-
1
-
-
0025754446
-
Death by suicide: One-way to go in mammalian cellular development?
-
Ucker, D.S. Death by suicide: One-way to go in mammalian cellular development? New Biol., 1991, 3, 103-109.
-
(1991)
New Biol
, vol.3
, pp. 103-109
-
-
Ucker, D.S.1
-
2
-
-
21644480008
-
High level expression of apoptosis inhibitor in hepatoma cell line expressing Hepatitis B virus
-
Lu, X.; Lee, M.; Tran, T.; Block, T. High level expression of apoptosis inhibitor in hepatoma cell line expressing Hepatitis B virus. Int. J. Med. Sci., 2005, 2, 30-35.
-
(2005)
Int. J. Med. Sci
, vol.2
, pp. 30-35
-
-
Lu, X.1
Lee, M.2
Tran, T.3
Block, T.4
-
3
-
-
0028559019
-
Programmed cell death in Drosophila
-
Steller, H.; Grether, M.E. Programmed cell death in Drosophila. Neuron, 1994, 13, 1269-1274.
-
(1994)
Neuron
, vol.13
, pp. 1269-1274
-
-
Steller, H.1
Grether, M.E.2
-
4
-
-
33947209622
-
DNA mismatch repair initiates 6-thioguanine - induced autophagy through p53 activation in human tumor cells
-
Zeng, X.; Yan, T.; Schupp, J.E.; Seo, Y.; Kinsella, T.J. DNA mismatch repair initiates 6-thioguanine - induced autophagy through p53 activation in human tumor cells. Clin. Cancer Res., 2007, 13, 1315-1321.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1315-1321
-
-
Zeng, X.1
Yan, T.2
Schupp, J.E.3
Seo, Y.4
Kinsella, T.J.5
-
5
-
-
0343262714
-
Choosing anticancer drug targets in the postgenomic era
-
Kaelin, W.G. Jr. Choosing anticancer drug targets in the postgenomic era. J. Clin. Invest., 1999, 104, 1503-1506.
-
(1999)
J. Clin. Invest
, vol.104
, pp. 1503-1506
-
-
Kaelin Jr., W.G.1
-
6
-
-
0033761712
-
The inhibitors of apoptosis of Epiphyas postvittana nucleopolyhedrovirus
-
Maguire, T.; Harrison, P.; Hyink, O.; Kalmakoff, J.; Ward, V.K. The inhibitors of apoptosis of Epiphyas postvittana nucleopolyhedrovirus. J. Gen. Virol., 2000, 81, 2803-2811.
-
(2000)
J. Gen. Virol
, vol.81
, pp. 2803-2811
-
-
Maguire, T.1
Harrison, P.2
Hyink, O.3
Kalmakoff, J.4
Ward, V.K.5
-
7
-
-
0036144421
-
Hyperphosphorylation of histone H2A.X and dephosphorylation of histone H1 subtypes in the course of apoptosis
-
Talasz, H.; Helliger, W.; Sarg, B.; Debbage, P.L.; Puschendorf, B.; Lindner, H. Hyperphosphorylation of histone H2A.X and dephosphorylation of histone H1 subtypes in the course of apoptosis. Cell Death Differ., 2002, 9, 27-39.
-
(2002)
Cell Death Differ
, vol.9
, pp. 27-39
-
-
Talasz, H.1
Helliger, W.2
Sarg, B.3
Debbage, P.L.4
Puschendorf, B.5
Lindner, H.6
-
8
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell, 1997, 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
9
-
-
0032411599
-
Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress
-
Amundson, S.A.; Myers, T.G.; Fornace, A.J. Jr. Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress. Oncogene, 1998, 17, 3287-3299.
-
(1998)
Oncogene
, vol.17
, pp. 3287-3299
-
-
Amundson, S.A.1
Myers, T.G.2
Fornace Jr., A.J.3
-
10
-
-
0042415612
-
Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage
-
Joseph, T.W.; Zaika, A.; Moll, U.M. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage. FASEB J., 2003, 17, 1622-1630.
-
(2003)
FASEB J
, vol.17
, pp. 1622-1630
-
-
Joseph, T.W.1
Zaika, A.2
Moll, U.M.3
-
11
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara, M.; Erster, S.; Zaika, A.; Petrenko, O.; Chittenden, T.; Pancoska, P.; Moll, U.M. p53 has a direct apoptogenic role at the mitochondria. Mol. Cell, 2003, 11, 577-590.
-
(2003)
Mol. Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
12
-
-
0035399927
-
A distinct pathway of cell-mediated apoptosis initiated by granulysin
-
Kaspar, A.A.; Okada, S.; Kumar, J.; Poulain, F.R.; Drouvalakis, K.A.; Kelekar, A.; Hanson, D.A.; Kluck, R.M.; Hitoshi, Y.; Johnson, D.E.; Froelich, C.J.; Thompson, C.B.; Newmeyer, D.D.; Anel, A.; Clayberger, C.; Krensky, A.M. A distinct pathway of cell-mediated apoptosis initiated by granulysin. J. Immunol., 2001, 167, 350-356.
-
(2001)
J. Immunol
, vol.167
, pp. 350-356
-
-
Kaspar, A.A.1
Okada, S.2
Kumar, J.3
Poulain, F.R.4
Drouvalakis, K.A.5
Kelekar, A.6
Hanson, D.A.7
Kluck, R.M.8
Hitoshi, Y.9
Johnson, D.E.10
Froelich, C.J.11
Thompson, C.B.12
Newmeyer, D.D.13
Anel, A.14
Clayberger, C.15
Krensky, A.M.16
-
13
-
-
0346365081
-
Apoptosis inhibitors for heart disease
-
Webster, K.A.; Bishopric, N.H. Apoptosis inhibitors for heart disease. Circulation, 2003, 108, 2954-2956.
-
(2003)
Circulation
, vol.108
, pp. 2954-2956
-
-
Webster, K.A.1
Bishopric, N.H.2
-
15
-
-
33748764392
-
The CD40-induced protection against CD95-mediated apoptosis is associated with a rapid upregulation of anti-apoptotic c-FLIP
-
Eeva, J.; Ropponen, A.; Nuutinen, U.; Eeva, S.-T. Matto, M.; Eray, M.; Pelkonen, J. The CD40-induced protection against CD95-mediated apoptosis is associated with a rapid upregulation of anti-apoptotic c-FLIP. Mol. Immunol., 2007, 44, 1230-1237.
-
(2007)
Mol. Immunol
, vol.44
, pp. 1230-1237
-
-
Eeva, J.1
Ropponen, A.2
Nuutinen, U.3
Eeva, S.-T.4
Matto, M.5
Eray, M.6
Pelkonen, J.7
-
16
-
-
33644673642
-
Structural details on mdm2-p53 interaction
-
Chi, S.W.; Lee, S.H.; Kim, D.H.; Ahn, M.J.; Kim, J.S.; Woo, J.Y.; Torizawa, T.; Kainosho, M.; Han, K.H. Structural details on mdm2-p53 interaction. J. Biol. Chem., 2005, 280, 38795-38802.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 38795-38802
-
-
Chi, S.W.1
Lee, S.H.2
Kim, D.H.3
Ahn, M.J.4
Kim, J.S.5
Woo, J.Y.6
Torizawa, T.7
Kainosho, M.8
Han, K.H.9
-
17
-
-
0035970081
-
DNA replication blockade impairs p53-transactivation
-
Takimoto, R.; El-Deiry, W.S. DNA replication blockade impairs p53-transactivation. P. Natl. Acad. Sci. USA, 2001, 98, 781-783.
-
(2001)
P. Natl. Acad. Sci. USA
, vol.98
, pp. 781-783
-
-
Takimoto, R.1
El-Deiry, W.S.2
-
18
-
-
43049163953
-
Acetylation is indispensable for p53 activation
-
Tang, Y.; Zhao, W.; Chen, Y.; Zhao, Y.; Gu, W. Acetylation is indispensable for p53 activation. Cell, 2008, 133, 612-626.
-
(2008)
Cell
, vol.133
, pp. 612-626
-
-
Tang, Y.1
Zhao, W.2
Chen, Y.3
Zhao, Y.4
Gu, W.5
-
19
-
-
33745142870
-
Iminotetrahydro-benzothiazole derivatives as p53 inhibitors: Discovery of a highly potent in vivo inhibitor and its action mechanism
-
Pietrancosta, N.; Moumen, A.; Dono, R.; Lingor, P.; Planchamp, V.; Lamballe, F.; Bahr, M.; Kraus, J.L.; Maina, F. Iminotetrahydro-benzothiazole derivatives as p53 inhibitors: Discovery of a highly potent in vivo inhibitor and its action mechanism. J. Med. Chem., 2006, 49, 3645-3652.
