-
1
-
-
1642540218
-
Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage
-
Brodsky MH, Weinert BT, Tsang G, Rong YS, McGinnis NM, Golic KG et al. (2004). Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol Cell Biol 24: 1219-1231.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1219-1231
-
-
Brodsky, M.H.1
Weinert, B.T.2
Tsang, G.3
Rong, Y.S.4
McGinnis, N.M.5
Golic, K.G.6
-
2
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L et al. (1999). Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 104: 263-269.
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
-
3
-
-
0034234211
-
Cooperative effects of genes controlling the G(2)/M checkpoint
-
Chan TA, Hwang PM, Hermeking H, Kinzler KW, Vogelstein B. (2000). Cooperative effects of genes controlling the G(2)/M checkpoint. Genes Dev 14: 1584-1588.
-
(2000)
Genes Dev
, vol.14
, pp. 1584-1588
-
-
Chan, T.A.1
Hwang, P.M.2
Hermeking, H.3
Kinzler, K.W.4
Vogelstein, B.5
-
4
-
-
0035839554
-
Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
-
Chen X, Johns DC, Geiman DE, Marban E, Dang DT, Hamlin G et al. (2001). Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J Biol Chem 276: 30423-30428.
-
(2001)
J Biol Chem
, vol.276
, pp. 30423-30428
-
-
Chen, X.1
Johns, D.C.2
Geiman, D.E.3
Marban, E.4
Dang, D.T.5
Hamlin, G.6
-
5
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML et al. (1993). Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
-
6
-
-
0035833319
-
Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2
-
Dang DT, Mahatan CS, Dang LH, Agboola IA, Yang VW. (2001). Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2. Oncogene 20: 4884-4890.
-
(2001)
Oncogene
, vol.20
, pp. 4884-4890
-
-
Dang, D.T.1
Mahatan, C.S.2
Dang, L.H.3
Agboola, I.A.4
Yang, V.W.5
-
7
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM et al. (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
8
-
-
3242690522
-
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
-
Erster S, Mihara M, Kim RH, Petrenko O, Moll UM. (2004). In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 24: 6728-6741.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6728-6741
-
-
Erster, S.1
Mihara, M.2
Kim, R.H.3
Petrenko, O.4
Moll, U.M.5
-
9
-
-
0141757504
-
P53 and radiation responses
-
Fei P, El-Deiry WS. (2003). P53 and radiation responses. Oncogene 22: 5774-5783.
-
(2003)
Oncogene
, vol.22
, pp. 5774-5783
-
-
Fei, P.1
El-Deiry, W.S.2
-
10
-
-
20144382755
-
Induction of KLF4 in basal keratinocytes blocks the proliferation- differentiation switch and initiates squamous epithelial dysplasia
-
Foster KW, Liu Z, Nail CD, Li X, Fitzgerald TJ, Bailey SK et al. (2005). Induction of KLF4 in basal keratinocytes blocks the proliferation- differentiation switch and initiates squamous epithelial dysplasia. Oncogene 24: 1491-1500.
-
(2005)
Oncogene
, vol.24
, pp. 1491-1500
-
-
Foster, K.W.1
Liu, Z.2
Nail, C.D.3
Li, X.4
Fitzgerald, T.J.5
Bailey, S.K.6
-
11
-
-
0033057439
-
Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF
-
Foster KW, Ren S, Louro ID, Lobo-Ruppert SM, McKie-Bell P, Grizzle W et al. (1999). Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF. Cell Growth Differ 10: 423-434.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 423-434
-
-
Foster, K.W.1
Ren, S.2
Louro, I.D.3
Lobo-Ruppert, S.M.4
McKie-Bell, P.5
Grizzle, W.6
-
12
-
-
0029969727
-
A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells
-
Garrett-Sinha LA, Eberspaecher H, Seldin MF, de Crombrugghe B. (1996). A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. J Biol Chem 271: 31384-31390.
-
(1996)
J Biol Chem
, vol.271
, pp. 31384-31390
-
-
Garrett-Sinha, L.A.1
Eberspaecher, H.2
Seldin, M.F.3
de Crombrugghe, B.4
-
13
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S et al. (1997). 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell 1: 3-11.
