Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1783, Issue 6, 2008, Pages 1229-1236

  Cullingford, Timothy E ^a   Butler, Matthew J ^a   Marshall, Andrew K ^a   Tham, El Li ^a   Sugden, Peter H ^a   Clerk, Angela ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Cardiac myocytes; Cytokines; Endothelin 1; Gene expression; Immediate early genes; Kr ppel like factors

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLOHEXIMIDE; CYTOKINE; ENDOTHELIN 1; INTERLEUKIN 1BETA; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 11; KRUPPEL LIKE FACTOR 15; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 3; KRUPPEL LIKE FACTOR 4; KRUPPEL LIKE FACTOR 5; KRUPPEL LIKE FACTOR 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HYPERTROPHY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; STIMULUS;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELLS, CULTURED; ENDOTHELIN-1; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; INTERLEUKIN-1BETA; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MYOCYTES, CARDIAC; OXIDANTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 43549107895     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2008.03.007     Document Type: Article

References (56)

1. Kaczynski J., Cook T., and Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biol. 4 (2003) 206
2. Suske G., Bruford E., and Philipsen S. Mammalian SP/KLF transcription factors: bring in the family. Genomics 85 (2005) 551-556
3. van Vliet J., Crofts L.A., Quinlan K.G.R., Czolij R., Perkins A.C., and Crossley M. Human KLF17 is a new member of the Sp/KLF family of transcription factors. Genomics 87 (2006) 474-482
4. Lomberk G., and Urrutia R. The family feud: turning off Sp1 by Sp1-like Klf proteins. Biochem. J. 392 (2005) 1-11
5. Dang D.T., Zhao W., Mahatan C.S., Geiman D.E., and Yang V.W. Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene. Nucleic Acids Res. 30 (2002) 2736-2741
6. Bieker J.J. Krüppel-like factors: three fingers in many pies. J. Biol. Chem. 276 (2001) 34355-34358
7. Suzuki T., Aizawa K., Matsumura T., and Nagai R. Vascular implications of the Krüppel-like family of transcription factors. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 1135-1141
8. Ghaleb A.M., Nandan M.O., Chanchevalap S., Dalton W.B., Hisamuddin I.M., and Yang V.W. Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation. Cell Res. 15 (2005) 92-96
9. Yang Y., Goldstein B.G., Chao H.H., and Katz J.P. KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol. Ther. 4 (2005) 1216-1221
10. Dorn G.W., Robbins J., and Sugden P.H. Phenotyping hypertrophy; eschew obfuscation. Circ. Res. 92 (2003) 1171-1175
11. Sugden P.H. An overview of endothelin signaling in the cardiac myocyte. J. Mol. Cell. Cardiol. 35 (2003) 871-886
12. Clerk A., Cole S.M., Cullingford T.E., Harrison J.G., Jormakka M., and Valks D.M. Regulation of cardiac myocyte cell death. Pharmacol. Ther. 97 (2003) 223-261
13. Clerk A., Cullingford T.E., Fuller S.J., Giraldo A., Markou T., Pikkarainen S., and Sugden P.H. Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses. J. Cell. Physiol. 212 (2007) 311-322
14. Feinberg M.W., Lin Z., Fisch S., and Jain M.K. An emerging role for Krüppel-like factors in vascular biology. Trends Cardiovasc. Med. 14 (2004) 241-246.