-
(2006)
J. Med. Chem
, vol.49
, pp. 3645-3652
-
-
Pietrancosta, N.1
Moumen, A.2
Dono, R.3
Lingor, P.4
Planchamp, V.5
Lamballe, F.6
Bahr, M.7
Kraus, J.L.8
Maina, F.9
-
20
-
-
34447258120
-
DNA damage, p53, apoptosis and vascular disease
-
Mercer, J.; Mahmoudi, M.; Bennett, M. DNA damage, p53, apoptosis and vascular disease. Mutat. Res., 2007, 621, 75-86
-
(2007)
Mutat. Res
, vol.621
, pp. 75-86
-
-
Mercer, J.1
Mahmoudi, M.2
Bennett, M.3
-
21
-
-
0032478314
-
Fatty acid-induced β cell apoptosis: A link between obesity and diabetes
-
Shimabukuro, M.; Zhou, Y.-T.; Levi, M.; Unger, R.H. Fatty acid-induced β cell apoptosis: A link between obesity and diabetes. P. Natl. Acad. Sci. USA, 1998, 95, 2498-2502.
-
(1998)
P. Natl. Acad. Sci. USA
, vol.95
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.-T.2
Levi, M.3
Unger, R.H.4
-
22
-
-
0036829557
-
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
-
Duan, W.; Zhu, X.; La denheim, B.; Yu, Q.S.; Guo, Z.; Oyler, J.; Cutler, R.G.; Cadet, J.L.; Greig, N.H.; Mattson, M.P. p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. Ann. Neurol., 2002, 52, 597-606.
-
(2002)
Ann. Neurol
, vol.52
, pp. 597-606
-
-
Duan, W.1
Zhu, X.2
La denheim, B.3
Yu, Q.S.4
Guo, Z.5
Oyler, J.6
Cutler, R.G.7
Cadet, J.L.8
Greig, N.H.9
Mattson, M.P.10
-
23
-
-
33747038451
-
Interventional strategies to prevent beta-cell apoptosis in islet transplantation
-
Emamaullee, J.A.; Shapiro, A.M. J. Interventional strategies to prevent beta-cell apoptosis in islet transplantation. Diabetes, 2006, 55, 1907-1914.
-
(1907)
Diabetes
, vol.2006
, pp. 55
-
-
Emamaullee, J.A.1
Shapiro, A.M.J.2
-
24
-
-
40549140725
-
Protective effect of p53 in vascular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2
-
Kim, Y.-M.; Choi, B.-M.; Kim, Y.-S.; Kwon, Y.-G.; Kibbe, M.R.; Billiar, T.R.; Tzeng, E. Protective effect of p53 in vascular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2. BMB Rep., 2008, 41, 164-169.
-
(2008)
BMB Rep
, vol.41
, pp. 164-169
-
-
Kim, Y.-M.1
Choi, B.-M.2
Kim, Y.-S.3
Kwon, Y.-G.4
Kibbe, M.R.5
Billiar, T.R.6
Tzeng, E.7
-
25
-
-
5644259587
-
-
Schimmer, A.D. Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice. Cancer Res., 2004, 64, 7183-7190.
-
Schimmer, A.D. Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice. Cancer Res., 2004, 64, 7183-7190.
-
-
-
-
26
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni, A.; Brunet, A.; West, A.E.; Datta, S.R.; Takasu, M.A.; Greenberg, M.E. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science, 1999, 286, 1358-1362.
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
27
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone, R.W.; Lowe, S.W. Apoptosis: A link between cancer genetics and chemotherapy. Cell, 2002, 108, 153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Lowe, S.W.2
-
28
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk, J.E.; Kuwana, T.; Bouchier-Hayes, L.; Droin, N.M.; Newmeyer, D.D.; Schuler, M.; Green, D.R. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science, 2004, 303, 1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
29
-
-
0033992478
-
p53 and human cancer: The first ten thousand mutations
-
Hainaut, P.; Hollstein, M. p53 and human cancer: The first ten thousand mutations. Adv. Cancer Res., 2000, 77, 81-137.
-
(2000)
Adv. Cancer Res
, vol.77
, pp. 81-137
-
-
Hainaut, P.1
Hollstein, M.2
-
30
-
-
0033579412
-
Regulation of the p53 tumor suppressor protein
-
Oren, M. Regulation of the p53 tumor suppressor protein. J. Biol. Chem., 1999, 274, 36031-36034.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 36031-36034
-
-
Oren, M.1
-
31
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden, K.H.; Lu, X. Live or let die: The cell's response to p53. Nat. Rev. Cancer, 2002, 2, 594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
32
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
Hoffman, W.H.; Biade, S.; Zilfou, J.T.; Chen, J.; Murphy, M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J. Biol. Chem., 2002, 277, 3247-3257
-
(2002)
J. Biol. Chem
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Zilfou, J.T.3
Chen, J.4
Murphy, M.5
-
33
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
Brooks, C.L.; Gu, W. p53 ubiquitination: Mdm2 and beyond. Mol. Cell, 2006, 21, 307-315.
-
(2006)
Mol. Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
34
-
-
65249100143
-
Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: A novel approach for cancer therapy
-
Shangary, S.; Wang, S. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: A novel approach for cancer therapy. Ann. Rev. Pharmacol. Toxicol., 2009, 49, 223-241.
-
(2009)
Ann. Rev. Pharmacol. Toxicol
, vol.49
, pp. 223-241
-
-
Shangary, S.1
Wang, S.2
-
35
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
Szak, S.T.; Mays D.; Pietenpol, J.A. Kinetics of p53 binding to promoter sites in vivo. Mol. Cell. Biol., 2001, 21, 3375-3386.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
36
-
-
22244486994
-
The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53
-
Higashitsuji, H.; Higashitsuji, H.; Itoh, K.; Sakurai, T.; Nagao, T.; Sumitomo, H.; Masuda, T.; Dawson, S.; Shimada, Y.; Mayer, R.J.; Fujita, J. The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53. Cancer Cell, 2005, 8, 75-87.
-
(2005)
Cancer Cell
, vol.8
, pp. 75-87
-
-
Higashitsuji, H.1
Higashitsuji, H.2
Itoh, K.3
Sakurai, T.4
Nagao, T.5
Sumitomo, H.6
Masuda, T.7
Dawson, S.8
Shimada, Y.9
Mayer, R.J.10
Fujita, J.11
-
37
-
-
38049046724
-
NUMB controls p53 tumour suppressor activity
-
Colaluca, I.N.; Tosoni, D.; Nuciforo, P.; Senic-Matuglia, F.; Galimberti, V.; Viale, G.; Pece, S.; Di Fiore, P.P. NUMB controls p53 tumour suppressor activity. Nature, 2008, 451, 76-80.
-
(2008)
Nature
, vol.451
, pp. 76-80
-
-
Colaluca, I.N.1
Tosoni, D.2
Nuciforo, P.3
Senic-Matuglia, F.4
Galimberti, V.5
Viale, G.6
Pece, S.7
Di Fiore, P.P.8
-
38
-
-
0035078837
-
Inactivation of Myc-induced p53-dependent apoptosis in human tumors
-
Henriksson, M.; Selivanova, G.; Lindstrom, M.; Wiman, K.G. Inactivation of Myc-induced p53-dependent apoptosis in human tumors. Apoptosis, 2001, 6, 133-137.
-
(2001)
Apoptosis
, vol.6
, pp. 133-137
-
-
Henriksson, M.1
Selivanova, G.2
Lindstrom, M.3
Wiman, K.G.4
-
39
-
-
0242319666
-
Apoptosis - the p53 network
-
Haupt, S.; Berger, M.; Goldberg, Z.; Haupt, Y. Apoptosis - the p53 network. J. Cell Sci., 2003, 116, 4077-4085.
-
(2003)
J. Cell Sci
, vol.116
, pp. 4077-4085
-
-
Haupt, S.1
Berger, M.2
Goldberg, Z.3
Haupt, Y.4
-
40
-
-
0033569422
-
-
Eischen, C.M.; Weber, J.D.; Roussel, M.F.; Sherr, C.J.; Cleveland, J.L. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Gene Dev., 1999, 13, 2658- 669.
-
Eischen, C.M.; Weber, J.D.; Roussel, M.F.; Sherr, C.J.; Cleveland, J.L. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Gene Dev., 1999, 13, 2658- 669.
-
-
-
-
41
-
-
0035859956
-
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
-
Harada, H.; Andersen, J.S.; Mann, M.; Terada, N.; Korsmeyer, S.J. p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. P. Natl. Acad. Sci. USA, 2001, 98, 9666-9670.
-
(2001)
P. Natl. Acad. Sci. USA
, vol.98
, pp. 9666-9670
-
-
Harada, H.1
Andersen, J.S.2
Mann, M.3
Terada, N.4
Korsmeyer, S.J.5
-
42
-
-
0036710512
-
The PTEN, Mdm2, p53 tumor suppressoroncoprotein network
-
Mayo, L.D.; Donner, D.B. The PTEN, Mdm2, p53 tumor suppressoroncoprotein network. Trends Biochem. Sci., 2002, 27, 462-467
-
(2002)
Trends Biochem. Sci
, vol.27
, pp. 462-467
-
-
Mayo, L.D.1
Donner, D.B.2
-
43
-
-
0034826553
-
Modulation of p53 function in cellular regulation
-
Appella, E. Modulation of p53 function in cellular regulation. Eur. J. Biochem., 2001, 268, 2763-2764.