-
(1997)
Mol Cell
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
Thiagalingam, S.6
-
14
-
-
12944269061
-
Identification and characterization of a p53 homologue in Drosophila melanogaster
-
Jin S, Martinek S, Joo WS, Wortman JR, Mirkovic N, Sali A et al. (2000). Identification and characterization of a p53 homologue in Drosophila melanogaster. Proc Natl Acad Sci USA 97: 7301-7306.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7301-7306
-
-
Jin, S.1
Martinek, S.2
Joo, W.S.3
Wortman, J.R.4
Mirkovic, N.5
Sali, A.6
-
15
-
-
17144401799
-
Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach
-
Katz JP, Perreault N, Goldstein BG, Actman L, McNally SR, Silberg DG et al. (2005). Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology 128: 935-945.
-
(2005)
Gastroenterology
, vol.128
, pp. 935-945
-
-
Katz, J.P.1
Perreault, N.2
Goldstein, B.G.3
Actman, L.4
McNally, S.R.5
Silberg, D.G.6
-
16
-
-
0036340041
-
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
-
Katz JP, Perreault N, Goldstein BG, Lee CS, Labosky PA, Yang VW et al. (2002). The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129: 2619-2628.
-
(2002)
Development
, vol.129
, pp. 2619-2628
-
-
Katz, J.P.1
Perreault, N.2
Goldstein, B.G.3
Lee, C.S.4
Labosky, P.A.5
Yang, V.W.6
-
17
-
-
0035382714
-
Radiotherapy and cellular signalling
-
Lewanski CR, Gullick WJ. (2001). Radiotherapy and cellular signalling. Lancet Oncol 2: 366-370.
-
(2001)
Lancet Oncol
, vol.2
, pp. 366-370
-
-
Lewanski, C.R.1
Gullick, W.J.2
-
18
-
-
0346455759
-
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
-
Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK et al. (2004). Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet 36: 63-68.
-
(2004)
Nat Genet
, vol.36
, pp. 63-68
-
-
Liu, G.1
Parant, J.M.2
Lang, G.3
Chau, P.4
Chavez-Reyes, A.5
El-Naggar, A.K.6
-
19
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. (1993a). p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
20
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. (1993b). p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
21
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P et al. (2003). p53 has a direct apoptogenic role at the mitochondria. Mol Cell 11: 577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
-
22
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
23
-
-
30144440248
-
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
-
Rowland BD, Bernards R, Peeper DS. (2005). The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat Cell Biol 7: 1074-1082.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 1074-1082
-
-
Rowland, B.D.1
Bernards, R.2
Peeper, D.S.3
-
24
-
-
30144442965
-
KLF4, p21 and context-dependent opposing forces in cancer
-
Rowland BD, Peeper DS. (2006). KLF4, p21 and context-dependent opposing forces in cancer. Nat Rev Cancer 6: 11-23.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 11-23
-
-
Rowland, B.D.1
Peeper, D.S.2
-
25
-
-
0036527761
-
Dissecting p53 tumor suppressor functions in vivo
-
Schmitt CA, Fridman JS, Yang M, Baranov E, Hoffman RM, Lowe SW. (2002). Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 1: 289-298.
-
(2002)
Cancer Cell
, vol.1
, pp. 289-298
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Baranov, E.4
Hoffman, R.M.5
Lowe, S.W.6
-
26
-
-
0035975986
-
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
-
Schumacher B, Hofmann K, Boulton S, Gartner A. (2001). The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Curr Biol 11: 1722-1727.
-
(2001)
Curr Biol
, vol.11
, pp. 1722-1727
-
-
Schumacher, B.1
Hofmann, K.2
Boulton, S.3
Gartner, A.4
-
27
-
-
0029829236
-
Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest
-
Shields JM, Christy RJ, Yang VW. (1996). Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest. J Biol Chem 271: 20009-20017.
-
(1996)
J Biol Chem
, vol.271
, pp. 20009-20017
-
-
Shields, J.M.1
Christy, R.J.2
Yang, V.W.3
-
28
-
-
0030746063
-
Two potent nuclear localization signals in the gut-enriched Kruppel-like factor define a subfamily of closely related Kruppel proteins
-
Shields JM, Yang VW. (1997). Two potent nuclear localization signals in the gut-enriched Kruppel-like factor define a subfamily of closely related Kruppel proteins. J Biol Chem 272: 18504-18507.
