SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ

Nature Medicine

Volumn 14, Issue 6, 2008, Pages 656-666

  Oishi, Yumiko ^a,b   Manabe, Ichiro ^a   Tobe, Kazuyuki ^a,c   Ohsugi, Mitsuru ^a   Kubota, Tetsuya ^a,b   Fujiu, Katsuhito ^a   Maemura, Koji ^a   Kubota, Naoto ^a,b   Kadowaki, Takashi ^a,b   Nagai, Ryozo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE PALMITOYL TRANSFERASE 1B; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GENE PRODUCT; KRUPPEL LIKE FACTOR; KRUPPEL LIKE TRANSCRIPTION FACTOR 5; LIPID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SUMO PROTEIN; UBIQUITIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR DISEASE; COMPLEX FORMATION; CONTROLLED STUDY; CPT1B GENE; ENERGY EXPENDITURE; ENERGY METABOLISM; FOOD INTAKE; GENE; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; HYPERCHOLESTEROLEMIA; KLF5 GENE; LIPID METABOLISM; LIPID OXIDATION; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SOLEUS MUSCLE; SUMOYLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UCP2 GENE; UCP3 GENE; UPREGULATION; WILD TYPE;

ANIMALS; BODY TEMPERATURE; CELL LINE; CERCOPITHECUS AETHIOPS; CHOLESTEROL; COS CELLS; CROSSES, GENETIC; GENES, REPORTER; GLUCOSE TOLERANCE TEST; HETEROZYGOTE; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEPTIN; LIPID METABOLISM; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; MYOBLASTS; OXYGEN CONSUMPTION; PPAR DELTA; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; TRANSCRIPTION, GENETIC;

MUS;

EID: 44949181877     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1756     Document Type: Article

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