15. Atkins G.B., and Jain M.K. Role of Krüppel-like transcription factors in endothelial biology. Circ. Res. 100 (2007) 1686-1695
16. Wani M.A., Conkright M.D., Jeffries S., Hughes M.J., and Lingrel J.B. cDNA isolation, genomic structure, regulation, and chromosomal localization of human lung Kruppel-like factor. Genomics 60 (1999) 78-86
17. Haldar S.M., Ibrahim O.A., and Jain M.K. Kruppel-like factors (KLFs) in muscle biology. J. Mol. Cell. Cardiol. 43 (2007) 1-10
18. Scohy S., Gabant P., Van Reeth T., Hertveldt V., Drèze P.-L., Van Vooren P., Rivière M., Szpirer J., and Szpirer C. Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family. Genomics 70 (2000) 93-101
19. Lavallée G., Andelfinger G., Nadeau M., Lefebvre C., Nemer G., Horb M.E., and Nemer M. The Krüppel-like transcription factor KLF13 is a novel regulator of heart development. EMBO J. 25 (2006) 5201-5213
20. Uchida S., Tanaka Y., Ito H., Saitoh-Ohara F., Inazawa J., Yokoyama K.K., Sasaki S., and Marumo F. Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor. Mol. Cell. Biol. 20 (2000) 7319-7331
21. Fisch S., Gray S., Heymans S., Haldar S.M., Wang B., Pfister O., Cui L., Kumar A., Lin Z., Sen-Banerjee S., Das C.A., Petersen H., Mende U., Burleigh B.A., Zhu Y., Pinto Y.M., Liao R., and Jain M.K. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 7074-7079
22. 2 in cardiac myocytes. Biochem. Biophys. Res. Commun. 307 (2003) 416-421
23. 2-induced apoptosis. Physiol. Genomics 29 (2007) 118-127
24. Kennedy R.A., Kemp T.J., Sugden P.H., and Clerk A. Using U0126 to dissect the role of the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade in the regulation of gene expression by endothelin-1 in cardiac myocytes. J. Mol. Cell. Cardiol. 41 (2006) 236-247
25. Cullingford T.E., Markou T., Fuller S.J., Giraldo A., Pikkarainen S., Zoumpoulidou G., Alsafi A., Ekere C., Kemp T.J., Dennis J.L., Game L., Sugden P.H., and Clerk A. Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes. Genome Biol. 9 (2008) R32.
26. 1-mediated response. J. Biol. Chem. 265 (1990) 13809-13817
27. Bogoyevitch M.A., Clerk A., and Sugden P.H. Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes. Biochem. J. 309 (1995) 437-443
28. Clerk A., Harrison J.G., Long C.S., and Sugden P.H. Pro-inflammatory cytokines stimulate mitogen-activated protein kinases, increase phosphorylation of c-Jun and ATF2 and upregulated c-Jun protein in neonatal rat ventricular myocytes. J. Mol. Cell. Cardiol. 31 (1999) 2087-2099
29. Markou T., Cullingford T.E., Giraldo A., Weiss S.C., Alsafi A., Fuller S.J., Clerk A., and Sugden P.H. Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition. Cell. Signal. 20 (2008) 206-218
30. Kyriakis J.M., and Avruch J. pp54 Microtubule-associated protein 2 kinase. A novel serine/threonine kinase regulated by phosphorylation and stimulated by poly-l-lysine. J. Biol. Chem. 265 (1990) 17355-17363
31. Moriguchi T., Kuroyanagi N., Yamaguchi K., Gotoh Y., Irie K., Kano T., Shirakabe K., Muro Y., Shibuya H., Matsumoto K., Nishida E., and Hagiwara M. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J. Biol. Chem. 271 (1996) 13675-13679
32. Clerk A., Aggeli I.-K.S., Stathopoulou K., and Sugden P.H. Peptide growth factors signal differentially through protein kinase C to extracellular signal-regulated kinase in neonatal cardiomyocytes. Cell. Signal. 18 (2006) 225-235
33. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., and Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273 (1998) 18623-18632
34. Davies S.P., Reddy H., Caivano M., and Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351 (2000) 95-105
35. Mody N., Leitch J., Armstrong C., Dixon J., and Cohen P. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. FEBS Lett. 502 (2001) 21-24