-
(2001)
Eur. J. Biochem
, vol.268
, pp. 2763-2764
-
-
Appella, E.1
-
44
-
-
0038745821
-
Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas
-
Herr, I.; Ucur, E.; Herzer, K.; Okouoyo, S.; Ridder, R.; Krammer, P.H.; von Knebel Doeberitz, M.; Debatin, K.M. Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas. Cancer Res., 2003, 63, 3112-3120.
-
(2003)
Cancer Res
, vol.63
, pp. 3112-3120
-
-
Herr, I.1
Ucur, E.2
Herzer, K.3
Okouoyo, S.4
Ridder, R.5
Krammer, P.H.6
von Knebel Doeberitz, M.7
Debatin, K.M.8
-
45
-
-
0033543728
-
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
-
Komarov, P.G.; Komarova, E.A.; Kondratov, R.V.; Christov-Tselkov, K.; Coon, J.S.; Chernov, M.V.; Gudkov, A.V. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science, 1999, 285, 1733-1737.
-
(1733)
Science
, vol.1999
, pp. 285
-
-
Komarov, P.G.1
Komarova, E.A.2
Kondratov, R.V.3
Christov-Tselkov, K.4
Coon, J.S.5
Chernov, M.V.6
Gudkov, A.V.7
-
46
-
-
2342491481
-
The role of p53-induced apoptosis in cerebral ischemia: Effects of the p53 inhibitor pifithrin alpha
-
Leker, R.R.; Ahronowiz, M.; Greig, N.H.; Ovadia, H. The role of p53-induced apoptosis in cerebral ischemia: Effects of the p53 inhibitor pifithrin alpha. Exp. Neurol., 2004, 187, 487-486
-
(2004)
Exp. Neurol
, vol.187
, pp. 487-486
-
-
Leker, R.R.1
Ahronowiz, M.2
Greig, N.H.3
Ovadia, H.4
-
47
-
-
33747056618
-
Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats
-
Endo, H.; Kamada, H.; Nito, C.; Nishi, T.; Chan, P.H. Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats. J. Neurosci., 2006, 26, 7974-7983.
-
(2006)
J. Neurosci
, vol.26
, pp. 7974-7983
-
-
Endo, H.1
Kamada, H.2
Nito, C.3
Nishi, T.4
Chan, P.H.5
-
48
-
-
0035085210
-
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide
-
Culmsee, C.; Zhu, X.; Yu, Q.S.; Chan, S.L.; amandola, S.; Guo, Z.; Greig, N.H.; Mattson, M.P. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide. J. Neurochem., 2001, 77, 220-228
-
(2001)
J. Neurochem
, vol.77
, pp. 220-228
-
-
Culmsee, C.1
Zhu, X.2
Yu, Q.S.3
Chan, S.L.4
amandola, S.5
Guo, Z.6
Greig, N.H.7
Mattson, M.P.8
-
49
-
-
0037507247
-
p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways
-
Komarova, E.A.; Neznanov, N.; Komarov, P.G.; Chernov, M.V.; Wang, K.; Gudkov, A.V. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. J. Biol. Chem., 2003, 278, 15465-15468.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 15465-15468
-
-
Komarova, E.A.1
Neznanov, N.2
Komarov, P.G.3
Chernov, M.V.4
Wang, K.5
Gudkov, A.V.6
-
50
-
-
26444495595
-
Inhibitors of apoptosis in lymphocytes: Synthesis and biological evaluation of compounds related to pifithrin-alpha
-
Barchechath, S.D.; Tawatao, R.I.; Corr, M.; Carson, D.A.; Cottam, H.B. Inhibitors of apoptosis in lymphocytes: Synthesis and biological evaluation of compounds related to pifithrin-alpha. J. Med. Chem., 2005, 48, 6409-6422.
-
(2005)
J. Med. Chem
, vol.48
, pp. 6409-6422
-
-
Barchechath, S.D.1
Tawatao, R.I.2
Corr, M.3
Carson, D.A.4
Cottam, H.B.5
-
51
-
-
0015101125
-
Interdependence between physical parameters and selection of substituent groups for correlation studies
-
Zhu, X.; Yu, Q.-S.; Culter, R.G.; Culmsee, C.W.; Holloway, H.W.; Lahiri, D.K.; Mattson, M.P.; Greig, N.H. Interdependence between physical parameters and selection of substituent groups for correlation studies. J. Med. Chem., 1971, 14, 680-684.
-
(1971)
J. Med. Chem
, vol.14
, pp. 680-684
-
-
Zhu, X.1
Yu, Q.-S.2
Culter, R.G.3
Culmsee, C.W.4
Holloway, H.W.5
Lahiri, D.K.6
Mattson, M.P.7
Greig, N.H.8
-
52
-
-
29544434723
-
The p53 inhibitor pifithrin-alpha forms a sparingly soluble derivative via intramolecular cyclization under physiological conditions
-
Gary, R.K.; Jensen, D.A. The p53 inhibitor pifithrin-alpha forms a sparingly soluble derivative via intramolecular cyclization under physiological conditions. Mol. Pharmaceutics, 2005, 2, 462-474.
-
(2005)
Mol. Pharmaceutics
, vol.2
, pp. 462-474
-
-
Gary, R.K.1
Jensen, D.A.2
-
53
-
-
33644667621
-
An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines
-
Walton, M.I.; Wilson, S.C.; Hardcastle, I.R.; Mirza, A.R.; Workman, P. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines. Mol. Cancer Ther., 2005, 4, 1369-1377.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 1369-1377
-
-
Walton, M.I.1
Wilson, S.C.2
Hardcastle, I.R.3
Mirza, A.R.4
Workman, P.5
-
54
-
-
0024554933
-
Molecular similarity: A basis for designing drug screening programs
-
Johnson, M.; Lajiness, M.; Maggiora, G. Molecular similarity: A basis for designing drug screening programs. Prog. Clin. Biol. Res., 1989, 291, 167-171.
-
(1989)
Prog. Clin. Biol. Res
, vol.291
, pp. 167-171
-
-
Johnson, M.1
Lajiness, M.2
Maggiora, G.3
-
55
-
-
0024239320
-
Methods for drug discovery: Development of potent, selective, orally effective cholecystokinin antagonists
-
Evans, B.E.; Rittle, K.E.; Bock, M.G.; DiPardo, R.M.; Freidinger, R.M.; Whitter, W.L.; Lundell, G.F.; Veber, D.F.; Anderson, P.S.; Chang, R.S.L.; Lotti, V.J.; Cerino, D.J.; Chen, T.B.;Kling, P.J.;Kunkel, K.A.; Springer, J.P.; Hirshfield, J. Methods for drug discovery: Development of potent, selective, orally effective cholecystokinin antagonists. J. Med. Chem., 1988, 31, 2235-2246.
-
(1988)
J. Med. Chem
, vol.31
, pp. 2235-2246
-
-
Evans, B.E.1
Rittle, K.E.2
Bock, M.G.3
DiPardo, R.M.4
Freidinger, R.M.5
Whitter, W.L.6
Lundell, G.F.7
Veber, D.F.8
Anderson, P.S.9
Chang, R.S.L.10
Lotti, V.J.11
Cerino, D.J.12
Chen, T.B.13
Kling, P.J.14
Kunkel, K.A.15
Springer, J.P.16
Hirshfield, J.17
-
56
-
-
14644425180
-
Novel cyclized Pifithrin-alpha p53 inactivators: Synthesis and biological studies
-
Pietrancosta, N.; Maina, F.; Dono, R.; Moumen, A.; Garino, C.; Laras, Y.; Burlet, S.; Quelever, G.; Kraus, J.L. Novel cyclized Pifithrin-alpha p53 inactivators: Synthesis and biological studies. Bioorg. Med. Chem. Lett., 2005, 15, 1561-1564.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 1561-1564
-
-
Pietrancosta, N.1
Maina, F.2
Dono, R.3
Moumen, A.4
Garino, C.5
Laras, Y.6
Burlet, S.7
Quelever, G.8
Kraus, J.L.9
-
57
-
-
3242690522
-
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
-
Erster, S.; Mihara, M.; Kim, R.H.; Petrenko, O.; Moll, U.M. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell Biol., 2004, 24, 6728-6741
-
(2004)
Mol. Cell Biol
, vol.24
, pp. 6728-6741
-
-
Erster, S.1
Mihara, M.2
Kim, R.H.3
Petrenko, O.4
Moll, U.M.5
-
58
-
-
0036121363
-
p53 regulation of DNA excision repair pathways
-
Smith, M.L.; Seo, Y.R. p53 regulation of DNA excision repair pathways. Mutagenesis, 2002, 17, 149-156.