-
(1997)
J Biol Chem
, vol.272
, pp. 18504-18507
-
-
Shields, J.M.1
Yang, V.W.2
-
29
-
-
0028169994
-
p53-dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T et al. (1994). p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711.
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
Jacks, T.6
-
31
-
-
0028849274
-
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T, Kinzler KW, Vogelstein B. (1995). p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 55: 5187-5190.
-
(1995)
Cancer Res
, vol.55
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
32
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman T, Lengauer C, Kinzler KW, Vogelstein B. (1996). Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381: 713-716.
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
33
-
-
0030842655
-
Cell-cycle arrest versus cell death in cancer therapy
-
Waldman T, Zhang Y, Dillehay L, Yu J, Kinzler K, Vogelstein B et al. (1997). Cell-cycle arrest versus cell death in cancer therapy. Nat Med 3: 1034-1036.
-
(1997)
Nat Med
, vol.3
, pp. 1034-1036
-
-
Waldman, T.1
Zhang, Y.2
Dillehay, L.3
Yu, J.4
Kinzler, K.5
Vogelstein, B.6
-
34
-
-
16844386207
-
Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression
-
Wei D, Gong W, Kanai M, Schlunk C, Wang L, Yao JC et al. (2005). Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res 65: 2746-2754.
-
(2005)
Cancer Res
, vol.65
, pp. 2746-2754
-
-
Wei, D.1
Gong, W.2
Kanai, M.3
Schlunk, C.4
Wang, L.5
Yao, J.C.6
-
35
-
-
0037462796
-
Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
-
Yoon HS, Chen X, Yang VW. (2003). Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J Biol Chem 278: 2101-2105.
-
(2003)
J Biol Chem
, vol.278
, pp. 2101-2105
-
-
Yoon, H.S.1
Chen, X.2
Yang, V.W.3
-
36
-
-
21244499737
-
Kruppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage
-
Yoon HS, Ghaleb AM, Nandan MO, Hisamuddin IM, Dalton WB, Yang VW. (2005). Kruppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. Oncogene 24: 4017-4025.
-
(2005)
Oncogene
, vol.24
, pp. 4017-4025
-
-
Yoon, H.S.1
Ghaleb, A.M.2
Nandan, M.O.3
Hisamuddin, I.M.4
Dalton, W.B.5
Yang, V.W.6
-
37
-
-
1042301369
-
Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage
-
Yoon HS, Yang VW. (2004). Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage. J Biol Chem 279: 5035-5041.
-
(2004)
J Biol Chem
, vol.279
, pp. 5035-5041
-
-
Yoon, H.S.1
Yang, V.W.2
-
38
-
-
4043095823
-
Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells
-
Yu J, Tiwari S, Steiner P, Zhang L. (2003). Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells. Cancer Biol Ther 2: 694-699.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 694-699
-
-
Yu, J.1
Tiwari, S.2
Steiner, P.3
Zhang, L.4
-
39
-
-
18144416611
-
The transcriptional targets of p53 in apoptosis control
-
Yu J, Zhang L. (2005). The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 331: 851-858.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 851-858
-
-
Yu, J.1
Zhang, L.2
-
40
-
-
0034674712
-
The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
-
Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, Kaestner KH et al. (2000). The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J Biol Chem 275: 18391-18398.
-
(2000)
J Biol Chem
, vol.275
, pp. 18391-18398
-
-
Zhang, W.1
Geiman, D.E.2
Shields, J.M.3
Dang, D.T.4
Mahatan, C.S.5
Kaestner, K.H.6
-
41
-
-
0032503693
-
The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion
-
Zhang W, Shields JM, Sogawa K, Fujii-Kuriyama Y, Yang VW. (1998). The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. J Biol Chem 273: 17917-17925.
-
(1998)
J Biol Chem
, vol.273
, pp. 17917-17925
-
-
Zhang, W.1
Shields, J.M.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
Yang, V.W.5
-
42
-
-
0842329848
-
Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
-
Zhao W, Hisamuddin IM, Nandan MO, Babbin BA, Lamb NE, Yang VW. (2004). Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 23: 395-402.
-
(2004)
Oncogene
, vol.23
, pp. 395-402
-
-
Zhao, W.1
Hisamuddin, I.M.2
Nandan, M.O.3
Babbin, B.A.4
Lamb, N.E.5
Yang, V.W.6
|