I.M.4    Dalton, W.B.5    Yang, V.W.6
  • 154
    • 57349096430 scopus 로고    scopus 로고
    • Krüppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids
    • Yoshida T., Gan Q. and Owens G.K. (2008a). Krüppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids. Am. J. Physiol. Cell. Physiol. 295, C1175-1182.
    • (2008) Am. J. Physiol. Cell. Physiol , vol.295
    • Yoshida, T.1    Gan, Q.2    Owens, G.K.3
  • 155
    • 48249113711 scopus 로고    scopus 로고
    • Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury
    • Yoshida T., Kaestner K.H. and Owens G.K. (2008b). Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ. Res. 102, 1548-1557.
    • (2008) Circ. Res , vol.102 , pp. 1548-1557
    • Yoshida, T.1    Kaestner, K.H.2    Owens, G.K.3
  • 158
    • 0032503693 scopus 로고    scopus 로고
    • The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion
    • Zhang W., Shields J.M., Sogawa K., Fujii-Kuriyama Y. and Yang V.W. (1998). The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. J. Biol. Chem. 273, 17917-17925.
    • (1998) J. Biol. Chem , vol.273 , pp. 17917-17925
    • Zhang, W.1    Shields, J.M.2    Sogawa, K.3    Fujii-Kuriyama, Y.4    Yang, V.W.5
  • 159
    • 0034674712 scopus 로고    scopus 로고
    • The gut-enriched Krüppel-like factor (Krüppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
    • Zhang W., Geiman D.E., Shields J.M., Dang D.T., Mahatan C.S., Kaestner K.H., Biggs J.R., Kraft A.S. and Yang V.W. (2000). The gut-enriched Krüppel-like factor (Krüppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J. Biol. Chem. 275, 18391-18398.
    • (2000) J. Biol. Chem , vol.275 , pp. 18391-18398
    • Zhang, W.1    Geiman, D.E.2    Shields, J.M.3    Dang, D.T.4    Mahatan, C.S.5    Kaestner, K.H.6    Biggs, J.R.7    Kraft, A.S.8    Yang, V.W.9
  • 161
    • 0038137207 scopus 로고    scopus 로고
    • Phosphorylation of Krüppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation function
    • Zhang Z. and Teng C.T. (2003). Phosphorylation of Krüppel-like factor 5 (KLF5/IKLF) at the CBP interaction region enhances its transactivation function. Nucleic Acids Res. 31, 2196-2208.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2196-2208
    • Zhang, Z.1    Teng, C.T.2
  • 162
    • 0842329848 scopus 로고    scopus 로고
    • Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • Zhao W., Hisamuddin I.M., Nandan M.O., Babbin B.A., Lamb N.E. and Yang V.W. (2004). Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 23, 395-402.
    • (2004) Oncogene , vol.23 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3    Babbin, B.A.4    Lamb, N.E.5    Yang, V.W.6
  • 163
    • 0035164288 scopus 로고    scopus 로고
    • Identification of a mouse homolog of the human BTEB2 transcription factor as a betacatenin- independent Wnt-1-responsive gene
    • Ziemer L.T., Pennica D. and Levine A.J. (2001). Identification of a mouse homolog of the human BTEB2 transcription factor as a betacatenin- independent Wnt-1-responsive gene. Mol. Cell. Biol 21, 562-574.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 562-574
    • Ziemer, L.T.1    Pennica, D.2    Levine, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.