-
(2002)
Mutagenesis
, vol.17
, pp. 149-156
-
-
Smith, M.L.1
Seo, Y.R.2
-
59
-
-
33747620737
-
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
-
Strom, E.; Sathe, S.; Kamarov, P.G.; Chernova, O.B.; Pavlovska, I.; Shyshynova, I.; Bosykh, D.A.; Burdelya, L.G.; Macklis, R.M.; Skaliter, R.; Komarowa, E.A.;Gudkov, A.V. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat. Chem. Biol., 2004, 2, 474-479.
-
(2004)
Nat. Chem. Biol
, vol.2
, pp. 474-479
-
-
Strom, E.1
Sathe, S.2
Kamarov, P.G.3
Chernova, O.B.4
Pavlovska, I.5
Shyshynova, I.6
Bosykh, D.A.7
Burdelya, L.G.8
Macklis, R.M.9
Skaliter, R.10
Komarowa, E.A.11
Gudkov, A.V.12
-
60
-
-
34547803770
-
Dangerous habits of a security guard: The two faces of p53 as a drug target
-
Gudkov, A.V.; Komarova, E.A. Dangerous habits of a security guard: The two faces of p53 as a drug target. Hum. Mol. Genet., 2007, 16, R67-R72.
-
(2007)
Hum. Mol. Genet
, vol.16
-
-
Gudkov, A.V.1
Komarova, E.A.2
-
61
-
-
33747620737
-
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
-
Sathe, S.E.; Komarov, P.G.; Chernova, O.B.; Pavlovska, I.; Shyshynova, I.; Bosykh, D.A.; Burdelya, L.G.; Macklis, R.M.; Skaliter, R.; Komarova, E.A.; Gudkov, A.V. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat. Chem. Biol., 2006, 2, 474-479.
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 474-479
-
-
Sathe, S.E.1
Komarov, P.G.2
Chernova, O.B.3
Pavlovska, I.4
Shyshynova, I.5
Bosykh, D.A.6
Burdelya, L.G.7
Macklis, R.M.8
Skaliter, R.9
Komarova, E.A.10
Gudkov, A.V.11
-
62
-
-
0037113913
-
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells
-
Zhang, H.; Shi, X.; Zhang, Q.-J.; Hampong, M.; Harry Paddon, H.; Wahyuningsih, D.; Pelech, S. Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. J. Biol. Chem., 2002, 277, 43648-43658.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 43648-43658
-
-
Zhang, H.1
Shi, X.2
Zhang, Q.-J.3
Hampong, M.4
Harry Paddon, H.5
Wahyuningsih, D.6
Pelech, S.7
-
63
-
-
0035950547
-
Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells
-
Sayed, M.; Pelech, S.L.; Wong, C.; Marotta, A.; Salh, B. Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells. Oncogene, 2001, 20, 6994-7005
-
(2001)
Oncogene
, vol.20
, pp. 6994-7005
-
-
Sayed, M.1
Pelech, S.L.2
Wong, C.3
Marotta, A.4
Salh, B.5
-
64
-
-
0029907683
-
The preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies by amifostine (Ethyol)
-
Capizzi, R.L. The preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies by amifostine (Ethyol). Eur. J. Cancer, 1996, 32A, S5-S16.
-
(1996)
Eur. J. Cancer
, vol.32 A
-
-
Capizzi, R.L.1
-
65
-
-
0642349138
-
Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells
-
Acosta, J.C.; Richard, C.; Delgado, M.D.; Horita, M.; Rizzo, M.G.; Fernandez-Luna, J.L.; Leon, J. Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells. Mol. Cancer Ther., 2003, 2, 893-900.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 893-900
-
-
Acosta, J.C.1
Richard, C.2
Delgado, M.D.3
Horita, M.4
Rizzo, M.G.5
Fernandez-Luna, J.L.6
Leon, J.7
-
66
-
-
0003700389
-
-
McEvoy, G.K. Editor, Bethesda, Maryland: American Society of Health-System Pharmacists, Inc
-
McEvoy, G.K. Editor. AHFS 2002 Drug Information. Bethesda, Maryland: American Society of Health-System Pharmacists, Inc.; 2002.
-
(2002)
AHFS 2002 Drug Information
-
-
-
67
-
-
0033014520
-
Chemoprotectants: A review of their clinical pharmacology and therapeutic efficacy
-
Links, M.; Lewis, C. Chemoprotectants: A review of their clinical pharmacology and therapeutic efficacy. Drugs, 1999, 57, 293308.
-
(1999)
Drugs
, vol.57
, pp. 293308
-
-
Links, M.1
Lewis, C.2
-
68
-
-
26444434342
-
Pharmacological manipulation of cell death: Clinical applications in sight?
-
Green, D.R.; Kroemer, G. Pharmacological manipulation of cell death: clinical applications in sight? J. Clin. Invest., 2005, 115, 2610-2617.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 2610-2617
-
-
Green, D.R.1
Kroemer, G.2
-
69
-
-
0034284015
-
Poor prognosis acute myelogenous leukemia 2 - biological and molecular biological characteristics and treatment outcome
-
Li, B.; Yang, J.; Tao, M.; Nayini, J.; Horvath, E.; Chopra, H.; Meyer, P.; Venugopal, P.; Preisler, H.D. Poor prognosis acute myelogenous leukemia 2 - biological and molecular biological characteristics and treatment outcome. Leukemia Res., 2000, 24, 777-789.
-
(2000)
Leukemia Res
, vol.24
, pp. 777-789
-
-
Li, B.1
Yang, J.2
Tao, M.3
Nayini, J.4
Horvath, E.5
Chopra, H.6
Meyer, P.7
Venugopal, P.8
Preisler, H.D.9
-
70
-
-
12944332006
-
Suppression of telomerase activity and cytokine messenger RNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and interleukin 4
-
Preisler, H.D.; Li, B.; Yang, B.L.; Huang, R.W.; Devemy, E.; Venugopal, P.; Tao, M.; Chopra, H.; Gregory, S.A.; Adler, S.; Sivaraman, S.; Toofanfard, P.; Jajeh, A.; Galvez, A.; Robin, E. Suppression of telomerase activity and cytokine messenger RNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and interleukin 4. Clin. Cancer Res., 2000, 6, 807-812.
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 807-812
-
-
Preisler, H.D.1
Li, B.2
Yang, B.L.3
Huang, R.W.4
Devemy, E.5
Venugopal, P.6
Tao, M.7
Chopra, H.8
Gregory, S.A.9
Adler, S.10
Sivaraman, S.11
Toofanfard, P.12
Jajeh, A.13
Galvez, A.14
Robin, E.15
-
71
-
-
0029767457
-
Use of amifostine in bone marrow purging
-
Cagnoni, P.J.; Jones, R.B.; Bearman, S.I.; Ross, M.; Hami, L.; Franklin, W.A.; Capizzi, R.; Schein, P.S.; Shpall, E.J. Use of amifostine in bone marrow purging. Semin. Oncol., 1996, 23, 44-48.
-
(1996)
Semin. Oncol
, vol.23
, pp. 44-48
-
-
Cagnoni, P.J.1
Jones, R.B.2
Bearman, S.I.3
Ross, M.4
Hami, L.5
Franklin, W.A.6
Capizzi, R.7
Schein, P.S.8
Shpall, E.J.9
-
72
-
-
0029743651
-
Amifostine protects primitive hematopoietic progenitors against chemotherapy cytotoxicity
-
List, A.F.; Heaton, R.; Glinsmann-Gibson, B.; Capizzi, R.L. Amifostine protects primitive hematopoietic progenitors against chemotherapy cytotoxicity. Semin. Oncol., 1996, 23, 58-63.
-
(1996)
Semin. Oncol
, vol.23
, pp. 58-63
-
-
List, A.F.1
Heaton, R.2
Glinsmann-Gibson, B.3
Capizzi, R.L.4
-
73
-
-
0032994129
-
Use of amifostine in hematologic malignancies, myelodysplastic syndrome, and acute leukemia
-
List, A.F. Use of amifostine in hematologic malignancies, myelodysplastic syndrome, and acute leukemia. Semin. Oncol., 1999, 26, 61-67.
-
(1999)
Semin. Oncol
, vol.26
, pp. 61-67
-
-
List, A.F.1
-
74
-
-
0031705387
-
Amifostine stimulates formation of multipotent and erythroid bone marrow progenitors
-
List, A.F.; Heaton, R.; Glinsmann-Gibson, B.; Capizzi, R.L. Amifostine stimulates formation of multipotent and erythroid bone marrow progenitors. Leukemia, 1998, 12, 1596-1602.
-
(1998)
Leukemia
, vol.12
, pp. 1596-1602
-
-
List, A.F.1
Heaton, R.2
Glinsmann-Gibson, B.3
Capizzi, R.L.4
-
75
-
-
0030735082
-
Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome
-
List, A.F.; Brasfield, F.; Heaton, R.; Glinsmann-Gibson, B.; Crook, L.; Taetle, R.; Capizzi, R.L. Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome. Blood, 1997, 90, 3364-3369.