36. van Thienen J.V., Fiedderus J.O., Dekker R.J., Rohlena J., van Ijzendoorn G.A., Kootstra N.A., Pannekoek H., and Horrevoets A.J. Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization. Cardiovasc. Res. 72 (2006) 231-240
37. Clerk A., Michael A., and Sugden P.H. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?. J. Cell Biol. 142 (1998) 523-535
38. Pham F.H., Sugden P.H., and Clerk A. Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes. Circ. Res. 86 (2000) 1252-1258
39. Bilanges B., and Stokoe D. Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies. Oncogene 26 (2007) 5973-5990
40. Leung A.K., and Sharp P.A. Function and localization of microRNAs in mammalian cells. Cold Spring Harbor Symp. Quant. Biol. 71 (2006) 29-38
41. Cook S.A., Sugden P.H., and Clerk A. Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ. Res. 85 (1999) 940-949
42. Clerk A., Michael A., and Sugden P.H. Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytes. Biochem. J. 333 (1998) 581-589
43. Clerk A., Bogoyevitch M.A., Andersson M.B., and Sugden P.H. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J. Biol. Chem. 269 (1994) 32848-32857
44. Boon R.A., Fledderus J.O., Volger O.L., van Wanrooij E.J.A., Pardali E., Weesie F., Kuiper J., Pannekoek H., ten Dijke P., and Horrevoets A.J.G. KLF2 suppresses TGF-β signaling in endothelium through induction of Smad7 and inhibition of AP-1. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 532-539
45. Hamik A., Lin Z., Kumar A., Balcells M., Sinha S., Katz J., Feinberg M.W., Gerszten R.E., Edelman E.R., and Jain M.K. Kruppel-like factor 4 regulates endothelial inflammation. J. Biol. Chem. 282 (2007) 13769-13779
46. Sohn S.J., Li D., Lee L.K., and Winoto A. Transcriptional regulation of tissue-specific genes by ERK5 mitogen-activated protein kinase. Mol. Cell. Biol. 25 (2005) 8553-8566
47. Ornatsky O.I., Cox D.M., Tangirala P., Andreucci J.J., Quinn Z.A., Wrana J.L., Prywes R., Yu Y.T., and McDermott J.C. Post-translational control of the MEF2A transcriptional regulatory protein. Nucleic Acids Res. 27 (1999) 2646-2654
48. Ahmad N., and Lingrel J.B. Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases. Biochemistry 44 (2005) 6276-6285
49. Harrison J.G., Sugden P.H., and Clerk A. Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal rat cardiac myocytes: implications for the regulation of c-jun expression. Biochim. Biophys. Acta 1644 (2004) 17-25
50. 2 up-regulates Krüppel-like factor 4 expression independently of peroxisome proliferators-activated receptor γ by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells. Mol. Pharmacol. 68 (2005) 1203-1213
51. Liu Y., Sinha S., McDonald O.G., Shang Y., Hoofnagle M.H., and Owens G.K. Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. J. Biol. Chem. 280 (2005) 9719-9727
52. Inuzuka H., Wakao H., Masuho Y., Tojo H., and Nanbu-Wakao R. cDNA cloning and expression analysis of mouse zf9, a Krüppel-like transcription factor gene that is induced by adipogenic hormonal stimulation in 3T3-L1 cells. Biochim. Biophys. Acta 1447 (1999) 199-207
53. Kojima S., Hayashi S., Shimokado K., Suzuki Y., Shimada J., Crippa M.P., and Friedman S.L. Transcriptional activation of urokinase by the Krüppel-like factor Zf9/COPEB activates latent TGF-β1 in vascular endothelial cells. Blood 95 (2000) 1309-1316
54. Kawai-Kowase K., Kurabayashi M., Hoshino Y., Ohyama Y., and Nagai R. Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells. Circ. Res. 85 (1999) 787-795.
55. Sun R., Chen X., and Yang V.W. Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation. J. Biol. Chem. 276 (2001) 6897-6900
56. Pham F.H., Cole S.M., and Clerk A. Regulation of cardiac myocyte protein synthesis through phosphatidylinositol 3′ kinase and protein kinase B. Adv. Enzyme Regul. 41 (2001) 73-86