-
(1997)
Blood
, vol.90
, pp. 3364-3369
-
-
List, A.F.1
Brasfield, F.2
Heaton, R.3
Glinsmann-Gibson, B.4
Crook, L.5
Taetle, R.6
Capizzi, R.L.7
-
76
-
-
70349390051
-
-
Amifostine. USP DI. Drug information for the health care professional. 20th Ed, Englewood, Colorado: Micromedex, Inc.; 2002, 1.
-
Amifostine. USP DI. Drug information for the health care professional. 20th Ed, Englewood, Colorado: Micromedex, Inc.; 2002, Vol. 1.
-
-
-
-
77
-
-
34247172579
-
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells
-
Qin, H.; Yu, T.; Qing, T.; Liu, Y.; Zhao, Y.; Cai, J.; Li, J.; Song, Z.; Qu, X.; Zhou, P.; Wu, J.; Ding, M.; Deng, H. Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J. Biol. Chem., 2007, 282, 5842-5852.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 5842-5852
-
-
Qin, H.1
Yu, T.2
Qing, T.3
Liu, Y.4
Zhao, Y.5
Cai, J.6
Li, J.7
Song, Z.8
Qu, X.9
Zhou, P.10
Wu, J.11
Ding, M.12
Deng, H.13
-
78
-
-
0030267395
-
Telling cells their time is up
-
Nagata, S. Apoptosis: Telling cells their time is up. Curr. Biol., 1996, 6, 1241-1243.
-
(1996)
Curr. Biol
, vol.6
, pp. 1241-1243
-
-
Nagata, S.A.1
-
79
-
-
2342516817
-
P53 in aging, cancer and IGF signaling
-
Campisi, J. Fragile fugue: P53 in aging, cancer and IGF signaling. Nat. Med., 2004, 10, 231-232.
-
(2004)
Nat. Med
, vol.10
, pp. 231-232
-
-
Campisi1
Fragile fugue, J.2
-
80
-
-
37349082496
-
Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity
-
Lynette, M.; Lu, X.; Nader, G.; Stuart, T.; Lawrence A.D. Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity. Mech. ageing dev., 2007, 128, 717-730.
-
(2007)
Mech. ageing dev
, vol.128
, pp. 717-730
-
-
Lynette, M.1
Lu, X.2
Nader, G.3
Stuart, T.4
Lawrence, A.D.5
-
81
-
-
0038168188
-
Calpains mediate p53 activation and neuronal death evoked by DNA damage
-
Sedarous, M.; Keramaris, E.; O'Hare, M.; Melloni, E.; Slack, R.S.; Elce, J.S.; Greer, P.A.; Park, D.S. Calpains mediate p53 activation and neuronal death evoked by DNA damage. J. Biol. Chem., 2003, 278, 26031-26038.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26031-26038
-
-
Sedarous, M.1
Keramaris, E.2
O'Hare, M.3
Melloni, E.4
Slack, R.S.5
Elce, J.S.6
Greer, P.A.7
Park, D.S.8
-
82
-
-
0035887446
-
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation
-
Castedo, M.; Ferri, K.F.; Blanco, J.; Roumier, T.; Larochette, N.; Barretina, J.; Amendola, A.; Nardacci, R.; Metivier, D.; Este, J.A.; Piacentini, M.; Kroemer, G. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J. Exp. Med., 2001, 194, 1097-1110.
-
(2001)
J. Exp. Med
, vol.194
, pp. 1097-1110
-
-
Castedo, M.1
Ferri, K.F.2
Blanco, J.3
Roumier, T.4
Larochette, N.5
Barretina, J.6
Amendola, A.7
Nardacci, R.8
Metivier, D.9
Este, J.A.10
Piacentini, M.11
Kroemer, G.12
-
83
-
-
33847422145
-
Central role of p53 in the suntan response and pathologic hyperpigmentation
-
Cui, R.; Widlund, H.R.; Feige, E.; Lin, J.Y.; Wilensky, D.L.; Igras, V.E.; D'Orazio, J.; Fung, C.Y.; Schanbacher, C.F.; Granter, S.R.; Fisher, D.E. Central role of p53 in the suntan response and pathologic hyperpigmentation. Cell, 2007, 128, 853-864.
-
(2007)
Cell
, vol.128
, pp. 853-864
-
-
Cui, R.1
Widlund, H.R.2
Feige, E.3
Lin, J.Y.4
Wilensky, D.L.5
Igras, V.E.6
D'Orazio, J.7
Fung, C.Y.8
Schanbacher, C.F.9
Granter, S.R.10
Fisher, D.E.11
-
84
-
-
20444375511
-
Proteolytic mechanisms in necrotic cell death and neurodegeneration
-
Artal-Sanz, M.; Tavernarakis, N. Proteolytic mechanisms in necrotic cell death and neurodegeneration. FEBS Lett., 2005, 579, 3287-3296.
-
(2005)
FEBS Lett
, vol.579
, pp. 3287-3296
-
-
Artal-Sanz, M.1
Tavernarakis, N.2
-
85
-
-
0035938889
-
Does apoptosis have a role in neurodegeneration?
-
Gibson, R.M. Does apoptosis have a role in neurodegeneration? BMJ, 2001, 322, 1539-1540.
-
(2001)
BMJ
, vol.322
, pp. 1539-1540
-
-
Gibson, R.M.1
-
86
-
-
0030831489
-
Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease
-
de la Monte, S.M.; Sohn, Y.K.; Wands, J.R. Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease. J. Neurol. Sci., 1997, 152, 73-83.
-
(1997)
J. Neurol. Sci
, vol.152
, pp. 73-83
-
-
de la Monte, S.M.1
Sohn, Y.K.2
Wands, J.R.3
-
87
-
-
0030956532
-
p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells
-
Blum, D.; Wu, Y.; Nissou, M.F. Arnaud, S.; Benabid, A.-L.; Verna, J.M. p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells. Brain Res., 1997, 751, 139.
-
(1997)
Brain Res
, vol.751
, pp. 139
-
-
Blum, D.1
Wu, Y.2
Nissou, M.F.3
Arnaud, S.4
Benabid, A.-L.5
Verna, J.M.6
-
88
-
-
0027985453
-
Attenuation of p53 expression protects against focal ischemic damage in transgenic mice
-
Crumrine, R.C.; Thomas, A.L.; Morgan, P.F. Attenuation of p53 expression protects against focal ischemic damage in transgenic mice. J. Cerebr. Blood Flow Metab., 1994, 14, 887-891.
-
(1994)
J. Cerebr. Blood Flow Metab
, vol.14
, pp. 887-891
-
-
Crumrine, R.C.1
Thomas, A.L.2
Morgan, P.F.3
-
89
-
-
0033059025
-
-
Napieralski, J.A.; Raghupathi, R.; McIntosh, T.K. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Mol. Brain Res., 1999, 71, 78-86.
-
Napieralski, J.A.; Raghupathi, R.; McIntosh, T.K. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Mol. Brain Res., 1999, 71, 78-86.
-
-
-
-
90
-
-
0033568860
-
Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons
-
Cregan, S.P.; MacLaurin, J.G.; Craig, C.G.; Robertson, G.S.; Nicholson, D.W.; Park, D.S.; Slack, R.S. Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons. J. Neurosci., 1999, 19, 7860-7869.
-
(1999)
J. Neurosci
, vol.19
, pp. 7860-7869
-
-
Cregan, S.P.1
MacLaurin, J.G.2
Craig, C.G.3
Robertson, G.S.4
Nicholson, D.W.5
Park, D.S.6
Slack, R.S.7
-
91
-
-
17644434288
-
Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment
-
Sakhi, S.; Bruce, A.; Sun, N. Tocco G, Baudry, M.; Schreiber, S.S. Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment. Exp. Neurol., 1997, 145, 81-88.
-
(1997)
Exp. Neurol
, vol.145
, pp. 81-88
-
-
Sakhi, S.1
Bruce, A.2
Sun, N.3
Tocco, G.4
Baudry, M.5
Schreiber, S.S.6
-
92
-
-
0029915857
-
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death
-
Morrison, R.S.; Wenzel, H.J.; Kinoshita, Y. Robbins, C.A.; Donehower, L.A.; Schwartzkroin, P.A. Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death. J. Neurosci., 1996, 16, 1337-1345.
-
(1996)
J. Neurosci
, vol.16
, pp. 1337-1345
-
-
Morrison, R.S.1
Wenzel, H.J.2
Kinoshita, Y.3
Robbins, C.A.4
Donehower, L.A.5
Schwartzkroin, P.A.6
-
93
-
-
0030249597
-
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
-
Trimmer, P.A.; Smith, T.S.; Jung, A.B.; Bennett, J.P. Jr. Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration, 1996, 5, 233-239.
-
(1996)
Neurodegeneration
, vol.5
, pp. 233-239
-
-
Trimmer, P.A.1
Smith, T.S.2
Jung, A.B.3
Bennett Jr., J.P.4
-
94
-
-
0030840777
-
p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies
-
Hirata, H.; Cadet, J.L. p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies. J. Neurochem., 1997, 69, 780-790.
-
(1997)
J. Neurochem
, vol.69
, pp. 780-790
-
-
Hirata, H.1
Cadet, J.L.2
-
95
-
-
0025091773
-
Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis
-
Williams G.T.; Smith, C.A.; Spooncer, E.; Dexter T.M.; Taylor, D.R. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature, 1990, 343, 76-79
-
(1990)
Nature
, vol.343
, pp. 76-79
-
-
Williams, G.T.1
Smith, C.A.2
Spooncer, E.3
Dexter, T.M.4
Taylor, D.R.5
-
96
-
-
0025343574
-
Erythropoietin retards DNA break-down and prevents programmed death in erythroid progenitor cells
-
Koury, M.J.; Bondurant, M.C. Erythropoietin retards DNA break-down and prevents programmed death in erythroid progenitor cells. Science, 1990, 248, 378-381.
-
(1990)
Science
, vol.248
, pp. 378-381
-
-
Koury, M.J.1
Bondurant, M.C.2
-
97
-
-
0026630954
-
-
Manabe, A.; Coustan-Smith, E.; Behm, F.G.; Raimondi, S.C.; Campana, D. Blood, 1992, 79, 2370.
-
(1992)
Blood
, vol.79
, pp. 2370
-
-
Manabe, A.1
Coustan-Smith, E.2
Behm, F.G.3
Raimondi, S.C.4
Campana, D.5
-
98
-
-
0027409958
-
Hypothesis: Apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndrome
-
Yoshida, Y. Hypothesis: Apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndrome. Leukemia, 1993, 7, 144-146.
-
(1993)
Leukemia
, vol.7
, pp. 144-146
-
-
Yoshida, Y.1
-
99
-
-
0025645740
-
Apoptosis is a Common Histopathological Finding in Myelodysplasia: The Correlate of Ineffective Haematopoiesis
-
Clark, D.M.; Lampert, I.A. Apoptosis is a Common Histopathological Finding in Myelodysplasia: The Correlate of Ineffective Haematopoiesis. Leukemia Lymphoma, 1990, 2, 415-418.
-
(1990)
Leukemia Lymphoma
, vol.2
, pp. 415-418
-
-
Clark, D.M.1
Lampert, I.A.2
-
100
-
-
0027181636
-
Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe beta-thalassemia (Cooley's anemia)
-
Yuan, J.; Angelucci, E.; Lucarelli, G. Aljurf, M.; Snyder, L.M.; Kiefer, C.R.; Ma, L.; Schrier, S.L.. Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe beta-thalassemia (Cooley's anemia). Blood, 1993, 82, 374-377.
-
(1993)
Blood
, vol.82
, pp. 374-377
-
-
Yuan, J.1
Angelucci, E.2
Lucarelli, G.3
Aljurf, M.4
Snyder, L.M.5
Kiefer, C.R.6
Ma, L.7
Schrier, S.L.8
-
101
-
-
0037375684
-
Mitochondria as a target for inducing death of malignant hematopoietic cells
-
Solary, E.; Bettaieb, A.; Dubrez-Daloz, L.; Corcos, L. Mitochondria as a target for inducing death of malignant hematopoietic cells. Leukemia Lymphoma, 2003, 44, 563-564.
-
(2003)
Leukemia Lymphoma
, vol.44
, pp. 563-564
-
-
Solary, E.1
Bettaieb, A.2
Dubrez-Daloz, L.3
Corcos, L.4
-
102
-
-
7444224713
-
Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions
-
Hussein M.R.; Al-Badaiwy, Z.H.; Guirguis, M.N. Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions. J. Cutan. Pathol., 2004, 31, 643-651.
-
(2004)
J. Cutan. Pathol
, vol.31
, pp. 643-651
-
-
Hussein, M.R.1
Al-Badaiwy, Z.H.2
Guirguis, M.N.3
-
103
-
-
0034814136
-
Influenza A virus infection of mice induces nuclear accumulation of the tumorsuppressor protein p53 in the lung
-
Technau-Ihling, K., Ihling, C.; Kromeier, J.; Brandner, G. Influenza A virus infection of mice induces nuclear accumulation of the tumorsuppressor protein p53 in the lung. Arch. Virol., 2001, 146, 1655-1666.
-
(2001)
Arch. Virol
, vol.146
, pp. 1655-1666
-
-
Technau-Ihling, K.1
Ihling, C.2
Kromeier, J.3
Brandner, G.4
-
104
-
-
21644454525
-
-
Turpin, E.; Luke, K.; Jones, J.; Tumpey, T.; Konan, K.; Schultz-Cherry, S. Influenza virus infection increases p53 activity: Role of p53 in cell death and viral replication. J. Virol., 2005, 79, 8802-8811.
-
Turpin, E.; Luke, K.; Jones, J.; Tumpey, T.; Konan, K.; Schultz-Cherry, S. Influenza virus infection increases p53 activity: Role of p53 in cell death and viral replication. J. Virol., 2005, 79, 8802-8811.
-
-
-
-
105
-
-
33745160721
-
Comparative analysis of mycobacterial heat shock proteins-induced apoptosis of peripheral blood mononuclear cells in sarcoidosis and tuberculosis
-
Dubaniewicz, A.; Trzonkowski, P.; Dubaniewicz-Wybieralska, M.; Dubaniewicz, A.; Singh, M.; Mysliwski, A. Comparative analysis of mycobacterial heat shock proteins-induced apoptosis of peripheral blood mononuclear cells in sarcoidosis and tuberculosis. J. Clin. Immunol., 2006, 26, 243-250.
-
(2006)
J. Clin. Immunol
, vol.26
, pp. 243-250
-
-
Dubaniewicz, A.1
Trzonkowski, P.2
Dubaniewicz-Wybieralska, M.3
Dubaniewicz, A.4
Singh, M.5
Mysliwski, A.6
-
106
-
-
25444505016
-
Apoptosis in human skin: Role in pathogenesis of various diseases and relevance for therapy
-
Reefman, E.; Limberg, P.C.; Kallenberg, C.G.M.; Bijl, M. Apoptosis in human skin: Role in pathogenesis of various diseases and relevance for therapy. Ann. N. Y. Acad. Sci., 2005, 1051, 52-63
-
(2005)
Ann. N. Y. Acad. Sci
, vol.1051
, pp. 52-63
-
-
Reefman, E.1
Limberg, P.C.2
Kallenberg, C.G.M.3
Bijl, M.4
-
107
-
-
0037412501
-
An investigation of apoptosis in androgenetic alopecia
-
Morgan, M.B.; Rose, P. An investigation of apoptosis in androgenetic alopecia. Ann. Clin. Lab. Sci., 2003, 33, 107-112
-
(2003)
Ann. Clin. Lab. Sci
, vol.33
, pp. 107-112
-
-
Morgan, M.B.1
Rose, P.2
-
108
-
-
0004159897
-
-
2nd Ed, Blackwell Publishing Ltd, Oxford
-
van de Kerkhof, P. Textbook of psoriasis, 2nd Ed., Blackwell Publishing Ltd., Oxford, 2003, pp. 83-109.
-
(2003)
Textbook of psoriasis
, pp. 83-109
-
-
van de Kerkhof, P.1
-
109
-
-
0026010995
-
Molecular themes in oncogenesis
-
Bishop, J.M. Molecular themes in oncogenesis. Cell, 1991, 64, 235-248.
-
(1991)
Cell
, vol.64
, pp. 235-248
-
-
Bishop, J.M.1
-
110
-
-
0026059515
-
Tumor suppressor genes
-
Marshall, C.J. Tumor suppressor genes. Cell, 1991, 64, 313-326.
-
(1991)
Cell
, vol.64
, pp. 313-326
-
-
Marshall, C.J.1
-
111
-
-
0024823407
-
P53 and oncogenes expression in psoriasis
-
Tadini, G.; Cerri, A.; Crosti, L. Cattoretti, G.; Berti, E. P53 and oncogenes expression in psoriasis. Acta Derm. Venereol. Suppl., 1989, 146, 33-35.
-
(1989)
Acta Derm. Venereol. Suppl
, vol.146
, pp. 33-35
-
-
Tadini, G.1
Cerri, A.2
Crosti, L.3
Cattoretti, G.4
Berti, E.5
-
112
-
-
0027378327
-
Expression of p53 protein in benign and malignant epidermal pathologic conditions
-
Helander, S.D.; Peters, M.S.; Pittelkow, M.R. Expression of p53 protein in benign and malignant epidermal pathologic conditions. J. Am. Acad. Dermatol., 1993, 29, 741-748.
-
(1993)
J. Am. Acad. Dermatol
, vol.29
, pp. 741-748
-
-
Helander, S.D.1
Peters, M.S.2
Pittelkow, M.R.3
-
113
-
-
0027945823
-
Aberrant accumulation of p53 associates with Ki67 and mitotic count in benign skin lesions
-
Soini, Y.; Kamel, D.; Paakko, P.; Lehto, V.P.; Oikarinen, A.; Vahakangas, K.V. Aberrant accumulation of p53 associates with Ki67 and mitotic count in benign skin lesions. Br. J. Dermatol., 1994, 131, 514-520.
-
(1994)
Br. J. Dermatol
, vol.131
, pp. 514-520
-
-
Soini, Y.1
Kamel, D.2
Paakko, P.3
Lehto, V.P.4
Oikarinen, A.5
Vahakangas, K.V.6
-
114
-
-
0032972108
-
Expression of p53 protein before and after PUVA treatment in psoriasis
-
Hannuksela-Svahn, A.; Paakko, P.; Autio, P.; Reunala, T.; Karvonen, J.; Vähäkangas, K. Expression of p53 protein before and after PUVA treatment in psoriasis. Acta Derm. Venereol., 1999, 79, 195-199.
-
(1999)
Acta Derm. Venereol
, vol.79
, pp. 195-199
-
-
Hannuksela-Svahn, A.1
Paakko, P.2
Autio, P.3
Reunala, T.4
Karvonen, J.5
Vähäkangas, K.6
-
115
-
-
24744431627
-
Expression of p53 protein in psoriasis
-
Baran, W.; Szepietowski, J.C.; Szybejko-Machaj, G. Expression of p53 protein in psoriasis. Acta dermatoven APA, 2005, 14, 79-83.
-
(2005)
Acta dermatoven APA
, vol.14
, pp. 79-83
-
-
Baran, W.1
Szepietowski, J.C.2
Szybejko-Machaj, G.3
-
116
-
-
0029008768
-
From cell activation to cell depletion. The programmed cell death hypothesis of AIDS pathogenesis
-
Ameisen, J.C. From cell activation to cell depletion. The programmed cell death hypothesis of AIDS pathogenesis. Adv. Exp. Med. Biol., 1995, 374, 139-163.
-
(1995)
Adv. Exp. Med. Biol
, vol.374
, pp. 139-163
-
-
Ameisen, J.C.1
-
117
-
-
0033367053
-
Apoptosis and disease
-
Chamond, R.R.; Anon, J.C.; Aguilar, C.M.; Pasadas, F.G. Apoptosis and disease. Alergol. Immunol. Clin., 1999, 14, 367-374.
-
(1999)
Alergol. Immunol. Clin
, vol.14
, pp. 367-374
-
-
Chamond, R.R.1
Anon, J.C.2
Aguilar, C.M.3
Pasadas, F.G.4
-
118
-
-
33645833422
-
Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands
-
Ishimaru, N.; Arakaki, R.; Omotehara, F.; Yamada, K.; Mishima, K.; Saito, I.; Hayashi, Y. Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands. Mol. Cell Biol., 2006, 26, 2924-2935.
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 2924-2935
-
-
Ishimaru, N.1
Arakaki, R.2
Omotehara, F.3
Yamada, K.4
Mishima, K.5
Saito, I.6
Hayashi, Y.7
-
119
-
-
0028288510
-
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
-
Casciola-Rosen, L.A.; Anhalt, G.; rosen, A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med., 1994, 179, 1317-1330.
-
(1994)
J. Exp. Med
, vol.179
, pp. 1317-1330
-
-
Casciola-Rosen, L.A.1
Anhalt, G.2
rosen, A.3
-
120
-
-
0014587529
-
Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?
-
Li, F.P.; Fraumeni, J.F. Jr. Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann. Intern. Med., 1969, 71, 747-752.
-
(1969)
Ann. Intern. Med
, vol.71
, pp. 747-752
-
-
Li, F.P.1
Fraumeni Jr., J.F.2
-
121
-
-
0025633582
-
-
Malkin, D.; Li, F.P.; Strong, L.C.; Fraumeni, J.F. Jr.; Nelson, C.E.; Kim DH, Kassel, J.; Gryka, M.A.; Bischoff, F.Z.; Tainsky, M.A. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science, 1990, 250, 1233- 238.
-
Malkin, D.; Li, F.P.; Strong, L.C.; Fraumeni, J.F. Jr.; Nelson, C.E.; Kim DH, Kassel, J.; Gryka, M.A.; Bischoff, F.Z.; Tainsky, M.A. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science, 1990, 250, 1233- 238.
-
-
-
-
122
-
-
0032522623
-
Multiple primary cancers in families with Li-Fraumeni syndrome
-
Hisada, M.; Garber, J.E.; Fung, C.Y.; Fraumeni, J.F. Jr.; Li, F.P. Multiple primary cancers in families with Li-Fraumeni syndrome. J. Natl. Cancer Inst., 1998, 90, 606-611.
-
(1998)
J. Natl. Cancer Inst
, vol.90
, pp. 606-611
-
-
Hisada, M.1
Garber, J.E.2
Fung, C.Y.3
Fraumeni Jr., J.F.4
Li, F.P.5
-
123
-
-
0030806921
-
Germline mutations of TP53 in Li-Fraumeni families: An extended study of 39 families
-
Varley, J.M.; McGown, G.; Thorncroft, M.; Santibanez-Koref, M.F.; Kelsey, A.M.; Tricker, K.J. Evans, D.G.; Birch, J.M. Germline mutations of TP53 in Li-Fraumeni families: An extended study of 39 families. Cancer Res., 1997, 57, 3245-3252.
-
(1997)
Cancer Res
, vol.57
, pp. 3245-3252
-
-
Varley, J.M.1
McGown, G.2
Thorncroft, M.3
Santibanez-Koref, M.F.4
Kelsey, A.M.5
Tricker, K.J.6
Evans, D.G.7
Birch, J.M.8
-
124
-
-
30044439886
-
Adenovirus p53 gene therapy
-
Roth, J.A. Adenovirus p53 gene therapy. Expert Opin. Biol. Ther., 2006, 6, 55-61.
-
(2006)
Expert Opin. Biol. Ther
, vol.6
, pp. 55-61
-
-
Roth, J.A.1
-
125
-
-
0033709501
-
A patient with 17 primary tumours and a germ line mutation in TP53: Tumour induction by adjuvant therapy?
-
Nutting, C.; Camplejohn, R.S.; Gilchrist, R.; Tait, D.; Blake, P.; Knee, G.; Yao, W.Q.; Ross, G.; Fisher, C.; Eeles, R. A patient with 17 primary tumours and a germ line mutation in TP53: Tumour induction by adjuvant therapy? Clin. Oncol. (R Coll Radiol), 2000, 12, 300-304.
-
(2000)
Clin. Oncol. (R Coll Radiol)
, vol.12
, pp. 300-304
-
-
Nutting, C.1
Camplejohn, R.S.2
Gilchrist, R.3
Tait, D.4
Blake, P.5
Knee, G.6
Yao, W.Q.7
Ross, G.8
Fisher, C.9
Eeles, R.10
-
126
-
-
0035921190
-
Two metachronous tumors in the radiotherapy fields of a patient with Li-Fraumeni syndrome
-
Limacher, J.M.; Frebourg, T.; Natarajan-Ame, S.; Bergerat, J.P. Two metachronous tumors in the radiotherapy fields of a patient with Li-Fraumeni syndrome. Int. J. Cancer, 2001, 96, 238-242.
-
(2001)
Int. J. Cancer
, vol.96
, pp. 238-242
-
-
Limacher, J.M.1
Frebourg, T.2
Natarajan-Ame, S.3
Bergerat, J.P.4
-
127
-
-
0345269984
-
Germline p53 mutations in a cohort with childhood sarcoma: Sex differences in cancer risk
-
Hwang, S.J.; Lozano, G.; Amos, C.I.; Strong, L.C. Germline p53 mutations in a cohort with childhood sarcoma: Sex differences in cancer risk. Am. J. Hum. Genet., 2003, 72, 975-983.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 975-983
-
-
Hwang, S.J.1
Lozano, G.2
Amos, C.I.3
Strong, L.C.4
-
128
-
-
0042199085
-
Nonclinical toxicology in support of licensure of gene therapies
-
Frederickson, R.M.; Carter, B.J.; Pilaro, A.M. Nonclinical toxicology in support of licensure of gene therapies. Mol. Ther., 2003, 8, 8-10.
-
(2003)
Mol. Ther
, vol.8
, pp. 8-10
-
-
Frederickson, R.M.1
Carter, B.J.2
Pilaro, A.M.3
-
129
-
-
34250728105
-
-
Senzer, N.; Nemunaitis, J.; Nemunaitis, M.; Lamont, J.; Gore, M.; Gabra, H.; Eeles, R.; Sodha, N.; Lynch, F.J.; Zumstein, L.A.; Menander, K.B.; Sobol, R.E.; Chada, S. p53 therapy in a patient with Li-Fraumeni syndrome. Mol. Cancer Ther., 2007, 6, 1478- 482.
-
Senzer, N.; Nemunaitis, J.; Nemunaitis, M.; Lamont, J.; Gore, M.; Gabra, H.; Eeles, R.; Sodha, N.; Lynch, F.J.; Zumstein, L.A.; Menander, K.B.; Sobol, R.E.; Chada, S. p53 therapy in a patient with Li-Fraumeni syndrome. Mol. Cancer Ther., 2007, 6, 1478- 482.
-
-
-
-
130
-
-
0029035757
-
Apoptosis and loss of renal tissue in polycystic kidney diseases
-
Woo, D. Apoptosis and loss of renal tissue in polycystic kidney diseases. New Engl. J. Med., 1995, 333, 18-25.
-
(1995)
New Engl. J. Med
, vol.333
, pp. 18-25
-
-
Woo, D.1
-
131
-
-
21044445452
-
Apoptosis: A mechanism of acute and chronic liver injury
-
Guicciardi, M.E.; Gores, G.J. Apoptosis: A mechanism of acute and chronic liver injury. Gut, 2005, 54, 1024-1033
-
(2005)
Gut
, vol.54
, pp. 1024-1033
-
-
Guicciardi, M.E.1
Gores, G.J.2
-
132
-
-
0027363543
-
Apoptotic bodies in a murine model of alcoholic liver disease: Reversibility of ethanol-induced changes
-
Goldin, R.D.; Hunt, N.C.; Clark, J.; Wickramassinghe, S.N. Apoptotic bodies in a murine model of alcoholic liver disease: Reversibility of ethanol-induced changes. J. Pathol., 1993, 171, 73-76.
-
(1993)
J. Pathol
, vol.171
, pp. 73-76
-
-
Goldin, R.D.1
Hunt, N.C.2
Clark, J.3
Wickramassinghe, S.N.4
-
133
-
-
0027967063
-
Reperfusion injury induces apoptosis in rabbit cardiomyocytes
-
Gottlieb, R.A.; Burleson, K.O.; Kloner, R.A.; Babior, B.M.; Engler, R.L. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J. Clin. Invest., 1994, 94, 1621-1628.
-
(1994)
J. Clin. Invest
, vol.94
, pp. 1621-1628
-
-
Gottlieb, R.A.1
Burleson, K.O.2
Kloner, R.A.3
Babior, B.M.4
Engler, R.L.5
-
134
-
-
33748928423
-
The role of p53 in atherosclerosis
-
Mercer, J.; Bennett, M. The role of p53 in atherosclerosis. Cell Cycle, 2006, 5, 1907-1909.
-
(2006)
Cell Cycle
, vol.5
, pp. 1907-1909
-
-
Mercer, J.1
Bennett, M.2
-
135
-
-
0027156167
-
Impairment of function in aging neutrophils is associated with apoptosis
-
Whyte, M.K.B.; Meagher, L.C.; MacDermot, J.; Haslett, C. Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol., 1993, 150, 5124-5134.
-
(1993)
J. Immunol
, vol.150
, pp. 5124-5134
-
-
Whyte, M.K.B.1
Meagher, L.C.2
MacDermot, J.3
Haslett, C.4
-
136
-
-
0025042930
-
Programmed cell death: New thoughts and relevance to aging
-
Lockshin, R.A.; Zackeri, Z.F. Programmed cell death: New thoughts and relevance to aging. J. Gerontol., 1990, 45, 135-140.
-
(1990)
J. Gerontol
, vol.45
, pp. 135-140
-
-
Lockshin, R.A.1
Zackeri, Z.F.2
-
137
-
-
44449137138
-
Cyclic pifithrin-α sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis
-
Zuco, V.; Zunino, F. Cyclic pifithrin-α sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. Neoplasia, 2008, 10, 587-596.
-
(2008)
Neoplasia
, vol.10
, pp. 587-596
-
-
Zuco, V.1
Zunino, F.2
-
138
-
-
0030784938
-
Motor complications of chronic levodopa therapy in Parkinson's disease
-
Miyawaki, E.; Lyons, K.; Pahwa, R. Motor complications of chronic levodopa therapy in Parkinson's disease. Clin. Neuropharmacol., 1997, 20, 523-530.
-
(1997)
Clin. Neuropharmacol
, vol.20
, pp. 523-530
-
-
Miyawaki, E.1
Lyons, K.2
Pahwa, R.3
-
139
-
-
70349377386
-
-
Lemke, T.L., Williams, D.A., Roche, V.F., Zito, S.W. In Foye's principles of medicinal chemistry, Booth R.G., 6th Ed.; Wolters Kluwer India Pvt. Ltd., New Delhi, 2008, pp. 679-697.
-
Lemke, T.L., Williams, D.A., Roche, V.F., Zito, S.W. In Foye's principles of medicinal chemistry, Booth R.G., 6th Ed.; Wolters Kluwer India Pvt. Ltd., New Delhi, 2008, pp. 679-697.
-
-
-
-
140
-
-
0028870394
-
Genomic instability and the role of p53 mutations in cancer cells
-
Smith, M.L.; Fornace, A.J.J. Genomic instability and the role of p53 mutations in cancer cells. Curr Opin Oncol., 1995, 7, 69-75.
-
(1995)
Curr Opin Oncol
, vol.7
, pp. 69-75
-
-
Smith, M.L.1
Fornace, A.J.J.2
-
141
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe, S.W.; Ruley, H.E.; Jacks, T.; Housman, D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 1993, 74, 957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
142
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz, F.; Hwang, P.M.; Torrance, C.; Waldman, T.; Zhang, Y.; Dillehay, L.; Williams, J.; Lengauer, C.; Kinzler, K.W.; Vegelstein, B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Invest., 1999, 104, 263-269.
-
(1999)
J. Clin. Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vegelstein, B.10
-
143
-
-
0027459198
-
Mdm2 expression is induced by wild-type p53 activity
-
Barak, Y.; Juven, T.; Haffner, R.; Oren, M. Mdm2 expression is induced by wild-type p53 activity. EMBO J., 1993, 12, 461-468.
-
(1993)
EMBO J
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
144
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J.; Zambetti, G.P.; Olson, D.C.; George, D.; Levine, A.J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 1992, 69, 1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
145
-
-
0027248782
-
Sequence-specific DNA binding by p53: Identification of target sites and lack of binding to p53-MDM2 complexes
-
Zauberman, A.; Barak, Y.; Ragimov, N.; Levy, N.; Oren, M. Sequence-specific DNA binding by p53: Identification of target sites and lack of binding to p53-MDM2 complexes. EMBO J., 1993, 12, 2799-2808.
-
(1993)
EMBO J
, vol.12
, pp. 2799-2808
-
-
Zauberman, A.1
Barak, Y.2
Ragimov, N.3
Levy, N.4
Oren, M.5
-
146
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y.; Maya, R.; Kazaz, A.; Oren, M. Mdm2 promotes the rapid degradation of p53. Nature, 1997, 387, 296-299
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
147
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M.H.G.; Jones, S.N.; Vousden, K.H. Regulation of p53 stability by Mdm2. Nature, 1997, 387, 299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.G.1
Jones, S.N.2
Vousden, K.H.3
-
148
-
-
0030577120
-
Papillomavirus infections: A major cause of human cancers
-
zur Hausen, H. Papillomavirus infections: A major cause of human cancers. Biochim. Biophys. Acta, 1996, 1288, F55-F78.
-
(1996)
Biochim. Biophys. Acta
, vol.1288
-
-
zur Hausen, H.1
-
149
-
-
0027079358
-
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
-
Mietz, J.A.; Unger, T.; Huibregtse, J.M.; Howley, P.M. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J., 1992, 11, 5013-5020.
-
(1992)
EMBO J
, vol.11
, pp. 5013-5020
-
-
Mietz, J.A.1
Unger, T.2
Huibregtse, J.M.3
Howley, P.M.4
-
150
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner, M.; Werness, B.A.; Huibregtse, J.M.; Levine, A.J.; Howley, P.M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 1990, 63, 1129-1136.
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
151
-
-
0028855276
-
Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation
-
Truant, R.; Antunovic, J.; Greenblatt, J.; Prives, C.; Cromlish, J.A. Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation. J. Virol., 1995, 69, 1851-1859.
-
(1851)
J. Virol
, vol.1995
, pp. 69
-
-
Truant, R.1
Antunovic, J.2
Greenblatt, J.3
Prives, C.4
Cromlish, J.A.5
-
152
-
-
0028843480
-
Functional inactivation but not structural mutation of p53 causes liver cancer
-
Ueda, H.; Ullrich, S.J.; Gangemi, J.D.; Kappel, C.A.; Ngo, L.; Feitelson, M.A. Functional inactivation but not structural mutation of p53 causes liver cancer. Nat. Genet., 1995, 9, 41-47.
-
(1995)
Nat. Genet
, vol.9
, pp. 41-47
-
-
Ueda, H.1
Ullrich, S.J.2
Gangemi, J.D.3
Kappel, C.A.4
Ngo, L.5
Feitelson, M.A.6
-
153
-
-
0030200222
-
-
Cromlish, J.A. Hepatitis B virus-induced hepatocellular carcinoma: possible roles for HBx. Trends Microbiol., 1996, 4, 270-274.
-
Cromlish, J.A. Hepatitis B virus-induced hepatocellular carcinoma: possible roles for HBx. Trends Microbiol., 1996, 4, 270-274.
-
-
-
|